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The map label for this gene is gpmA2 [H]

Identifier: 222523968

GI number: 222523968

Start: 848039

End: 848680

Strand: Direct

Name: gpmA2 [H]

Synonym: Chy400_0683

Alternate gene names: 222523968

Gene position: 848039-848680 (Clockwise)

Preceding gene: 222523965

Following gene: 222523970

Centisome position: 16.1

GC content: 57.17

Gene sequence:

>642_bases
ATGCGACTGATCATTGTTCGCCACGGCGAGAGTGAATGGAACCGGATCAACCGTTATCAGGGCCAGCAGGACGCGCCACT
CTCTGAATTGGGGCGCAAGCAGGCAGCAGCGTTGGGTGAGCGTTTACGACACGAAAAGATTGACGTTGTGTATAGCAGCC
GCCTGCAACGCGCAGCCCACACTGCGCAGGCGATTGTAGCCCACCATCCCGGTCTTGAGATCATCTACGACGACGCGCTG
CTTGAGATCAACCACGGAGAATGGGAAGGGAAGTATCTGCACGAGATTCTGGAGCGTTACGCCGATGGTCTGCGCGAATG
GCGGCAGCATCCCACCCGTTCGCAGATGCCGGGTGGCGAGAGCTTCTCGAACGTACTCAAGCGGGTACTCGACTTCCGCG
AGCGGATTTGTGTCCAACACGCCGGACAGACGGTCTTGATCAGTACCCACGATGTCATCGTTAAGATTCTGGTTGCCGAT
GCTCTGGGAATGAATATGGATCGCATCAATCGCATCTGGGTTACCAACGCCAGCATCAGCGTGATTGAATACGGTGATGA
TCTGCCCTACCTGGTGAGCCTGAGCGAGGCGTGCCATCTCGGTCATTTGGCCACCACCCGTGAACAGCAGCACGCGCTGT
AG

Upstream 100 bases:

>100_bases
CCTCGTTCAGACAGCGACTATCCTCAGCCGCGAATGATACCATCTCGGCTATAATGGCGCTTGCAAAAACTACTTCTTCC
ACAGTGAGGTAATGAAGCGT

Downstream 100 bases:

>100_bases
GCACGTGCAGAGGATACTGGGGAGCAACCTCAAAGACTGACTCCACATGCGAGGTAGCGGCCATATTTCCGGCAGCCCGA
CCCTGATCTGTCGGACACCG

Product: phosphoglycerate mutase

Products: NA

Alternate protein names: BPG-dependent PGAM 2; PGAM 2; Phosphoglyceromutase 2; dPGM 2 [H]

Number of amino acids: Translated: 213; Mature: 213

Protein sequence:

>213_residues
MRLIIVRHGESEWNRINRYQGQQDAPLSELGRKQAAALGERLRHEKIDVVYSSRLQRAAHTAQAIVAHHPGLEIIYDDAL
LEINHGEWEGKYLHEILERYADGLREWRQHPTRSQMPGGESFSNVLKRVLDFRERICVQHAGQTVLISTHDVIVKILVAD
ALGMNMDRINRIWVTNASISVIEYGDDLPYLVSLSEACHLGHLATTREQQHAL

Sequences:

>Translated_213_residues
MRLIIVRHGESEWNRINRYQGQQDAPLSELGRKQAAALGERLRHEKIDVVYSSRLQRAAHTAQAIVAHHPGLEIIYDDAL
LEINHGEWEGKYLHEILERYADGLREWRQHPTRSQMPGGESFSNVLKRVLDFRERICVQHAGQTVLISTHDVIVKILVAD
ALGMNMDRINRIWVTNASISVIEYGDDLPYLVSLSEACHLGHLATTREQQHAL
>Mature_213_residues
MRLIIVRHGESEWNRINRYQGQQDAPLSELGRKQAAALGERLRHEKIDVVYSSRLQRAAHTAQAIVAHHPGLEIIYDDAL
LEINHGEWEGKYLHEILERYADGLREWRQHPTRSQMPGGESFSNVLKRVLDFRERICVQHAGQTVLISTHDVIVKILVAD
ALGMNMDRINRIWVTNASISVIEYGDDLPYLVSLSEACHLGHLATTREQQHAL

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate [H]

COG id: COG0406

COG function: function code G; Fructose-2,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily [H]

Homologues:

Organism=Homo sapiens, GI9966849, Length=139, Percent_Identity=39.568345323741, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI1790856, Length=188, Percent_Identity=31.3829787234043, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI1786857, Length=195, Percent_Identity=27.1794871794872, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1786970, Length=218, Percent_Identity=26.1467889908257, Blast_Score=69, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI25145314, Length=160, Percent_Identity=31.25, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6322697, Length=218, Percent_Identity=26.605504587156, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR005952 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =5.4.2.1 [H]

Molecular weight: Translated: 24350; Mature: 24350

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: PS00175 PG_MUTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLIIVRHGESEWNRINRYQGQQDAPLSELGRKQAAALGERLRHEKIDVVYSSRLQRAAH
CEEEEEECCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TAQAIVAHHPGLEIIYDDALLEINHGEWEGKYLHEILERYADGLREWRQHPTRSQMPGGE
HHHHHHHCCCCCEEEECCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
SFSNVLKRVLDFRERICVQHAGQTVLISTHDVIVKILVADALGMNMDRINRIWVTNASIS
HHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHCCCHHHCCEEEEECCEEE
VIEYGDDLPYLVSLSEACHLGHLATTREQQHAL
EEEECCCCHHHHHHHHHHHHHHHHHCCHHHHCC
>Mature Secondary Structure
MRLIIVRHGESEWNRINRYQGQQDAPLSELGRKQAAALGERLRHEKIDVVYSSRLQRAAH
CEEEEEECCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TAQAIVAHHPGLEIIYDDALLEINHGEWEGKYLHEILERYADGLREWRQHPTRSQMPGGE
HHHHHHHCCCCCEEEECCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
SFSNVLKRVLDFRERICVQHAGQTVLISTHDVIVKILVADALGMNMDRINRIWVTNASIS
HHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHCCCHHHCCEEEEECCEEE
VIEYGDDLPYLVSLSEACHLGHLATTREQQHAL
EEEECCCCHHHHHHHHHHHHHHHHHCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14621292 [H]