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The map label for this gene is selA [H]

Identifier: 222524394

GI number: 222524394

Start: 1415242

End: 1416600

Strand: Direct

Name: selA [H]

Synonym: Chy400_1118

Alternate gene names: 222524394

Gene position: 1415242-1416600 (Clockwise)

Preceding gene: 222524393

Following gene: 222524395

Centisome position: 26.86

GC content: 61.59

Gene sequence:

>1359_bases
ATGACGTTCCGCGCCTTACCCAGTGTTGATAGACTCATCCGCGCCGTCCGCAGCGACGGGGCCGATATGCCGCACGAACT
GGTGCGTGAGGCTGCCCGTGCTGTTCTCAACGAGGCGCGGACATCTATCAGTGCCGGTCATCCGCCACCCGATCTGTCTA
CGCTGGTAGCGGCTGTCCAGGCGCGCCTGCGCGCAGATGTGACACCCAGCCTGCGTCCGTTGATCAACGCCACTGGGGTC
ATCATCCAAACCAACCTCGGTCGGGCGCCGTTGAGTGCTGCGGCTTGTGCGGCGATGCAGGAAGTCGGCAGCGGTTACAG
CAATCTCGAATACGATCTGGCTCAGGGCGAACGTGGTTCGCGTCACGTTCATCTCGAATCGCTCCTCGTTCAGCTTACCG
GCGCCGAGGCAGCCCTGGTCGTGAACAACAACGCCGCTGCCGTCTATCTGGTGCTCATCGCCATGGCTGCCGGACGCGAA
GTGATTGTCTCACGTGGGCAGGCAGTAGAAATCGGTGGTGGCTTCCGCATTCCCGATGTCTTACGGGCAAGCGGCGCTCT
CCTGATCGAAGTTGGCACGACCAACCGCACCTATGCCCGTGACTATACCGCGGCCATCACCGAGCGCACCGCTCTGATCT
TGCGCGTCCACACCAGTAACTTTCGCCTGATCGGGTTCGTCCACGAACCACCTCTCGCCGAGTTAACCGCGGTTGCCCAT
ACCCATGGTATACCGCTGCTCGATGATCTGGGGAGCGGAACTCTGATTGATACCCGTCAGTTTGACCTGCCGCCTGAGCC
AACCGTGCAGGAGAGTGTTGCTGCCGGTGCCGATCTGGTGACATTTTCTGGCGATAAGCTGCTCGGTGGGCCGCAAGCCG
GTATCATCGTCGGGCGTCGTGAGCTGATCGCCAGACTGCGGCGTCACCCACTTGCCCGCGCCTTACGGGTTGATAAGTGT
ACGATTGCCGGCTTAACCGCGACCCTGCACAGTTATCTGCGTGGCACTGCCCTACGCGAGATTCCGGTCTGGCAACTGAT
CAGCACCCCGTTGAGCGCATTGCAGGCGCGCGCAGAGCGTATTGCCGGCGCCCTGCGTGCTGCCGGCATTCCGGCGCAGA
TGGTGGATTGTGCCAGTGCGATTGGTGGCGGTTCACTCCCCGGTGCAACGCAACCCAGCGCCGGTGTCGCTCTGCCCCCT
GTTGGCTGTGGGGCTACCGTGCTGGCGCACCGGCTGCGCATGGCCAATCCACCGGTGATAACCCGGATTGTTGATGATCA
GGTACTGTGCGATCTCCGTAGCGTTTTTCCACACGAAGATACCACCCTGATCAATGTCGTGCGTGAGGTCTGGCAATGA

Upstream 100 bases:

>100_bases
AATGGCACGGCGGAAACGCGAGCTGACGCCCAGTTACGAGCAGGTGCTGCGCAAGGCTTTTGAGATAACGCAACCAAGTC
GTGATGGTCTGGGATAGACA

Downstream 100 bases:

>100_bases
AAATCTACGGTCTCCTGCTGGCTGCCGGCCAATCTTCTCGTATGGGGCAACCCAAACAGCTCCTATCCTGGCGTGGTCGC
CCGTTAGTGACGTATATCGC

Product: selenocysteine synthase

Products: NA

Alternate protein names: Selenocysteine synthase; Sec synthase; Selenocysteinyl-tRNA(Sec) synthase [H]

Number of amino acids: Translated: 452; Mature: 451

Protein sequence:

>452_residues
MTFRALPSVDRLIRAVRSDGADMPHELVREAARAVLNEARTSISAGHPPPDLSTLVAAVQARLRADVTPSLRPLINATGV
IIQTNLGRAPLSAAACAAMQEVGSGYSNLEYDLAQGERGSRHVHLESLLVQLTGAEAALVVNNNAAAVYLVLIAMAAGRE
VIVSRGQAVEIGGGFRIPDVLRASGALLIEVGTTNRTYARDYTAAITERTALILRVHTSNFRLIGFVHEPPLAELTAVAH
THGIPLLDDLGSGTLIDTRQFDLPPEPTVQESVAAGADLVTFSGDKLLGGPQAGIIVGRRELIARLRRHPLARALRVDKC
TIAGLTATLHSYLRGTALREIPVWQLISTPLSALQARAERIAGALRAAGIPAQMVDCASAIGGGSLPGATQPSAGVALPP
VGCGATVLAHRLRMANPPVITRIVDDQVLCDLRSVFPHEDTTLINVVREVWQ

Sequences:

>Translated_452_residues
MTFRALPSVDRLIRAVRSDGADMPHELVREAARAVLNEARTSISAGHPPPDLSTLVAAVQARLRADVTPSLRPLINATGV
IIQTNLGRAPLSAAACAAMQEVGSGYSNLEYDLAQGERGSRHVHLESLLVQLTGAEAALVVNNNAAAVYLVLIAMAAGRE
VIVSRGQAVEIGGGFRIPDVLRASGALLIEVGTTNRTYARDYTAAITERTALILRVHTSNFRLIGFVHEPPLAELTAVAH
THGIPLLDDLGSGTLIDTRQFDLPPEPTVQESVAAGADLVTFSGDKLLGGPQAGIIVGRRELIARLRRHPLARALRVDKC
TIAGLTATLHSYLRGTALREIPVWQLISTPLSALQARAERIAGALRAAGIPAQMVDCASAIGGGSLPGATQPSAGVALPP
VGCGATVLAHRLRMANPPVITRIVDDQVLCDLRSVFPHEDTTLINVVREVWQ
>Mature_451_residues
TFRALPSVDRLIRAVRSDGADMPHELVREAARAVLNEARTSISAGHPPPDLSTLVAAVQARLRADVTPSLRPLINATGVI
IQTNLGRAPLSAAACAAMQEVGSGYSNLEYDLAQGERGSRHVHLESLLVQLTGAEAALVVNNNAAAVYLVLIAMAAGREV
IVSRGQAVEIGGGFRIPDVLRASGALLIEVGTTNRTYARDYTAAITERTALILRVHTSNFRLIGFVHEPPLAELTAVAHT
HGIPLLDDLGSGTLIDTRQFDLPPEPTVQESVAAGADLVTFSGDKLLGGPQAGIIVGRRELIARLRRHPLARALRVDKCT
IAGLTATLHSYLRGTALREIPVWQLISTPLSALQARAERIAGALRAAGIPAQMVDCASAIGGGSLPGATQPSAGVALPPV
GCGATVLAHRLRMANPPVITRIVDDQVLCDLRSVFPHEDTTLINVVREVWQ

Specific function: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis [H]

COG id: COG1921

COG function: function code E; Selenocysteine synthase [seryl-tRNASer selenium transferase]

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the selA family [H]

Homologues:

Organism=Escherichia coli, GI2367248, Length=443, Percent_Identity=47.4040632054176, Blast_Score=333, Evalue=1e-92,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR018319
- InterPro:   IPR004534 [H]

Pfam domain/function: PF03841 SelA [H]

EC number: =2.9.1.1 [H]

Molecular weight: Translated: 47764; Mature: 47632

Theoretical pI: Translated: 7.98; Mature: 7.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFRALPSVDRLIRAVRSDGADMPHELVREAARAVLNEARTSISAGHPPPDLSTLVAAVQ
CCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
ARLRADVTPSLRPLINATGVIIQTNLGRAPLSAAACAAMQEVGSGYSNLEYDLAQGERGS
HHHHCCCCCCHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCCEEEHHCCCCCC
RHVHLESLLVQLTGAEAALVVNNNAAAVYLVLIAMAAGREVIVSRGQAVEIGGGFRIPDV
CEEEHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHCCCHHHHCCCCEEEECCCCCCHHH
LRASGALLIEVGTTNRTYARDYTAAITERTALILRVHTSNFRLIGFVHEPPLAELTAVAH
HHCCCCEEEEECCCCCCCHHHHHHHHHHCEEEEEEEECCCEEEEEEECCCCHHHHHHHHH
THGIPLLDDLGSGTLIDTRQFDLPPEPTVQESVAAGADLVTFSGDKLLGGPQAGIIVGRR
HCCCCCHHHCCCCCEEECCCCCCCCCCCHHHHHHCCCCEEEECCCCCCCCCCCCEEECHH
ELIARLRRHPLARALRVDKCTIAGLTATLHSYLRGTALREIPVWQLISTPLSALQARAER
HHHHHHHHCHHHHHHHHCHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHH
IAGALRAAGIPAQMVDCASAIGGGSLPGATQPSAGVALPPVGCGATVLAHRLRMANPPVI
HHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEE
TRIVDDQVLCDLRSVFPHEDTTLINVVREVWQ
EEECCHHHHHHHHHHCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
TFRALPSVDRLIRAVRSDGADMPHELVREAARAVLNEARTSISAGHPPPDLSTLVAAVQ
CCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
ARLRADVTPSLRPLINATGVIIQTNLGRAPLSAAACAAMQEVGSGYSNLEYDLAQGERGS
HHHHCCCCCCHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCCEEEHHCCCCCC
RHVHLESLLVQLTGAEAALVVNNNAAAVYLVLIAMAAGREVIVSRGQAVEIGGGFRIPDV
CEEEHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHCCCHHHHCCCCEEEECCCCCCHHH
LRASGALLIEVGTTNRTYARDYTAAITERTALILRVHTSNFRLIGFVHEPPLAELTAVAH
HHCCCCEEEEECCCCCCCHHHHHHHHHHCEEEEEEEECCCEEEEEEECCCCHHHHHHHHH
THGIPLLDDLGSGTLIDTRQFDLPPEPTVQESVAAGADLVTFSGDKLLGGPQAGIIVGRR
HCCCCCHHHCCCCCEEECCCCCCCCCCCHHHHHHCCCCEEEECCCCCCCCCCCCEEECHH
ELIARLRRHPLARALRVDKCTIAGLTATLHSYLRGTALREIPVWQLISTPLSALQARAER
HHHHHHHHCHHHHHHHHCHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHH
IAGALRAAGIPAQMVDCASAIGGGSLPGATQPSAGVALPPVGCGATVLAHRLRMANPPVI
HHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEE
TRIVDDQVLCDLRSVFPHEDTTLINVVREVWQ
EEECCHHHHHHHHHHCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA