Click here to switch to the map view.

The map label for this gene is engA

Identifier: 222110307

GI number: 222110307

Start: 1142132

End: 1143475

Strand: Direct

Name: engA

Synonym: Dtpsy_1094

Alternate gene names: 222110307

Gene position: 1142132-1143475 (Clockwise)

Preceding gene: 222110306

Following gene: 222110308

Centisome position: 30.08

GC content: 60.64

Gene sequence:

>1344_bases
ATGAAGCCTGTCATCGCTTTGGTGGGGCGGCCCAATGTGGGCAAGTCCACCTTGTTCAACCGTTTGACCAAGTCGCGCGA
TGCGATCGTGGCCGACTTTGCCGGCCTCACACGTGATCGCCACTATGGCAATGGGAGACAGGGCAAGCACGAGTACATCG
TCATCGATACCGGGGGGTTCGAGCCCGACGCCTCCAGCGGCATCTACCGCGAGATGGCCAGGCAGACCCAGCAGGCCGTG
GCGGAGGCCGATGTCGTGGTTTTTGTCGTGGACGTACGCGGCGGACTGTCCGCCCAGGACCACGACATTGCCAACTACCT
TCGCCGCCTGGGCAAACCCTGCGTGTTGGCAGGCAACAAGGCCGAAGGCATGCAGGACAGCATGCATCTGGCCGAGTTCT
ATGAGTTGGGCCTGGGAGAGGTGCACCCCGTATCGGCGGCGCACGGCCAGGGTGTGCGCAGCCTGGTGGATCTCGCGCTG
AAGCCGCTCGCGTTGCCCGAGATTGAGGAGGAGGATGCGGCGGCCGAGAAGAATGTCATCCGTCTTGCAGTGGCAGGGCG
CCCCAACGTGGGCAAGTCGACACTGATCAATACATGGCTGGGTGAAGAGCGTTTGGTGGCTTTCGACATGCCCGGCACCA
CGCGCGATGCCATATCGGTGCCTTTCGAGCGCAACGGCCAGAAGTTCGAATTGATCGACACGGCGGGCCTGCGACGCAAA
GGCAAGGTGTTTGAAGCGATCGAGAAATTCTCGGTCGTGAAGACCCTGCAGGCCATCGAGTCAGCCAATGTCGTGCTGCT
GCTGCTGGACGCCACGCAGGGAGTGACGGACCAGGACGCACATATTGCCGGCTACATCCTGGAGAGTGGTCGCGCCGTGG
TGATCGCAGTGAACAAATGGGATGCGGTGGACGACTATGGCCGGCAGCAGCTGGAGCGTTCCATCGAAACGCGTCTGTCG
TTTCTAAAGTTCGCGCCGTTGCACTTCATCTCCGCGAAGAAACGGCAGGGCATTGGGCCGCTGTGGTCATCCATCATCCA
GGCGTACAAGTCTGCCAACCGCAAGATGCCTACGCCGGTGTTGACGCGCCTGCTGCAGGAGGCGGTGCAGTTCCAAAGCC
CCAAGCGCTCGGGTATGTTCCGGCCCAAGATGCGCTATGCGCACCAGGGCGGCATGAATCCGCCGGTGATCGTGATCCAC
GGGAATTCGCTGGAGCATGTAACGGACGCCTACAAGCGCTTTCTTGAGGCGCGTTTTCGCAAAGAATTTGACCTCGTCGG
TACGCCGCTGCGTATCGAAATGAAAACCTCCAGCAATCCTTATACGGACAAGCAGAACTCCTGA

Upstream 100 bases:

>100_bases
GCGGCGGCCCCGGCGGTGGCGGGCGACACCTTGGTGGTGGTGACGCGCAAGGGCGGCGTCTACGGCTTCCGTCCGGACTG
ATAGGGATATAGGACACAGG

Downstream 100 bases:

>100_bases
GCCCCTGGACGGCGTATGGCCGTCTGGCTGTGGTAAGGTGCTGGTTTACAACAACATTTTTGAACACGGAGAATATCGTG
AGCAATAAAGGTCAGCTTCT

Product: GTP-binding protein enga

Products: NA

Alternate protein names: GTP-binding protein EngA

Number of amino acids: Translated: 447; Mature: 447

Protein sequence:

>447_residues
MKPVIALVGRPNVGKSTLFNRLTKSRDAIVADFAGLTRDRHYGNGRQGKHEYIVIDTGGFEPDASSGIYREMARQTQQAV
AEADVVVFVVDVRGGLSAQDHDIANYLRRLGKPCVLAGNKAEGMQDSMHLAEFYELGLGEVHPVSAAHGQGVRSLVDLAL
KPLALPEIEEEDAAAEKNVIRLAVAGRPNVGKSTLINTWLGEERLVAFDMPGTTRDAISVPFERNGQKFELIDTAGLRRK
GKVFEAIEKFSVVKTLQAIESANVVLLLLDATQGVTDQDAHIAGYILESGRAVVIAVNKWDAVDDYGRQQLERSIETRLS
FLKFAPLHFISAKKRQGIGPLWSSIIQAYKSANRKMPTPVLTRLLQEAVQFQSPKRSGMFRPKMRYAHQGGMNPPVIVIH
GNSLEHVTDAYKRFLEARFRKEFDLVGTPLRIEMKTSSNPYTDKQNS

Sequences:

>Translated_447_residues
MKPVIALVGRPNVGKSTLFNRLTKSRDAIVADFAGLTRDRHYGNGRQGKHEYIVIDTGGFEPDASSGIYREMARQTQQAV
AEADVVVFVVDVRGGLSAQDHDIANYLRRLGKPCVLAGNKAEGMQDSMHLAEFYELGLGEVHPVSAAHGQGVRSLVDLAL
KPLALPEIEEEDAAAEKNVIRLAVAGRPNVGKSTLINTWLGEERLVAFDMPGTTRDAISVPFERNGQKFELIDTAGLRRK
GKVFEAIEKFSVVKTLQAIESANVVLLLLDATQGVTDQDAHIAGYILESGRAVVIAVNKWDAVDDYGRQQLERSIETRLS
FLKFAPLHFISAKKRQGIGPLWSSIIQAYKSANRKMPTPVLTRLLQEAVQFQSPKRSGMFRPKMRYAHQGGMNPPVIVIH
GNSLEHVTDAYKRFLEARFRKEFDLVGTPLRIEMKTSSNPYTDKQNS
>Mature_447_residues
MKPVIALVGRPNVGKSTLFNRLTKSRDAIVADFAGLTRDRHYGNGRQGKHEYIVIDTGGFEPDASSGIYREMARQTQQAV
AEADVVVFVVDVRGGLSAQDHDIANYLRRLGKPCVLAGNKAEGMQDSMHLAEFYELGLGEVHPVSAAHGQGVRSLVDLAL
KPLALPEIEEEDAAAEKNVIRLAVAGRPNVGKSTLINTWLGEERLVAFDMPGTTRDAISVPFERNGQKFELIDTAGLRRK
GKVFEAIEKFSVVKTLQAIESANVVLLLLDATQGVTDQDAHIAGYILESGRAVVIAVNKWDAVDDYGRQQLERSIETRLS
FLKFAPLHFISAKKRQGIGPLWSSIIQAYKSANRKMPTPVLTRLLQEAVQFQSPKRSGMFRPKMRYAHQGGMNPPVIVIH
GNSLEHVTDAYKRFLEARFRKEFDLVGTPLRIEMKTSSNPYTDKQNS

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain

Homologues:

Organism=Escherichia coli, GI87082120, Length=471, Percent_Identity=49.2569002123142, Blast_Score=467, Evalue=1e-133,
Organism=Escherichia coli, GI1788919, Length=168, Percent_Identity=32.1428571428571, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI2367268, Length=93, Percent_Identity=37.6344086021505, Blast_Score=70, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6323665, Length=185, Percent_Identity=31.3513513513514, Blast_Score=87, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DER_ACIET (B9MFY0)

Other databases:

- EMBL:   CP001392
- RefSeq:   YP_002552571.1
- GeneID:   7382903
- GenomeReviews:   CP001392_GR
- KEGG:   dia:Dtpsy_1094
- ProtClustDB:   PRK00093
- GO:   GO:0005622
- HAMAP:   MF_00195
- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:3.30.300.20
- PIRSF:   PIRSF006485
- PRINTS:   PR00326
- TIGRFAMs:   TIGR03594
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF01926 MMR_HSR1

EC number: NA

Molecular weight: Translated: 49458; Mature: 49458

Theoretical pI: Translated: 9.70; Mature: 9.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPVIALVGRPNVGKSTLFNRLTKSRDAIVADFAGLTRDRHYGNGRQGKHEYIVIDTGGF
CCCEEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCC
EPDASSGIYREMARQTQQAVAEADVVVFVVDVRGGLSAQDHDIANYLRRLGKPCVLAGNK
CCCCCCHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCCHHHHHHHHHHCCCEEEECCC
AEGMQDSMHLAEFYELGLGEVHPVSAAHGQGVRSLVDLALKPLALPEIEEEDAAAEKNVI
CCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHCCCEE
RLAVAGRPNVGKSTLINTWLGEERLVAFDMPGTTRDAISVPFERNGQKFELIDTAGLRRK
EEEECCCCCCCHHHHHHHHCCCCEEEEEECCCCCCCCEECCCCCCCCEEEEEECCCCCCC
GKVFEAIEKFSVVKTLQAIESANVVLLLLDATQGVTDQDAHIAGYILESGRAVVIAVNKW
CHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCEEEEEEECCCEEEEEECCC
DAVDDYGRQQLERSIETRLSFLKFAPLHFISAKKRQGIGPLWSSIIQAYKSANRKMPTPV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCHH
LTRLLQEAVQFQSPKRSGMFRPKMRYAHQGGMNPPVIVIHGNSLEHVTDAYKRFLEARFR
HHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHH
KEFDLVGTPLRIEMKTSSNPYTDKQNS
HHHHCCCCCEEEEEECCCCCCCCCCCC
>Mature Secondary Structure
MKPVIALVGRPNVGKSTLFNRLTKSRDAIVADFAGLTRDRHYGNGRQGKHEYIVIDTGGF
CCCEEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCC
EPDASSGIYREMARQTQQAVAEADVVVFVVDVRGGLSAQDHDIANYLRRLGKPCVLAGNK
CCCCCCHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCCHHHHHHHHHHCCCEEEECCC
AEGMQDSMHLAEFYELGLGEVHPVSAAHGQGVRSLVDLALKPLALPEIEEEDAAAEKNVI
CCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHCCCEE
RLAVAGRPNVGKSTLINTWLGEERLVAFDMPGTTRDAISVPFERNGQKFELIDTAGLRRK
EEEECCCCCCCHHHHHHHHCCCCEEEEEECCCCCCCCEECCCCCCCCEEEEEECCCCCCC
GKVFEAIEKFSVVKTLQAIESANVVLLLLDATQGVTDQDAHIAGYILESGRAVVIAVNKW
CHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCEEEEEEECCCEEEEEECCC
DAVDDYGRQQLERSIETRLSFLKFAPLHFISAKKRQGIGPLWSSIIQAYKSANRKMPTPV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCHH
LTRLLQEAVQFQSPKRSGMFRPKMRYAHQGGMNPPVIVIHGNSLEHVTDAYKRFLEARFR
HHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHH
KEFDLVGTPLRIEMKTSSNPYTDKQNS
HHHHCCCCCEEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA