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The map label for this gene is dppA [H]

Identifier: 222102809

GI number: 222102809

Start: 474294

End: 475919

Strand: Direct

Name: dppA [H]

Synonym: Avi_7529

Alternate gene names: 222102809

Gene position: 474294-475919 (Clockwise)

Preceding gene: 222102808

Following gene: 222102810

Centisome position: 75.07

GC content: 53.94

Gene sequence:

>1626_bases
ATGGCTAATATATTGAAAAATTGCGAAAATATCGCATCCAGATCTGTGCGCGCTATTACCGTTACACTCGCTTTGCTTGG
GGCAAGTGCAGCAATTTACGGCACCAGCATCCAATCCGCCGTCGCTGAAGAGCAACCCGTCAAGGGTGGCGAAATGACCA
TTATCAATGGTTCGGACATCAAAAGCTGGGACCCGGCCATTATTGGCGGCACCTATCCGGGTGGCCCCATGGATATGCTG
GACGCCATCTATGGCTTTCTGGTCTATGTGGACGTGGATGGCAAGGTGCAGGGTGGCATGGCCAAGAGCCTGACCAGCGC
GGATGCCAAGGTGTGGACACTGACATTGCGCGACGGTGTGAAGTTTACCGATGGTGGCTCTTACGATGCCGAGGCGGTAA
AATTCAACTGGGAGCGTCAGGCCATGCCCGACACTCTTTCACCTTCGCAAGGCTTTGTCGCCTCGTGGATTGGTGGTGTG
AAGATTGTTGATCCTTTGACACTTGAGATCACACTGCCGAAGCCGGATCGCAATTTTGGCTCATCGCTGGCACAGCTCGC
CCCCTTCATTGCCTCGCCGCAAGCGCTGAAAGCCGCCAAGACCAAAACCGATATCAAACCGGTTGGGGCCGGTGCCTTTG
TGCTGGATAGCTGGAACCAGGGCGTTTCGATGAGCATGAAGCGCAACCCGCAATACTGGGATCAACCGCGCCCCTATCTC
GACACGTTGAAATTTGCCATCATCCCCGAGACCAACAGCCGCATCGCCACCGTGGTTCAGGGTGGAGCAACGATGATGGC
GGGTTATCCCTATCAGTTCGGATCAAACGCCAAGGCCGCAGGCGTTACCACTCATGAAATTCCAATCCCCGGTCTCTATC
GCGCATACTTTAACCAGAAGAGTGGTGCCTTCACCGACCAGCGGGCGCGTGAAGCTTTCTACGAGGCGATCAATCCGTCT
AAGTTGATGCAGGCCTATACACAGGTCAGCGGTTACGACATTCCGACCAATTATTTCACGAAGTCGTCGCCCTTTTATGA
TCCGACCTATAAACTCCCAACCTACAATCCCAAACACGCTCAGGAATTGTTCGACCAGCTCGCCAAGGATGGCAAGCCAT
TCAACATCAAGCTTGTGACCTATTCCAACTCGGATTTGAAACGTCTGGCCTCCTACCTGCAACAGGCTTTGAGTGCCTAT
GATAACGTTACGGTCAATCTTCAGCTGGTTGATCAGGCCATGCTCAGCCCGACCTGTAAGGGGCAGATGAATTTCGATTT
CTGCGTCGATGGCGGCGTGCTGGTGGCCAATGGTGCAGAGCCGATCATTTCCAATCTTCTCAACTCAAACGGCAACGACA
ATTGGGGCAAATACAATAGCATCGATATGGATAAAGAGCTGGCAGAAGCCAACGCCACCATGGACGCGGCTGCGGTAAAG
GCGGCCTATGCCAAGGTGCAAAAGCGCGTTGCCACAGACCTTCCGCTTTACATTTTCGGTGCCGAGACTCGCTTCCTGCT
GCTGCGCGATACCACAGGCGGCATCGTGCCCTCCAACGGCGGCATTTTGCAGAAACAATACCTCTACGTCTGCAAGGACG
CCTGCGCGTCAAAAACCGCGAAGTAA

Upstream 100 bases:

>100_bases
AACATTGGCCCCAACGCTTTTGGGGCAGATGTTTTTCGCCGTTCAAAAAACAAGGGGAACTGCGGTGGTTCGTATGAACT
GCCGTAAAACGGAGAAAACC

Downstream 100 bases:

>100_bases
GAAAATCCAATAGATCGGCGAACCGCAGGTTCGGTTCGCCAACGTTCTCCTCAAGGTGTTGATCCATGTTTGATAAACGG
CCCAGAACCACATTTCGCGA

Product: ABC transporter substrate binding protein (dipeptide)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 541; Mature: 540

Protein sequence:

>541_residues
MANILKNCENIASRSVRAITVTLALLGASAAIYGTSIQSAVAEEQPVKGGEMTIINGSDIKSWDPAIIGGTYPGGPMDML
DAIYGFLVYVDVDGKVQGGMAKSLTSADAKVWTLTLRDGVKFTDGGSYDAEAVKFNWERQAMPDTLSPSQGFVASWIGGV
KIVDPLTLEITLPKPDRNFGSSLAQLAPFIASPQALKAAKTKTDIKPVGAGAFVLDSWNQGVSMSMKRNPQYWDQPRPYL
DTLKFAIIPETNSRIATVVQGGATMMAGYPYQFGSNAKAAGVTTHEIPIPGLYRAYFNQKSGAFTDQRAREAFYEAINPS
KLMQAYTQVSGYDIPTNYFTKSSPFYDPTYKLPTYNPKHAQELFDQLAKDGKPFNIKLVTYSNSDLKRLASYLQQALSAY
DNVTVNLQLVDQAMLSPTCKGQMNFDFCVDGGVLVANGAEPIISNLLNSNGNDNWGKYNSIDMDKELAEANATMDAAAVK
AAYAKVQKRVATDLPLYIFGAETRFLLLRDTTGGIVPSNGGILQKQYLYVCKDACASKTAK

Sequences:

>Translated_541_residues
MANILKNCENIASRSVRAITVTLALLGASAAIYGTSIQSAVAEEQPVKGGEMTIINGSDIKSWDPAIIGGTYPGGPMDML
DAIYGFLVYVDVDGKVQGGMAKSLTSADAKVWTLTLRDGVKFTDGGSYDAEAVKFNWERQAMPDTLSPSQGFVASWIGGV
KIVDPLTLEITLPKPDRNFGSSLAQLAPFIASPQALKAAKTKTDIKPVGAGAFVLDSWNQGVSMSMKRNPQYWDQPRPYL
DTLKFAIIPETNSRIATVVQGGATMMAGYPYQFGSNAKAAGVTTHEIPIPGLYRAYFNQKSGAFTDQRAREAFYEAINPS
KLMQAYTQVSGYDIPTNYFTKSSPFYDPTYKLPTYNPKHAQELFDQLAKDGKPFNIKLVTYSNSDLKRLASYLQQALSAY
DNVTVNLQLVDQAMLSPTCKGQMNFDFCVDGGVLVANGAEPIISNLLNSNGNDNWGKYNSIDMDKELAEANATMDAAAVK
AAYAKVQKRVATDLPLYIFGAETRFLLLRDTTGGIVPSNGGILQKQYLYVCKDACASKTAK
>Mature_540_residues
ANILKNCENIASRSVRAITVTLALLGASAAIYGTSIQSAVAEEQPVKGGEMTIINGSDIKSWDPAIIGGTYPGGPMDMLD
AIYGFLVYVDVDGKVQGGMAKSLTSADAKVWTLTLRDGVKFTDGGSYDAEAVKFNWERQAMPDTLSPSQGFVASWIGGVK
IVDPLTLEITLPKPDRNFGSSLAQLAPFIASPQALKAAKTKTDIKPVGAGAFVLDSWNQGVSMSMKRNPQYWDQPRPYLD
TLKFAIIPETNSRIATVVQGGATMMAGYPYQFGSNAKAAGVTTHEIPIPGLYRAYFNQKSGAFTDQRAREAFYEAINPSK
LMQAYTQVSGYDIPTNYFTKSSPFYDPTYKLPTYNPKHAQELFDQLAKDGKPFNIKLVTYSNSDLKRLASYLQQALSAYD
NVTVNLQLVDQAMLSPTCKGQMNFDFCVDGGVLVANGAEPIISNLLNSNGNDNWGKYNSIDMDKELAEANATMDAAAVKA
AYAKVQKRVATDLPLYIFGAETRFLLLRDTTGGIVPSNGGILQKQYLYVCKDACASKTAK

Specific function: Part of the ABC transporter complex gsiABCD involved in glutathione import [H]

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1787052, Length=354, Percent_Identity=27.9661016949153, Blast_Score=112, Evalue=7e-26,
Organism=Escherichia coli, GI1787495, Length=526, Percent_Identity=26.425855513308, Blast_Score=109, Evalue=5e-25,
Organism=Escherichia coli, GI87081878, Length=452, Percent_Identity=25.4424778761062, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1789887, Length=437, Percent_Identity=25.629290617849, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1789397, Length=480, Percent_Identity=25, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1787762, Length=534, Percent_Identity=25.0936329588015, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789966, Length=329, Percent_Identity=25.531914893617, Blast_Score=75, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 58636; Mature: 58505

Theoretical pI: Translated: 7.79; Mature: 7.79

Prosite motif: PS01040 SBP_BACTERIAL_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANILKNCENIASRSVRAITVTLALLGASAAIYGTSIQSAVAEEQPVKGGEMTIINGSDI
CCHHHHHHHHHHHCCHHHHHHHHHHHHCCHHEECCHHHHHHHHCCCCCCCCEEEEECCCC
KSWDPAIIGGTYPGGPMDMLDAIYGFLVYVDVDGKVQGGMAKSLTSADAKVWTLTLRDGV
CCCCCEEECCCCCCCHHHHHHHHHHEEEEEEECCCCCCCHHHHHCCCCCEEEEEEECCCE
KFTDGGSYDAEAVKFNWERQAMPDTLSPSQGFVASWIGGVKIVDPLTLEITLPKPDRNFG
EECCCCCCCCCEEEECCHHHCCCCCCCCCCCHHHHHHCCEEEECCEEEEEEECCCCCHHH
SSLAQLAPFIASPQALKAAKTKTDIKPVGAGAFVLDSWNQGVSMSMKRNPQYWDQPRPYL
HHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCEEEEECCCCCCEEEECCCCCCCCCCCCHH
DTLKFAIIPETNSRIATVVQGGATMMAGYPYQFGSNAKAAGVTTHEIPIPGLYRAYFNQK
HCEEEEEEECCCCCEEEEEECCCEEEECCCEECCCCCCCCCCEECCCCCCHHHHHHHCCC
SGAFTDQRAREAFYEAINPSKLMQAYTQVSGYDIPTNYFTKSSPFYDPTYKLPTYNPKHA
CCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHH
QELFDQLAKDGKPFNIKLVTYSNSDLKRLASYLQQALSAYDNVTVNLQLVDQAMLSPTCK
HHHHHHHHHCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHCCEEEEEEEECHHHCCCCCC
GQMNFDFCVDGGVLVANGAEPIISNLLNSNGNDNWGKYNSIDMDKELAEANATMDAAAVK
CCCCEEEEECCCEEEECCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHH
AAYAKVQKRVATDLPLYIFGAETRFLLLRDTTGGIVPSNGGILQKQYLYVCKDACASKTA
HHHHHHHHHHHCCCCEEEEECCEEEEEEEECCCCEECCCCCEEHHHHHHHHHHHHHCCCC
K
C
>Mature Secondary Structure 
ANILKNCENIASRSVRAITVTLALLGASAAIYGTSIQSAVAEEQPVKGGEMTIINGSDI
CHHHHHHHHHHHCCHHHHHHHHHHHHCCHHEECCHHHHHHHHCCCCCCCCEEEEECCCC
KSWDPAIIGGTYPGGPMDMLDAIYGFLVYVDVDGKVQGGMAKSLTSADAKVWTLTLRDGV
CCCCCEEECCCCCCCHHHHHHHHHHEEEEEEECCCCCCCHHHHHCCCCCEEEEEEECCCE
KFTDGGSYDAEAVKFNWERQAMPDTLSPSQGFVASWIGGVKIVDPLTLEITLPKPDRNFG
EECCCCCCCCCEEEECCHHHCCCCCCCCCCCHHHHHHCCEEEECCEEEEEEECCCCCHHH
SSLAQLAPFIASPQALKAAKTKTDIKPVGAGAFVLDSWNQGVSMSMKRNPQYWDQPRPYL
HHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCEEEEECCCCCCEEEECCCCCCCCCCCCHH
DTLKFAIIPETNSRIATVVQGGATMMAGYPYQFGSNAKAAGVTTHEIPIPGLYRAYFNQK
HCEEEEEEECCCCCEEEEEECCCEEEECCCEECCCCCCCCCCEECCCCCCHHHHHHHCCC
SGAFTDQRAREAFYEAINPSKLMQAYTQVSGYDIPTNYFTKSSPFYDPTYKLPTYNPKHA
CCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHH
QELFDQLAKDGKPFNIKLVTYSNSDLKRLASYLQQALSAYDNVTVNLQLVDQAMLSPTCK
HHHHHHHHHCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHCCEEEEEEEECHHHCCCCCC
GQMNFDFCVDGGVLVANGAEPIISNLLNSNGNDNWGKYNSIDMDKELAEANATMDAAAVK
CCCCEEEEECCCEEEECCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHH
AAYAKVQKRVATDLPLYIFGAETRFLLLRDTTGGIVPSNGGILQKQYLYVCKDACASKTA
HHHHHHHHHHHCCCCEEEEECCEEEEEEEECCCCEECCCCCEEHHHHHHHHHHHHHCCCC
K
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA