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The map label for this gene is 222109360

Identifier: 222109360

GI number: 222109360

Start: 156417

End: 157310

Strand: Direct

Name: 222109360

Synonym: Dtpsy_0139

Alternate gene names: NA

Gene position: 156417-157310 (Clockwise)

Preceding gene: 222109359

Following gene: 222109361

Centisome position: 4.12

GC content: 72.04

Gene sequence:

>894_bases
ATGGCCATTGACTATCACCACCTGAAGGCGCGCGATTTTGGCGTGATCCGCCAGACGTACACCGAGCGCGACACCATGCT
TTACGCGCTCAGCCTCGGGCTGGGCAACGATCCGCTGAACGCCAGCGCGCTGCCCTTCGTCTACGAGGGGCTGGAAGGCG
GCCTGCGCGCCCTGCCGTCGCAGGCCGTGGTGCTGGGCTACCCGGGCTTCTGGGCGCGCGAGCCGGACACGGGCATCGAC
TGGGTCAAGCTCCTGCACGGCGAGCAGCGCATGCGCCTGCACCGCCCGCTGCCCGCGAGCGGCGAGGTCGTGGGCCACAA
CCGCATCACGCACCTGACCGACAAGGGCGAGGGCAAGGGCGCCATCATGGTGACCGAGCGGCGCCTGGAAACCGCCGCCG
GCGAGCTGCTGGCCACCGTGCAGCAGGTGACCTTTCTGCGCGGGGATGGCGGCTACAGCCAGCAGGGCGGCGGCCAGCCC
AGCGACGCACCGCTGCCCGCGCTGCAGCCCACGCCGCAGGACCGCGCGCCCGACTTCACCGACACCCAGCCCACCCGCCC
CGAGGCGGCGCTGCTCTACCGCCTGATGGGCGACTACAACCCGCTGCACGCCGACCCGGCCGTGGCCGCCAAGGCCGGCT
TCGAGCGCCCCATCCTGCACGGGCTGGCCAGCTACGGCCTGGTGGCGCATGCGGTGTTGCGCCAGTGCTGCGCCGGCGAT
CCCGCGCGCCTCAAGGCGATGGACATCCGCTTCGCCGCCCCGGTGTACCCGGGCGAGACGTTGGTGACCGAGATCTGGCG
CGTGCCCGGCCAACCGGCGCAGGTGCAGCTGCGCGCCCGTGTGCTCGAACGCGACAAGGTGGTGCTGAGCCACGGCTTCG
CCGAACTGGCGTGA

Upstream 100 bases:

>100_bases
GGGCGGCGCGGCCAGCCCAGGCCCTTGCGCGGTGGCCGCTGGCCTGGGGACGCGCCAGTTGCATGGCGCGCTGGCAATCA
CAACCTTATGGACAACTGAG

Downstream 100 bases:

>100_bases
GCTATCAAAAAGTGAGCTGTCGGCGCTTCATAGGTAAGCGCTGGAGCTCGTTCTGAATCAAATACCCTGGAGCACGCCAT
GAGCGCATCCCCCGTGTTGA

Product: 3-alpha,7-alpha, 12-alpha-trihydroxy-5-beta-cholest-24-enoyl-coahydratase

Products: NA

Alternate protein names: 3-Alpha 7-Alpha; MaoC-Like Dehydratase; Dehydrogenase; Acyl Dehydratase; UfaA2 Protein; MaoC-Like Domain-Containing; Enoyl-CoA Hydratase; Short-Chain Dehydrogenase/Reductase SDR; MaoC Family Protein; Hydratase; -Specific Enoyl-CoA Hydratase; 2-Enoyl Acyl-CoA Hydratase; MaoC Acyl Dehydratase; MaoC Domain-Containing Protein Dehydratase; MaoC Family Dehydratase; Enoyl-CoA Hydratase/3-Hydroxyacyl-CoA Dehydratase; MaoC Like Dehydratase/Enoyl-CoA Hydratase; MaoC-Like-Specific Enoyl-CoA Hydratase; MaoC-Like Domain-Containing Protein; MaoC Family Dehydrogenase/Dehydratase; MaoC Like Domain Protein

Number of amino acids: Translated: 297; Mature: 296

Protein sequence:

>297_residues
MAIDYHHLKARDFGVIRQTYTERDTMLYALSLGLGNDPLNASALPFVYEGLEGGLRALPSQAVVLGYPGFWAREPDTGID
WVKLLHGEQRMRLHRPLPASGEVVGHNRITHLTDKGEGKGAIMVTERRLETAAGELLATVQQVTFLRGDGGYSQQGGGQP
SDAPLPALQPTPQDRAPDFTDTQPTRPEAALLYRLMGDYNPLHADPAVAAKAGFERPILHGLASYGLVAHAVLRQCCAGD
PARLKAMDIRFAAPVYPGETLVTEIWRVPGQPAQVQLRARVLERDKVVLSHGFAELA

Sequences:

>Translated_297_residues
MAIDYHHLKARDFGVIRQTYTERDTMLYALSLGLGNDPLNASALPFVYEGLEGGLRALPSQAVVLGYPGFWAREPDTGID
WVKLLHGEQRMRLHRPLPASGEVVGHNRITHLTDKGEGKGAIMVTERRLETAAGELLATVQQVTFLRGDGGYSQQGGGQP
SDAPLPALQPTPQDRAPDFTDTQPTRPEAALLYRLMGDYNPLHADPAVAAKAGFERPILHGLASYGLVAHAVLRQCCAGD
PARLKAMDIRFAAPVYPGETLVTEIWRVPGQPAQVQLRARVLERDKVVLSHGFAELA
>Mature_296_residues
AIDYHHLKARDFGVIRQTYTERDTMLYALSLGLGNDPLNASALPFVYEGLEGGLRALPSQAVVLGYPGFWAREPDTGIDW
VKLLHGEQRMRLHRPLPASGEVVGHNRITHLTDKGEGKGAIMVTERRLETAAGELLATVQQVTFLRGDGGYSQQGGGQPS
DAPLPALQPTPQDRAPDFTDTQPTRPEAALLYRLMGDYNPLHADPAVAAKAGFERPILHGLASYGLVAHAVLRQCCAGDP
ARLKAMDIRFAAPVYPGETLVTEIWRVPGQPAQVQLRARVLERDKVVLSHGFAELA

Specific function: Unknown

COG id: COG2030

COG function: function code I; Acyl dehydratase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI4504505, Length=283, Percent_Identity=38.86925795053, Blast_Score=177, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI17532783, Length=283, Percent_Identity=36.3957597173145, Blast_Score=158, Evalue=4e-39,
Organism=Saccharomyces cerevisiae, GI6322861, Length=299, Percent_Identity=30.4347826086957, Blast_Score=104, Evalue=2e-23,
Organism=Drosophila melanogaster, GI18859837, Length=287, Percent_Identity=35.5400696864112, Blast_Score=164, Evalue=5e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 32350; Mature: 32219

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIDYHHLKARDFGVIRQTYTERDTMLYALSLGLGNDPLNASALPFVYEGLEGGLRALPS
CCCCCCHHCHHHHHHHHHHHHHHHEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCC
QAVVLGYPGFWAREPDTGIDWVKLLHGEQRMRLHRPLPASGEVVGHNRITHLTDKGEGKG
CEEEEECCCCCCCCCCCCHHHHHHHHCHHHHHHCCCCCCCCCEECCCCEEEECCCCCCCE
AIMVTERRLETAAGELLATVQQVTFLRGDGGYSQQGGGQPSDAPLPALQPTPQDRAPDFT
EEEEEHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
DTQPTRPEAALLYRLMGDYNPLHADPAVAAKAGFERPILHGLASYGLVAHAVLRQCCAGD
CCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
PARLKAMDIRFAAPVYPGETLVTEIWRVPGQPAQVQLRARVLERDKVVLSHGFAELA
HHHEEEEEEEEECCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHCC
>Mature Secondary Structure 
AIDYHHLKARDFGVIRQTYTERDTMLYALSLGLGNDPLNASALPFVYEGLEGGLRALPS
CCCCCHHCHHHHHHHHHHHHHHHEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCC
QAVVLGYPGFWAREPDTGIDWVKLLHGEQRMRLHRPLPASGEVVGHNRITHLTDKGEGKG
CEEEEECCCCCCCCCCCCHHHHHHHHCHHHHHHCCCCCCCCCEECCCCEEEECCCCCCCE
AIMVTERRLETAAGELLATVQQVTFLRGDGGYSQQGGGQPSDAPLPALQPTPQDRAPDFT
EEEEEHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
DTQPTRPEAALLYRLMGDYNPLHADPAVAAKAGFERPILHGLASYGLVAHAVLRQCCAGD
CCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
PARLKAMDIRFAAPVYPGETLVTEIWRVPGQPAQVQLRARVLERDKVVLSHGFAELA
HHHEEEEEEEEECCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA