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The map label for this gene is lcoR [H]

Identifier: 222094405

GI number: 222094405

Start: 717134

End: 717811

Strand: Reverse

Name: lcoR [H]

Synonym: BCQ_0719

Alternate gene names: 222094405

Gene position: 717811-717134 (Counterclockwise)

Preceding gene: 222094410

Following gene: 222094404

Centisome position: 13.77

GC content: 36.43

Gene sequence:

>678_bases
ATGATTGATATACTGCTCGTAGACGATGAACCGAGAATGCTTGAATTATTAACGCTTTATCTTACTCCAATTGGATATAA
CTGCATATGTGCACGATCCGGAGAAGAAGCGATTTCACATATAGAAAATCAAAACTTTAAATTTATTTTACTGGATATTA
TGATGCCAAAGATGGACGGATGGGAAACGTGTAAAAAAATCCGCTCATTTAGTAACGTTCCTATCATTATGGTAACAGCT
CGTGATCAAACGGTAGATGTCGTCCAAGGATTAAAAATCGGAGCAGATGATTACGTAACGAAACCTTTCCATGAAGAAGA
GCTTTTCGCGAGAATTGAAGCTGTTTTAAGGCGAACGAATCAACGGACGCAAATCCAATATCACGGCATTTTATGGGATG
AGGCAAAGCATTTCGTTTCTGTCTATAACGAAGAACTTCTTCTTACACCAATTGAATTCTCTTTACTCGGATTATTTTTA
CGTCATGTGAACTATGTATTGAACCGTGATCAGCTCATTGAACGAATTTGGGGATTAAATACAAATACAGAAGATAGAAC
TGTCGATTCACATATTCGTAATTTGCGTGATAAATTACGAAAAGTGAATTTCCCTATTGATGATCATTTAAAAACTGTGT
ACGGAGTTGGCTATCGATGGGTTGATACTCTAGATTAA

Upstream 100 bases:

>100_bases
AGCAATTCTGAAGAAATTATGCAGACGCATTACAATCTGCACCATTTCTTCATGATTTTGCATTACAATTTAAGTAAAGA
TTACATATGGAGGGCTCTCT

Downstream 100 bases:

>100_bases
GGAGCAAAGCAATGAAGCGAATTTCTATTCAGCTCGGATTTTATTTTTTGATTGTTACACTTTTAATCGAAAGTGTTCTA
TTTGTCTCGCTTTATTATAG

Product: response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MIDILLVDDEPRMLELLTLYLTPIGYNCICARSGEEAISHIENQNFKFILLDIMMPKMDGWETCKKIRSFSNVPIIMVTA
RDQTVDVVQGLKIGADDYVTKPFHEEELFARIEAVLRRTNQRTQIQYHGILWDEAKHFVSVYNEELLLTPIEFSLLGLFL
RHVNYVLNRDQLIERIWGLNTNTEDRTVDSHIRNLRDKLRKVNFPIDDHLKTVYGVGYRWVDTLD

Sequences:

>Translated_225_residues
MIDILLVDDEPRMLELLTLYLTPIGYNCICARSGEEAISHIENQNFKFILLDIMMPKMDGWETCKKIRSFSNVPIIMVTA
RDQTVDVVQGLKIGADDYVTKPFHEEELFARIEAVLRRTNQRTQIQYHGILWDEAKHFVSVYNEELLLTPIEFSLLGLFL
RHVNYVLNRDQLIERIWGLNTNTEDRTVDSHIRNLRDKLRKVNFPIDDHLKTVYGVGYRWVDTLD
>Mature_225_residues
MIDILLVDDEPRMLELLTLYLTPIGYNCICARSGEEAISHIENQNFKFILLDIMMPKMDGWETCKKIRSFSNVPIIMVTA
RDQTVDVVQGLKIGADDYVTKPFHEEELFARIEAVLRRTNQRTQIQYHGILWDEAKHFVSVYNEELLLTPIEFSLLGLFL
RHVNYVLNRDQLIERIWGLNTNTEDRTVDSHIRNLRDKLRKVNFPIDDHLKTVYGVGYRWVDTLD

Specific function: Member of the two-component regulatory system ArlS/ArlR involved in the regulation of adhesion, autolysis, multidrug resistance and virulence [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788394, Length=221, Percent_Identity=38.0090497737557, Blast_Score=161, Evalue=3e-41,
Organism=Escherichia coli, GI1786599, Length=223, Percent_Identity=38.5650224215247, Blast_Score=149, Evalue=1e-37,
Organism=Escherichia coli, GI87082012, Length=220, Percent_Identity=36.3636363636364, Blast_Score=138, Evalue=3e-34,
Organism=Escherichia coli, GI2367329, Length=235, Percent_Identity=37.0212765957447, Blast_Score=134, Evalue=5e-33,
Organism=Escherichia coli, GI1789809, Length=228, Percent_Identity=34.6491228070175, Blast_Score=131, Evalue=3e-32,
Organism=Escherichia coli, GI1786784, Length=221, Percent_Identity=33.4841628959276, Blast_Score=124, Evalue=7e-30,
Organism=Escherichia coli, GI1789402, Length=218, Percent_Identity=30.7339449541284, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1790552, Length=223, Percent_Identity=33.1838565022422, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1790860, Length=220, Percent_Identity=33.6363636363636, Blast_Score=121, Evalue=4e-29,
Organism=Escherichia coli, GI1786911, Length=225, Percent_Identity=31.5555555555556, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI1787229, Length=225, Percent_Identity=34.2222222222222, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1790863, Length=234, Percent_Identity=28.6324786324786, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1787375, Length=218, Percent_Identity=28.8990825688073, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI145693140, Length=232, Percent_Identity=28.448275862069, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1790437, Length=120, Percent_Identity=36.6666666666667, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1788550, Length=125, Percent_Identity=32.8, Blast_Score=74, Evalue=6e-15,
Organism=Escherichia coli, GI1788191, Length=121, Percent_Identity=29.7520661157025, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1789149, Length=108, Percent_Identity=33.3333333333333, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1788905, Length=121, Percent_Identity=31.404958677686, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI145693157, Length=100, Percent_Identity=34, Blast_Score=61, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=108, Percent_Identity=32.4074074074074, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26411; Mature: 26411

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDILLVDDEPRMLELLTLYLTPIGYNCICARSGEEAISHIENQNFKFILLDIMMPKMDG
CEEEEEECCCCHHHHHHHHHHCCCCCEEEEECCCHHHHHHHCCCCCEEEEEEEECCCCCC
WETCKKIRSFSNVPIIMVTARDQTVDVVQGLKIGADDYVTKPFHEEELFARIEAVLRRTN
HHHHHHHHCCCCCCEEEEECCCCHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
QRTQIQYHGILWDEAKHFVSVYNEELLLTPIEFSLLGLFLRHVNYVLNRDQLIERIWGLN
CCCEEEEECEEHHHHHHHHHHHCCCEEECHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCC
TNTEDRTVDSHIRNLRDKLRKVNFPIDDHLKTVYGVGYRWVDTLD
CCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCEEEEECCC
>Mature Secondary Structure
MIDILLVDDEPRMLELLTLYLTPIGYNCICARSGEEAISHIENQNFKFILLDIMMPKMDG
CEEEEEECCCCHHHHHHHHHHCCCCCEEEEECCCHHHHHHHCCCCCEEEEEEEECCCCCC
WETCKKIRSFSNVPIIMVTARDQTVDVVQGLKIGADDYVTKPFHEEELFARIEAVLRRTN
HHHHHHHHCCCCCCEEEEECCCCHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
QRTQIQYHGILWDEAKHFVSVYNEELLLTPIEFSLLGLFLRHVNYVLNRDQLIERIWGLN
CCCEEEEECEEHHHHHHHHHHHCCCEEECHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCC
TNTEDRTVDSHIRNLRDKLRKVNFPIDDHLKTVYGVGYRWVDTLD
CCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA