Click here to switch to the map view.

The map label for this gene is hfq

Identifier: 222110308

GI number: 222110308

Start: 1143553

End: 1143804

Strand: Direct

Name: hfq

Synonym: Dtpsy_1095

Alternate gene names: 222110308

Gene position: 1143553-1143804 (Clockwise)

Preceding gene: 222110307

Following gene: 222110309

Centisome position: 30.12

GC content: 53.97

Gene sequence:

>252_bases
GTGAGCAATAAAGGTCAGCTTCTTCAAGACCCCTTCCTGAACGCCTTGCGTCGGGAGCATGTGCCGGTTTCGATTTATTT
GGTGAACGGCATCAAACTGCAGGGTCAAATCGAATCCTTCGATCAATACGTCGTGCTGCTGCGCAATACCGTGACGCAGA
TGGTGTACAAGCACGCCATTTCCACGATTGTGCCTGGTCGTGCCGTCAACTTCTCGACTGCGGAACCCGCCGCCGACGGG
GACAACCAATAA

Upstream 100 bases:

>100_bases
ATACGGACAAGCAGAACTCCTGAGCCCCTGGACGGCGTATGGCCGTCTGGCTGTGGTAAGGTGCTGGTTTACAACAACAT
TTTTGAACACGGAGAATATC

Downstream 100 bases:

>100_bases
GCCCCTGCGGCAGTTCAAGGCTGCGCCACGGCGCAAGCATTGCGCATCCCAGGGCACGCAGCCTTGAGTTCCCATTCTTC
TCCTGACACGAAATCCACGC

Product: RNA chaperone hfq

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 83; Mature: 82

Protein sequence:

>83_residues
MSNKGQLLQDPFLNALRREHVPVSIYLVNGIKLQGQIESFDQYVVLLRNTVTQMVYKHAISTIVPGRAVNFSTAEPAADG
DNQ

Sequences:

>Translated_83_residues
MSNKGQLLQDPFLNALRREHVPVSIYLVNGIKLQGQIESFDQYVVLLRNTVTQMVYKHAISTIVPGRAVNFSTAEPAADG
DNQ
>Mature_82_residues
SNKGQLLQDPFLNALRREHVPVSIYLVNGIKLQGQIESFDQYVVLLRNTVTQMVYKHAISTIVPGRAVNFSTAEPAADGD
NQ

Specific function: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs

COG id: COG1923

COG function: function code R; Uncharacterized host factor I protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hfq family

Homologues:

Organism=Escherichia coli, GI1790614, Length=67, Percent_Identity=85.0746268656716, Blast_Score=123, Evalue=3e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HFQ_ACIET (B9MFY1)

Other databases:

- EMBL:   CP001392
- RefSeq:   YP_002552572.1
- ProteinModelPortal:   B9MFY1
- SMR:   B9MFY1
- GeneID:   7382904
- GenomeReviews:   CP001392_GR
- KEGG:   dia:Dtpsy_1095
- ProtClustDB:   CLSK2471268
- HAMAP:   MF_00436
- InterPro:   IPR005001
- InterPro:   IPR010920
- InterPro:   IPR001163
- TIGRFAMs:   TIGR02383

Pfam domain/function: PF01423 LSM; SSF50182 Sm_like_riboprot

EC number: NA

Molecular weight: Translated: 9228; Mature: 9096

Theoretical pI: Translated: 7.70; Mature: 7.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNKGQLLQDPFLNALRREHVPVSIYLVNGIKLQGQIESFDQYVVLLRNTVTQMVYKHAI
CCCCCCCHHHHHHHHHHHCCCCEEEEEECCEEEECCHHHHHHHHHHHHHHHHHHHHHHHH
STIVPGRAVNFSTAEPAADGDNQ
HHHCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SNKGQLLQDPFLNALRREHVPVSIYLVNGIKLQGQIESFDQYVVLLRNTVTQMVYKHAI
CCCCCCHHHHHHHHHHHCCCCEEEEEECCEEEECCHHHHHHHHHHHHHHHHHHHHHHHH
STIVPGRAVNFSTAEPAADGDNQ
HHHCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA