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The map label for this gene is accB [H]

Identifier: 221636177

GI number: 221636177

Start: 751968

End: 752216

Strand: Reverse

Name: accB [H]

Synonym: trd_A0771

Alternate gene names: 221636177

Gene position: 752216-751968 (Counterclockwise)

Preceding gene: 221636178

Following gene: 221636176

Centisome position: 81.96

GC content: 63.05

Gene sequence:

>249_bases
ATGGCGGAGCACACGATCAAATCACCGTTGCCAGGCATCTTTTATCGGCGACCCAGCCCGGATGCGGCGCCGTTCGTCGA
GGAAGGACAGACGATCCAACCGGGGACGGTCATCGGCCTGGTCGGTGTGATGAAGACGTTCCACCAGATCACGGCCGATG
TCGGCGGGAAACTGGTGCGCTTCCTGGTGGAGAACGAAGAGGCGATCCGACCCGGCCAACCGATCGCGGTGGTGAGCGAC
GAGGCCTGA

Upstream 100 bases:

>100_bases
ACCTACACGCAGTTGATCATCACGGGCGCGCTGCTGGTCGTGGCAGTGATCATCGATAACTGGGTGCATCGTGAGCGGTA
GGACGGGAAGGGGGAACGTG

Downstream 100 bases:

>100_bases
CCCCGGTAGGCAGCGGAAGGAGCGAGCGGTCATGATGGGCACTGGTCCTCATCCCTCAGGAGTGGTCCTGGCGAGCTTCC
CGGAGCGGAACGGCCGCCCG

Product: biotin carboxyl carrier protein of acetyl-coa carboxylase (bccp)

Products: Malonyl-CoA; malonyl-CoA; phosphate; ADP [C]

Alternate protein names: BCCP [H]

Number of amino acids: Translated: 82; Mature: 81

Protein sequence:

>82_residues
MAEHTIKSPLPGIFYRRPSPDAAPFVEEGQTIQPGTVIGLVGVMKTFHQITADVGGKLVRFLVENEEAIRPGQPIAVVSD
EA

Sequences:

>Translated_82_residues
MAEHTIKSPLPGIFYRRPSPDAAPFVEEGQTIQPGTVIGLVGVMKTFHQITADVGGKLVRFLVENEEAIRPGQPIAVVSD
EA
>Mature_81_residues
AEHTIKSPLPGIFYRRPSPDAAPFVEEGQTIQPGTVIGLVGVMKTFHQITADVGGKLVRFLVENEEAIRPGQPIAVVSDE
A

Specific function: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA [H]

COG id: COG0511

COG function: function code I; Biotin carboxyl carrier protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 biotinyl-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789653, Length=75, Percent_Identity=40, Blast_Score=66, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001249
- InterPro:   IPR001882
- InterPro:   IPR000089
- InterPro:   IPR011053 [H]

Pfam domain/function: PF00364 Biotin_lipoyl [H]

EC number: NA

Molecular weight: Translated: 8826; Mature: 8695

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: PS50968 BIOTINYL_LIPOYL ; PS00188 BIOTIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEHTIKSPLPGIFYRRPSPDAAPFVEEGQTIQPGTVIGLVGVMKTFHQITADVGGKLVR
CCCCCCCCCCCCEEEECCCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
FLVENEEAIRPGQPIAVVSDEA
HHHCCCCCCCCCCCEEEEECCC
>Mature Secondary Structure 
AEHTIKSPLPGIFYRRPSPDAAPFVEEGQTIQPGTVIGLVGVMKTFHQITADVGGKLVR
CCCCCCCCCCCEEEECCCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
FLVENEEAIRPGQPIAVVSDEA
HHHCCCCCCCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Acetyl-CoA; HCO3-; Proton; acetyl-CoA; ATP [C]

Specific reaction: acetyl-CoA = malonyl-CoA HCO3- + Proton + acetyl-CoA + ATP = malonyl-CoA + phosphate + ADP [C]

General reaction: Ligases; Forming Carbon-Carbon Bonds; acetyl-CoA carboxylase Reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7592499; 8969508; 9384377 [H]