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The map label for this gene is dppA [H]

Identifier: 222102620

GI number: 222102620

Start: 227162

End: 228748

Strand: Reverse

Name: dppA [H]

Synonym: Avi_7272

Alternate gene names: 222102620

Gene position: 228748-227162 (Counterclockwise)

Preceding gene: 222102623

Following gene: 222102619

Centisome position: 36.21

GC content: 55.89

Gene sequence:

>1587_bases
ATGAGTTCAGAGATCAATCGCCGTCGCTTCCTGCAAGGAACCGTCGGGGCGGCCGCTGCCGCAGGCTTTATGCAGATGAA
CCCCGACTTCTTCATTTCCTCAGCCTTTGCCCAGTCGGGCAAGACCATGACGTTTCTCTCTGCCGAAAACATCACCGGCA
ACTGGGACCCGACGGCCCACACGACGCTCTCGCAGAAAAATATCGAGGGTTTCGTCATGGGCTTCCTGACGCGCTCACCG
ATGAAGCTCGATAATCCCGGCGAGGTGGTCTACGAGCTGGCAACCGACATCAAGCTGCTGGATGCACATCGGTTGCAGAT
AACGCTGCGGCAGGGCATCACTTTTCATGATGGCAAGCCGTTCAAGGCCGAAGATGTCAAGGCAACTTTGGAATATGGCT
CGAGGGCCGATCGTCCGGCCCAATGGTATCCAGGACCGACCGAAACCCTGACCATCGAAACACCGGACGACTACACCGTC
ATTATCGACACCTCCAAGGGTGGTTATCCGGCCCATCTCTTCATCTTCCTCGCCTCTTTCCTTCCAATGATGTCGGCAAA
GGACGTGGCAGGTGGCCCGGGTGGGGTTCTCTCTCAACGCTTGAATGGCACGGGACCGTTCAAATTCGTTGAGCAGCGCG
GCAATGACACGGTGATGGTCGCTTTCGATGGCTATTTCAAAGGCAAGCCAGGCATTCCCGGCATCAACTTTACTTTCACT
GGCGATTCCACCACGCGCATGCTGTCGCTGATGAATGGTCAGGCTTCGATTGTCGAGCGTCTGGAGCCGGAACAGGTGGC
AACCTTGAAAGGCAATCCGCAAATCGCCATCAACGAGGTGGTTTCGGTTGAAAACAAATATCTTTGGTTCCGGTGCTCCA
AGCCACCTTTCAACGATCCGCGCGTCCGGCTGGCAGCTTGCCACGCCATCGACCGTGACATGATCCTCGAAGTGCTCGGA
TCGGCAGGCCATGCATCTTCCAACTTCGTGTCACCGGTCAAGTTCGGCTATGCCGATCTGGAGAATTATCCGAAATACGA
TCCAGAAAAGTGCCAGGCACTGCTGGCGGAAGCTGGCTTTCCAAACGGTAAGGGCTTGCCGCCCTTGGAATATATTACCT
CGGTTGGGTTCTATCCCAAGACCAAGGAATATGGCGAGGTGCTAACGGGCATGCTGAACGAACAGGGCTTCCCCGTCAGC
CTGACCGTGCTGGAGCCTGCGGCATGGAACGAGCAATTGTACGATCGCCCAGGCGGCGGACCCGGCCATATGGTCGATTG
CGGCTGGTCAACCGCATCACCGGAGCCCGATCTTGTTCTGCGAACGCACTTCCATTCAAGCTCCAAGCGCATTTGCGGCA
TTGTCGACAAGGACATTGATGCAAGCCTCGACAAGGAGCGCAATGCGGCAAACCTGGAAGAGCGCAAAAAAGTTCTGCAA
TCCGAAACGATGCCTTTGATCGCTTCGAAAATGCCGGCCCTGTCGCTGTTCACCTCTGTCATGATCCACGCCATGCAAAA
GGAGTTCAAGGAAGGCCTCTACATCTATCCTGACGGGTCCATGGACGCTTCAAAGCCTGCGGCATGA

Upstream 100 bases:

>100_bases
AGGCGCTGAATCAAAGTTTCAGCAGGATGGCATGCGAATTGCTTTGACTGATTTGACCGTTTTGTCGGTTCTGTGAATTT
CTATAAGAAAAGGGGAACCT

Downstream 100 bases:

>100_bases
TGCTGCACCGGACGTAAGACTGGCCGCACGCCGGAGATTTCAGCGTGCGGCGACCATCAGGACCGAAGCGGAGTGCATGT
CGATGTTCGCATTGAATTTC

Product: ABC-type dipeptide transport system, periplasmic component

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Dipeptide-binding protein; DBP [H]

Number of amino acids: Translated: 528; Mature: 527

Protein sequence:

>528_residues
MSSEINRRRFLQGTVGAAAAAGFMQMNPDFFISSAFAQSGKTMTFLSAENITGNWDPTAHTTLSQKNIEGFVMGFLTRSP
MKLDNPGEVVYELATDIKLLDAHRLQITLRQGITFHDGKPFKAEDVKATLEYGSRADRPAQWYPGPTETLTIETPDDYTV
IIDTSKGGYPAHLFIFLASFLPMMSAKDVAGGPGGVLSQRLNGTGPFKFVEQRGNDTVMVAFDGYFKGKPGIPGINFTFT
GDSTTRMLSLMNGQASIVERLEPEQVATLKGNPQIAINEVVSVENKYLWFRCSKPPFNDPRVRLAACHAIDRDMILEVLG
SAGHASSNFVSPVKFGYADLENYPKYDPEKCQALLAEAGFPNGKGLPPLEYITSVGFYPKTKEYGEVLTGMLNEQGFPVS
LTVLEPAAWNEQLYDRPGGGPGHMVDCGWSTASPEPDLVLRTHFHSSSKRICGIVDKDIDASLDKERNAANLEERKKVLQ
SETMPLIASKMPALSLFTSVMIHAMQKEFKEGLYIYPDGSMDASKPAA

Sequences:

>Translated_528_residues
MSSEINRRRFLQGTVGAAAAAGFMQMNPDFFISSAFAQSGKTMTFLSAENITGNWDPTAHTTLSQKNIEGFVMGFLTRSP
MKLDNPGEVVYELATDIKLLDAHRLQITLRQGITFHDGKPFKAEDVKATLEYGSRADRPAQWYPGPTETLTIETPDDYTV
IIDTSKGGYPAHLFIFLASFLPMMSAKDVAGGPGGVLSQRLNGTGPFKFVEQRGNDTVMVAFDGYFKGKPGIPGINFTFT
GDSTTRMLSLMNGQASIVERLEPEQVATLKGNPQIAINEVVSVENKYLWFRCSKPPFNDPRVRLAACHAIDRDMILEVLG
SAGHASSNFVSPVKFGYADLENYPKYDPEKCQALLAEAGFPNGKGLPPLEYITSVGFYPKTKEYGEVLTGMLNEQGFPVS
LTVLEPAAWNEQLYDRPGGGPGHMVDCGWSTASPEPDLVLRTHFHSSSKRICGIVDKDIDASLDKERNAANLEERKKVLQ
SETMPLIASKMPALSLFTSVMIHAMQKEFKEGLYIYPDGSMDASKPAA
>Mature_527_residues
SSEINRRRFLQGTVGAAAAAGFMQMNPDFFISSAFAQSGKTMTFLSAENITGNWDPTAHTTLSQKNIEGFVMGFLTRSPM
KLDNPGEVVYELATDIKLLDAHRLQITLRQGITFHDGKPFKAEDVKATLEYGSRADRPAQWYPGPTETLTIETPDDYTVI
IDTSKGGYPAHLFIFLASFLPMMSAKDVAGGPGGVLSQRLNGTGPFKFVEQRGNDTVMVAFDGYFKGKPGIPGINFTFTG
DSTTRMLSLMNGQASIVERLEPEQVATLKGNPQIAINEVVSVENKYLWFRCSKPPFNDPRVRLAACHAIDRDMILEVLGS
AGHASSNFVSPVKFGYADLENYPKYDPEKCQALLAEAGFPNGKGLPPLEYITSVGFYPKTKEYGEVLTGMLNEQGFPVSL
TVLEPAAWNEQLYDRPGGGPGHMVDCGWSTASPEPDLVLRTHFHSSSKRICGIVDKDIDASLDKERNAANLEERKKVLQS
ETMPLIASKMPALSLFTSVMIHAMQKEFKEGLYIYPDGSMDASKPAA

Specific function: Dipeptide-binding protein of a transport system that can be subject to osmotic shock. DppA is also required for peptide chemotaxis [H]

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=462, Percent_Identity=26.4069264069264, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1787052, Length=472, Percent_Identity=26.4830508474576, Blast_Score=109, Evalue=5e-25,
Organism=Escherichia coli, GI1787762, Length=442, Percent_Identity=25.1131221719457, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1787551, Length=326, Percent_Identity=23.9263803680982, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1789887, Length=389, Percent_Identity=24.9357326478149, Blast_Score=70, Evalue=4e-13,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 57876; Mature: 57745

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSEINRRRFLQGTVGAAAAAGFMQMNPDFFISSAFAQSGKTMTFLSAENITGNWDPTAH
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHCCCCEEEEEEECCCCCCCCCCCC
TTLSQKNIEGFVMGFLTRSPMKLDNPGEVVYELATDIKLLDAHRLQITLRQGITFHDGKP
CEECCCCCCCCEEHHHCCCCCCCCCCHHHHHHHHHCEEEECCEEEEEEEECCCEECCCCC
FKAEDVKATLEYGSRADRPAQWYPGPTETLTIETPDDYTVIIDTSKGGYPAHLFIFLASF
CCHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCEEEEEECCCCCCHHHHHHHHHHH
LPMMSAKDVAGGPGGVLSQRLNGTGPFKFVEQRGNDTVMVAFDGYFKGKPGIPGINFTFT
HHHHCCCCCCCCCCHHHHHHCCCCCCCHHHHHCCCCEEEEEECCEECCCCCCCCCEEEEC
GDSTTRMLSLMNGQASIVERLEPEQVATLKGNPQIAINEVVSVENKYLWFRCSKPPFNDP
CCCHHHHHHHHCCHHHHHHHCCCCCEEEECCCCCEEEEHHHCCCCEEEEEEECCCCCCCC
RVRLAACHAIDRDMILEVLGSAGHASSNFVSPVKFGYADLENYPKYDPEKCQALLAEAGF
CEEEEHHHHCCHHHHHHHHCCCCCCCCCCCCHHHHCCHHHHCCCCCCHHHHHHHHHHCCC
PNGKGLPPLEYITSVGFYPKTKEYGEVLTGMLNEQGFPVSLTVLEPAAWNEQLYDRPGGG
CCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHCCCCCC
PGHMVDCGWSTASPEPDLVLRTHFHSSSKRICGIVDKDIDASLDKERNAANLEERKKVLQ
CCCEEECCCCCCCCCCCEEEEEECCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHH
SETMPLIASKMPALSLFTSVMIHAMQKEFKEGLYIYPDGSMDASKPAA
HCCCCHHHHCCCHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCC
>Mature Secondary Structure 
SSEINRRRFLQGTVGAAAAAGFMQMNPDFFISSAFAQSGKTMTFLSAENITGNWDPTAH
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHCCCCEEEEEEECCCCCCCCCCCC
TTLSQKNIEGFVMGFLTRSPMKLDNPGEVVYELATDIKLLDAHRLQITLRQGITFHDGKP
CEECCCCCCCCEEHHHCCCCCCCCCCHHHHHHHHHCEEEECCEEEEEEEECCCEECCCCC
FKAEDVKATLEYGSRADRPAQWYPGPTETLTIETPDDYTVIIDTSKGGYPAHLFIFLASF
CCHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCEEEEEECCCCCCHHHHHHHHHHH
LPMMSAKDVAGGPGGVLSQRLNGTGPFKFVEQRGNDTVMVAFDGYFKGKPGIPGINFTFT
HHHHCCCCCCCCCCHHHHHHCCCCCCCHHHHHCCCCEEEEEECCEECCCCCCCCCEEEEC
GDSTTRMLSLMNGQASIVERLEPEQVATLKGNPQIAINEVVSVENKYLWFRCSKPPFNDP
CCCHHHHHHHHCCHHHHHHHCCCCCEEEECCCCCEEEEHHHCCCCEEEEEEECCCCCCCC
RVRLAACHAIDRDMILEVLGSAGHASSNFVSPVKFGYADLENYPKYDPEKCQALLAEAGF
CEEEEHHHHCCHHHHHHHHCCCCCCCCCCCCHHHHCCHHHHCCCCCCHHHHHHHHHHCCC
PNGKGLPPLEYITSVGFYPKTKEYGEVLTGMLNEQGFPVSLTVLEPAAWNEQLYDRPGGG
CCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHCCCCCC
PGHMVDCGWSTASPEPDLVLRTHFHSSSKRICGIVDKDIDASLDKERNAANLEERKKVLQ
CCCEEECCCCCCCCCCCEEEEEECCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHH
SETMPLIASKMPALSLFTSVMIHAMQKEFKEGLYIYPDGSMDASKPAA
HCCCCHHHHCCCHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1702779; 1956284; 7536291; 8041620; 9278503; 9298646; 9600841; 8563629; 8527431 [H]