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The map label for this gene is ina [H]

Identifier: 222096477

GI number: 222096477

Start: 2755990

End: 2758374

Strand: Reverse

Name: ina [H]

Synonym: BCQ_2817

Alternate gene names: 222096477

Gene position: 2758374-2755990 (Counterclockwise)

Preceding gene: 222096478

Following gene: 222096476

Centisome position: 52.9

GC content: 39.75

Gene sequence:

>2385_bases
TTGAGAAAGAAAAAGAAATTAAAACCTTTAGCGGTATTAACAACAGCAGCCGTGCTAAGTAGTACATTTGCTTTTGGAAG
CCATGCAGCATATGCTGATGCGCCACCATCTCTACCAATTGATGAGCATTTAATACCAGAGGAGCGATTGGCAGAAGCAC
TGAAGCAAAGGGGAGTAATTGATGAATCTGCATCACAAGCTGAGACATCAAAGGCTGTCGAAAAATATGTTGAGAAAAAG
AAAGGGGAAAACCCTGGAAAAGAAATCTTGACAGGAGATAATCTTACGCAAGAAGCTTCAGATTTTATGAAAAAAGTAAA
AGATACAAAAATGCAGGAAAATGAACAGGCGCAGCAGCCCGAAGTAGGACCAGTAGCTGGGCAAAGTGCAGGATTGAACC
CAGGAAAATTAAATGGAAAAGTACCAACTACACCAGCGAAGCAAGCTGAGTACAATGGGGCTGTTCGAAAAGATAAAGTA
CTTGTATTACTCGTAGAATTTAGCGATTTTAAGCATAATAATATTGATCAAGAACCGGGTTATATGTATTCTAAGGACTT
TAATCGTGAACATTATCAAAAAATGTTATTTGGTGATGAGCCATTTACGTTATTTGATGGATCGAAGATTAATACATTTA
AACAGTATTATGAAGAACAATCTGGCGGAAGCTACACAGTTGATGGAACTGTAACGGAATGGCTTACTGTTCCAGGAAAA
GCGTCAGATTATGGTGCTGATGCGGGAACTGGTCATGACAATAAAGGTCCTTTAGGCCCAAAAGATTTTGTGAAAGAAGC
ATTGAAAGCAGCGGTAGCAAAAGGCATTAATTTAGCTGATTATGATCAATTTGATCAATACGACCAAGATGGTGATGGAA
ATAAAAATGAGCCAGATGGAATCATTGATCATTTAATGGTAGTACATGCAGGCGTGGGACAAGAAGCTGGCGGTGGTAAA
TTGAAAGATGATGCGATTTGGTCTCATCGCTCAAAACTAGGATCGAAGCCATATGCGATTGATGGTACAAAATCTTCTGT
TTCGAACTGGGGCGGAAAGATGGCTGCATACGATTATACAATCGAGCCTGAGGACGGAGCGGTTGGTGTATTTGCACATG
AATATGGTCATGATTTAGGCTTGCCAGATGAATATGATACAAAGTATTCAGGACAAGGTGAACCAGTTGAATCATGGTCC
CTAATGAGCGGCGGTAGCTGGGCTGGAAAAATTGCAGGTACAGAGCCAACAAGTTTCTCACCACAAAATAAAGAGTTTTT
CCAAAAAAATATGAAGGGGAACTGGGCGAATATTATTGAGGTCGATTATGATAAACTTCGCACGGGAATCGGTACTGCAA
CGTATTTAGATCAAAGTGTGACAAAATCAAAACGACCAGGAATCATTCGTGTTAACTTGCCGGACAAAGATATAAAAAAT
ATTGAGTCAGCATTTGGTAAGAAGTTTTATTACAGCACGAAAGGAAATGACATTCATACAACACTTGAGACACCAGTATT
TGACTTAACGACTGCAACGGATGCCAAGTTCGATTATAAGGCATTTTACGAACTGGAAGCGAAGTATGATTTCCTTGACG
TATATGCGATTGCAGAAGATGGAACGAAGACACTCATTGATCGAATGGGCGAAAAAGATGTAAAAGGCGGTATAGATACA
ACGGATGGTAAGTGGATTGATAAATCATATGATTTAAATCAATTCAAAGGAAAGAAAGTAAAACTGCAATTTGAGTATGT
AACAGATATTGCAGTAGCATATAAAGGATTTGCGTTAGACAATGCAGCATTAACTGTAGATGGAAAAGTTGTTTTCTCTG
ATGACGCAGAAGGCCAGCCAGCAATGACATTAAAAGGATTTACTGTGTCTAACGGATTTGAACAGAAGAAACATAACTAC
TATATCGAGTGGCGTAATTACGCTGGGTCTGATACTGCATTACAATATGCACGTGGTCCAGTATTTAATACAGGAATGGT
TGTATGGTATGCGGATCAAAGCTTTACAGATAACTGGGTAGGCGTTCATCCAGGTGAAGGGTTCCTTGGAGTAGTTGATT
CTCATCCAGAGGCAATCGTAGGAACATTAAACGGACAACCTACTGTGAAGAGCAGTACACGTTATCAAATTGCCGATGCG
GCATTCTCATTTGATCAAACGCCAGCATGGAAAGTAAATTCACCAACTCGCGGTATCTTTGACTATAAAGGATTACCAGG
AGTTGCAAAATTTGATGATTCTAAGCAATACATCAACAGCGTTATTCCAGATGCGGGACGTAAGTTACCTAAACTAGGAT
TGAAGTTTGAAGTAGTAGGTCAAGCTGAAGACAAGTCTGCAGGTGCAGTTTGGATCCATCGATAA

Upstream 100 bases:

>100_bases
CATTTTAGCGCTTTAAAAAGATTGAATATTCGTATTATAACGAATATTATATTGCTATCGGCAAAAATCGATAATTTGCA
GACACTGGGGAGGAAATACA

Downstream 100 bases:

>100_bases
AATAAAATGAAGAGGAGCTGCCATAAGCCGGTGAAACTGACTTATGGCAGCTCTTTTCTGCTTGTGAAAAAGTTTGTAGA
AGTTCATTTTATAAATAAAA

Product: proteinase vca0223

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 794; Mature: 794

Protein sequence:

>794_residues
MRKKKKLKPLAVLTTAAVLSSTFAFGSHAAYADAPPSLPIDEHLIPEERLAEALKQRGVIDESASQAETSKAVEKYVEKK
KGENPGKEILTGDNLTQEASDFMKKVKDTKMQENEQAQQPEVGPVAGQSAGLNPGKLNGKVPTTPAKQAEYNGAVRKDKV
LVLLVEFSDFKHNNIDQEPGYMYSKDFNREHYQKMLFGDEPFTLFDGSKINTFKQYYEEQSGGSYTVDGTVTEWLTVPGK
ASDYGADAGTGHDNKGPLGPKDFVKEALKAAVAKGINLADYDQFDQYDQDGDGNKNEPDGIIDHLMVVHAGVGQEAGGGK
LKDDAIWSHRSKLGSKPYAIDGTKSSVSNWGGKMAAYDYTIEPEDGAVGVFAHEYGHDLGLPDEYDTKYSGQGEPVESWS
LMSGGSWAGKIAGTEPTSFSPQNKEFFQKNMKGNWANIIEVDYDKLRTGIGTATYLDQSVTKSKRPGIIRVNLPDKDIKN
IESAFGKKFYYSTKGNDIHTTLETPVFDLTTATDAKFDYKAFYELEAKYDFLDVYAIAEDGTKTLIDRMGEKDVKGGIDT
TDGKWIDKSYDLNQFKGKKVKLQFEYVTDIAVAYKGFALDNAALTVDGKVVFSDDAEGQPAMTLKGFTVSNGFEQKKHNY
YIEWRNYAGSDTALQYARGPVFNTGMVVWYADQSFTDNWVGVHPGEGFLGVVDSHPEAIVGTLNGQPTVKSSTRYQIADA
AFSFDQTPAWKVNSPTRGIFDYKGLPGVAKFDDSKQYINSVIPDAGRKLPKLGLKFEVVGQAEDKSAGAVWIHR

Sequences:

>Translated_794_residues
MRKKKKLKPLAVLTTAAVLSSTFAFGSHAAYADAPPSLPIDEHLIPEERLAEALKQRGVIDESASQAETSKAVEKYVEKK
KGENPGKEILTGDNLTQEASDFMKKVKDTKMQENEQAQQPEVGPVAGQSAGLNPGKLNGKVPTTPAKQAEYNGAVRKDKV
LVLLVEFSDFKHNNIDQEPGYMYSKDFNREHYQKMLFGDEPFTLFDGSKINTFKQYYEEQSGGSYTVDGTVTEWLTVPGK
ASDYGADAGTGHDNKGPLGPKDFVKEALKAAVAKGINLADYDQFDQYDQDGDGNKNEPDGIIDHLMVVHAGVGQEAGGGK
LKDDAIWSHRSKLGSKPYAIDGTKSSVSNWGGKMAAYDYTIEPEDGAVGVFAHEYGHDLGLPDEYDTKYSGQGEPVESWS
LMSGGSWAGKIAGTEPTSFSPQNKEFFQKNMKGNWANIIEVDYDKLRTGIGTATYLDQSVTKSKRPGIIRVNLPDKDIKN
IESAFGKKFYYSTKGNDIHTTLETPVFDLTTATDAKFDYKAFYELEAKYDFLDVYAIAEDGTKTLIDRMGEKDVKGGIDT
TDGKWIDKSYDLNQFKGKKVKLQFEYVTDIAVAYKGFALDNAALTVDGKVVFSDDAEGQPAMTLKGFTVSNGFEQKKHNY
YIEWRNYAGSDTALQYARGPVFNTGMVVWYADQSFTDNWVGVHPGEGFLGVVDSHPEAIVGTLNGQPTVKSSTRYQIADA
AFSFDQTPAWKVNSPTRGIFDYKGLPGVAKFDDSKQYINSVIPDAGRKLPKLGLKFEVVGQAEDKSAGAVWIHR
>Mature_794_residues
MRKKKKLKPLAVLTTAAVLSSTFAFGSHAAYADAPPSLPIDEHLIPEERLAEALKQRGVIDESASQAETSKAVEKYVEKK
KGENPGKEILTGDNLTQEASDFMKKVKDTKMQENEQAQQPEVGPVAGQSAGLNPGKLNGKVPTTPAKQAEYNGAVRKDKV
LVLLVEFSDFKHNNIDQEPGYMYSKDFNREHYQKMLFGDEPFTLFDGSKINTFKQYYEEQSGGSYTVDGTVTEWLTVPGK
ASDYGADAGTGHDNKGPLGPKDFVKEALKAAVAKGINLADYDQFDQYDQDGDGNKNEPDGIIDHLMVVHAGVGQEAGGGK
LKDDAIWSHRSKLGSKPYAIDGTKSSVSNWGGKMAAYDYTIEPEDGAVGVFAHEYGHDLGLPDEYDTKYSGQGEPVESWS
LMSGGSWAGKIAGTEPTSFSPQNKEFFQKNMKGNWANIIEVDYDKLRTGIGTATYLDQSVTKSKRPGIIRVNLPDKDIKN
IESAFGKKFYYSTKGNDIHTTLETPVFDLTTATDAKFDYKAFYELEAKYDFLDVYAIAEDGTKTLIDRMGEKDVKGGIDT
TDGKWIDKSYDLNQFKGKKVKLQFEYVTDIAVAYKGFALDNAALTVDGKVVFSDDAEGQPAMTLKGFTVSNGFEQKKHNY
YIEWRNYAGSDTALQYARGPVFNTGMVVWYADQSFTDNWVGVHPGEGFLGVVDSHPEAIVGTLNGQPTVKSSTRYQIADA
AFSFDQTPAWKVNSPTRGIFDYKGLPGVAKFDDSKQYINSVIPDAGRKLPKLGLKFEVVGQAEDKSAGAVWIHR

Specific function: Neutral metalloprotease that is secreted to degrade antibacterial proteins produced by the insect host for its defense (attacins and cecropins). Probably degrades some unknown crucial protein(s) too, since it is toxic when injected to insect larvae [H]

COG id: COG4412

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M6 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012300
- InterPro:   IPR008757 [H]

Pfam domain/function: PF05547 Peptidase_M6 [H]

EC number: NA

Molecular weight: Translated: 87292; Mature: 87292

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKKKKLKPLAVLTTAAVLSSTFAFGSHAAYADAPPSLPIDEHLIPEERLAEALKQRGVI
CCCCHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCC
DESASQAETSKAVEKYVEKKKGENPGKEILTGDNLTQEASDFMKKVKDTKMQENEQAQQP
CCCHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
EVGPVAGQSAGLNPGKLNGKVPTTPAKQAEYNGAVRKDKVLVLLVEFSDFKHNNIDQEPG
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCEEEEEEEECCCCCCCCCCCCC
YMYSKDFNREHYQKMLFGDEPFTLFDGSKINTFKQYYEEQSGGSYTVDGTVTEWLTVPGK
EEECCCCCHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHCCCCCEEECCCEEEEEECCCC
ASDYGADAGTGHDNKGPLGPKDFVKEALKAAVAKGINLADYDQFDQYDQDGDGNKNEPDG
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCCCCHH
IIDHLMVVHAGVGQEAGGGKLKDDAIWSHRSKLGSKPYAIDGTKSSVSNWGGKMAAYDYT
HHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEECCCHHHHHHCCCCEEEEEEE
IEPEDGAVGVFAHEYGHDLGLPDEYDTKYSGQGEPVESWSLMSGGSWAGKIAGTEPTSFS
ECCCCCEEEEEEHHCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCEECCCCCCCCC
PQNKEFFQKNMKGNWANIIEVDYDKLRTGIGTATYLDQSVTKSKRPGIIRVNLPDKDIKN
CCCHHHHHHHCCCCCEEEEEECHHHHHHCCCHHHHHHHHHHHCCCCCEEEEECCCHHHHH
IESAFGKKFYYSTKGNDIHTTLETPVFDLTTATDAKFDYKAFYELEAKYDFLDVYAIAED
HHHHHCCEEEEECCCCEEEEEECCCEEEEEECCCCCCCEEEEEEEECCCCEEEEEEEECC
GTKTLIDRMGEKDVKGGIDTTDGKWIDKSYDLNQFKGKKVKLQFEYVTDIAVAYKGFALD
CHHHHHHHCCCHHHCCCCCCCCCCEECCCCCHHHCCCCEEEEEEEEHHHHHHHHCCEEEC
NAALTVDGKVVFSDDAEGQPAMTLKGFTVSNGFEQKKHNYYIEWRNYAGSDTALQYARGP
CEEEEECCEEEECCCCCCCCCEEEECEEECCCCHHCCCCEEEEECCCCCCCHHHHHHCCC
VFNTGMVVWYADQSFTDNWVGVHPGEGFLGVVDSHPEAIVGTLNGQPTVKSSTRYQIADA
CCCCCEEEEEECCCCCCCCCEECCCCCEEEEECCCCCEEEECCCCCCCCCCCCCEEEEHH
AFSFDQTPAWKVNSPTRGIFDYKGLPGVAKFDDSKQYINSVIPDAGRKLPKLGLKFEVVG
HHCCCCCCCEEECCCCCCCEECCCCCCCCCCCCHHHHHHHHCCCCCCCCHHCCCEEEEEE
QAEDKSAGAVWIHR
CCCCCCCCEEEEEC
>Mature Secondary Structure
MRKKKKLKPLAVLTTAAVLSSTFAFGSHAAYADAPPSLPIDEHLIPEERLAEALKQRGVI
CCCCHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCC
DESASQAETSKAVEKYVEKKKGENPGKEILTGDNLTQEASDFMKKVKDTKMQENEQAQQP
CCCHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
EVGPVAGQSAGLNPGKLNGKVPTTPAKQAEYNGAVRKDKVLVLLVEFSDFKHNNIDQEPG
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCEEEEEEEECCCCCCCCCCCCC
YMYSKDFNREHYQKMLFGDEPFTLFDGSKINTFKQYYEEQSGGSYTVDGTVTEWLTVPGK
EEECCCCCHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHCCCCCEEECCCEEEEEECCCC
ASDYGADAGTGHDNKGPLGPKDFVKEALKAAVAKGINLADYDQFDQYDQDGDGNKNEPDG
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCCCCHH
IIDHLMVVHAGVGQEAGGGKLKDDAIWSHRSKLGSKPYAIDGTKSSVSNWGGKMAAYDYT
HHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEECCCHHHHHHCCCCEEEEEEE
IEPEDGAVGVFAHEYGHDLGLPDEYDTKYSGQGEPVESWSLMSGGSWAGKIAGTEPTSFS
ECCCCCEEEEEEHHCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCEECCCCCCCCC
PQNKEFFQKNMKGNWANIIEVDYDKLRTGIGTATYLDQSVTKSKRPGIIRVNLPDKDIKN
CCCHHHHHHHCCCCCEEEEEECHHHHHHCCCHHHHHHHHHHHCCCCCEEEEECCCHHHHH
IESAFGKKFYYSTKGNDIHTTLETPVFDLTTATDAKFDYKAFYELEAKYDFLDVYAIAED
HHHHHCCEEEEECCCCEEEEEECCCEEEEEECCCCCCCEEEEEEEECCCCEEEEEEEECC
GTKTLIDRMGEKDVKGGIDTTDGKWIDKSYDLNQFKGKKVKLQFEYVTDIAVAYKGFALD
CHHHHHHHCCCHHHCCCCCCCCCCEECCCCCHHHCCCCEEEEEEEEHHHHHHHHCCEEEC
NAALTVDGKVVFSDDAEGQPAMTLKGFTVSNGFEQKKHNYYIEWRNYAGSDTALQYARGP
CEEEEECCEEEECCCCCCCCCEEEECEEECCCCHHCCCCEEEEECCCCCCCHHHHHHCCC
VFNTGMVVWYADQSFTDNWVGVHPGEGFLGVVDSHPEAIVGTLNGQPTVKSSTRYQIADA
CCCCCEEEEEECCCCCCCCCEECCCCCEEEEECCCCCEEEECCCCCCCCCCCCCEEEEHH
AFSFDQTPAWKVNSPTRGIFDYKGLPGVAKFDDSKQYINSVIPDAGRKLPKLGLKFEVVG
HHCCCCCCCEEECCCCCCCEECCCCCCCCCCCCHHHHHHHHCCCCCCCCHHCCCEEEEEE
QAEDKSAGAVWIHR
CCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2089225; 6421577 [H]