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The map label for this gene is p20 [H]

Identifier: 222524640

GI number: 222524640

Start: 1747017

End: 1747574

Strand: Reverse

Name: p20 [H]

Synonym: Chy400_1365

Alternate gene names: 222524640

Gene position: 1747574-1747017 (Counterclockwise)

Preceding gene: 222524641

Following gene: 222524636

Centisome position: 33.17

GC content: 56.45

Gene sequence:

>558_bases
ATGATCACGTCATCGCGCCCCCGCCCAAAGGTGATGACCGGCGAGAAGGTCTTTTTGAGCCACGTCTTTGCTGAAGATGC
TCCACTTTTGGCGCAATGGTTTGCCGATCTGGAATTCACCACTCTCTTGGGGCAGCAGGGGCGTAGTTTTACCCTGGAGC
AAGAACAGCAGTGGATTACAGAGAGCACAGCGGCGAAAGATAGTGAACGTTCGTTTGCGATAGTGCTGTGTGCCAATGAG
CAATTGATAGGTACGTGCAATCTGCGAAGCATCGATTTATTGCACGGCACCGCCGAGTTGGGCATTGCTATCGGCGACAA
AACGGCCTGGGGGCAGGGGTACGGTCGTGAAGCTGTCCGCTTACTCGTCGCGTATGGGTTTCGTTACCTCAACCTGTACA
GCATCAGGTTATGGGTGCATGGCTTCAACGAACGTGCCCGTCGCGCTTACCTGGCAGCCGGCTTTCGCGAGGCAGGCCGG
CTGCGCGGGGCAACGCTATTCGACGGCCAGCGCTACGACCGTATTCTCATGGAAATCACCCGCGACGATGTTCGCTGA

Upstream 100 bases:

>100_bases
CGCAGTGGAGCGGGGTGACATCACGGCAGCCCGGTACGATAGTTACGCCCGGCTGATGGAGAGTGAAGACGAGGAATAGC
AGCCTGCCCAGGAGGAAACT

Downstream 100 bases:

>100_bases
AGTGAGGCATGTAGAGCGGGCGAATCCGCTGATAGACGGCATCCCAGGTTAACTCGCGCCAGACCCGCGCTCGTCCGGCA
GCACCGAGAGCGCGGGCAAG

Product: GCN5-like N-acetyltransferase

Products: Coenzyme A; H+; N8-Acetylspermidine [C]

Alternate protein names: NA

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MITSSRPRPKVMTGEKVFLSHVFAEDAPLLAQWFADLEFTTLLGQQGRSFTLEQEQQWITESTAAKDSERSFAIVLCANE
QLIGTCNLRSIDLLHGTAELGIAIGDKTAWGQGYGREAVRLLVAYGFRYLNLYSIRLWVHGFNERARRAYLAAGFREAGR
LRGATLFDGQRYDRILMEITRDDVR

Sequences:

>Translated_185_residues
MITSSRPRPKVMTGEKVFLSHVFAEDAPLLAQWFADLEFTTLLGQQGRSFTLEQEQQWITESTAAKDSERSFAIVLCANE
QLIGTCNLRSIDLLHGTAELGIAIGDKTAWGQGYGREAVRLLVAYGFRYLNLYSIRLWVHGFNERARRAYLAAGFREAGR
LRGATLFDGQRYDRILMEITRDDVR
>Mature_185_residues
MITSSRPRPKVMTGEKVFLSHVFAEDAPLLAQWFADLEFTTLLGQQGRSFTLEQEQQWITESTAAKDSERSFAIVLCANE
QLIGTCNLRSIDLLHGTAELGIAIGDKTAWGQGYGREAVRLLVAYGFRYLNLYSIRLWVHGFNERARRAYLAAGFREAGR
LRGATLFDGQRYDRILMEITRDDVR

Specific function: Regulates Polyamine Concentration By Their Degradation. Acts On Spermidine, Forming N(1)- And N(8)-Acetylspermidine. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181 [H]

Pfam domain/function: PF00583 Acetyltransf_1 [H]

EC number: 2.3.1.57 [C]

Molecular weight: Translated: 20995; Mature: 20995

Theoretical pI: Translated: 8.21; Mature: 8.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITSSRPRPKVMTGEKVFLSHVFAEDAPLLAQWFADLEFTTLLGQQGRSFTLEQEQQWIT
CCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHCCHHHHHHCCCCCCCCCHHHHHHHH
ESTAAKDSERSFAIVLCANEQLIGTCNLRSIDLLHGTAELGIAIGDKTAWGQGYGREAVR
HHHCCCCCCCCEEEEEECCCCEEEECCCCEEEEEECHHHEEEEECCCCCCCCCCCHHHHH
LLVAYGFRYLNLYSIRLWVHGFNERARRAYLAAGFREAGRLRGATLFDGQRYDRILMEIT
HHHHHHHHHHEEEEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHH
RDDVR
HHCCC
>Mature Secondary Structure
MITSSRPRPKVMTGEKVFLSHVFAEDAPLLAQWFADLEFTTLLGQQGRSFTLEQEQQWIT
CCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHCCHHHHHHCCCCCCCCCHHHHHHHH
ESTAAKDSERSFAIVLCANEQLIGTCNLRSIDLLHGTAELGIAIGDKTAWGQGYGREAVR
HHHCCCCCCCCEEEEEECCCCEEEECCCCEEEEEECHHHEEEEECCCCCCCCCCCHHHHH
LLVAYGFRYLNLYSIRLWVHGFNERARRAYLAAGFREAGRLRGATLFDGQRYDRILMEIT
HHHHHHHHHHEEEEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHH
RDDVR
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Acetyl-CoA; Spermidine [C]

Specific reaction: Acetyl-CoA + Spermidine --> Coenzyme A + H+ + N8-Acetylspermidine [C]

General reaction: Acyl group transfer [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2838827 [H]