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The map label for this gene is purL [H]

Identifier: 222110777

GI number: 222110777

Start: 1669812

End: 1673846

Strand: Direct

Name: purL [H]

Synonym: Dtpsy_1582

Alternate gene names: 222110777

Gene position: 1669812-1673846 (Clockwise)

Preceding gene: 222110774

Following gene: 222110779

Centisome position: 43.98

GC content: 68.35

Gene sequence:

>4035_bases
GTGACCTTGCACATCACCCCGCTGGAGGGCGGCAATGCCCTCAGCACCTTCCGCGCCCAGCAACTGCAACCCGCCCTGGC
GGCCATTCATCCCAAGATCGACGGCATTGCGGCGCGCTTCGTGCACCTGGTAGCTGGCGACGCCGCACCCGATGCCGCCG
CGCGCGAGCGCCTGGCCGCGCTGCTGACCTACGGCGACCCATACGCCGGCCCGCGGGACGGCATGGTGCTGTATGTCACT
CCGCGCCTGGGCACGGTGTCGCCCTGGGCGTCCAAGGCCACGGACATCGCCCACAACTGCGGCCTGGCGGTGCGCCGCAT
CGAGCGCATCACCGAATACCGCATCAGCCTCAAGGGCGGCCTGCTGGGTGGCAAGCCCGAGTTGAGCACCGAGCAGCTGC
AGCAGGTTGCGGCGCTCTTGCACGACCGCATGACGGAATCGGTGGTCACCACGCTGGACGAGGCACAGCGCCTGTTCACC
GAGCTGCAGGCCGAGCCCATGGCCTTCGTGGATGTGCTGCAGGGCGGGCGTGCGGCGCTGGAGGCTGCGAATAAGGCCTG
GGGCCTGGCCCTGGCCGACGACGAGATCGACTACCTGGTCAACGCCTTCACAGGCCTGGCGCGCAACCCCACCGACGTGG
AGTTGATGATGTTCGCCCAGGCCAACAGCGAGCACTGCCGCCACAAGATCTTCAACGCCCAGTTCACCATCGACGGCGTG
GCGCAGGACAAGAGCCTGTTCGGCATGATCCGCAACACCGAAGCCGTGTCGCCCCAGCATACCGTGGTGGCCTATGCCGA
CAACGCCTCCATCATGGAAGGCAGCGAGGTCGAGCAATTCATCGCCAAATTCGAGTCTTTCGCCCAACAGGTAAGCGCTC
CAAGCTATCAAAAGCGTAGTGCAACCCACCATGTACTGATGAAGGTGGAGACGCACAACCACCCCACGGCCATCTCGCCA
TTCCCCGGCGCTTCCACCGGCGCGGGCGGCGAGATCCGCGATGAGGGCGCTACCGGCCGCGGCTCCAAGCCCAAGGCGGG
TCTCACGGGCTTCACCGTGTCCAAGCTCTGGGGCAGCGAGGTGGGCAAGCCCGAGCACATCGCCAGCCCCCTGCAGATCA
TGACCGAGGGGCCGCTGGGCGGCGCCGCGTTCAACAACGAGTTCGGCCGGCCCAACCTGACGGGCTACTTCCGCGAATAC
GAGCAGGTGGTCGGAACGGGCGAGGGCGCCATCATCCGCGGCTACCACAAGCCCATCATGATCGCGGGCGGCCTGGGCAC
GATCGACGCGCGGCTCACCCAAAAAATCCTGTTCCCCGCCGGCACGCTGCTGATCCAGCTGGGCGGCCCCGGCATGCGCA
TCGGCATGGGCGGCGGCGCCGCCAGTTCCATGGCCACGGGCACCAACGCGGCGGAGCTGGACTTCGACTCCGTGCAGCGC
GGCAACCCCGAGATCGAGCGCCGCGCACAGGAGGTCATCAACCACTGCTGGGCGCAGGGTGACCAGAACCCGATCCTGGC
GATCCACGACGTGGGCGCGGGCGGCCTGTCGAACGCCTTCCCCGAGCTGACGAATGACGCGGGCCGCGGCGCGCGCTTCG
ACCTGCGCGCCGTGCCGCTGGAGGAGTCGGGCCTGGCGCCCAAGGAAATCTGGTCCAACGAGAGCCAGGAGCGCTATGTG
CTGGCCATCGCGCCCGAGTCGCTGGCGCAGTTCACGGCCTTCTGCGAGCGCGAGCGCTGCCCGTTTGCCGTGATCGGCAC
GGCCACCGAGGAGCGCCAACTGGTGCTGGAAGACACGGTCGTCGCATCCGGCGAGCAGAAGTACCCCGTGGACATGCCCA
TGGACGTGCTGCTGGGCAAGCCGCCCAAGATGCACCGCGATGTGACCAGCGTGCAGCGCAGCTTCGCGCCGCTGAACGTG
GACGGCCTGCCGCTGGAGAAGGCTGTGATCGAGGTGCTGGCCCACCCCACGGTGGCGTCCAAGCGCTTTCTCATCACCAT
CGGCGACCGCGCCGTGGGCGGCCTGACCCACCGCGACCAGATGGTGGGCCCCTGGCAGGTGCCCGTGGCCGACGCGGCCG
TGACGCTGGCCGACTTCCGTGGCTTTGCCGGCGAGGCCATGGCCATGGGCGAACGCACGCCGCTGGCGGCGCTCAATGCG
CCCGCGTCGGGCCGCATGGCGGTGGCGGAAAGCATCACCAACCTGTTGGCGGCACCCATCGAACTGCCGCGCGTAAAGCT
GTCGGCCAACTGGATGGCGGCCTGCGGCGAGCCCGGAGAAGACGCCGCGCTGTACGAGACCGTGAAGGCCGTGGGCATGG
AGCTGTGCCCGCAGCTGGGCATCTCCATCCCCGTGGGCAAGGACAGCCTGTCCATGCGCACCCAGTGGAGCGAGGACGGC
GAGACCAAGAAGGTCACCTCGCCCGTCAGCCTCATCATCACCGCGTTCGCCACGCTGGCCGACGTGCGCGGCACGCTCAC
GCCGCAGCTCGACGCCAAGGAAGAGGACACGACCCTCGTGCTGATCGACCTGGGCCGCGGCAAGATGCGCATGGGCGGCT
CCATCCTCGGGCAGGTGCTGAACCAGACCGGCGACGAGACGCCCGACCTGGACGACGCCAAGGATCTGATCGCCCTGGTG
GATGCCGTGAACGCGCTGCGCGCTAAAGGTGCGATCCTGGCCTACCACGACCGGGGCGACGGCGGCCTGCTGGCTACCGT
GGCCGAGATGGCCTTTGCCGGTCAGGTGGGCGTGGCGCTGAACGTGGACATGCTCATCACCGAGGGCGACGGCATCACCG
ACAGCCGCATGGACAGCGGCGAGGGCAAGAACTGGGGCGCCCAGATCAGCGGCCGGCGCGAGGAGCGCACGCTGCGCGCG
TTGTTCAACGAGGAACTGGGCGTGGTGCTGCAGGTGAGGACCAGCGAGCGCAACGAGGTCATGCAGACGCTGCGCGCGCA
CGGCCTGTCCACTTGCAGCCACTTCGTGGGCAAGACGCGCCCGCTGTCCTCGCCCATCGATGCAGGCAAGGGCGAGTTGC
AGGTGTGGCGCGATGCCAAGGCCGTGTTCAGCGCCAGCCTGCCGGACCTGCACCAGGTGTGGGACGCGGTGAGCTGGAAA
ATCTGCCAGCAGCGCGACAACCCCGCCTGCGCTGACAGCGAGCACGCCGCGGCCGGCGATCCCGCAGACCCCGGCATGCA
CGTGCAGCTCACGTTCGACCCATTGGACAACGTGGCCGCGCCGTACATCGCCACTGGCGCGCGCCCGCGTGTGGCGGTGC
TGCGCGAGCAGGGCGTGAACTCGCATGTGGAAATGGCCTACACCTTCACCGAGGCGGGCTTCGAGGCGTTCGACGTGCAC
ATGACCGACCTGCAGACCGGCCGTGCCGACCTTGCGCAGTTTGCTGGCGTGGTGGCCTGCGGCGGCTTCAGCTACGGCGA
CACGCTGGGCGCGGGCATCGGCTGGGCGCGCTCCATCACGTTCAACGAGCGCCTGTCGGCCCAGTTCCAGCAGTTCTTCG
CGCGTGGCGACACCTTTGCCCTGGGCGTGTGCAACGGCTGCCAGATGTTTGCCGAACTGGCCGACATCATCCCTGGCGCG
CAGGACTGGCCGCGCTTCACCACCAACCAGAGCCACCGCTTCGAGGCGCGCCTGTCGATGGTCGAAGTGCTGGAATCGCC
CAGCATCTTCCTTCAGGGCATGGCCGGCAGCCGCCTGCCGATCGCTGTGGCGCACGGCGAGGGCTATGCCAACTTCCAGT
ACCGTGGCAATGCCGACAAGGTGGTGCGTGCCATGCGCTTCGTGGACAACCATGGCCAGCCGACCGAGCGCTACCCGTTC
AACCCCAATGGCAGCGCCGGCGGGCTCACGGCCGTGACCACGGCGGATGGCCGCTTCACGGCCATGATGCCGCACCCCGA
GCGTGTGTTCCGCAACATCCAGATGAGCTGGACCGATCTGGCCGCCACGGGGGGCAAGGACGCGTTCAGCCCCTGGATGC
GCGTGTGGCGCAACGCACGCAAGTGGGTGGGGTGA

Upstream 100 bases:

>100_bases
GGCTCCCACCAACACGCGCTGCCGGCGCGGCGGCCCCATTCAGCGGCTGCCTCAACCAGCGGGCGAAACGCCTCTTTCTG
CCACCACACAGGCCGCTACC

Downstream 100 bases:

>100_bases
TCGGCGCCGCGGCGCGCGGCTAGCAGCCGCCGCGCACCTGGCACTCGGGCACGATGCGCCCGTGCGAGTCGCGCCACTGC
AGGGTCGGGCCGCCGGAAGA

Product: phosphoribosylformylglycinamidine synthase

Products: NA

Alternate protein names: FGAM synthase; FGAMS; Formylglycinamide ribotide amidotransferase; FGARAT; Formylglycinamide ribotide synthetase [H]

Number of amino acids: Translated: 1344; Mature: 1343

Protein sequence:

>1344_residues
MTLHITPLEGGNALSTFRAQQLQPALAAIHPKIDGIAARFVHLVAGDAAPDAAARERLAALLTYGDPYAGPRDGMVLYVT
PRLGTVSPWASKATDIAHNCGLAVRRIERITEYRISLKGGLLGGKPELSTEQLQQVAALLHDRMTESVVTTLDEAQRLFT
ELQAEPMAFVDVLQGGRAALEAANKAWGLALADDEIDYLVNAFTGLARNPTDVELMMFAQANSEHCRHKIFNAQFTIDGV
AQDKSLFGMIRNTEAVSPQHTVVAYADNASIMEGSEVEQFIAKFESFAQQVSAPSYQKRSATHHVLMKVETHNHPTAISP
FPGASTGAGGEIRDEGATGRGSKPKAGLTGFTVSKLWGSEVGKPEHIASPLQIMTEGPLGGAAFNNEFGRPNLTGYFREY
EQVVGTGEGAIIRGYHKPIMIAGGLGTIDARLTQKILFPAGTLLIQLGGPGMRIGMGGGAASSMATGTNAAELDFDSVQR
GNPEIERRAQEVINHCWAQGDQNPILAIHDVGAGGLSNAFPELTNDAGRGARFDLRAVPLEESGLAPKEIWSNESQERYV
LAIAPESLAQFTAFCERERCPFAVIGTATEERQLVLEDTVVASGEQKYPVDMPMDVLLGKPPKMHRDVTSVQRSFAPLNV
DGLPLEKAVIEVLAHPTVASKRFLITIGDRAVGGLTHRDQMVGPWQVPVADAAVTLADFRGFAGEAMAMGERTPLAALNA
PASGRMAVAESITNLLAAPIELPRVKLSANWMAACGEPGEDAALYETVKAVGMELCPQLGISIPVGKDSLSMRTQWSEDG
ETKKVTSPVSLIITAFATLADVRGTLTPQLDAKEEDTTLVLIDLGRGKMRMGGSILGQVLNQTGDETPDLDDAKDLIALV
DAVNALRAKGAILAYHDRGDGGLLATVAEMAFAGQVGVALNVDMLITEGDGITDSRMDSGEGKNWGAQISGRREERTLRA
LFNEELGVVLQVRTSERNEVMQTLRAHGLSTCSHFVGKTRPLSSPIDAGKGELQVWRDAKAVFSASLPDLHQVWDAVSWK
ICQQRDNPACADSEHAAAGDPADPGMHVQLTFDPLDNVAAPYIATGARPRVAVLREQGVNSHVEMAYTFTEAGFEAFDVH
MTDLQTGRADLAQFAGVVACGGFSYGDTLGAGIGWARSITFNERLSAQFQQFFARGDTFALGVCNGCQMFAELADIIPGA
QDWPRFTTNQSHRFEARLSMVEVLESPSIFLQGMAGSRLPIAVAHGEGYANFQYRGNADKVVRAMRFVDNHGQPTERYPF
NPNGSAGGLTAVTTADGRFTAMMPHPERVFRNIQMSWTDLAATGGKDAFSPWMRVWRNARKWVG

Sequences:

>Translated_1344_residues
MTLHITPLEGGNALSTFRAQQLQPALAAIHPKIDGIAARFVHLVAGDAAPDAAARERLAALLTYGDPYAGPRDGMVLYVT
PRLGTVSPWASKATDIAHNCGLAVRRIERITEYRISLKGGLLGGKPELSTEQLQQVAALLHDRMTESVVTTLDEAQRLFT
ELQAEPMAFVDVLQGGRAALEAANKAWGLALADDEIDYLVNAFTGLARNPTDVELMMFAQANSEHCRHKIFNAQFTIDGV
AQDKSLFGMIRNTEAVSPQHTVVAYADNASIMEGSEVEQFIAKFESFAQQVSAPSYQKRSATHHVLMKVETHNHPTAISP
FPGASTGAGGEIRDEGATGRGSKPKAGLTGFTVSKLWGSEVGKPEHIASPLQIMTEGPLGGAAFNNEFGRPNLTGYFREY
EQVVGTGEGAIIRGYHKPIMIAGGLGTIDARLTQKILFPAGTLLIQLGGPGMRIGMGGGAASSMATGTNAAELDFDSVQR
GNPEIERRAQEVINHCWAQGDQNPILAIHDVGAGGLSNAFPELTNDAGRGARFDLRAVPLEESGLAPKEIWSNESQERYV
LAIAPESLAQFTAFCERERCPFAVIGTATEERQLVLEDTVVASGEQKYPVDMPMDVLLGKPPKMHRDVTSVQRSFAPLNV
DGLPLEKAVIEVLAHPTVASKRFLITIGDRAVGGLTHRDQMVGPWQVPVADAAVTLADFRGFAGEAMAMGERTPLAALNA
PASGRMAVAESITNLLAAPIELPRVKLSANWMAACGEPGEDAALYETVKAVGMELCPQLGISIPVGKDSLSMRTQWSEDG
ETKKVTSPVSLIITAFATLADVRGTLTPQLDAKEEDTTLVLIDLGRGKMRMGGSILGQVLNQTGDETPDLDDAKDLIALV
DAVNALRAKGAILAYHDRGDGGLLATVAEMAFAGQVGVALNVDMLITEGDGITDSRMDSGEGKNWGAQISGRREERTLRA
LFNEELGVVLQVRTSERNEVMQTLRAHGLSTCSHFVGKTRPLSSPIDAGKGELQVWRDAKAVFSASLPDLHQVWDAVSWK
ICQQRDNPACADSEHAAAGDPADPGMHVQLTFDPLDNVAAPYIATGARPRVAVLREQGVNSHVEMAYTFTEAGFEAFDVH
MTDLQTGRADLAQFAGVVACGGFSYGDTLGAGIGWARSITFNERLSAQFQQFFARGDTFALGVCNGCQMFAELADIIPGA
QDWPRFTTNQSHRFEARLSMVEVLESPSIFLQGMAGSRLPIAVAHGEGYANFQYRGNADKVVRAMRFVDNHGQPTERYPF
NPNGSAGGLTAVTTADGRFTAMMPHPERVFRNIQMSWTDLAATGGKDAFSPWMRVWRNARKWVG
>Mature_1343_residues
TLHITPLEGGNALSTFRAQQLQPALAAIHPKIDGIAARFVHLVAGDAAPDAAARERLAALLTYGDPYAGPRDGMVLYVTP
RLGTVSPWASKATDIAHNCGLAVRRIERITEYRISLKGGLLGGKPELSTEQLQQVAALLHDRMTESVVTTLDEAQRLFTE
LQAEPMAFVDVLQGGRAALEAANKAWGLALADDEIDYLVNAFTGLARNPTDVELMMFAQANSEHCRHKIFNAQFTIDGVA
QDKSLFGMIRNTEAVSPQHTVVAYADNASIMEGSEVEQFIAKFESFAQQVSAPSYQKRSATHHVLMKVETHNHPTAISPF
PGASTGAGGEIRDEGATGRGSKPKAGLTGFTVSKLWGSEVGKPEHIASPLQIMTEGPLGGAAFNNEFGRPNLTGYFREYE
QVVGTGEGAIIRGYHKPIMIAGGLGTIDARLTQKILFPAGTLLIQLGGPGMRIGMGGGAASSMATGTNAAELDFDSVQRG
NPEIERRAQEVINHCWAQGDQNPILAIHDVGAGGLSNAFPELTNDAGRGARFDLRAVPLEESGLAPKEIWSNESQERYVL
AIAPESLAQFTAFCERERCPFAVIGTATEERQLVLEDTVVASGEQKYPVDMPMDVLLGKPPKMHRDVTSVQRSFAPLNVD
GLPLEKAVIEVLAHPTVASKRFLITIGDRAVGGLTHRDQMVGPWQVPVADAAVTLADFRGFAGEAMAMGERTPLAALNAP
ASGRMAVAESITNLLAAPIELPRVKLSANWMAACGEPGEDAALYETVKAVGMELCPQLGISIPVGKDSLSMRTQWSEDGE
TKKVTSPVSLIITAFATLADVRGTLTPQLDAKEEDTTLVLIDLGRGKMRMGGSILGQVLNQTGDETPDLDDAKDLIALVD
AVNALRAKGAILAYHDRGDGGLLATVAEMAFAGQVGVALNVDMLITEGDGITDSRMDSGEGKNWGAQISGRREERTLRAL
FNEELGVVLQVRTSERNEVMQTLRAHGLSTCSHFVGKTRPLSSPIDAGKGELQVWRDAKAVFSASLPDLHQVWDAVSWKI
CQQRDNPACADSEHAAAGDPADPGMHVQLTFDPLDNVAAPYIATGARPRVAVLREQGVNSHVEMAYTFTEAGFEAFDVHM
TDLQTGRADLAQFAGVVACGGFSYGDTLGAGIGWARSITFNERLSAQFQQFFARGDTFALGVCNGCQMFAELADIIPGAQ
DWPRFTTNQSHRFEARLSMVEVLESPSIFLQGMAGSRLPIAVAHGEGYANFQYRGNADKVVRAMRFVDNHGQPTERYPFN
PNGSAGGLTAVTTADGRFTAMMPHPERVFRNIQMSWTDLAATGGKDAFSPWMRVWRNARKWVG

Specific function: Unknown

COG id: COG0046

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI31657129, Length=1376, Percent_Identity=34.375, Blast_Score=680, Evalue=0.0,
Organism=Escherichia coli, GI48994899, Length=1353, Percent_Identity=54.5454545454545, Blast_Score=1405, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17553022, Length=1409, Percent_Identity=31.7955997161107, Blast_Score=598, Evalue=1e-171,
Organism=Saccharomyces cerevisiae, GI6321498, Length=1412, Percent_Identity=45.1133144475921, Blast_Score=1138, Evalue=0.0,
Organism=Drosophila melanogaster, GI24582111, Length=1323, Percent_Identity=35.6009070294785, Blast_Score=674, Evalue=0.0,
Organism=Drosophila melanogaster, GI24582109, Length=1323, Percent_Identity=35.6009070294785, Blast_Score=674, Evalue=0.0,
Organism=Drosophila melanogaster, GI17137292, Length=1323, Percent_Identity=35.6009070294785, Blast_Score=674, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR017926
- InterPro:   IPR010073
- InterPro:   IPR022940
- InterPro:   IPR016188 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: =6.3.5.3 [H]

Molecular weight: Translated: 144383; Mature: 144252

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLHITPLEGGNALSTFRAQQLQPALAAIHPKIDGIAARFVHLVAGDAAPDAAARERLAA
CEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHH
LLTYGDPYAGPRDGMVLYVTPRLGTVSPWASKATDIAHNCGLAVRRIERITEYRISLKGG
HHHCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHEEEECC
LLGGKPELSTEQLQQVAALLHDRMTESVVTTLDEAQRLFTELQAEPMAFVDVLQGGRAAL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHH
EAANKAWGLALADDEIDYLVNAFTGLARNPTDVELMMFAQANSEHCRHKIFNAQFTIDGV
HHCCHHCEEEECCCHHHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHCCCEEEECCC
AQDKSLFGMIRNTEAVSPQHTVVAYADNASIMEGSEVEQFIAKFESFAQQVSAPSYQKRS
CCCHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHC
ATHHVLMKVETHNHPTAISPFPGASTGAGGEIRDEGATGRGSKPKAGLTGFTVSKLWGSE
CCEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCC
VGKPEHIASPLQIMTEGPLGGAAFNNEFGRPNLTGYFREYEQVVGTGEGAIIRGYHKPIM
CCCCHHHCCCHHEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCEE
IAGGLGTIDARLTQKILFPAGTLLIQLGGPGMRIGMGGGAASSMATGTNAAELDFDSVQR
EECCCCCHHHHHHHHHHCCCCEEEEEECCCCEEEECCCCCCCHHCCCCCCCCCCHHHHHC
GNPEIERRAQEVINHCWAQGDQNPILAIHDVGAGGLSNAFPELTNDAGRGARFDLRAVPL
CCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCHHHCCCCCCCCEEEEEECCC
EESGLAPKEIWSNESQERYVLAIAPESLAQFTAFCERERCPFAVIGTATEERQLVLEDTV
CCCCCCHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEEHHH
VASGEQKYPVDMPMDVLLGKPPKMHRDVTSVQRSFAPLNVDGLPLEKAVIEVLAHPTVAS
EECCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCC
KRFLITIGDRAVGGLTHRDQMVGPWQVPVADAAVTLADFRGFAGEAMAMGERTPLAALNA
CEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHCCCCCCCEEECC
PASGRMAVAESITNLLAAPIELPRVKLSANWMAACGEPGEDAALYETVKAVGMELCPQLG
CCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCEECCCCCCCHHHHHHHHHHHHHHHHHCC
ISIPVGKDSLSMRTQWSEDGETKKVTSPVSLIITAFATLADVRGTLTPQLDAKEEDTTLV
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEE
LIDLGRGKMRMGGSILGQVLNQTGDETPDLDDAKDLIALVDAVNALRAKGAILAYHDRGD
EEECCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCC
GGLLATVAEMAFAGQVGVALNVDMLITEGDGITDSRMDSGEGKNWGAQISGRREERTLRA
CCHHHHHHHHHHCCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
LFNEELGVVLQVRTSERNEVMQTLRAHGLSTCSHFVGKTRPLSSPIDAGKGELQVWRDAK
HHCCCCCEEEEEECCCHHHHHHHHHHHCHHHHHHHHCCCCCCCCCCCCCCCCEEEHHHHH
AVFSASLPDLHQVWDAVSWKICQQRDNPACADSEHAAAGDPADPGMHVQLTFDPLDNVAA
HHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCC
PYIATGARPRVAVLREQGVNSHVEMAYTFTEAGFEAFDVHMTDLQTGRADLAQFAGVVAC
CCEECCCCCHHHHHHHCCCCCCEEEEEEEECCCCEEEEEEEHHCCCCHHHHHHHHHHHEE
GGFSYGDTLGAGIGWARSITFNERLSAQFQQFFARGDTFALGVCNGCQMFAELADIIPGA
CCCCCCCHHCCCCCCEEEEEHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHCCCC
QDWPRFTTNQSHRFEARLSMVEVLESPSIFLQGMAGSRLPIAVAHGEGYANFQYRGNADK
CCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCEEEEECCCCEEEEEEECCHHH
VVRAMRFVDNHGQPTERYPFNPNGSAGGLTAVTTADGRFTAMMPHPERVFRNIQMSWTDL
HHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECCCEEEEECCCHHHHHHHCCCCHHHH
AATGGKDAFSPWMRVWRNARKWVG
HCCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TLHITPLEGGNALSTFRAQQLQPALAAIHPKIDGIAARFVHLVAGDAAPDAAARERLAA
EEEEEECCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHH
LLTYGDPYAGPRDGMVLYVTPRLGTVSPWASKATDIAHNCGLAVRRIERITEYRISLKGG
HHHCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHEEEECC
LLGGKPELSTEQLQQVAALLHDRMTESVVTTLDEAQRLFTELQAEPMAFVDVLQGGRAAL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHH
EAANKAWGLALADDEIDYLVNAFTGLARNPTDVELMMFAQANSEHCRHKIFNAQFTIDGV
HHCCHHCEEEECCCHHHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHCCCEEEECCC
AQDKSLFGMIRNTEAVSPQHTVVAYADNASIMEGSEVEQFIAKFESFAQQVSAPSYQKRS
CCCHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHC
ATHHVLMKVETHNHPTAISPFPGASTGAGGEIRDEGATGRGSKPKAGLTGFTVSKLWGSE
CCEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCC
VGKPEHIASPLQIMTEGPLGGAAFNNEFGRPNLTGYFREYEQVVGTGEGAIIRGYHKPIM
CCCCHHHCCCHHEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCEE
IAGGLGTIDARLTQKILFPAGTLLIQLGGPGMRIGMGGGAASSMATGTNAAELDFDSVQR
EECCCCCHHHHHHHHHHCCCCEEEEEECCCCEEEECCCCCCCHHCCCCCCCCCCHHHHHC
GNPEIERRAQEVINHCWAQGDQNPILAIHDVGAGGLSNAFPELTNDAGRGARFDLRAVPL
CCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCHHHCCCCCCCCEEEEEECCC
EESGLAPKEIWSNESQERYVLAIAPESLAQFTAFCERERCPFAVIGTATEERQLVLEDTV
CCCCCCHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEEHHH
VASGEQKYPVDMPMDVLLGKPPKMHRDVTSVQRSFAPLNVDGLPLEKAVIEVLAHPTVAS
EECCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCC
KRFLITIGDRAVGGLTHRDQMVGPWQVPVADAAVTLADFRGFAGEAMAMGERTPLAALNA
CEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHCCCCCCCEEECC
PASGRMAVAESITNLLAAPIELPRVKLSANWMAACGEPGEDAALYETVKAVGMELCPQLG
CCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCEECCCCCCCHHHHHHHHHHHHHHHHHCC
ISIPVGKDSLSMRTQWSEDGETKKVTSPVSLIITAFATLADVRGTLTPQLDAKEEDTTLV
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEE
LIDLGRGKMRMGGSILGQVLNQTGDETPDLDDAKDLIALVDAVNALRAKGAILAYHDRGD
EEECCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCC
GGLLATVAEMAFAGQVGVALNVDMLITEGDGITDSRMDSGEGKNWGAQISGRREERTLRA
CCHHHHHHHHHHCCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
LFNEELGVVLQVRTSERNEVMQTLRAHGLSTCSHFVGKTRPLSSPIDAGKGELQVWRDAK
HHCCCCCEEEEEECCCHHHHHHHHHHHCHHHHHHHHCCCCCCCCCCCCCCCCEEEHHHHH
AVFSASLPDLHQVWDAVSWKICQQRDNPACADSEHAAAGDPADPGMHVQLTFDPLDNVAA
HHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCC
PYIATGARPRVAVLREQGVNSHVEMAYTFTEAGFEAFDVHMTDLQTGRADLAQFAGVVAC
CCEECCCCCHHHHHHHCCCCCCEEEEEEEECCCCEEEEEEEHHCCCCHHHHHHHHHHHEE
GGFSYGDTLGAGIGWARSITFNERLSAQFQQFFARGDTFALGVCNGCQMFAELADIIPGA
CCCCCCCHHCCCCCCEEEEEHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHCCCC
QDWPRFTTNQSHRFEARLSMVEVLESPSIFLQGMAGSRLPIAVAHGEGYANFQYRGNADK
CCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCEEEEECCCCEEEEEEECCHHH
VVRAMRFVDNHGQPTERYPFNPNGSAGGLTAVTTADGRFTAMMPHPERVFRNIQMSWTDL
HHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECCCEEEEECCCHHHHHHHCCCCHHHH
AATGGKDAFSPWMRVWRNARKWVG
HCCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]