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The map label for this gene is pyrH [H]

Identifier: 222151091

GI number: 222151091

Start: 918794

End: 919516

Strand: Direct

Name: pyrH [H]

Synonym: MCCL_0842

Alternate gene names: 222151091

Gene position: 918794-919516 (Clockwise)

Preceding gene: 222151090

Following gene: 222151092

Centisome position: 43.7

GC content: 41.49

Gene sequence:

>723_bases
ATGATTGAAACTTCTAAATATAAACGTGTCGTATTAAAGTTAAGTGGAGAAGCGCTTGCCGGAGAAACAGGCTTTGGCAT
TAATCCGTTTGTGATTAAAAGTGTAGCGAAACAAGTGGCTGAAGTAGCAAAGATGGATTGCGAGATTGCTGTAATCGTAG
GCGGGGGTAACATTTGGCGCGGTAAAACGGGAAGTGACCTAGGTATGGACCGTGGTACTGCTGACTATATGGGGATGCTT
GCTACGGTAATGAATTCATTAGCATTACAGGACTCTTTAGAACAATTGGATTGTGACACGCGTGTGCTAACTTCAATTGA
GATGAAGCAAGTTGCAGAACCTTACATTCGACGTCGAGCGATACGCCATCTTGAGAAAGGTCGAGTTGTCATCTTTGCTG
CTGGTATTGGAAATCCTTATTTCTCAACAGATACGACAGCTGCATTACGTGCTGCGGAGATGGAAGCAGATGTCATCCTT
ATGGGTAAGAATAACGTAGACGGTGTATATTCAGCGGATCCGAAACTTGATCCAAATGCGAAGAAATATGAAACATTAAC
ATATATTGAAATGTTACAGGAAGGGCTGCAGGTAATGGATTCAACAGCAAGCTCATTCTGTATGGACAATGATATTCCAC
TCGTGGTATTCTCAATTATGGAAGATGGTAATATTAAACGTGCTATTATGGGTGAAGAGATAGGTACTACCATCACAAAA
TAA

Upstream 100 bases:

>100_bases
GTTAGAAAAACTACATATAATGATTTATTTAACAGAAGATTATTGATATAATGGCTATAGTTTTGTGTACAATACACATA
TTTTGAGAGGACGGGTAATA

Downstream 100 bases:

>100_bases
AATTTAGAATCAAAGGAGAAAAAGAATGACAACTGAAATTATGAATGAATTAAAATCAAAGATGGAAAAGAGTATCGAGA
GCTTACAGCGTGACTTTGCT

Product: uridylate kinase

Products: NA

Alternate protein names: UK; Uridine monophosphate kinase; UMP kinase; UMPK [H]

Number of amino acids: Translated: 240; Mature: 240

Protein sequence:

>240_residues
MIETSKYKRVVLKLSGEALAGETGFGINPFVIKSVAKQVAEVAKMDCEIAVIVGGGNIWRGKTGSDLGMDRGTADYMGML
ATVMNSLALQDSLEQLDCDTRVLTSIEMKQVAEPYIRRRAIRHLEKGRVVIFAAGIGNPYFSTDTTAALRAAEMEADVIL
MGKNNVDGVYSADPKLDPNAKKYETLTYIEMLQEGLQVMDSTASSFCMDNDIPLVVFSIMEDGNIKRAIMGEEIGTTITK

Sequences:

>Translated_240_residues
MIETSKYKRVVLKLSGEALAGETGFGINPFVIKSVAKQVAEVAKMDCEIAVIVGGGNIWRGKTGSDLGMDRGTADYMGML
ATVMNSLALQDSLEQLDCDTRVLTSIEMKQVAEPYIRRRAIRHLEKGRVVIFAAGIGNPYFSTDTTAALRAAEMEADVIL
MGKNNVDGVYSADPKLDPNAKKYETLTYIEMLQEGLQVMDSTASSFCMDNDIPLVVFSIMEDGNIKRAIMGEEIGTTITK
>Mature_240_residues
MIETSKYKRVVLKLSGEALAGETGFGINPFVIKSVAKQVAEVAKMDCEIAVIVGGGNIWRGKTGSDLGMDRGTADYMGML
ATVMNSLALQDSLEQLDCDTRVLTSIEMKQVAEPYIRRRAIRHLEKGRVVIFAAGIGNPYFSTDTTAALRAAEMEADVIL
MGKNNVDGVYSADPKLDPNAKKYETLTYIEMLQEGLQVMDSTASSFCMDNDIPLVVFSIMEDGNIKRAIMGEEIGTTITK

Specific function: Catalyzes the reversible phosphorylation of UMP to UDP [H]

COG id: COG0528

COG function: function code F; Uridylate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UMP kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786367, Length=234, Percent_Identity=44.8717948717949, Blast_Score=218, Evalue=4e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001048
- InterPro:   IPR011817
- InterPro:   IPR015963 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.4.22 [H]

Molecular weight: Translated: 26151; Mature: 26151

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
5.8 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
5.8 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIETSKYKRVVLKLSGEALAGETGFGINPFVIKSVAKQVAEVAKMDCEIAVIVGGGNIWR
CCCCHHHHEEEEEECCCEECCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCEEEC
GKTGSDLGMDRGTADYMGMLATVMNSLALQDSLEQLDCDTRVLTSIEMKQVAEPYIRRRA
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
IRHLEKGRVVIFAAGIGNPYFSTDTTAALRAAEMEADVILMGKNNVDGVYSADPKLDPNA
HHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCEEECCCCCCCCC
KKYETLTYIEMLQEGLQVMDSTASSFCMDNDIPLVVFSIMEDGNIKRAIMGEEIGTTITK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCEEEHHHCHHHHHCCCC
>Mature Secondary Structure
MIETSKYKRVVLKLSGEALAGETGFGINPFVIKSVAKQVAEVAKMDCEIAVIVGGGNIWR
CCCCHHHHEEEEEECCCEECCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCEEEC
GKTGSDLGMDRGTADYMGMLATVMNSLALQDSLEQLDCDTRVLTSIEMKQVAEPYIRRRA
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
IRHLEKGRVVIFAAGIGNPYFSTDTTAALRAAEMEADVILMGKNNVDGVYSADPKLDPNA
HHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCEEECCCCCCCCC
KKYETLTYIEMLQEGLQVMDSTASSFCMDNDIPLVVFSIMEDGNIKRAIMGEEIGTTITK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCEEEHHHCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA