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The map label for this gene is sucD [H]

Identifier: 222524042

GI number: 222524042

Start: 946393

End: 947280

Strand: Direct

Name: sucD [H]

Synonym: Chy400_0757

Alternate gene names: 222524042

Gene position: 946393-947280 (Clockwise)

Preceding gene: 222524041

Following gene: 222524045

Centisome position: 17.96

GC content: 58.56

Gene sequence:

>888_bases
GTGAGCATTCTGATCGATGCCAACACCCGACTGTTGGTACAGGGAATTACCGGTAAAGAGGGTGAATTTCACACCCGCCA
GATGATCGAGTATGGGACAAATGTCGTTGCCGGCGTCGTCCCCGGACGTGGTGGTCAGAAGGCGATTGATGGCCGAGTGC
CTGTCTTCAATACAGTAGCGGAAGCAGTCGCTGCAACCGGCGCCAACACTGCGGTTATCTATGTGCCTGCACCCTTTGCG
CCCGATGCCATTCGCGAGTCGGCAGCCGCCCGTATTCCGCTCATCGTGTGTATTACCGAGGGCATCCCGGCACTCGATAT
GGTCAGTACCTACGCCTTTGTGCAAGAGTGCGGCGTGCGCCTGATCGGGCCGAACTGTCCCGGCTTGCTTACGCCAGGAG
CAGCCAAAGTGGGCATCATTCCCGGTAACATCGCGATGCCCGGCCCGGTTGGGATCGTGAGCAAATCGGGTACCCTGACC
TATGAAGCGGTTGATGCGCTCACCCGGCTGGGCATTGGGCAGAGCACTATCGTCGGCATTGGCGGCGATCCGATTATCGG
GACAAATTTCATTGATGTATTAAGCATGTTTGAGGCTGATCCACAAACTGAGGCGATTGTTCTGATTGGCGAAATTGGTG
GTACCGCCGAACAAGAGGCCGCCGCTTACATTAAGGCCCATGTGACGAAGCCAGTGGTAGGCTTCATTGCGGGCCAGACA
GCGCCGCCCGGTAAACGCATGGGACACGCCGGTGCGATCATCAGCGGTGGCGAAGGAACCGCCCAGGAAAAGATCGCCGC
GCTGGAAAGTGTTGGGGTGCGCGTTGCCCGGATGCCAACCGATATTGCCGGCCTGGTTAAAGAGGCGCTTAGCGCCCGTG
CCGGGTAG

Upstream 100 bases:

>100_bases
GCAGGAGGCTGAAGGCACAAACCTTGAACCGCGAAATAGCGACACGTATTAAGATAAAGCATATCGCATCGTATATCTGT
ACTTTATTAAGGAGGAACGA

Downstream 100 bases:

>100_bases
GCTGGGTGATAGTAGTACGACGCACGGGAAGAGGGTGGGTTAGAAATCCACCCTCTTCATCTTTGATCGGCCAGATAATT
GTGATCAGCAAGGGTGAGCG

Product: succinyl-CoA synthetase subunit alpha

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit alpha; SCS-alpha [H]

Number of amino acids: Translated: 295; Mature: 294

Protein sequence:

>295_residues
MSILIDANTRLLVQGITGKEGEFHTRQMIEYGTNVVAGVVPGRGGQKAIDGRVPVFNTVAEAVAATGANTAVIYVPAPFA
PDAIRESAAARIPLIVCITEGIPALDMVSTYAFVQECGVRLIGPNCPGLLTPGAAKVGIIPGNIAMPGPVGIVSKSGTLT
YEAVDALTRLGIGQSTIVGIGGDPIIGTNFIDVLSMFEADPQTEAIVLIGEIGGTAEQEAAAYIKAHVTKPVVGFIAGQT
APPGKRMGHAGAIISGGEGTAQEKIAALESVGVRVARMPTDIAGLVKEALSARAG

Sequences:

>Translated_295_residues
MSILIDANTRLLVQGITGKEGEFHTRQMIEYGTNVVAGVVPGRGGQKAIDGRVPVFNTVAEAVAATGANTAVIYVPAPFA
PDAIRESAAARIPLIVCITEGIPALDMVSTYAFVQECGVRLIGPNCPGLLTPGAAKVGIIPGNIAMPGPVGIVSKSGTLT
YEAVDALTRLGIGQSTIVGIGGDPIIGTNFIDVLSMFEADPQTEAIVLIGEIGGTAEQEAAAYIKAHVTKPVVGFIAGQT
APPGKRMGHAGAIISGGEGTAQEKIAALESVGVRVARMPTDIAGLVKEALSARAG
>Mature_294_residues
SILIDANTRLLVQGITGKEGEFHTRQMIEYGTNVVAGVVPGRGGQKAIDGRVPVFNTVAEAVAATGANTAVIYVPAPFAP
DAIRESAAARIPLIVCITEGIPALDMVSTYAFVQECGVRLIGPNCPGLLTPGAAKVGIIPGNIAMPGPVGIVSKSGTLTY
EAVDALTRLGIGQSTIVGIGGDPIIGTNFIDVLSMFEADPQTEAIVLIGEIGGTAEQEAAAYIKAHVTKPVVGFIAGQTA
PPGKRMGHAGAIISGGEGTAQEKIAALESVGVRVARMPTDIAGLVKEALSARAG

