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The map label for this gene is pdxH [H]

Identifier: 222111074

GI number: 222111074

Start: 2001735

End: 2002388

Strand: Direct

Name: pdxH [H]

Synonym: Dtpsy_1881

Alternate gene names: 222111074

Gene position: 2001735-2002388 (Clockwise)

Preceding gene: 222111073

Following gene: 222111076

Centisome position: 52.72

GC content: 68.96

Gene sequence:

>654_bases
ATGAGCCACAGCCCTCTTTCCTCCTCCATCGCCGACCTGCGCAAGAGCTACGAGCGCGCCGAGCTCAGCGAGGACGCCTC
CCACGCCGATCCCTTGCTGCAGTTCGACCAATGGCTGCGCGAAGCCATCGCTGCCCAGGTGCCCGAGCCCAACGCCATGA
CCGTGGCCACCGTGGGCAGCGACCTGCGTCCCAGCACCCGCGTGGTGCTCATCAAGGGGTATGACGCGCAGGGCATCGTC
TGGTACACCAACTACGACAGCCGCAAGGGCCGCCAGCTGGCCGGCAACCCCTATGCCGCGCTGCAATTCCACTGGGTGGA
GCTGGAGCGCGTGGTGCGCATCGAGGGCGTCGTGGAAAAGGTGAGCGACGAGGAAAGCGACACCTATTTCCACAGCCGCC
CGCTGGACTCGCGCATCGGCGCCTGGGCCAGCCCGCAAAGCCAGGTCATCGCCAGCCGCGGCGTGCTGGTGGCCAACGCC
GCCAAGTATGGCGCGCAGTTCCTGCTCAAGCCGCCCCGCCCGCCGCACTGGGGGGGCTTTCGCCTGCGGCCGGATCAGTG
GGAGTTCTGGCAGGGCCGCAAGAGCCGCCTGCACGACCGGTTGCGCTACCGCCTGGAGGACGGCACGTGGGAGCGCGAGC
GGCTGGCGCCGTAA

Upstream 100 bases:

>100_bases
TCACCCAACCTACCGGCAACGCGGGCGCGCGCCTGGCGTGCGCGGTGATCGCCGGTCGCTGATCGTGCAGGGCTGGGCGC
CCTGCGGGCACAATCCCCGC

Downstream 100 bases:

>100_bases
GCGCCCGGAAGACGCCCTGCTCCACGCGCGTCTTCAACGCATGTTCAATGCATGAAGAACTGCGCCAACACCAGCACCAC
CGGCAGCGTGATCAGCGCCA

Product: pyridoxamine 5'-phosphate oxidase

Products: NA

Alternate protein names: PNP/PMP oxidase; PNPOx; Pyridoxal 5'-phosphate synthase [H]

Number of amino acids: Translated: 217; Mature: 216

Protein sequence:

>217_residues
MSHSPLSSSIADLRKSYERAELSEDASHADPLLQFDQWLREAIAAQVPEPNAMTVATVGSDLRPSTRVVLIKGYDAQGIV
WYTNYDSRKGRQLAGNPYAALQFHWVELERVVRIEGVVEKVSDEESDTYFHSRPLDSRIGAWASPQSQVIASRGVLVANA
AKYGAQFLLKPPRPPHWGGFRLRPDQWEFWQGRKSRLHDRLRYRLEDGTWERERLAP

Sequences:

>Translated_217_residues
MSHSPLSSSIADLRKSYERAELSEDASHADPLLQFDQWLREAIAAQVPEPNAMTVATVGSDLRPSTRVVLIKGYDAQGIV
WYTNYDSRKGRQLAGNPYAALQFHWVELERVVRIEGVVEKVSDEESDTYFHSRPLDSRIGAWASPQSQVIASRGVLVANA
AKYGAQFLLKPPRPPHWGGFRLRPDQWEFWQGRKSRLHDRLRYRLEDGTWERERLAP
>Mature_216_residues
SHSPLSSSIADLRKSYERAELSEDASHADPLLQFDQWLREAIAAQVPEPNAMTVATVGSDLRPSTRVVLIKGYDAQGIVW
YTNYDSRKGRQLAGNPYAALQFHWVELERVVRIEGVVEKVSDEESDTYFHSRPLDSRIGAWASPQSQVIASRGVLVANAA
KYGAQFLLKPPRPPHWGGFRLRPDQWEFWQGRKSRLHDRLRYRLEDGTWERERLAP

Specific function: Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) [H]

COG id: COG0259

COG function: function code H; Pyridoxamine-phosphate oxidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pyridoxamine 5'-phosphate oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922498, Length=206, Percent_Identity=41.2621359223301, Blast_Score=162, Evalue=2e-40,
Organism=Escherichia coli, GI1787926, Length=218, Percent_Identity=44.954128440367, Blast_Score=184, Evalue=4e-48,
Organism=Caenorhabditis elegans, GI17553712, Length=226, Percent_Identity=41.1504424778761, Blast_Score=164, Evalue=5e-41,
Organism=Saccharomyces cerevisiae, GI6319509, Length=209, Percent_Identity=42.1052631578947, Blast_Score=143, Evalue=2e-35,
Organism=Drosophila melanogaster, GI45551845, Length=238, Percent_Identity=42.8571428571429, Blast_Score=168, Evalue=3e-42,
Organism=Drosophila melanogaster, GI24644901, Length=238, Percent_Identity=42.8571428571429, Blast_Score=168, Evalue=3e-42,
Organism=Drosophila melanogaster, GI24644903, Length=194, Percent_Identity=29.8969072164948, Blast_Score=74, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000659
- InterPro:   IPR019740
- InterPro:   IPR019576
- InterPro:   IPR011576
- InterPro:   IPR012349
- InterPro:   IPR009002 [H]

Pfam domain/function: PF10590 PNPOx_C; PF01243 Pyridox_oxidase [H]

EC number: =1.4.3.5 [H]

Molecular weight: Translated: 24811; Mature: 24680

Theoretical pI: Translated: 8.78; Mature: 8.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHSPLSSSIADLRKSYERAELSEDASHADPLLQFDQWLREAIAAQVPEPNAMTVATVGS
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCC
DLRPSTRVVLIKGYDAQGIVWYTNYDSRKGRQLAGNPYAALQFHWVELERVVRIEGVVEK
CCCCCCEEEEEECCCCCEEEEEECCCCCCCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHH
VSDEESDTYFHSRPLDSRIGAWASPQSQVIASRGVLVANAAKYGAQFLLKPPRPPHWGGF
HCCCCCCCEECCCCCHHHCCCCCCCHHHHHHHCCEEEECCHHHCCEEEECCCCCCCCCCE
RLRPDQWEFWQGRKSRLHDRLRYRLEDGTWERERLAP
EECCCCCHHHCCHHHHHHHHHHHHHCCCCCCHHCCCC
>Mature Secondary Structure 
SHSPLSSSIADLRKSYERAELSEDASHADPLLQFDQWLREAIAAQVPEPNAMTVATVGS
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCC
DLRPSTRVVLIKGYDAQGIVWYTNYDSRKGRQLAGNPYAALQFHWVELERVVRIEGVVEK
CCCCCCEEEEEECCCCCEEEEEECCCCCCCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHH
VSDEESDTYFHSRPLDSRIGAWASPQSQVIASRGVLVANAAKYGAQFLLKPPRPPHWGGF
HCCCCCCCEECCCCCHHHCCCCCCCHHHHHHHCCEEEECCHHHCCEEEECCCCCCCCCCE
RLRPDQWEFWQGRKSRLHDRLRYRLEDGTWERERLAP
EECCCCCHHHCCHHHHHHHHHHHHHCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA