BacMap

Definition	Acidovorax ebreus TPSY chromosome, complete genome.
Accession	NC_011992
Length	3,796,573

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The map label for this gene is paaG [H]

Identifier: 222109361

GI number: 222109361

Start: 157389

End: 158183

Strand: Direct

Name: paaG [H]

Synonym: Dtpsy_0140

Alternate gene names: 222109361

Gene position: 157389-158183 (Clockwise)

Preceding gene: 222109360

Following gene: 222109362

Centisome position: 4.15

GC content: 68.18

Gene sequence:

>795_bases
ATGAGCGCATCCCCCGTGTTGACCTCCGTGCAGGACGGCATCGGCACCATCACCCTGAACCGCCCCGAGGCACGCAACGC
GCTCAACCAGGCCATGCGCCCGGCCCTGGCCGCCGCCATCGCGCAGATGCGCGACGACGCGCAGGTGCACGCGGTCATCC
TCACCGGCGCGGGCGGCGCGTTCTGCTCGGGCGGCGACATCTCTGCCATGCTGGACACCAGCCGCACCGGCCTGGCCTTT
CGCAAGGGCATGCGCGAGCTGCACCAGTGGTTCCCCGAACTCGTGAACCTGGAAAAGCCCGTGATCGCCGCGGTGGACGG
CCCAGCCTTCGGCGCGGGCCTGAGCCTGGCGCTGGCAGCCGACTTCGTGCTGGCCACGCGCCGCGCCAAGTTCTGCGCGG
TGTTCGGCCGCATTGGCCTGATCCCCGACCTGGGCGCGATGCACCTGCTGCCGCGCATCGTGGGCCAGCAAAAGGCCAAG
GAGCTGGTCTTCACCGCGCGCACCGTCGATGCCGAAGAAGCCCAGCAACTGGGCATGGTGTTCGACATTGTGGACGACGC
CACCGCGTTGACCGAGGCCGCGTTGGCGCTGGCACGGCGTTTTGGCGAGGCCTCCACCGCTGCCATCGGCATGGCCAAGA
CCATCATGAACCAGTCCTTCGAGAGCGACGCGCGCACCATCGCCGAGCTGGAGTCCTATGCGCAATCTGTGTGCCGTGGC
TCCGACTACCACCAGGACGCGGTGCGACGGTTCAAGGACAAGCAGCCGCTGCGCTTCGACTGGGACAGGAAATGA

Upstream 100 bases:

>100_bases
CGGCTTCGCCGAACTGGCGTGAGCTATCAAAAAGTGAGCTGTCGGCGCTTCATAGGTAAGCGCTGGAGCTCGTTCTGAAT
CAAATACCCTGGAGCACGCC

Downstream 100 bases:

>100_bases
CTCCCCCCTGTGTCGCCTGCGGCGCCATCCCCCCAGGGGGACGACGCCAGTGGCCGGGCAAAGCCCGCACCACGGCGTCC
GCTGGCATGGCCTGCTCCGC

Product: enoyl-CoA hydratase/isomerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 264; Mature: 263

Protein sequence:

>264_residues
MSASPVLTSVQDGIGTITLNRPEARNALNQAMRPALAAAIAQMRDDAQVHAVILTGAGGAFCSGGDISAMLDTSRTGLAF
RKGMRELHQWFPELVNLEKPVIAAVDGPAFGAGLSLALAADFVLATRRAKFCAVFGRIGLIPDLGAMHLLPRIVGQQKAK
ELVFTARTVDAEEAQQLGMVFDIVDDATALTEAALALARRFGEASTAAIGMAKTIMNQSFESDARTIAELESYAQSVCRG
SDYHQDAVRRFKDKQPLRFDWDRK

Sequences:

>Translated_264_residues
MSASPVLTSVQDGIGTITLNRPEARNALNQAMRPALAAAIAQMRDDAQVHAVILTGAGGAFCSGGDISAMLDTSRTGLAF
RKGMRELHQWFPELVNLEKPVIAAVDGPAFGAGLSLALAADFVLATRRAKFCAVFGRIGLIPDLGAMHLLPRIVGQQKAK
ELVFTARTVDAEEAQQLGMVFDIVDDATALTEAALALARRFGEASTAAIGMAKTIMNQSFESDARTIAELESYAQSVCRG
SDYHQDAVRRFKDKQPLRFDWDRK
>Mature_263_residues
SASPVLTSVQDGIGTITLNRPEARNALNQAMRPALAAAIAQMRDDAQVHAVILTGAGGAFCSGGDISAMLDTSRTGLAFR
KGMRELHQWFPELVNLEKPVIAAVDGPAFGAGLSLALAADFVLATRRAKFCAVFGRIGLIPDLGAMHLLPRIVGQQKAKE
LVFTARTVDAEEAQQLGMVFDIVDDATALTEAALALARRFGEASTAAIGMAKTIMNQSFESDARTIAELESYAQSVCRGS
DYHQDAVRRFKDKQPLRFDWDRK

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=249, Percent_Identity=33.3333333333333, Blast_Score=121, Evalue=6e-28,
Organism=Homo sapiens, GI4502327, Length=255, Percent_Identity=32.9411764705882, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI70995211, Length=256, Percent_Identity=30.859375, Blast_Score=99, Evalue=4e-21,
Organism=Homo sapiens, GI45643119, Length=216, Percent_Identity=29.6296296296296, Blast_Score=95, Evalue=8e-20,
Organism=Homo sapiens, GI260275230, Length=216, Percent_Identity=29.6296296296296, Blast_Score=95, Evalue=8e-20,
Organism=Homo sapiens, GI260274832, Length=219, Percent_Identity=30.1369863013699, Blast_Score=95, Evalue=8e-20,
Organism=Homo sapiens, GI37594471, Length=157, Percent_Identity=31.8471337579618, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI37594469, Length=157, Percent_Identity=31.8471337579618, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI157694516, Length=189, Percent_Identity=31.2169312169312, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI213417737, Length=189, Percent_Identity=31.2169312169312, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI221136756, Length=253, Percent_Identity=24.5059288537549, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI221136753, Length=253, Percent_Identity=24.5059288537549, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI221307494, Length=253, Percent_Identity=24.5059288537549, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI31542718, Length=224, Percent_Identity=27.6785714285714, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI68989263, Length=193, Percent_Identity=29.0155440414508, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI116235487, Length=257, Percent_Identity=22.9571984435798, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI4757968, Length=263, Percent_Identity=25.0950570342205, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI49355787, Length=263, Percent_Identity=25.0950570342205, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI20127408, Length=182, Percent_Identity=25.8241758241758, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI25453481, Length=196, Percent_Identity=25.5102040816327, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI51538573, Length=196, Percent_Identity=25.5102040816327, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI4757966, Length=196, Percent_Identity=25.5102040816327, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI51538581, Length=196, Percent_Identity=25.5102040816327, Blast_Score=74, Evalue=1e-13,
Organism=Escherichia coli, GI1787660, Length=244, Percent_Identity=38.5245901639344, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI221142681, Length=264, Percent_Identity=34.8484848484849, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1787659, Length=218, Percent_Identity=34.4036697247706, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI1788597, Length=251, Percent_Identity=30.6772908366534, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1790281, Length=201, Percent_Identity=30.3482587064677, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI1788682, Length=206, Percent_Identity=32.0388349514563, Blast_Score=84, Evalue=7e-18,
Organism=Escherichia coli, GI87082183, Length=267, Percent_Identity=23.2209737827715, Blast_Score=77, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17540714, Length=233, Percent_Identity=33.4763948497854, Blast_Score=115, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17536985, Length=241, Percent_Identity=29.045643153527, Blast_Score=110, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI17560910, Length=196, Percent_Identity=32.1428571428571, Blast_Score=102, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17534483, Length=220, Percent_Identity=29.0909090909091, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI25145438, Length=226, Percent_Identity=32.3008849557522, Blast_Score=101, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17554946, Length=211, Percent_Identity=32.7014218009479, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17549921, Length=262, Percent_Identity=28.6259541984733, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17535521, Length=182, Percent_Identity=27.4725274725275, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI25144160, Length=160, Percent_Identity=28.75, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI25144157, Length=160, Percent_Identity=28.75, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17558304, Length=174, Percent_Identity=25.2873563218391, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17508953, Length=174, Percent_Identity=27.5862068965517, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI25144276, Length=178, Percent_Identity=26.9662921348315, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17508951, Length=174, Percent_Identity=27.5862068965517, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17540306, Length=195, Percent_Identity=28.2051282051282, Blast_Score=64, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6320241, Length=217, Percent_Identity=30.8755760368664, Blast_Score=92, Evalue=7e-20,
Organism=Drosophila melanogaster, GI20129971, Length=248, Percent_Identity=31.4516129032258, Blast_Score=126, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24653477, Length=248, Percent_Identity=31.4516129032258, Blast_Score=126, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24653139, Length=240, Percent_Identity=32.5, Blast_Score=108, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24654903, Length=202, Percent_Identity=27.7227722772277, Blast_Score=101, Evalue=5e-22,
Organism=Drosophila melanogaster, GI19920382, Length=216, Percent_Identity=29.6296296296296, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI21357171, Length=189, Percent_Identity=31.7460317460317, Blast_Score=88, Evalue=5e-18,
Organism=Drosophila melanogaster, GI28571730, Length=156, Percent_Identity=32.6923076923077, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI28571729, Length=156, Percent_Identity=32.6923076923077, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24650670, Length=269, Percent_Identity=27.5092936802974, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI19922422, Length=210, Percent_Identity=25.7142857142857, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001753
- InterPro:   IPR011968 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 28380; Mature: 28249

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSASPVLTSVQDGIGTITLNRPEARNALNQAMRPALAAAIAQMRDDAQVHAVILTGAGGA
CCCCCCHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCC
FCSGGDISAMLDTSRTGLAFRKGMRELHQWFPELVNLEKPVIAAVDGPAFGAGLSLALAA
CCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHH
DFVLATRRAKFCAVFGRIGLIPDLGAMHLLPRIVGQQKAKELVFTARTVDAEEAQQLGMV
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
FDIVDDATALTEAALALARRFGEASTAAIGMAKTIMNQSFESDARTIAELESYAQSVCRG
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SDYHQDAVRRFKDKQPLRFDWDRK
CCCHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
SASPVLTSVQDGIGTITLNRPEARNALNQAMRPALAAAIAQMRDDAQVHAVILTGAGGA
CCCCCHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCC
FCSGGDISAMLDTSRTGLAFRKGMRELHQWFPELVNLEKPVIAAVDGPAFGAGLSLALAA
CCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHH
DFVLATRRAKFCAVFGRIGLIPDLGAMHLLPRIVGQQKAKELVFTARTVDAEEAQQLGMV
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
FDIVDDATALTEAALALARRFGEASTAAIGMAKTIMNQSFESDARTIAELESYAQSVCRG
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SDYHQDAVRRFKDKQPLRFDWDRK
CCCHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9748275; 9097039; 9278503; 10766858 [H]