| Definition | Chloroflexus sp. Y-400-fl chromosome, complete genome. |
|---|---|
| Accession | NC_012032 |
| Length | 5,268,950 |
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The map label for this gene is gyrA [H]
Identifier: 222524636
GI number: 222524636
Start: 1738784
End: 1741252
Strand: Reverse
Name: gyrA [H]
Synonym: Chy400_1360
Alternate gene names: 222524636
Gene position: 1741252-1738784 (Counterclockwise)
Preceding gene: 222524640
Following gene: 222524627
Centisome position: 33.05
GC content: 58.16
Gene sequence:
>2469_bases ATGGAAATCGGTATCGTCCGGCCCGTCAACATCACCAATGAGATGCGGACGGCCTATCTCAGCTACGCGATGAGCGTCAT CGTCTCGCGTGCGCTCCCTGATGCACGTGATGGCTTGAAGCCGGTGCAGCGCCGTATTCTCTACGGCATGTGGGACATGG GCTTTCGCAGTAATCAGCCATACAAAAAGAGTGCCCGTATCGTGGGCGATGTGCTCGGTAAAATGCACCCCCACGGTGAC AGTGCCGTCTACGATGCGCTGGCCCGCATGGCTCAGCCCTGGAGTATGCGGTATCCCCTGATCGATGGCCAGGGTAACTT CGGTTCCATCGATGGCGATCCGCCCGCAGCGATGCGCTACACCGAAGCGCGCCTGGCGCCAATTGCCGAAGAGTTGCTCA GTGAGATTGAGAAAGATACCGTCGATTTTCGTGATAACTTCGATGGCAGCTACCGCGAGCCGGTCGTGCTCCCGGCCATT CTGCCCAATCTGCTGCTCAACGGTGCTTCCGGGATTGCGGTTGGTATGGCAACCAACATTCCACCGCACAACCTCGGCGA ACTCTGCGATGCGATCAGCTATCTAATCGAACACCCGGAGGCCACGGTTGAGGAGCTGATGAAGATCATCCCCGGCCCTG ACTTTCCAACTGCCGGGCTGATTCTGGGCACCGAGGGGATTTTAGCCGCGTACAGCACCGGGCGTGGGCAGATTACGCTG CGCGCCAAGACACATATCGAAGAGGCCGGGCGCGGTGCCTTTATGATCGTCGTCACCGAATTGCCGTATCAGGTCAACAA GGCTCGTCTGCAAGAGCGAATTGCCGAGCTGGTCAAAGATCGCAAGATCGAGGGTATTCGCGATGTGCGAGATGAGAGCG ACCGCACCGGCATGCGGTTGGTGATCCTTTTGAAACAAGATGCCCAACCCAAGAAGGTGCTCAATGCGCTCTACAAGCAC ACCCAAATGCAGACTACCTTCGGGATCAATATGCTGGCACTGGTCGAGCACGGTCGTCAGCCGCGCGTCTTGACCCTCAA ACGCCTCTTGCAAGAGTACATCACCCACCGGCAAGAGGTTATTCGACGCCGAACCGAGTTCGATCTGGCCCGTGCTCGGG AACGTGCCCACATTCTGGAGGGCTTGAAGATTGCGCTCGATAACCTGGACGCTGTCATTCAGACCATCCGCGACTCGCGA ACTGCTGAGAGCGCCCGCAATAACCTGATGAGTAATTTTTCGCTTACCGAGCGGCAGGCGCAGGCTATCCTCGATCTTCA GTTACGCCGTCTGGCTGCGCTCGAACGCAAGAAGATCGAAGATGAATACCGTGAGGTGATCAAGCTGATCGCCGAACTGG AAGATATTCTGGCCAATCCGCGCAAGGTGTTGCACCTGATCCAGCAAGACCTGACTCGCCTGAAAGAGAAGTATGGCGAT CCGCGGCGCACCCGCATTATTCCTGATGTCACCGGTGAAGTGAGCGACGAAGACCTGATCCCCGATGTGCGGGTGATGAT TACCTTGACCGACCGTGGCTATATCAAGCGTCAGTTACCTGATGCCTACCGCACCCAGCGCCGTGGTGGTCGAGGCATCA AGGGTATGCTGACCAGAGAACAGGATATTGTGCGCCACCTGTTGACGTGCAATTCGCTCGACAACCTGCTCTTCTTCACC GACCGCGGCAAGGTCTATCAACTGAAGGCGCACGAAGTACCCGACAGCTCCCGAACGGCGAAGGGTTTGCCACTGGTAAA CCTGATTTCGCTCGAACCGGGTGAACAGGTGACGTCAATGCTGGCCGTGCGCGAGTTTGATGCCGAGTATCTGGTGATGG CGACGGTGCGCGGGAAGATCAAGCGCACGCAATTGCGTGAGTACAGTCAGGTGCGCTCGAACGGCCTAATCGCGATTGGC CTGGAAGAGGGTGATGTGCTGGGTTGGGTGCGGGTCAGCCACGGCCACGAAGACATCTTGCTGACGACGGCTCGCGGTCA GACGCTGCGTTTCGAGCAGAGCGAAGTGCGACCAATGGGTCGTCCGGCCACCGGCGTGATCGGGATCAACCTGGCAGACG GTGATCGCGTTGTCAGTATGGATCTGGCTGAAGAGGGGGCCGATCTGCTGGTTGTGACTGCGCGAGGGATAGGCAAGCGA ACAGCACTCTCTGAATATCCGGTCAAAGGCCGGGCTACCGGTGGCGTCATTACCATCAAACTGCGCAACGATCTTGACGA AGTTGCTGCTGCGGCGGTTGTCCGTGAGCATTCTCTGCTCACCTTTATCACCACCGGTGGGATGGTATTGCGCACCAGCG CCAGCGAGATCTCACGCCTGGGCCGGGCCACGCAGGGGGTGACCATCGTCAATGTGGCGACCGGTGATCGGGTGGCTGCG CTATCGGTGGAAGACCCGGAAGAGAACGGTAACGGCTCCACGCCGACATTAATCGATCCGTTGTCGTAG
Upstream 100 bases:
>100_bases TATGTTTCATTTTATTCGACAGAAACGCCTGGATCGGGTATAATGTGAGATGGCAAACATCGCATAATAATGCGCTAAAA CCGACGTAACGGAGTAACAA
Downstream 100 bases:
>100_bases GGGGCAGGGGACAAAATACTGGAATCAAATCTGGTGTCATCGTGGTCGTAGCGGATTATCCACCGATCACGCCGACACCG CTCCTGGGCGCGGCGGCGCA
Product: DNA gyrase subunit A
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 822; Mature: 822
Protein sequence:
>822_residues MEIGIVRPVNITNEMRTAYLSYAMSVIVSRALPDARDGLKPVQRRILYGMWDMGFRSNQPYKKSARIVGDVLGKMHPHGD SAVYDALARMAQPWSMRYPLIDGQGNFGSIDGDPPAAMRYTEARLAPIAEELLSEIEKDTVDFRDNFDGSYREPVVLPAI LPNLLLNGASGIAVGMATNIPPHNLGELCDAISYLIEHPEATVEELMKIIPGPDFPTAGLILGTEGILAAYSTGRGQITL RAKTHIEEAGRGAFMIVVTELPYQVNKARLQERIAELVKDRKIEGIRDVRDESDRTGMRLVILLKQDAQPKKVLNALYKH TQMQTTFGINMLALVEHGRQPRVLTLKRLLQEYITHRQEVIRRRTEFDLARARERAHILEGLKIALDNLDAVIQTIRDSR TAESARNNLMSNFSLTERQAQAILDLQLRRLAALERKKIEDEYREVIKLIAELEDILANPRKVLHLIQQDLTRLKEKYGD PRRTRIIPDVTGEVSDEDLIPDVRVMITLTDRGYIKRQLPDAYRTQRRGGRGIKGMLTREQDIVRHLLTCNSLDNLLFFT DRGKVYQLKAHEVPDSSRTAKGLPLVNLISLEPGEQVTSMLAVREFDAEYLVMATVRGKIKRTQLREYSQVRSNGLIAIG LEEGDVLGWVRVSHGHEDILLTTARGQTLRFEQSEVRPMGRPATGVIGINLADGDRVVSMDLAEEGADLLVVTARGIGKR TALSEYPVKGRATGGVITIKLRNDLDEVAAAAVVREHSLLTFITTGGMVLRTSASEISRLGRATQGVTIVNVATGDRVAA LSVEDPEENGNGSTPTLIDPLS
Sequences:
>Translated_822_residues MEIGIVRPVNITNEMRTAYLSYAMSVIVSRALPDARDGLKPVQRRILYGMWDMGFRSNQPYKKSARIVGDVLGKMHPHGD SAVYDALARMAQPWSMRYPLIDGQGNFGSIDGDPPAAMRYTEARLAPIAEELLSEIEKDTVDFRDNFDGSYREPVVLPAI LPNLLLNGASGIAVGMATNIPPHNLGELCDAISYLIEHPEATVEELMKIIPGPDFPTAGLILGTEGILAAYSTGRGQITL RAKTHIEEAGRGAFMIVVTELPYQVNKARLQERIAELVKDRKIEGIRDVRDESDRTGMRLVILLKQDAQPKKVLNALYKH TQMQTTFGINMLALVEHGRQPRVLTLKRLLQEYITHRQEVIRRRTEFDLARARERAHILEGLKIALDNLDAVIQTIRDSR TAESARNNLMSNFSLTERQAQAILDLQLRRLAALERKKIEDEYREVIKLIAELEDILANPRKVLHLIQQDLTRLKEKYGD PRRTRIIPDVTGEVSDEDLIPDVRVMITLTDRGYIKRQLPDAYRTQRRGGRGIKGMLTREQDIVRHLLTCNSLDNLLFFT DRGKVYQLKAHEVPDSSRTAKGLPLVNLISLEPGEQVTSMLAVREFDAEYLVMATVRGKIKRTQLREYSQVRSNGLIAIG LEEGDVLGWVRVSHGHEDILLTTARGQTLRFEQSEVRPMGRPATGVIGINLADGDRVVSMDLAEEGADLLVVTARGIGKR TALSEYPVKGRATGGVITIKLRNDLDEVAAAAVVREHSLLTFITTGGMVLRTSASEISRLGRATQGVTIVNVATGDRVAA LSVEDPEENGNGSTPTLIDPLS >Mature_822_residues MEIGIVRPVNITNEMRTAYLSYAMSVIVSRALPDARDGLKPVQRRILYGMWDMGFRSNQPYKKSARIVGDVLGKMHPHGD SAVYDALARMAQPWSMRYPLIDGQGNFGSIDGDPPAAMRYTEARLAPIAEELLSEIEKDTVDFRDNFDGSYREPVVLPAI LPNLLLNGASGIAVGMATNIPPHNLGELCDAISYLIEHPEATVEELMKIIPGPDFPTAGLILGTEGILAAYSTGRGQITL RAKTHIEEAGRGAFMIVVTELPYQVNKARLQERIAELVKDRKIEGIRDVRDESDRTGMRLVILLKQDAQPKKVLNALYKH TQMQTTFGINMLALVEHGRQPRVLTLKRLLQEYITHRQEVIRRRTEFDLARARERAHILEGLKIALDNLDAVIQTIRDSR TAESARNNLMSNFSLTERQAQAILDLQLRRLAALERKKIEDEYREVIKLIAELEDILANPRKVLHLIQQDLTRLKEKYGD PRRTRIIPDVTGEVSDEDLIPDVRVMITLTDRGYIKRQLPDAYRTQRRGGRGIKGMLTREQDIVRHLLTCNSLDNLLFFT DRGKVYQLKAHEVPDSSRTAKGLPLVNLISLEPGEQVTSMLAVREFDAEYLVMATVRGKIKRTQLREYSQVRSNGLIAIG LEEGDVLGWVRVSHGHEDILLTTARGQTLRFEQSEVRPMGRPATGVIGINLADGDRVVSMDLAEEGADLLVVTARGIGKR TALSEYPVKGRATGGVITIKLRNDLDEVAAAAVVREHSLLTFITTGGMVLRTSASEISRLGRATQGVTIVNVATGDRVAA LSVEDPEENGNGSTPTLIDPLS
Specific function: DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings [H]
COG id: COG0188
COG function: function code L; Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the topoisomerase gyrA/parC subunit family [H]
Homologues:
Organism=Homo sapiens, GI19913408, Length=349, Percent_Identity=23.7822349570201, Blast_Score=80, Evalue=6e-15, Organism=Homo sapiens, GI19913406, Length=377, Percent_Identity=24.4031830238727, Blast_Score=78, Evalue=3e-14, Organism=Escherichia coli, GI1788562, Length=834, Percent_Identity=48.4412470023981, Blast_Score=775, Evalue=0.0, Organism=Escherichia coli, GI1789396, Length=695, Percent_Identity=38.5611510791367, Blast_Score=427, Evalue=1e-120, Organism=Caenorhabditis elegans, GI212645845, Length=362, Percent_Identity=22.6519337016575, Blast_Score=79, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17535065, Length=355, Percent_Identity=25.3521126760563, Blast_Score=76, Evalue=8e-14, Organism=Caenorhabditis elegans, GI212645657, Length=354, Percent_Identity=25.1412429378531, Blast_Score=71, Evalue=2e-12, Organism=Saccharomyces cerevisiae, GI6324241, Length=344, Percent_Identity=25, Blast_Score=84, Evalue=9e-17, Organism=Drosophila melanogaster, GI17136538, Length=354, Percent_Identity=24.8587570621469, Blast_Score=76, Evalue=1e-13,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR020899 - InterPro: IPR005743 - InterPro: IPR006691 - InterPro: IPR002205 - InterPro: IPR013758 - InterPro: IPR013757 - InterPro: IPR013760 [H]
Pfam domain/function: PF03989 DNA_gyraseA_C; PF00521 DNA_topoisoIV [H]
EC number: =5.99.1.3 [H]
Molecular weight: Translated: 91494; Mature: 91494
Theoretical pI: Translated: 7.85; Mature: 7.85
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.2 %Cys (Translated Protein) 2.8 %Met (Translated Protein) 3.0 %Cys+Met (Translated Protein) 0.2 %Cys (Mature Protein) 2.8 %Met (Mature Protein) 3.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MEIGIVRPVNITNEMRTAYLSYAMSVIVSRALPDARDGLKPVQRRILYGMWDMGFRSNQP CCCCEECCCCCHHHHHHHHHHHHHHHHHHHCCCCHHCCHHHHHHHHHHHHHCCCCCCCCC YKKSARIVGDVLGKMHPHGDSAVYDALARMAQPWSMRYPLIDGQGNFGSIDGDPPAAMRY HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCEECCCCCCCCCCCCCCHHHHH TEARLAPIAEELLSEIEKDTVDFRDNFDGSYREPVVLPAILPNLLLNGASGIAVGMATNI HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEHHHHHHHHHHCCCCCEEEEEECCC PPHNLGELCDAISYLIEHPEATVEELMKIIPGPDFPTAGLILGTEGILAAYSTGRGQITL CCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCEEECCCCCEEEEECCCCEEEE RAKTHIEEAGRGAFMIVVTELPYQVNKARLQERIAELVKDRKIEGIRDVRDESDRTGMRL EEHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCEE VILLKQDAQPKKVLNALYKHTQMQTTFGINMLALVEHGRQPRVLTLKRLLQEYITHRQEV EEEEECCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH IRRRTEFDLARARERAHILEGLKIALDNLDAVIQTIRDSRTAESARNNLMSNFSLTERQA HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH QAILDLQLRRLAALERKKIEDEYREVIKLIAELEDILANPRKVLHLIQQDLTRLKEKYGD HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCC PRRTRIIPDVTGEVSDEDLIPDVRVMITLTDRGYIKRQLPDAYRTQRRGGRGIKGMLTRE CHHEEECCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHCCHHHHHHHCCCCCCCHHHCCH QDIVRHLLTCNSLDNLLFFTDRGKVYQLKAHEVPDSSRTAKGLPLVNLISLEPGEQVTSM HHHHHHHHHHCCCCCEEEEECCCCEEEEEECCCCCCCCCCCCCCEEEEEECCCHHHHHHH LAVREFDAEYLVMATVRGKIKRTQLREYSQVRSNGLIAIGLEEGDVLGWVRVSHGHEDIL HHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCEEEEEEECCCCCCEE LTTARGQTLRFEQSEVRPMGRPATGVIGINLADGDRVVSMDLAEEGADLLVVTARGIGKR EEECCCCEEEECHHHCCCCCCCCCEEEEEEECCCCEEEEEEHHHCCCCEEEEEECCCCCC TALSEYPVKGRATGGVITIKLRNDLDEVAAAAVVREHSLLTFITTGGMVLRTSASEISRL CCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCEEEEEECCCEEEEECHHHHHHH GRATQGVTIVNVATGDRVAALSVEDPEENGNGSTPTLIDPLS CCHHCCEEEEEEECCCEEEEEEECCCCCCCCCCCCCEECCCC >Mature Secondary Structure MEIGIVRPVNITNEMRTAYLSYAMSVIVSRALPDARDGLKPVQRRILYGMWDMGFRSNQP CCCCEECCCCCHHHHHHHHHHHHHHHHHHHCCCCHHCCHHHHHHHHHHHHHCCCCCCCCC YKKSARIVGDVLGKMHPHGDSAVYDALARMAQPWSMRYPLIDGQGNFGSIDGDPPAAMRY HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCEECCCCCCCCCCCCCCHHHHH TEARLAPIAEELLSEIEKDTVDFRDNFDGSYREPVVLPAILPNLLLNGASGIAVGMATNI HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEHHHHHHHHHHCCCCCEEEEEECCC PPHNLGELCDAISYLIEHPEATVEELMKIIPGPDFPTAGLILGTEGILAAYSTGRGQITL CCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCEEECCCCCEEEEECCCCEEEE RAKTHIEEAGRGAFMIVVTELPYQVNKARLQERIAELVKDRKIEGIRDVRDESDRTGMRL EEHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCEE VILLKQDAQPKKVLNALYKHTQMQTTFGINMLALVEHGRQPRVLTLKRLLQEYITHRQEV EEEEECCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH IRRRTEFDLARARERAHILEGLKIALDNLDAVIQTIRDSRTAESARNNLMSNFSLTERQA HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH QAILDLQLRRLAALERKKIEDEYREVIKLIAELEDILANPRKVLHLIQQDLTRLKEKYGD HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCC PRRTRIIPDVTGEVSDEDLIPDVRVMITLTDRGYIKRQLPDAYRTQRRGGRGIKGMLTRE CHHEEECCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHCCHHHHHHHCCCCCCCHHHCCH QDIVRHLLTCNSLDNLLFFTDRGKVYQLKAHEVPDSSRTAKGLPLVNLISLEPGEQVTSM HHHHHHHHHHCCCCCEEEEECCCCEEEEEECCCCCCCCCCCCCCEEEEEECCCHHHHHHH LAVREFDAEYLVMATVRGKIKRTQLREYSQVRSNGLIAIGLEEGDVLGWVRVSHGHEDIL HHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCEEEEEEECCCCCCEE LTTARGQTLRFEQSEVRPMGRPATGVIGINLADGDRVVSMDLAEEGADLLVVTARGIGKR EEECCCCEEEECHHHCCCCCCCCCEEEEEEECCCCEEEEEEHHHCCCCEEEEEECCCCCC TALSEYPVKGRATGGVITIKLRNDLDEVAAAAVVREHSLLTFITTGGMVLRTSASEISRL CCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCEEEEEECCCEEEEECHHHHHHH GRATQGVTIVNVATGDRVAALSVEDPEENGNGSTPTLIDPLS CCHHCCEEEEEEECCCEEEEEEECCCCCCCCCCCCCEECCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 2987847; 7584024; 9384377 [H]