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The map label for this gene is rsbRA [H]

Identifier: 222524702

GI number: 222524702

Start: 1816059

End: 1816922

Strand: Reverse

Name: rsbRA [H]

Synonym: Chy400_1429

Alternate gene names: 222524702

Gene position: 1816922-1816059 (Counterclockwise)

Preceding gene: 222524703

Following gene: 222524701

Centisome position: 34.48

GC content: 52.78

Gene sequence:

>864_bases
ATGCCCCAGGTCATTGCTAACATCGTCGCCTTCTGCGAGGCACGCCTGGTCGAAACTGCTGAACGGTTTACCGATGAGCT
TCGTAACCGCCACGCAAACTATGCGGCCATGGATCGGGCTGTACTGCTGCAAGCGGTAACGACGTCGCTTAAGACACTGA
TCCAGGCGATTGGAACCGGCGATTTGAAACCATTTCTTGACCATGCCCGCTCAATTGGTAAGGCACGGGCCAGTAGTGGG
TTCATTGCCGCCGATATGTTCGGTGCCTTGAATGAATTGCGCCGCATTGCCTGGAGTCTGATAGAGGATTTTAATCGCGA
ACATCAGACGGTGACCGTTAATCATGTGCGGCGATTAGAAGATATTATTCACGCTTTTGGACAGGAATTACTCACCAGTT
TTAGCGTTATGTATCGTGATGTGCAGCTTCAGATCAATGATCAGGCTGCACAGATCGCGGCTCAACAGCAGACTATTCGT
GAGTTGAGCACACCGATCCTCCCGCTCTACGAAGGTATTCTGGTTGTGCCACTGGTCGGGGTGATTGATAGCTTCCGTGC
CGGCCAGATCATGGAACGCCTGCTCACCGCAATTGCCGAACGTCAATCAGACATCGTGATTATTGACATCACCGGCGTGC
CGGTGATCGATACCGCAGTTGCGAATTATCTCTTACAGGCGGCACGGGCAGCACAATTGATCGGGGCACAGGTGATTCTG
GTCGGTATTGGCCCGGAAATTGCCCAAACTCTTGTGCAACTTGGAGTTGATCTGAGTGGCATCCAGGTCGGAGCAACCTT
GCAAACCGGGATCGAGCTGGCACTCCAGCGTACCGGCCATGAAATAAGACCACTGCAACGATAG

Upstream 100 bases:

>100_bases
TGATCTGCGTGGAATCCAGATCGGCGCCAATCTTCAGGCCGGCATTGAACTGGCATTAAGTCAGCAAGGCTACACCATTC
GCTGATCAGGTGAGGTACTG

Downstream 100 bases:

>100_bases
ACGCCAATCGCAGGCTGTCGCCATCTGGTTACGGAAACCTTGCCCTACGCTCCGCAGACAAGCGTGTGTTAACGGGTGTT
TGACGTCGCATCCTTTCCGA

Product: anti-sigma-factor antagonist

Products: NA

Alternate protein names: Stressosome protein rsbRA [H]

Number of amino acids: Translated: 287; Mature: 286

Protein sequence:

>287_residues
MPQVIANIVAFCEARLVETAERFTDELRNRHANYAAMDRAVLLQAVTTSLKTLIQAIGTGDLKPFLDHARSIGKARASSG
FIAADMFGALNELRRIAWSLIEDFNREHQTVTVNHVRRLEDIIHAFGQELLTSFSVMYRDVQLQINDQAAQIAAQQQTIR
ELSTPILPLYEGILVVPLVGVIDSFRAGQIMERLLTAIAERQSDIVIIDITGVPVIDTAVANYLLQAARAAQLIGAQVIL
VGIGPEIAQTLVQLGVDLSGIQVGATLQTGIELALQRTGHEIRPLQR

Sequences:

>Translated_287_residues
MPQVIANIVAFCEARLVETAERFTDELRNRHANYAAMDRAVLLQAVTTSLKTLIQAIGTGDLKPFLDHARSIGKARASSG
FIAADMFGALNELRRIAWSLIEDFNREHQTVTVNHVRRLEDIIHAFGQELLTSFSVMYRDVQLQINDQAAQIAAQQQTIR
ELSTPILPLYEGILVVPLVGVIDSFRAGQIMERLLTAIAERQSDIVIIDITGVPVIDTAVANYLLQAARAAQLIGAQVIL
VGIGPEIAQTLVQLGVDLSGIQVGATLQTGIELALQRTGHEIRPLQR
>Mature_286_residues
PQVIANIVAFCEARLVETAERFTDELRNRHANYAAMDRAVLLQAVTTSLKTLIQAIGTGDLKPFLDHARSIGKARASSGF
IAADMFGALNELRRIAWSLIEDFNREHQTVTVNHVRRLEDIIHAFGQELLTSFSVMYRDVQLQINDQAAQIAAQQQTIRE
LSTPILPLYEGILVVPLVGVIDSFRAGQIMERLLTAIAERQSDIVIIDITGVPVIDTAVANYLLQAARAAQLIGAQVILV
GIGPEIAQTLVQLGVDLSGIQVGATLQTGIELALQRTGHEIRPLQR

Specific function: Negative regulator of sigma-B activity. Non- phosphorylated rsbS binds to rsbT, preventing its association with rsbU. Requires any one of rsbRA, rsbRB, rsbRC or rsbRD to sequester rsbT. When rsbS and the rsbR paralog(s) are phosphorylated, they release rs

COG id: COG1366

COG function: function code T; Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014792
- InterPro:   IPR002645 [H]

Pfam domain/function: PF08678 Rsbr_N; PF01740 STAS [H]

EC number: NA

Molecular weight: Translated: 31444; Mature: 31313

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: PS50801 STAS ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQVIANIVAFCEARLVETAERFTDELRNRHANYAAMDRAVLLQAVTTSLKTLIQAIGTG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
DLKPFLDHARSIGKARASSGFIAADMFGALNELRRIAWSLIEDFNREHQTVTVNHVRRLE
CCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHH
DIIHAFGQELLTSFSVMYRDVQLQINDQAAQIAAQQQTIRELSTPILPLYEGILVVPLVG
HHHHHHHHHHHHHHHHHHHHHHEEECHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
VIDSFRAGQIMERLLTAIAERQSDIVIIDITGVPVIDTAVANYLLQAARAAQLIGAQVIL
HHHCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHEEE
VGIGPEIAQTLVQLGVDLSGIQVGATLQTGIELALQRTGHEIRPLQR
EECCHHHHHHHHHHCCCCCCEEECHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
PQVIANIVAFCEARLVETAERFTDELRNRHANYAAMDRAVLLQAVTTSLKTLIQAIGTG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
DLKPFLDHARSIGKARASSGFIAADMFGALNELRRIAWSLIEDFNREHQTVTVNHVRRLE
CCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHH
DIIHAFGQELLTSFSVMYRDVQLQINDQAAQIAAQQQTIRELSTPILPLYEGILVVPLVG
HHHHHHHHHHHHHHHHHHHHHHEEECHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
VIDSFRAGQIMERLLTAIAERQSDIVIIDITGVPVIDTAVANYLLQAARAAQLIGAQVIL
HHHCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHEEE
VGIGPEIAQTLVQLGVDLSGIQVGATLQTGIELALQRTGHEIRPLQR
EECCHHHHHHHHHHCCCCCCEEECHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8002610; 9384377; 11157946; 10329124 [H]