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The map label for this gene is gsiC [H]

Identifier: 222102619

GI number: 222102619

Start: 226099

End: 227079

Strand: Reverse

Name: gsiC [H]

Synonym: Avi_7271

Alternate gene names: 222102619

Gene position: 227079-226099 (Counterclockwise)

Preceding gene: 222102620

Following gene: 222102618

Centisome position: 35.94

GC content: 56.57

Gene sequence:

>981_bases
ATGTTCGCATTGAATTTCCTCGTCAGACGGCTGTTTCAGGGTGCGATTATTATTTTTCTGGTGTCTTTGCTGATCTTCAC
CCTGCTGCGGGTGGTGCCGGGCGATCCCGTGCGCATGATGGCGGGTGGCATGGCTCCTGAAGCCCTGATCGAGAAAATCG
CCAAGGATATGGGATTGCGTGATCCGATTCTCGTTCAGTTCGGGCGCTATATGTCTGGCGTGGTGCAAGGTGACCTTGGC
GAATCCTTTGTGCGGCCCGCCAATGGCGCGGCAACAGGCGGCTCTAGCTTCAACGATACAACGCGGGGCGAGCGCGCCAA
GGTTTTCACCCTGATTTTTGATGCGCTGCCCATGACCTTGCAACTGGCGGCGGTTACGCTTGTGATAGCCCTGGTATTTT
CCAGCATTGTCGGTGTAGCGGGAGGATTGGCACCGGGGCGATGGCCGGACAAGCTTGCCTTCTATATCTCCTCGATTTTC
ATATCCCTGCCGAATTTCTGGCTTGGAATCGTGCTGGCCTTGCTGTTTTCGGTCAAGCTCGGCTGGCTTCCGGCCATCGG
CTATCAGGGCTTTGCCTATACCATCCTGCCCGCCATCGTCCTGGCCGTAGAGCTTGCGCCGGTGTTGATCCGCACGCTGG
TCAGTTCCGTCTCTGCCCAGATGATGGAGCCTTACGTGTCTGTCGGACGGGTTCGTGGCCTGAGCAATACCCGTATCATT
GCCAATCATGCGCTGCGCAATGCGTCCGTGCCGTTGCTCAATCTGCTGGGCGTGCAATTTTCCAGTCTGCTCGGCGGCGT
GATCATCGTTGAATATATCTTCGATTACCCCGGCCTTGGCCTGCTGACCATCAACGCCGTGCTGCAACGGGATTTTCCGC
TGATCCAAGGCATTGCCATCGTCACCAGCGCCATCTTCGTGCTGATCAACATCCTCGTTGATCTCGTTGCCACCACCATT
GATCCGAGGCTCGAATACTGA

Upstream 100 bases:

>100_bases
TCAAAGCCTGCGGCATGATGCTGCACCGGACGTAAGACTGGCCGCACGCCGGAGATTTCAGCGTGCGGCGACCATCAGGA
CCGAAGCGGAGTGCATGTCG

Downstream 100 bases:

>100_bases
TGACCTTCACCAGCCCAGCCCCTTCGGCCATCATGGCACCGGTCCTGTCGCGATCGATCCCCCGACGGATCTATGACAAG
GCTTCTTCCACACCGGGTTT

Product: ABC transporter membrane spanning protein (oligopeptide)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MFALNFLVRRLFQGAIIIFLVSLLIFTLLRVVPGDPVRMMAGGMAPEALIEKIAKDMGLRDPILVQFGRYMSGVVQGDLG
ESFVRPANGAATGGSSFNDTTRGERAKVFTLIFDALPMTLQLAAVTLVIALVFSSIVGVAGGLAPGRWPDKLAFYISSIF
ISLPNFWLGIVLALLFSVKLGWLPAIGYQGFAYTILPAIVLAVELAPVLIRTLVSSVSAQMMEPYVSVGRVRGLSNTRII
ANHALRNASVPLLNLLGVQFSSLLGGVIIVEYIFDYPGLGLLTINAVLQRDFPLIQGIAIVTSAIFVLINILVDLVATTI
DPRLEY

Sequences:

>Translated_326_residues
MFALNFLVRRLFQGAIIIFLVSLLIFTLLRVVPGDPVRMMAGGMAPEALIEKIAKDMGLRDPILVQFGRYMSGVVQGDLG
ESFVRPANGAATGGSSFNDTTRGERAKVFTLIFDALPMTLQLAAVTLVIALVFSSIVGVAGGLAPGRWPDKLAFYISSIF
ISLPNFWLGIVLALLFSVKLGWLPAIGYQGFAYTILPAIVLAVELAPVLIRTLVSSVSAQMMEPYVSVGRVRGLSNTRII
ANHALRNASVPLLNLLGVQFSSLLGGVIIVEYIFDYPGLGLLTINAVLQRDFPLIQGIAIVTSAIFVLINILVDLVATTI
DPRLEY
>Mature_326_residues
MFALNFLVRRLFQGAIIIFLVSLLIFTLLRVVPGDPVRMMAGGMAPEALIEKIAKDMGLRDPILVQFGRYMSGVVQGDLG
ESFVRPANGAATGGSSFNDTTRGERAKVFTLIFDALPMTLQLAAVTLVIALVFSSIVGVAGGLAPGRWPDKLAFYISSIF
ISLPNFWLGIVLALLFSVKLGWLPAIGYQGFAYTILPAIVLAVELAPVLIRTLVSSVSAQMMEPYVSVGRVRGLSNTRII
ANHALRNASVPLLNLLGVQFSSLLGGVIIVEYIFDYPGLGLLTINAVLQRDFPLIQGIAIVTSAIFVLINILVDLVATTI
DPRLEY

Specific function: Part of the ABC transporter complex gsiABCD involved in glutathione import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787053, Length=323, Percent_Identity=36.5325077399381, Blast_Score=215, Evalue=2e-57,
Organism=Escherichia coli, GI1789888, Length=326, Percent_Identity=31.9018404907975, Blast_Score=175, Evalue=4e-45,
Organism=Escherichia coli, GI1789965, Length=358, Percent_Identity=31.8435754189944, Blast_Score=158, Evalue=4e-40,
Organism=Escherichia coli, GI1787497, Length=325, Percent_Identity=26.4615384615385, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI1787761, Length=349, Percent_Identity=30.3724928366762, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1787550, Length=261, Percent_Identity=30.6513409961686, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1788504, Length=304, Percent_Identity=24.6710526315789, Blast_Score=79, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 35122; Mature: 35122

Theoretical pI: Translated: 9.56; Mature: 9.56

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFALNFLVRRLFQGAIIIFLVSLLIFTLLRVVPGDPVRMMAGGMAPEALIEKIAKDMGLR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCHHHHHHHHHHHCCCC
DPILVQFGRYMSGVVQGDLGESFVRPANGAATGGSSFNDTTRGERAKVFTLIFDALPMTL
CHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
QLAAVTLVIALVFSSIVGVAGGLAPGRWPDKLAFYISSIFISLPNFWLGIVLALLFSVKL
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GWLPAIGYQGFAYTILPAIVLAVELAPVLIRTLVSSVSAQMMEPYVSVGRVRGLSNTRII
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
ANHALRNASVPLLNLLGVQFSSLLGGVIIVEYIFDYPGLGLLTINAVLQRDFPLIQGIAI
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHH
VTSAIFVLINILVDLVATTIDPRLEY
HHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MFALNFLVRRLFQGAIIIFLVSLLIFTLLRVVPGDPVRMMAGGMAPEALIEKIAKDMGLR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCHHHHHHHHHHHCCCC
DPILVQFGRYMSGVVQGDLGESFVRPANGAATGGSSFNDTTRGERAKVFTLIFDALPMTL
CHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
QLAAVTLVIALVFSSIVGVAGGLAPGRWPDKLAFYISSIFISLPNFWLGIVLALLFSVKL
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GWLPAIGYQGFAYTILPAIVLAVELAPVLIRTLVSSVSAQMMEPYVSVGRVRGLSNTRII
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
ANHALRNASVPLLNLLGVQFSSLLGGVIIVEYIFDYPGLGLLTINAVLQRDFPLIQGIAI
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHH
VTSAIFVLINILVDLVATTIDPRLEY
HHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]