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The map label for this gene is sucC

Identifier: 222151080

GI number: 222151080

Start: 906267

End: 907436

Strand: Direct

Name: sucC

Synonym: MCCL_0831

Alternate gene names: 222151080

Gene position: 906267-907436 (Clockwise)

Preceding gene: 222151079

Following gene: 222151081

Centisome position: 43.11

GC content: 38.55

Gene sequence:

>1170_bases
ATGAATATCCATGAGTATCAAGGGAAAGAAATTTTTCGCTCTATGGGTGTAGCAGTTCCGAACGGTTCTGTTGCTTATAC
ACCTGAAGAAGCAGTTGAAGTAGCTAAAGGTCTGAAAGAAGGGGTTTACGTCGTTAAAGCTCAAATTCACGCTGGTGGCC
GTGGTAAAGCTGGTGGTGTTAAGATTGCAAAATCTTTAGACGAAGTTGAAAGCTACGCGAAAGAATTACTTGGAAAAGTA
TTAGTTACGCATCAAACTGGTCCTGAAGGTAAGGAAGTTAAACGTCTTCTAGTTGAAGAAGGATGCGATATTAAAAAAGA
ATATTATTTAGGGTTCGTACTAGACCGTGCTACAGATAGCGTAGTATTAATGGGGTCTGAAGAAGGTGGAACTGAAATTG
AAGAGGTTGCTGAAGCAACGCCTGAAAAAATCTTCAAAGAAGTGATCGATCCAGTTGTTGGATTAATGCCTTATCAGGCA
CGTCGTTTAGCATTTAACATTAACATTCCGAAAGAATCTGTAAATAAAGCAGTAAAAATTATGTTAGGTTTATATGATGT
ATTCATGAAGAAAGATGCATCTATTATTGAAATTAACCCGCTTGTAACGACAGGCGACGGTGAAGTGTTAGCGCTTGATG
CTAAAATCAACTTTGATGCAAATGCATTATTCCGTCAAAAAGACGTGATGGAATTACGCGATTTAGATGAAGAGGATCCA
AAGGAAATTGAAGCATCTAAATATGATTTATCATATATCGCTTTAGATGGAAATATCGGTTGTATGGTTAACGGTGCCGG
TCTTGCAATGGCGACGATGGATACAATTAATCATTTCGGCGGAAATCCGGCGAATTTCCTTGATGTAGGGGGCGGCGCAA
CGAAAGAGAAAGTTACTGAAGCATTCAAGATCATTTTAGGTGATGAGAAGGTTGAAGGTATTTTCGTTAATATCTTCGGT
GGCATCATGAAGTGTGATGTTATCGCTGAAGGTGTTGTTGCAGCAGCGAAAGAATTAGAATTAACAATTCCATTAGTAGT
ACGTTTAGAAGGTACAAACGTGGATCAAGGTAAAGAAATTCTAGGTAATTCAGGATTAGCAATTACACCTGCAAGCACAA
TGGCTGAAGGTGCACAAAAAATCGTTGAATTAGTAAAAGAAGCTAAATAG

Upstream 100 bases:

>100_bases
TAATTGTCTGTTTTTTAAGCGTTTGCGGTTTACAATAGCGCTTTCATTTTTTATAATTGGAACGTAAGCTAAATTAATGC
GCACTATAGGAGGATGGACA

Downstream 100 bases:

>100_bases
GAAGCGGGGATAATCGTGGGAGTATTTATTGATAAAGATACGAAAGTAATCGTACAAGGTATTACAGGATCAACAGCATT
ATTTCATACGAAACAAATGA

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MNIHEYQGKEIFRSMGVAVPNGSVAYTPEEAVEVAKGLKEGVYVVKAQIHAGGRGKAGGVKIAKSLDEVESYAKELLGKV
LVTHQTGPEGKEVKRLLVEEGCDIKKEYYLGFVLDRATDSVVLMGSEEGGTEIEEVAEATPEKIFKEVIDPVVGLMPYQA
RRLAFNINIPKESVNKAVKIMLGLYDVFMKKDASIIEINPLVTTGDGEVLALDAKINFDANALFRQKDVMELRDLDEEDP
KEIEASKYDLSYIALDGNIGCMVNGAGLAMATMDTINHFGGNPANFLDVGGGATKEKVTEAFKIILGDEKVEGIFVNIFG
GIMKCDVIAEGVVAAAKELELTIPLVVRLEGTNVDQGKEILGNSGLAITPASTMAEGAQKIVELVKEAK

Sequences:

>Translated_389_residues
MNIHEYQGKEIFRSMGVAVPNGSVAYTPEEAVEVAKGLKEGVYVVKAQIHAGGRGKAGGVKIAKSLDEVESYAKELLGKV
LVTHQTGPEGKEVKRLLVEEGCDIKKEYYLGFVLDRATDSVVLMGSEEGGTEIEEVAEATPEKIFKEVIDPVVGLMPYQA
RRLAFNINIPKESVNKAVKIMLGLYDVFMKKDASIIEINPLVTTGDGEVLALDAKINFDANALFRQKDVMELRDLDEEDP
KEIEASKYDLSYIALDGNIGCMVNGAGLAMATMDTINHFGGNPANFLDVGGGATKEKVTEAFKIILGDEKVEGIFVNIFG
GIMKCDVIAEGVVAAAKELELTIPLVVRLEGTNVDQGKEILGNSGLAITPASTMAEGAQKIVELVKEAK
>Mature_389_residues
MNIHEYQGKEIFRSMGVAVPNGSVAYTPEEAVEVAKGLKEGVYVVKAQIHAGGRGKAGGVKIAKSLDEVESYAKELLGKV
LVTHQTGPEGKEVKRLLVEEGCDIKKEYYLGFVLDRATDSVVLMGSEEGGTEIEEVAEATPEKIFKEVIDPVVGLMPYQA
RRLAFNINIPKESVNKAVKIMLGLYDVFMKKDASIIEINPLVTTGDGEVLALDAKINFDANALFRQKDVMELRDLDEEDP
KEIEASKYDLSYIALDGNIGCMVNGAGLAMATMDTINHFGGNPANFLDVGGGATKEKVTEAFKIILGDEKVEGIFVNIFG
GIMKCDVIAEGVVAAAKELELTIPLVVRLEGTNVDQGKEILGNSGLAITPASTMAEGAQKIVELVKEAK

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain

Homologues:

Organism=Homo sapiens, GI11321583, Length=391, Percent_Identity=49.616368286445, Blast_Score=377, Evalue=1e-104,
Organism=Homo sapiens, GI157779135, Length=378, Percent_Identity=50.2645502645503, Blast_Score=354, Evalue=8e-98,
Organism=Homo sapiens, GI294862256, Length=382, Percent_Identity=48.4293193717278, Blast_Score=334, Evalue=7e-92,
Organism=Escherichia coli, GI1786948, Length=386, Percent_Identity=53.1088082901554, Blast_Score=419, Evalue=1e-118,
Organism=Caenorhabditis elegans, GI17539378, Length=391, Percent_Identity=46.2915601023018, Blast_Score=344, Evalue=4e-95,
Organism=Caenorhabditis elegans, GI17567829, Length=390, Percent_Identity=46.1538461538462, Blast_Score=333, Evalue=1e-91,
Organism=Saccharomyces cerevisiae, GI6321683, Length=396, Percent_Identity=44.9494949494949, Blast_Score=350, Evalue=2e-97,
Organism=Drosophila melanogaster, GI161078106, Length=402, Percent_Identity=46.0199004975124, Blast_Score=347, Evalue=6e-96,
Organism=Drosophila melanogaster, GI24645208, Length=402, Percent_Identity=46.0199004975124, Blast_Score=347, Evalue=6e-96,
Organism=Drosophila melanogaster, GI281361397, Length=403, Percent_Identity=46.1538461538462, Blast_Score=346, Evalue=1e-95,
Organism=Drosophila melanogaster, GI281361395, Length=403, Percent_Identity=46.1538461538462, Blast_Score=346, Evalue=1e-95,
Organism=Drosophila melanogaster, GI21356231, Length=390, Percent_Identity=47.6923076923077, Blast_Score=338, Evalue=5e-93,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SUCC_MACCJ (B9EBC7)

Other databases:

- EMBL:   AP009484
- RefSeq:   YP_002560234.1
- ProteinModelPortal:   B9EBC7
- GeneID:   7389513
- GenomeReviews:   AP009484_GR
- KEGG:   mcl:MCCL_0831
- OMA:   KKELYVS
- ProtClustDB:   PRK00696
- HAMAP:   MF_00558
- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102
- Gene3D:   G3DSA:3.30.1490.20
- Gene3D:   G3DSA:3.30.470.20
- Gene3D:   G3DSA:3.40.50.261
- PANTHER:   PTHR11815
- TIGRFAMs:   TIGR01016

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA; SSF52210 CoA_ligase

EC number: =6.2.1.5

Molecular weight: Translated: 41840; Mature: 41840

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: PS50975 ATP_GRASP; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIHEYQGKEIFRSMGVAVPNGSVAYTPEEAVEVAKGLKEGVYVVKAQIHAGGRGKAGGV
CCCCHHCHHHHHHHCCCCCCCCCEEECHHHHHHHHHHHHCCEEEEEEEEECCCCCCCCCH
KIAKSLDEVESYAKELLGKVLVTHQTGPEGKEVKRLLVEEGCDIKKEYYLGFVLDRATDS
HHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHCCCCCCHHHEEEEEEECCCCC
VVLMGSEEGGTEIEEVAEATPEKIFKEVIDPVVGLMPYQARRLAFNINIPKESVNKAVKI
EEEEECCCCCCHHHHHHHCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHH
MLGLYDVFMKKDASIIEINPLVTTGDGEVLALDAKINFDANALFRQKDVMELRDLDEEDP
HHHHHHHHHHCCCCEEEECCEEECCCCCEEEEEEEECCCCHHHHHHHHHHHHHCCCCCCC
KEIEASKYDLSYIALDGNIGCMVNGAGLAMATMDTINHFGGNPANFLDVGGGATKEKVTE
HHHCCCCEEEEEEEEECCEEEEEECCCEEHHHHHHHHHCCCCCCCEEECCCCCCHHHHHH
AFKIILGDEKVEGIFVNIFGGIMKCDVIAEGVVAAAKELELTIPLVVRLEGTNVDQGKEI
HHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCEEEEEEEEEEECCCCCCCHHH
LGNSGLAITPASTMAEGAQKIVELVKEAK
HCCCCEEECCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNIHEYQGKEIFRSMGVAVPNGSVAYTPEEAVEVAKGLKEGVYVVKAQIHAGGRGKAGGV
CCCCHHCHHHHHHHCCCCCCCCCEEECHHHHHHHHHHHHCCEEEEEEEEECCCCCCCCCH
KIAKSLDEVESYAKELLGKVLVTHQTGPEGKEVKRLLVEEGCDIKKEYYLGFVLDRATDS
HHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHCCCCCCHHHEEEEEEECCCCC
VVLMGSEEGGTEIEEVAEATPEKIFKEVIDPVVGLMPYQARRLAFNINIPKESVNKAVKI
EEEEECCCCCCHHHHHHHCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHH
MLGLYDVFMKKDASIIEINPLVTTGDGEVLALDAKINFDANALFRQKDVMELRDLDEEDP
HHHHHHHHHHCCCCEEEECCEEECCCCCEEEEEEEECCCCHHHHHHHHHHHHHCCCCCCC
KEIEASKYDLSYIALDGNIGCMVNGAGLAMATMDTINHFGGNPANFLDVGGGATKEKVTE
HHHCCCCEEEEEEEEECCEEEEEECCCEEHHHHHHHHHCCCCCCCEEECCCCCCHHHHHH
AFKIILGDEKVEGIFVNIFGGIMKCDVIAEGVVAAAKELELTIPLVVRLEGTNVDQGKEI
HHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCEEEEEEEEEEECCCCCCCHHH
LGNSGLAITPASTMAEGAQKIVELVKEAK
HCCCCEEECCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA