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The map label for this gene is leuE [H]

Identifier: 222109272

GI number: 222109272

Start: 51110

End: 51724

Strand: Direct

Name: leuE [H]

Synonym: Dtpsy_0047

Alternate gene names: 222109272

Gene position: 51110-51724 (Clockwise)

Preceding gene: 222109271

Following gene: 222109273

Centisome position: 1.35

GC content: 66.67

Gene sequence:

>615_bases
ATGTTCGGCATTGCAGACTACGGCGCATTCGTCGCCGCCATCGTGTTGTTCCTCGCCATCCCGGGGCCGGGCAATCTGGC
GCTCATCACTTCCACCGGCAAGGGCGGTGTGCGCGCCGGCATGGCCGCCTGCATGGGCGTGATCGCCGCCGACCAGGTGC
TCATGTGGATGGCGGTGGCCGGCGTGGCGGGCCTGCTGGCCGCGTATCCGGCGGCATTCCATGCCGTGCAATGGCTAGGC
GCCGTCTACCTGGGCTGGATGGGCTACAAGATGCTCACCGCCAAGCCGGGGGATGCGCCGGTGCTGAACATCGCGCCGCG
CCACTACTTCCGCCAGGGGGCGGTCATCACGCTGCTCAACCCCAAGGCCATCGTGTTCTACATGGCCTTCTTCCCGCTGT
TCGTGAACCCGGCCACGCACCGCGGGTTGGTCACCTTCGCCGCCATGGCCGCCACCATCGCCACGCTCACCTTCCTGTAC
AGCCTGGTTGTGGTGCTGCTCACGCACTTCCTGGCCGAGCGCATGCGCGCCAACCCCACGGTGGCGCGCGTGTTGGAGAA
AACGGCGGGCGTGTTCCTCATCGGCTTCGGCGTCAAGCTGGCCATTTCCAAGTAA

Upstream 100 bases:

>100_bases
GAACAACTCACTGTGCCGGGCCTGCAGGCCGAACGCTGCATCCTCTGGCTGCGCCCCGTCGCGTAAACTCAAGCCCCCTC
CCGCTTCGCAAGGCGCTCCC

Downstream 100 bases:

>100_bases
TCGCGAATTGCCCCGCATGGCCAAGATCTTCTGCATTGCCAACCAAAAGGGTGGGGTCGGCAAGACCACCACTTCCGTCA
ATCTGGCCGCGGGCCTGGCC

Product: lysine exporter protein LysE/YggA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 204; Mature: 204

Protein sequence:

>204_residues
MFGIADYGAFVAAIVLFLAIPGPGNLALITSTGKGGVRAGMAACMGVIAADQVLMWMAVAGVAGLLAAYPAAFHAVQWLG
AVYLGWMGYKMLTAKPGDAPVLNIAPRHYFRQGAVITLLNPKAIVFYMAFFPLFVNPATHRGLVTFAAMAATIATLTFLY
SLVVVLLTHFLAERMRANPTVARVLEKTAGVFLIGFGVKLAISK

Sequences:

>Translated_204_residues
MFGIADYGAFVAAIVLFLAIPGPGNLALITSTGKGGVRAGMAACMGVIAADQVLMWMAVAGVAGLLAAYPAAFHAVQWLG
AVYLGWMGYKMLTAKPGDAPVLNIAPRHYFRQGAVITLLNPKAIVFYMAFFPLFVNPATHRGLVTFAAMAATIATLTFLY
SLVVVLLTHFLAERMRANPTVARVLEKTAGVFLIGFGVKLAISK
>Mature_204_residues
MFGIADYGAFVAAIVLFLAIPGPGNLALITSTGKGGVRAGMAACMGVIAADQVLMWMAVAGVAGLLAAYPAAFHAVQWLG
AVYLGWMGYKMLTAKPGDAPVLNIAPRHYFRQGAVITLLNPKAIVFYMAFFPLFVNPATHRGLVTFAAMAATIATLTFLY
SLVVVLLTHFLAERMRANPTVARVLEKTAGVFLIGFGVKLAISK

Specific function: Exporter of leucine [H]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI1788099, Length=205, Percent_Identity=31.7073170731707, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI48994979, Length=205, Percent_Identity=26.3414634146341, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 21551; Mature: 21551

Theoretical pI: Translated: 10.44; Mature: 10.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFGIADYGAFVAAIVLFLAIPGPGNLALITSTGKGGVRAGMAACMGVIAADQVLMWMAVA
CCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
GVAGLLAAYPAAFHAVQWLGAVYLGWMGYKMLTAKPGDAPVLNIAPRHYFRQGAVITLLN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCEEECCHHHHHHCCCEEEEEC
PKAIVFYMAFFPLFVNPATHRGLVTFAAMAATIATLTFLYSLVVVLLTHFLAERMRANPT
CHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
VARVLEKTAGVFLIGFGVKLAISK
HHHHHHHHCCEEEEECCEEEEECC
>Mature Secondary Structure
MFGIADYGAFVAAIVLFLAIPGPGNLALITSTGKGGVRAGMAACMGVIAADQVLMWMAVA
CCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
GVAGLLAAYPAAFHAVQWLGAVYLGWMGYKMLTAKPGDAPVLNIAPRHYFRQGAVITLLN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCEEECCHHHHHHCCCEEEEEC
PKAIVFYMAFFPLFVNPATHRGLVTFAAMAATIATLTFLYSLVVVLLTHFLAERMRANPT
CHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
VARVLEKTAGVFLIGFGVKLAISK
HHHHHHHHCCEEEEECCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]