Click here to switch to the map view.

The map label for this gene is hflX [H]

Identifier: 222110309

GI number: 222110309

Start: 1143868

End: 1145046

Strand: Direct

Name: hflX [H]

Synonym: Dtpsy_1096

Alternate gene names: 222110309

Gene position: 1143868-1145046 (Clockwise)

Preceding gene: 222110308

Following gene: 222110310

Centisome position: 30.13

GC content: 60.39

Gene sequence:

>1179_bases
TTGAGTTCCCATTCTTCTCCTGACACGAAATCCACGCCTGTTCTATTGGTAGGCGTGGATTTTGGTTTGCCCCATTTCGA
TGCCGAACTCGAAGAGCTTAGCTTATTGGCCCAGACTGCAGGCTTGAATCCTGTCGCGCGGCTGACGTGCAAGCGAAAGA
CGCCTGATGCGGCGCTGTTCGTGGGTAGCGGCAAAGCCGATGAGATCCGCACTCTGGCGCAGATGCATGGCGCGAAGGAG
GTGCTGTTCGACCAGGCGCTGAGTCCGGCGCAGCAGCGGAATCTGGAGCGAAGCCTGGAGTTGCCCGTCAATGATCGCAC
GCTGCTCATTCTGGAGATCTTTGCCCAGCGCGCCCGCAGCCACGAGGGCAAGCTGCAGGTGGAGTTGGCGCGTTTGCAGT
ACTTGAGCACTCGACTTGTGCGGCGCTGGTCGCACTTGGAGCGTCAACGCGGGGGGATTGGCACACGGGGCGGACCGGGC
GAAACACAAATTGAGCTCGACCGTCGCATGATCAGCGAAGCCATTAAGCGCACGCGGGAGCGCCTGGGCAAGGTCAAGCG
CCAACGGGCGACCCAGCGGCGGCAGCGGCAGCGGCGCGATACATTCAATATCTCGCTGGTGGGCTACACGAACGCGGGCA
AATCCACGCTGTTCAATGCACTGGTGAAGGCGCGAGCCTACGCAGCGGACCAGTTGTTCGCCACGCTGGACACCACCACG
CGTCATCTTTATTTGGGCGAAGCCGCGGGTTCGGTGTCCCTGTCCGATACCGTGGGCTTCATTCGTGATCTGCCGCACGG
GCTGGTGGATGCGTTTCAGGCCACGTTGCAGGAGGCCGTGGACGCGGATCTGCTCCTGCATGTGGTCGATGCCGCCAACC
CCGCCTTTCCCGAGCAGATTGCACAGGTGCAACTGGTTCTTGGTGAGATTGGCGCCGCCGATATTCCACAACTCTTGGTA
TTCAACAAATTGGATGCCCTCACGCCCGAAGTGCGTCCTAACGTGCGGCAAGATACCTATGAACTGGATGGGCGGCCTGT
ACCGCGGATTTTTGTCAGTGCCGGCCTTGGCGAAGGGGTGGCTGACTTGCGGCAGCTATTGGCAGACATGGTTCAGAAGT
CACTTTCGTCAGGCATGCCCCCTGAGACGGCGGCTGAATTGAAGGGCGAGTGGGACTGA

Upstream 100 bases:

>100_bases
GACTGCGGAACCCGCCGCCGACGGGGACAACCAATAAGCCCCTGCGGCAGTTCAAGGCTGCGCCACGGCGCAAGCATTGC
GCATCCCAGGGCACGCAGCC

Downstream 100 bases:

>100_bases
TTGGGCACAATGCTGGTGTTCTATTGCTATTGAGAGTACGAGAATTCGCGCATGAACCTTCTTAACCGGGCCTCTCGCTG
GGCCGTGCTGCCTGAGCGTA

Product: GTP-binding proten hflx

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 392; Mature: 391

Protein sequence:

>392_residues
MSSHSSPDTKSTPVLLVGVDFGLPHFDAELEELSLLAQTAGLNPVARLTCKRKTPDAALFVGSGKADEIRTLAQMHGAKE
VLFDQALSPAQQRNLERSLELPVNDRTLLILEIFAQRARSHEGKLQVELARLQYLSTRLVRRWSHLERQRGGIGTRGGPG
ETQIELDRRMISEAIKRTRERLGKVKRQRATQRRQRQRRDTFNISLVGYTNAGKSTLFNALVKARAYAADQLFATLDTTT
RHLYLGEAAGSVSLSDTVGFIRDLPHGLVDAFQATLQEAVDADLLLHVVDAANPAFPEQIAQVQLVLGEIGAADIPQLLV
FNKLDALTPEVRPNVRQDTYELDGRPVPRIFVSAGLGEGVADLRQLLADMVQKSLSSGMPPETAAELKGEWD

Sequences:

>Translated_392_residues
MSSHSSPDTKSTPVLLVGVDFGLPHFDAELEELSLLAQTAGLNPVARLTCKRKTPDAALFVGSGKADEIRTLAQMHGAKE
VLFDQALSPAQQRNLERSLELPVNDRTLLILEIFAQRARSHEGKLQVELARLQYLSTRLVRRWSHLERQRGGIGTRGGPG
ETQIELDRRMISEAIKRTRERLGKVKRQRATQRRQRQRRDTFNISLVGYTNAGKSTLFNALVKARAYAADQLFATLDTTT
RHLYLGEAAGSVSLSDTVGFIRDLPHGLVDAFQATLQEAVDADLLLHVVDAANPAFPEQIAQVQLVLGEIGAADIPQLLV
FNKLDALTPEVRPNVRQDTYELDGRPVPRIFVSAGLGEGVADLRQLLADMVQKSLSSGMPPETAAELKGEWD
>Mature_391_residues
SSHSSPDTKSTPVLLVGVDFGLPHFDAELEELSLLAQTAGLNPVARLTCKRKTPDAALFVGSGKADEIRTLAQMHGAKEV
LFDQALSPAQQRNLERSLELPVNDRTLLILEIFAQRARSHEGKLQVELARLQYLSTRLVRRWSHLERQRGGIGTRGGPGE
TQIELDRRMISEAIKRTRERLGKVKRQRATQRRQRQRRDTFNISLVGYTNAGKSTLFNALVKARAYAADQLFATLDTTTR
HLYLGEAAGSVSLSDTVGFIRDLPHGLVDAFQATLQEAVDADLLLHVVDAANPAFPEQIAQVQLVLGEIGAADIPQLLVF
NKLDALTPEVRPNVRQDTYELDGRPVPRIFVSAGLGEGVADLRQLLADMVQKSLSSGMPPETAAELKGEWD

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133118, Length=250, Percent_Identity=37.2, Blast_Score=115, Evalue=9e-26,
Organism=Homo sapiens, GI310133116, Length=245, Percent_Identity=37.1428571428571, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI310124269, Length=224, Percent_Identity=37.5, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI310124267, Length=224, Percent_Identity=37.5, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI310124171, Length=224, Percent_Identity=37.5, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI310124169, Length=224, Percent_Identity=37.5, Blast_Score=112, Evalue=6e-25,
Organism=Escherichia coli, GI1790615, Length=371, Percent_Identity=50.9433962264151, Blast_Score=327, Evalue=7e-91,
Organism=Caenorhabditis elegans, GI17561038, Length=234, Percent_Identity=35.4700854700855, Blast_Score=123, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24650079, Length=339, Percent_Identity=33.0383480825959, Blast_Score=117, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 43190; Mature: 43059

Theoretical pI: Translated: 7.83; Mature: 7.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSHSSPDTKSTPVLLVGVDFGLPHFDAELEELSLLAQTAGLNPVARLTCKRKTPDAALF
CCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCHHHHHEECCCCCCCEEE
VGSGKADEIRTLAQMHGAKEVLFDQALSPAQQRNLERSLELPVNDRTLLILEIFAQRARS
ECCCCHHHHHHHHHHHCHHHHHHHHHCCHHHHHCCHHHCCCCCCCCHHHHHHHHHHHHHC
HEGKLQVELARLQYLSTRLVRRWSHLERQRGGIGTRGGPGETQIELDRRMISEAIKRTRE
CCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
RLGKVKRQRATQRRQRQRRDTFNISLVGYTNAGKSTLFNALVKARAYAADQLFATLDTTT
HHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCH
RHLYLGEAAGSVSLSDTVGFIRDLPHGLVDAFQATLQEAVDADLLLHVVDAANPAFPEQI
HEEEEECCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
AQVQLVLGEIGAADIPQLLVFNKLDALTPEVRPNVRQDTYELDGRPVPRIFVSAGLGEGV
HHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCCCCHHHEECCCCCCH
ADLRQLLADMVQKSLSSGMPPETAAELKGEWD
HHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCC
>Mature Secondary Structure 
SSHSSPDTKSTPVLLVGVDFGLPHFDAELEELSLLAQTAGLNPVARLTCKRKTPDAALF
CCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCHHHHHEECCCCCCCEEE
VGSGKADEIRTLAQMHGAKEVLFDQALSPAQQRNLERSLELPVNDRTLLILEIFAQRARS
ECCCCHHHHHHHHHHHCHHHHHHHHHCCHHHHHCCHHHCCCCCCCCHHHHHHHHHHHHHC
HEGKLQVELARLQYLSTRLVRRWSHLERQRGGIGTRGGPGETQIELDRRMISEAIKRTRE
CCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
RLGKVKRQRATQRRQRQRRDTFNISLVGYTNAGKSTLFNALVKARAYAADQLFATLDTTT
HHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCH
RHLYLGEAAGSVSLSDTVGFIRDLPHGLVDAFQATLQEAVDADLLLHVVDAANPAFPEQI
HEEEEECCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
AQVQLVLGEIGAADIPQLLVFNKLDALTPEVRPNVRQDTYELDGRPVPRIFVSAGLGEGV
HHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCCCCHHHEECCCCCCH
ADLRQLLADMVQKSLSSGMPPETAAELKGEWD
HHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]