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The map label for this gene is frr

Identifier: 222151092

GI number: 222151092

Start: 919542

End: 920099

Strand: Direct

Name: frr

Synonym: MCCL_0843

Alternate gene names: 222151092

Gene position: 919542-920099 (Clockwise)

Preceding gene: 222151091

Following gene: 222151093

Centisome position: 43.74

GC content: 35.13

Gene sequence:

>558_bases
ATGACAACTGAAATTATGAATGAATTAAAATCAAAGATGGAAAAGAGTATCGAGAGCTTACAGCGTGACTTTGCTGCAAT
TCGTGCGGGCCATGCAAATGCTAATCTATTAGATCGTGTATCTGTAGTTTATTACGGTGCTGAAACACCAGTTCAGCAAT
TAGCAGGTATATCAGTTCCTGAACCAAGAATGCTGTTAGTTACACCTTATGATAAAACATCGATTGATGATATTTTAAAG
GCAATTAATATGGCAAACCTCGGTGTTAACCCAACTTCAGACGGAAATGTAATCCGTATTACAGTGCCAGCTTTAACAGA
AGAACGCCGTAAAGAACTTGTTAAAGAAGCTAAGAAAGAAGCTGAGAATTCAAAGATTGCGATTCGTAATATTCGTCGCG
ATGCAAACGATGCACTTAAGAAAGCTGAAAAAGCAGGAGATATTACTGAAGATGATTTAAAATCATTTTCTGATGATGTT
CAAGCCGAAACTGATAAATTTATTAAGAAGATTGATGAATTAACTGCTTCTAAAGAAAAAGATATTTTAGAAGTATAG

Upstream 100 bases:

>100_bases
TTCTCAATTATGGAAGATGGTAATATTAAACGTGCTATTATGGGTGAAGAGATAGGTACTACCATCACAAAATAAAATTT
AGAATCAAAGGAGAAAAAGA

Downstream 100 bases:

>100_bases
TATAGTTGTAATAAAATAAATTATAGTTTTAATAAATGGCGAGCCAAATCATTTTTTGGCTCGACCTTTTTTTGTGATTT
TCATGAATATACATATATCT

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor

Number of amino acids: Translated: 185; Mature: 184

Protein sequence:

>185_residues
MTTEIMNELKSKMEKSIESLQRDFAAIRAGHANANLLDRVSVVYYGAETPVQQLAGISVPEPRMLLVTPYDKTSIDDILK
AINMANLGVNPTSDGNVIRITVPALTEERRKELVKEAKKEAENSKIAIRNIRRDANDALKKAEKAGDITEDDLKSFSDDV
QAETDKFIKKIDELTASKEKDILEV

Sequences:

>Translated_185_residues
MTTEIMNELKSKMEKSIESLQRDFAAIRAGHANANLLDRVSVVYYGAETPVQQLAGISVPEPRMLLVTPYDKTSIDDILK
AINMANLGVNPTSDGNVIRITVPALTEERRKELVKEAKKEAENSKIAIRNIRRDANDALKKAEKAGDITEDDLKSFSDDV
QAETDKFIKKIDELTASKEKDILEV
>Mature_184_residues
TTEIMNELKSKMEKSIESLQRDFAAIRAGHANANLLDRVSVVYYGAETPVQQLAGISVPEPRMLLVTPYDKTSIDDILKA
INMANLGVNPTSDGNVIRITVPALTEERRKELVKEAKKEAENSKIAIRNIRRDANDALKKAEKAGDITEDDLKSFSDDVQ
AETDKFIKKIDELTASKEKDILEV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family

Homologues:

Organism=Homo sapiens, GI20270317, Length=180, Percent_Identity=26.6666666666667, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI291042689, Length=164, Percent_Identity=28.0487804878049, Blast_Score=69, Evalue=3e-12,
Organism=Escherichia coli, GI1786368, Length=184, Percent_Identity=41.8478260869565, Blast_Score=150, Evalue=7e-38,
Organism=Drosophila melanogaster, GI24661488, Length=184, Percent_Identity=32.6086956521739, Blast_Score=90, Evalue=1e-18,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): RRF_MACCJ (B9EBD9)

Other databases:

- EMBL:   AP009484
- RefSeq:   YP_002560246.1
- GeneID:   7389866
- GenomeReviews:   AP009484_GR
- KEGG:   mcl:MCCL_0843
- OMA:   YYGAETP
- GO:   GO:0005737
- HAMAP:   MF_00040
- InterPro:   IPR002661
- InterPro:   IPR015998
- PANTHER:   PTHR20982
- PANTHER:   PTHR20982:SF3
- TIGRFAMs:   TIGR00496

Pfam domain/function: PF01765 RRF; SSF55194 Ribosome_recyc_fac

EC number: NA

Molecular weight: Translated: 20602; Mature: 20470

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTEIMNELKSKMEKSIESLQRDFAAIRAGHANANLLDRVSVVYYGAETPVQQLAGISVP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHEEECCCCHHHHHCCCCCC
EPRMLLVTPYDKTSIDDILKAINMANLGVNPTSDGNVIRITVPALTEERRKELVKEAKKE
CCCEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHH
AENSKIAIRNIRRDANDALKKAEKAGDITEDDLKSFSDDVQAETDKFIKKIDELTASKEK
HCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DILEV
HHCCC
>Mature Secondary Structure 
TTEIMNELKSKMEKSIESLQRDFAAIRAGHANANLLDRVSVVYYGAETPVQQLAGISVP
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHEEECCCCHHHHHCCCCCC
EPRMLLVTPYDKTSIDDILKAINMANLGVNPTSDGNVIRITVPALTEERRKELVKEAKKE
CCCEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHH
AENSKIAIRNIRRDANDALKKAEKAGDITEDDLKSFSDDVQAETDKFIKKIDELTASKEK
HCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DILEV
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA