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The map label for this gene is setC [H]

Identifier: 222150679

GI number: 222150679

Start: 454307

End: 455506

Strand: Direct

Name: setC [H]

Synonym: MCCL_0429

Alternate gene names: 222150679

Gene position: 454307-455506 (Clockwise)

Preceding gene: 222150678

Following gene: 222150680

Centisome position: 21.61

GC content: 38.25

Gene sequence:

>1200_bases
ATGTTTCGAGATCTTCTCACAATTAAAAACTATAAATTATTTCTTATCAATATGATTCTGCTTATGGCTTTAGCAATTAC
AGTGCCGTTCTTTGTCCTGTATGCAACTCAGGAACTCGGAATGACACGAGGATTATACGGTGTTATGATGGCGTTGTTTG
CCTTGGCAGGATTTATGGTCAATACCATTGTTGCAAGGTTTTCTGATCGGGCGAACTTTAATCGTAAGTATATGATCATG
TTTTCAGTAATGATGGCGGCAATCGCATTCAGTACATATTTTTATATCAATAATCCTGTCGTTTTCATCATGATATACGT
ATTTTTTGGAGGTATGGGTGCGCCTGCTATGCCACAGCTTTATGCATCAGCGCGAGAAAGTATCAATGTGTCAGCCTCAA
GTAAAAATGCTGTCTTTGCGAATACGCTCCTTCGTTCTATGTTTAGCTTCGGCTTCTTGTTCGGACCGCTCGTTGGAACA
GTTTTGCTTAAGAAGTTTGGATTTGCTGGAATATTTGGCGGCACCATTCTGCTTTATATTATTGTATTATTGTCGTTTTT
ATTCTTTTATAAAGAGGTTAAAGTAGAGAAACCAGCACATACTAAAGGTCACATTGAGCCCGTTGCACCGAACCTTTTGA
AAGATACGTACTTGCTTATTCCATTCCTCGCTTTTGTATTCTTACATATTGGTCAATGGATGTATACGCTGAATATGCCT
TTATTCGTAACAGAATTCTTAAATGCAGATGAAGCGAATGTTGGTTATTTAGCAAGCTTATGTGCAGGACTTGAAGTTCC
ATTTATGATTATTCTAGGGATATTAGCGAGCAGATTTCAAACGCGTACATTATTAATGATCGGTGCTATATTTGGTGGAG
GCTATTATCTTTCAATCGGGCTATTTGACAGTGTGACAGCGATGCTTATCGGTCAAATTGGGTTAGCGTTCTTCTTAGCG
ATACTGCTAGGTTTAGGAATCAGTTACTTTCAGGATACATTGCCAGACTTTCCGGGATATGCATCGACATTATTTTCTAA
TGCGATGATTGCAGGACAACTACTCGGTAACCTGCTTGGTGGAGTTATGAGTGACATTGTAGGACTAGGAAATGTATTTT
ATGTATCTTCGTCGTTCGTATTGATTGCATTTATCTTATTAATATTTACGAAACCCGTTAAGATGGAGGATTTAGCATGA

Upstream 100 bases:

>100_bases
TTTAGGTTGATCGGCTACATCATTAAGTCGCAGTTCTCACATAAAAATGTAATTTCATATATAATAAAACAAAATGAATC
TAATGAAAAGAGTGTGTTCA

Downstream 100 bases:

>100_bases
TGGTATTATTATGGACGTTTGTCATTATTAGTTTTATCGCAGCATTTGTTGGGCTGGTCGTACCAATGTTGCCAGGTGTG
CTGTTGATGTGGGTAGGTTT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MFRDLLTIKNYKLFLINMILLMALAITVPFFVLYATQELGMTRGLYGVMMALFALAGFMVNTIVARFSDRANFNRKYMIM
FSVMMAAIAFSTYFYINNPVVFIMIYVFFGGMGAPAMPQLYASARESINVSASSKNAVFANTLLRSMFSFGFLFGPLVGT
VLLKKFGFAGIFGGTILLYIIVLLSFLFFYKEVKVEKPAHTKGHIEPVAPNLLKDTYLLIPFLAFVFLHIGQWMYTLNMP
LFVTEFLNADEANVGYLASLCAGLEVPFMIILGILASRFQTRTLLMIGAIFGGGYYLSIGLFDSVTAMLIGQIGLAFFLA
ILLGLGISYFQDTLPDFPGYASTLFSNAMIAGQLLGNLLGGVMSDIVGLGNVFYVSSSFVLIAFILLIFTKPVKMEDLA

Sequences:

>Translated_399_residues
MFRDLLTIKNYKLFLINMILLMALAITVPFFVLYATQELGMTRGLYGVMMALFALAGFMVNTIVARFSDRANFNRKYMIM
FSVMMAAIAFSTYFYINNPVVFIMIYVFFGGMGAPAMPQLYASARESINVSASSKNAVFANTLLRSMFSFGFLFGPLVGT
VLLKKFGFAGIFGGTILLYIIVLLSFLFFYKEVKVEKPAHTKGHIEPVAPNLLKDTYLLIPFLAFVFLHIGQWMYTLNMP
LFVTEFLNADEANVGYLASLCAGLEVPFMIILGILASRFQTRTLLMIGAIFGGGYYLSIGLFDSVTAMLIGQIGLAFFLA
ILLGLGISYFQDTLPDFPGYASTLFSNAMIAGQLLGNLLGGVMSDIVGLGNVFYVSSSFVLIAFILLIFTKPVKMEDLA
>Mature_399_residues
MFRDLLTIKNYKLFLINMILLMALAITVPFFVLYATQELGMTRGLYGVMMALFALAGFMVNTIVARFSDRANFNRKYMIM
FSVMMAAIAFSTYFYINNPVVFIMIYVFFGGMGAPAMPQLYASARESINVSASSKNAVFANTLLRSMFSFGFLFGPLVGT
VLLKKFGFAGIFGGTILLYIIVLLSFLFFYKEVKVEKPAHTKGHIEPVAPNLLKDTYLLIPFLAFVFLHIGQWMYTLNMP
LFVTEFLNADEANVGYLASLCAGLEVPFMIILGILASRFQTRTLLMIGAIFGGGYYLSIGLFDSVTAMLIGQIGLAFFLA
ILLGLGISYFQDTLPDFPGYASTLFSNAMIAGQLLGNLLGGVMSDIVGLGNVFYVSSSFVLIAFILLIFTKPVKMEDLA

Specific function: Involved in the efflux of sugars. The physiological role may be the detoxification of non-metabolizable sugar analogs [H]

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Set transporter family [H]

Homologues:

Organism=Escherichia coli, GI1790091, Length=370, Percent_Identity=27.027027027027, Blast_Score=137, Evalue=8e-34,
Organism=Escherichia coli, GI48994875, Length=372, Percent_Identity=27.6881720430108, Blast_Score=132, Evalue=5e-32,
Organism=Escherichia coli, GI1788495, Length=372, Percent_Identity=27.9569892473118, Blast_Score=125, Evalue=5e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR004750 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 44048; Mature: 44048

Theoretical pI: Translated: 9.21; Mature: 9.21

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
5.8 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
5.8 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFRDLLTIKNYKLFLINMILLMALAITVPFFVLYATQELGMTRGLYGVMMALFALAGFMV
CCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
NTIVARFSDRANFNRKYMIMFSVMMAAIAFSTYFYINNPVVFIMIYVFFGGMGAPAMPQL
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHH
YASARESINVSASSKNAVFANTLLRSMFSFGFLFGPLVGTVLLKKFGFAGIFGGTILLYI
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
IVLLSFLFFYKEVKVEKPAHTKGHIEPVAPNLLKDTYLLIPFLAFVFLHIGQWMYTLNMP
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
LFVTEFLNADEANVGYLASLCAGLEVPFMIILGILASRFQTRTLLMIGAIFGGGYYLSIG
HHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEH
LFDSVTAMLIGQIGLAFFLAILLGLGISYFQDTLPDFPGYASTLFSNAMIAGQLLGNLLG
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
GVMSDIVGLGNVFYVSSSFVLIAFILLIFTKPVKMEDLA
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MFRDLLTIKNYKLFLINMILLMALAITVPFFVLYATQELGMTRGLYGVMMALFALAGFMV
CCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
NTIVARFSDRANFNRKYMIMFSVMMAAIAFSTYFYINNPVVFIMIYVFFGGMGAPAMPQL
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHH
YASARESINVSASSKNAVFANTLLRSMFSFGFLFGPLVGTVLLKKFGFAGIFGGTILLYI
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
IVLLSFLFFYKEVKVEKPAHTKGHIEPVAPNLLKDTYLLIPFLAFVFLHIGQWMYTLNMP
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
LFVTEFLNADEANVGYLASLCAGLEVPFMIILGILASRFQTRTLLMIGAIFGGGYYLSIG
HHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEH
LFDSVTAMLIGQIGLAFFLAILLGLGISYFQDTLPDFPGYASTLFSNAMIAGQLLGNLLG
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
GVMSDIVGLGNVFYVSSSFVLIAFILLIFTKPVKMEDLA
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7686882; 9278503; 10209755; 10438463 [H]