Specific function: Unknown

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinate/malate CoA ligase alpha subunit family [H]

Homologues:

Organism=Homo sapiens, GI109452591, Length=296, Percent_Identity=55.4054054054054, Blast_Score=273, Evalue=1e-73,
Organism=Homo sapiens, GI38569423, Length=274, Percent_Identity=31.021897810219, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI38569421, Length=274, Percent_Identity=31.021897810219, Blast_Score=92, Evalue=5e-19,
Organism=Escherichia coli, GI1786949, Length=291, Percent_Identity=65.2920962199313, Blast_Score=373, Evalue=1e-105,
Organism=Escherichia coli, GI1786513, Length=148, Percent_Identity=31.0810810810811, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17550194, Length=286, Percent_Identity=55.2447552447552, Blast_Score=290, Evalue=6e-79,
Organism=Caenorhabditis elegans, GI17553126, Length=294, Percent_Identity=52.7210884353742, Blast_Score=278, Evalue=2e-75,
Organism=Caenorhabditis elegans, GI17557344, Length=311, Percent_Identity=26.6881028938907, Blast_Score=91, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17551266, Length=275, Percent_Identity=28.3636363636364, Blast_Score=87, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6324716, Length=287, Percent_Identity=46.6898954703833, Blast_Score=241, Evalue=8e-65,
Organism=Drosophila melanogaster, GI21356559, Length=295, Percent_Identity=52.2033898305085, Blast_Score=289, Evalue=2e-78,
Organism=Drosophila melanogaster, GI28574296, Length=293, Percent_Identity=53.2423208191126, Blast_Score=272, Evalue=2e-73,
Organism=Drosophila melanogaster, GI281363477, Length=262, Percent_Identity=30.1526717557252, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI281363475, Length=262, Percent_Identity=30.1526717557252, Blast_Score=91, Evalue=7e-19,
Organism=Drosophila melanogaster, GI281363473, Length=262, Percent_Identity=30.1526717557252, Blast_Score=91, Evalue=7e-19,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017440
- InterPro:   IPR003781
- InterPro:   IPR005810
- InterPro:   IPR005811
- InterPro:   IPR016040
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 29943; Mature: 29812

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: PS01216 SUCCINYL_COA_LIG_1 ; PS00399 SUCCINYL_COA_LIG_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSILIDANTRLLVQGITGKEGEFHTRQMIEYGTNVVAGVVPGRGGQKAIDGRVPVFNTVA
CEEEEECCCEEEEEECCCCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCHHHHHH
EAVAATGANTAVIYVPAPFAPDAIRESAAARIPLIVCITEGIPALDMVSTYAFVQECGVR
HHHHHCCCCEEEEEECCCCCHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHCCCE
LIGPNCPGLLTPGAAKVGIIPGNIAMPGPVGIVSKSGTLTYEAVDALTRLGIGQSTIVGI
EECCCCCCCCCCCCCEEEEECCCCCCCCCCEEEECCCCEEHHHHHHHHHCCCCCCEEEEC
GGDPIIGTNFIDVLSMFEADPQTEAIVLIGEIGGTAEQEAAAYIKAHVTKPVVGFIAGQT
CCCCCCCCHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCHHHHHHHCCCC
APPGKRMGHAGAIISGGEGTAQEKIAALESVGVRVARMPTDIAGLVKEALSARAG
CCCCCCCCCCCCEEECCCCCHHHHHHHHHHHCEEEEECCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SILIDANTRLLVQGITGKEGEFHTRQMIEYGTNVVAGVVPGRGGQKAIDGRVPVFNTVA
EEEEECCCEEEEEECCCCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCHHHHHH
EAVAATGANTAVIYVPAPFAPDAIRESAAARIPLIVCITEGIPALDMVSTYAFVQECGVR
HHHHHCCCCEEEEEECCCCCHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHCCCE
LIGPNCPGLLTPGAAKVGIIPGNIAMPGPVGIVSKSGTLTYEAVDALTRLGIGQSTIVGI
EECCCCCCCCCCCCCEEEEECCCCCCCCCCEEEECCCCEEHHHHHHHHHCCCCCCEEEEC
GGDPIIGTNFIDVLSMFEADPQTEAIVLIGEIGGTAEQEAAAYIKAHVTKPVVGFIAGQT
CCCCCCCCHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCHHHHHHHCCCC
APPGKRMGHAGAIISGGEGTAQEKIAALESVGVRVARMPTDIAGLVKEALSARAG
CCCCCCCCCCCCEEECCCCCHHHHHHHHHHHCEEEEECCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]