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The map label for this gene is rnhB

Identifier: 222151079

GI number: 222151079

Start: 905375

End: 906169

Strand: Direct

Name: rnhB

Synonym: MCCL_0830

Alternate gene names: 222151079

Gene position: 905375-906169 (Clockwise)

Preceding gene: 222151078

Following gene: 222151080

Centisome position: 43.07

GC content: 38.74

Gene sequence:

>795_bases
ATGAAGAGTAATGACTACACAATCGCTTCACTTAAAGAAAAGGTAAGAGAGATGAATCAAGCAGAACTTATTGATTTTTT
TGAAGAAGAGTCGAGAAGTGGCGCGTTAAAAGTGAAGCAGGCGAGAGTAAAACAAATAGCGCAGGAAACTCAAGCGATAC
ACGAATATGAACAAATGCTCGAATATGAACGTCGCTATAACGGGAAAGTCGTTTGTGGTATTGATGAGGTTGGACGTGGT
CCATTAGCGGGTCCAGTTATCGCATGTGCTGTCATCTTAAACGATGGCCATCACTATATTGGGTTAAATGATTCGAAGCA
GTTATCAAAGCACAAGAGGGCATCACTTTATGACGCATTAACACAGTCGGTTACATATGCGATAGGTGCAGCAAGTGTGG
AGGAAATTGATAAATTTAATATATATGAAGCAACGAAACTTGCGATGCATAGAGCGATAGATAAGTTACCTGTAAAGCCT
GACGTACTACTGATAGATGCGATGAATCTGAATACAGGTTTAATTGAAGAATCAATCATTAAAGGTGATGCTAAAAGTGT
TTCTATCGCTGCAGCAAGTGTGATTGCGAAAGTTTATCGCGATCACCTGATGGAAGAGATTCATGAGGAATTTCCTTACT
ATGATTTTAATCGTAATGCTGGATATGGTACTAAAAGACATTTAGATGGTTTAATGCAGTATGGGATAACTGCGCATCAT
CGCAAATCATTCGAGCCGATTAAATCAATGATAAAAACAGAAGAAAACGCAAAGACAATTACGAAACCGTCGTAA

Upstream 100 bases:

>100_bases
ATAGATTATGAATCGGTTGTAGAATTGATTATAAGAGATATACGTAACGAAAAAATTGGAAAATATACATTCGATCATAT
TTCAATGTTAGAGGTTGATG

Downstream 100 bases:

>100_bases
TTGTCTGTTTTTTAAGCGTTTGCGGTTTACAATAGCGCTTTCATTTTTTATAATTGGAACGTAAGCTAAATTAATGCGCA
CTATAGGAGGATGGACAATG

Product: ribonuclease HII

Products: NA

Alternate protein names: RNase HII

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MKSNDYTIASLKEKVREMNQAELIDFFEEESRSGALKVKQARVKQIAQETQAIHEYEQMLEYERRYNGKVVCGIDEVGRG
PLAGPVIACAVILNDGHHYIGLNDSKQLSKHKRASLYDALTQSVTYAIGAASVEEIDKFNIYEATKLAMHRAIDKLPVKP
DVLLIDAMNLNTGLIEESIIKGDAKSVSIAAASVIAKVYRDHLMEEIHEEFPYYDFNRNAGYGTKRHLDGLMQYGITAHH
RKSFEPIKSMIKTEENAKTITKPS

Sequences:

>Translated_264_residues
MKSNDYTIASLKEKVREMNQAELIDFFEEESRSGALKVKQARVKQIAQETQAIHEYEQMLEYERRYNGKVVCGIDEVGRG
PLAGPVIACAVILNDGHHYIGLNDSKQLSKHKRASLYDALTQSVTYAIGAASVEEIDKFNIYEATKLAMHRAIDKLPVKP
DVLLIDAMNLNTGLIEESIIKGDAKSVSIAAASVIAKVYRDHLMEEIHEEFPYYDFNRNAGYGTKRHLDGLMQYGITAHH
RKSFEPIKSMIKTEENAKTITKPS
>Mature_264_residues
MKSNDYTIASLKEKVREMNQAELIDFFEEESRSGALKVKQARVKQIAQETQAIHEYEQMLEYERRYNGKVVCGIDEVGRG
PLAGPVIACAVILNDGHHYIGLNDSKQLSKHKRASLYDALTQSVTYAIGAASVEEIDKFNIYEATKLAMHRAIDKLPVKP
DVLLIDAMNLNTGLIEESIIKGDAKSVSIAAASVIAKVYRDHLMEEIHEEFPYYDFNRNAGYGTKRHLDGLMQYGITAHH
RKSFEPIKSMIKTEENAKTITKPS

Specific function: Endonuclease that specifically degrades the RNA of RNA- DNA hybrids

COG id: COG0164

COG function: function code L; Ribonuclease HII

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase HII family

Homologues:

Organism=Escherichia coli, GI1786380, Length=192, Percent_Identity=41.6666666666667, Blast_Score=153, Evalue=1e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNH2_MACCJ (B9EBC6)

Other databases:

- EMBL:   AP009484
- RefSeq:   YP_002560233.1
- GeneID:   7389955
- GenomeReviews:   AP009484_GR
- KEGG:   mcl:MCCL_0830
- OMA:   RLGPTPI
- GO:   GO:0005737
- HAMAP:   MF_00052_B
- InterPro:   IPR022898
- InterPro:   IPR001352
- InterPro:   IPR012337
- PANTHER:   PTHR10954

Pfam domain/function: PF01351 RNase_HII; SSF53098 RNaseH_fold

EC number: =3.1.26.4

Molecular weight: Translated: 29719; Mature: 29719

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSNDYTIASLKEKVREMNQAELIDFFEEESRSGALKVKQARVKQIAQETQAIHEYEQML
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
EYERRYNGKVVCGIDEVGRGPLAGPVIACAVILNDGHHYIGLNDSKQLSKHKRASLYDAL
HHHHHCCCEEEECHHHHCCCCCCHHHHHHHHHEECCCEEECCCCHHHHHHHHHHHHHHHH
TQSVTYAIGAASVEEIDKFNIYEATKLAMHRAIDKLPVKPDVLLIDAMNLNTGLIEESII
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHH
KGDAKSVSIAAASVIAKVYRDHLMEEIHEEFPYYDFNRNAGYGTKRHLDGLMQYGITAHH
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCHHHH
RKSFEPIKSMIKTEENAKTITKPS
HCCHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MKSNDYTIASLKEKVREMNQAELIDFFEEESRSGALKVKQARVKQIAQETQAIHEYEQML
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
EYERRYNGKVVCGIDEVGRGPLAGPVIACAVILNDGHHYIGLNDSKQLSKHKRASLYDAL
HHHHHCCCEEEECHHHHCCCCCCHHHHHHHHHEECCCEEECCCCHHHHHHHHHHHHHHHH
TQSVTYAIGAASVEEIDKFNIYEATKLAMHRAIDKLPVKPDVLLIDAMNLNTGLIEESII
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHH
KGDAKSVSIAAASVIAKVYRDHLMEEIHEEFPYYDFNRNAGYGTKRHLDGLMQYGITAHH
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCHHHH
RKSFEPIKSMIKTEENAKTITKPS
HCCHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA