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The map label for this gene is purE [H]

Identifier: 222150937

GI number: 222150937

Start: 739985

End: 740422

Strand: Direct

Name: purE [H]

Synonym: MCCL_0687

Alternate gene names: 222150937

Gene position: 739985-740422 (Clockwise)

Preceding gene: 222150935

Following gene: 222150938

Centisome position: 35.2

GC content: 47.72

Gene sequence:

>438_bases
ATGAAAGAATCGGTTACAATACTTGAAGCTTTCGGCATCGACTATGAGACGAGTGTTGTATCTGCGCATCGTACGCCACT
TACGATGGTTGATTTTGCGAAGTCTGCTCGTAAGAAAGGCATCGAGATCATTATCGCGGGTGCTGGTGGTGCGGCGCACT
TGCCGGGAATGGTCGCTTCGATGACGACGCTTCCAGTGATCGGTGTACCGATTGAATCGAAAGCTTTGAAGGGAATGGAT
TCCTTATTATCAATCGTACAGATGCCTGGTGGAATTCCGGTAGCCACGACTGCAATCGGTAAAGCTGGTGCTAAGAATGC
AGGGATTCTTGCCGCACGTATGCTCAGTCTGAAGGATACCGCTTTAGTAGCTCAGCTGGATGATTATGAAGCATCTTTAG
TAAAGAAAGTGGAGGCGATGCAGCATGACCTTAAATAA

Upstream 100 bases:

>100_bases
AGTAATATACACATAAATGAAGGCGCTTTTCAAATAATTATAAAGGGTGATAGTTGTGACAGTAGCAGTAATAATGGGGT
CTTCTTCTGACTGGGAGACG

Downstream 100 bases:

>100_bases
TTTCGCGCTCGGTGACACGATTGGTATCATCGGCGGGGGTCAGCTGGGTAAGATGATGGCACAGTCTGCACAGCGCATGG
GATTTAAAGTTGCTGTGCTT

Product: hypothetical protein

Products: NA

Alternate protein names: N5-CAIR mutase; 5-(carboxyamino)imidazole ribonucleotide mutase [H]

Number of amino acids: Translated: 145; Mature: 145

Protein sequence:

>145_residues
MKESVTILEAFGIDYETSVVSAHRTPLTMVDFAKSARKKGIEIIIAGAGGAAHLPGMVASMTTLPVIGVPIESKALKGMD
SLLSIVQMPGGIPVATTAIGKAGAKNAGILAARMLSLKDTALVAQLDDYEASLVKKVEAMQHDLK

Sequences:

>Translated_145_residues
MKESVTILEAFGIDYETSVVSAHRTPLTMVDFAKSARKKGIEIIIAGAGGAAHLPGMVASMTTLPVIGVPIESKALKGMD
SLLSIVQMPGGIPVATTAIGKAGAKNAGILAARMLSLKDTALVAQLDDYEASLVKKVEAMQHDLK
>Mature_145_residues
MKESVTILEAFGIDYETSVVSAHRTPLTMVDFAKSARKKGIEIIIAGAGGAAHLPGMVASMTTLPVIGVPIESKALKGMD
SLLSIVQMPGGIPVATTAIGKAGAKNAGILAARMLSLKDTALVAQLDDYEASLVKKVEAMQHDLK

Specific function: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) [H]

COG id: COG0041

COG function: function code F; Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AIR carboxylase family [H]

Homologues:

Organism=Escherichia coli, GI1786734, Length=137, Percent_Identity=53.2846715328467, Blast_Score=119, Evalue=7e-29,
Organism=Saccharomyces cerevisiae, GI6324702, Length=129, Percent_Identity=53.4883720930233, Blast_Score=141, Evalue=5e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000031 [H]

Pfam domain/function: PF00731 AIRC [H]

EC number: =5.4.99.18 [H]

Molecular weight: Translated: 15044; Mature: 15044

Theoretical pI: Translated: 8.96; Mature: 8.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKESVTILEAFGIDYETSVVSAHRTPLTMVDFAKSARKKGIEIIIAGAGGAAHLPGMVAS
CCCCCEEHHHHCCCCCHHHHHCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHH
MTTLPVIGVPIESKALKGMDSLLSIVQMPGGIPVATTAIGKAGAKNAGILAARMLSLKDT
HHHCCEECCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHH
ALVAQLDDYEASLVKKVEAMQHDLK
HHEEHHCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKESVTILEAFGIDYETSVVSAHRTPLTMVDFAKSARKKGIEIIIAGAGGAAHLPGMVAS
CCCCCEEHHHHCCCCCHHHHHCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHH
MTTLPVIGVPIESKALKGMDSLLSIVQMPGGIPVATTAIGKAGAKNAGILAARMLSLKDT
HHHCCEECCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHH
ALVAQLDDYEASLVKKVEAMQHDLK
HHEEHHCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]