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The map label for this gene is Dml [H]

Identifier: 222102810

GI number: 222102810

Start: 475985

End: 476917

Strand: Direct

Name: Dml [H]

Synonym: Avi_7530

Alternate gene names: 222102810

Gene position: 475985-476917 (Clockwise)

Preceding gene: 222102809

Following gene: 222102811

Centisome position: 75.34

GC content: 57.45

Gene sequence:

>933_bases
ATGTTTGATAAACGGCCCAGAACCACATTTCGCGAGCTCTTCTCCAAAGAGCAGGTTTTCACCCCCTGCGTTTGGGATTG
CTATTCGGCCAAGGCGGCAGAAATGGCGGGGTTCAAGGCCATTCTCCTCAGTGGTGCATCGCTGGGTTTCAGCATGTCCG
GCGTGCCGGATATGGGGCTGCACAATCAGGAAGAACTGATCTGGGCCACTGACCGCATTGCCGACTATTCACCTCTGCCG
CTGATCATTGATGCCGATGATTGCTTTGGCGATGTTGCCCAAGCCTACCGGACATGTCGCAGGCTAGCAAAGGCCGGAGC
GGCCGCCATTCTGCTGGAAGATACACCCAATGAGCGCGGCTATGCCCGCTTTGGCCGCGCCATGGAGGCCGCGACGCTGG
CAGGCAAGGTGGATGGCAATGTCGATCACCCCGTGGTGTCGCAAGAATTGTGGCTGGCCAAGATCAAGGCAGCCCTCGAC
GCCTGCGCAGGCACGGATTGTGTGGTGATTGCCCGCACCGAATCCAAGCTGGAAAAGGGTCTGGATGATGCGATTGAGCG
CTGCGTGCGGGCCGAAGAACTGGGCGCTGAAATGACCTATGTCCATGGTCTGCGCACGCTGGAAGAATGCCAGAAAGTGG
CCAAAGCTCTGCCCGGCTGGAAGATGTTCGGCGATGTGGCAACTGTCGGCGGCAAGGCCTTCGTTGAGTTGGAAGATATC
GCCGCCCTCGGCTTCAACATGGTCACCATGCATTATCTCGAGAAAGGCTCGATGTACGGCATGATGGATTTTGGCCGTCG
TGTTTTTGCTGATCGCAGCACCCGCTATTCCGACGAGCACACCATGGGCGGCTATTCCAGAGAAGAGCAGCGCCAGATGC
TGGAGCGCGACATCGGCTGGATGGATGCGGAAGAAGAATGGAAAAAAATCTGA

Upstream 100 bases:

>100_bases
GCAAGGACGCCTGCGCGTCAAAAACCGCGAAGTAAGAAAATCCAATAGATCGGCGAACCGCAGGTTCGGTTCGCCAACGT
TCTCCTCAAGGTGTTGATCC

Downstream 100 bases:

>100_bases
AAGTCTGTCCCATAATTGTCGCTGGCGGGCTGCAAATGGCAATTTCTGCGCTTCCGGTGCTCACGTACTTGAGTACGCTC
CGCTCCGGTTCTCGAAATCA

Product: carboxyphosphonoenolpyruvate phosphonomutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MFDKRPRTTFRELFSKEQVFTPCVWDCYSAKAAEMAGFKAILLSGASLGFSMSGVPDMGLHNQEELIWATDRIADYSPLP
LIIDADDCFGDVAQAYRTCRRLAKAGAAAILLEDTPNERGYARFGRAMEAATLAGKVDGNVDHPVVSQELWLAKIKAALD
ACAGTDCVVIARTESKLEKGLDDAIERCVRAEELGAEMTYVHGLRTLEECQKVAKALPGWKMFGDVATVGGKAFVELEDI
AALGFNMVTMHYLEKGSMYGMMDFGRRVFADRSTRYSDEHTMGGYSREEQRQMLERDIGWMDAEEEWKKI

Sequences:

>Translated_310_residues
MFDKRPRTTFRELFSKEQVFTPCVWDCYSAKAAEMAGFKAILLSGASLGFSMSGVPDMGLHNQEELIWATDRIADYSPLP
LIIDADDCFGDVAQAYRTCRRLAKAGAAAILLEDTPNERGYARFGRAMEAATLAGKVDGNVDHPVVSQELWLAKIKAALD
ACAGTDCVVIARTESKLEKGLDDAIERCVRAEELGAEMTYVHGLRTLEECQKVAKALPGWKMFGDVATVGGKAFVELEDI
AALGFNMVTMHYLEKGSMYGMMDFGRRVFADRSTRYSDEHTMGGYSREEQRQMLERDIGWMDAEEEWKKI
>Mature_310_residues
MFDKRPRTTFRELFSKEQVFTPCVWDCYSAKAAEMAGFKAILLSGASLGFSMSGVPDMGLHNQEELIWATDRIADYSPLP
LIIDADDCFGDVAQAYRTCRRLAKAGAAAILLEDTPNERGYARFGRAMEAATLAGKVDGNVDHPVVSQELWLAKIKAALD
ACAGTDCVVIARTESKLEKGLDDAIERCVRAEELGAEMTYVHGLRTLEECQKVAKALPGWKMFGDVATVGGKAFVELEDI
AALGFNMVTMHYLEKGSMYGMMDFGRRVFADRSTRYSDEHTMGGYSREEQRQMLERDIGWMDAEEEWKKI

Specific function: Catalyzes the formation of proponate and pyruvate from (2R,3S)-2,3-dimethylmalate. Has no activity toward dimethylmaleate, malate, citramalate, isocitrate and citrate [H]

COG id: COG2513

COG function: function code G; PEP phosphonomutase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the isocitrate lyase/PEP mutase superfamily [H]

Homologues:

Organism=Escherichia coli, GI1786525, Length=214, Percent_Identity=33.1775700934579, Blast_Score=98, Evalue=6e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000918
- InterPro:   IPR018523
- InterPro:   IPR015813 [H]

Pfam domain/function: PF00463 ICL [H]

EC number: =4.1.3.32 [H]

Molecular weight: Translated: 34523; Mature: 34523

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
7.4 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
7.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDKRPRTTFRELFSKEQVFTPCVWDCYSAKAAEMAGFKAILLSGASLGFSMSGVPDMGL
CCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
HNQEELIWATDRIADYSPLPLIIDADDCFGDVAQAYRTCRRLAKAGAAAILLEDTPNERG
CCCCCEEEEHHHCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCH
YARFGRAMEAATLAGKVDGNVDHPVVSQELWLAKIKAALDACAGTDCVVIARTESKLEKG
HHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHC
LDDAIERCVRAEELGAEMTYVHGLRTLEECQKVAKALPGWKMFGDVATVGGKAFVELEDI
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEEHHHH
AALGFNMVTMHYLEKGSMYGMMDFGRRVFADRSTRYSDEHTMGGYSREEQRQMLERDIGW
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCC
MDAEEEWKKI
CCCHHHHHCC
>Mature Secondary Structure
MFDKRPRTTFRELFSKEQVFTPCVWDCYSAKAAEMAGFKAILLSGASLGFSMSGVPDMGL
CCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
HNQEELIWATDRIADYSPLPLIIDADDCFGDVAQAYRTCRRLAKAGAAAILLEDTPNERG
CCCCCEEEEHHHCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCH
YARFGRAMEAATLAGKVDGNVDHPVVSQELWLAKIKAALDACAGTDCVVIARTESKLEKG
HHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHC
LDDAIERCVRAEELGAEMTYVHGLRTLEECQKVAKALPGWKMFGDVATVGGKAFVELEDI
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEEHHHH
AALGFNMVTMHYLEKGSMYGMMDFGRRVFADRSTRYSDEHTMGGYSREEQRQMLERDIGW
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCC
MDAEEEWKKI
CCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA