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The map label for this gene is degQ [H]

Identifier: 221636012

GI number: 221636012

Start: 596904

End: 598061

Strand: Reverse

Name: degQ [H]

Synonym: trd_A0606

Alternate gene names: 221636012

Gene position: 598061-596904 (Counterclockwise)

Preceding gene: 221636013

Following gene: 221636011

Centisome position: 65.17

GC content: 65.28

Gene sequence:

>1158_bases
ATGGAGCAGAGGAGTTCGGTAAGACAGCGGATTCTGCCGCTCTTGGTCGTGATCGGATTCCTGATAGCCGGAGTGATCGG
GGGCCTGGCGGGGGCCTCGCTCGCTGGCGAGCGGGGAGCCGGCAGGTCGACGGTCTCGATTGCGGTGACCGCTCCGGCTG
AATCTCACCCGCAACCGGTCGCCGAGGTGCAGGCGACGACGGTTGCTGGGCAGGTGTACCAGCGTTACGGGAAAGCCGTC
GTCGATGTGATCGCGCAGACATCGAACGGCTTCTTCGACGAGCAAGGCGCTGGTAGCGGTGTCGTGATCGACCAACGGGG
GCTCATCGTCACGGCTGCTCACGTGGTCGCGGGAACGAGCACAGTGGAAATTCGCTTCGGAACGGGTGAGCGTGTTTCGG
CACAGGTGCTGGGTACCGACGAGGCGAACGATATCGCCCTGCTTCGCGTCGACCGCCTTCCCGAAGGAGTGCCGGTGGCG
GTGCTCGGCGACTCCGACCGCGTCCAAGTCGGCGATGTGGTGGTCGCGATCGGCAATCCCTTCGGTCTCTCTGGTACGGT
CACCCAAGGGATCGTCAGTGCCGTGAACCGGAGCTGGAACCCACCGGGTGATCGGTTACGGACGGGACTGATCCAGACCG
ATGCACCGATCAATCCCGGCAATAGCGGCGGGCCGCTCTTCGATGCCCAGGGCGAAGTGATCGGCATCACCACTATGATC
GAGAGCCCGATCCGAGGAAACGTCGGCATCGGCTTCGCCGTTCCGAGCAACACGGTGAAGCGCGTGCTGCCGCAGCTCGA
GCAAGGTGCGCAGCTCGAGCCCGCCTGGCTGGGCATTAGCGGGACCGATCTCGACGCGCAGCGGGCGCGCCGATTCGGAC
TGTCGGTCGACCGAGGGGTCATCGTCCTGAGCGTGGTACCGGGAAGCCCGGCAGCACGAGCTGGATTACGTCCGGCGCAA
ATGAGTGGATTGGACATCACCCAGCTGGGCGACGTGATCGTGGCGATCGATGGTCAGCCCGTCGCGGGAATGCAGGATCT
GGCGGCGCGGATCGGCGCACATCAGCCGGGCGACACGGTCGAGCTGACAGTGTTGCGCGATGGACGCCAGCAGACCGTTC
GGGTCACACTCGGCCGCTGGCCTCAGCAGCAGGGATGA

Upstream 100 bases:

>100_bases
GAGATTCTCAGCTGGATCTTGCCTGATTTTGATCCGCAGCCGGTAGGCTCAGAGCGGAAGCACCGGTGTGCGCGGTGCAG
GATGTGCTGGAGGATGCACG

Downstream 100 bases:

>100_bases
CCTTGACGCTGGCGTACGGTGTGTGCTAGTATATGTAGGTTTCGAAACGTCGTCGTGCGGTGTCCGTACGACGCGTCCGA
ACAACGGAGGTACGAGAGAC

Product: trypsin domain protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
MEQRSSVRQRILPLLVVIGFLIAGVIGGLAGASLAGERGAGRSTVSIAVTAPAESHPQPVAEVQATTVAGQVYQRYGKAV
VDVIAQTSNGFFDEQGAGSGVVIDQRGLIVTAAHVVAGTSTVEIRFGTGERVSAQVLGTDEANDIALLRVDRLPEGVPVA
VLGDSDRVQVGDVVVAIGNPFGLSGTVTQGIVSAVNRSWNPPGDRLRTGLIQTDAPINPGNSGGPLFDAQGEVIGITTMI
ESPIRGNVGIGFAVPSNTVKRVLPQLEQGAQLEPAWLGISGTDLDAQRARRFGLSVDRGVIVLSVVPGSPAARAGLRPAQ
MSGLDITQLGDVIVAIDGQPVAGMQDLAARIGAHQPGDTVELTVLRDGRQQTVRVTLGRWPQQQG

Sequences:

>Translated_385_residues
MEQRSSVRQRILPLLVVIGFLIAGVIGGLAGASLAGERGAGRSTVSIAVTAPAESHPQPVAEVQATTVAGQVYQRYGKAV
VDVIAQTSNGFFDEQGAGSGVVIDQRGLIVTAAHVVAGTSTVEIRFGTGERVSAQVLGTDEANDIALLRVDRLPEGVPVA
VLGDSDRVQVGDVVVAIGNPFGLSGTVTQGIVSAVNRSWNPPGDRLRTGLIQTDAPINPGNSGGPLFDAQGEVIGITTMI
ESPIRGNVGIGFAVPSNTVKRVLPQLEQGAQLEPAWLGISGTDLDAQRARRFGLSVDRGVIVLSVVPGSPAARAGLRPAQ
MSGLDITQLGDVIVAIDGQPVAGMQDLAARIGAHQPGDTVELTVLRDGRQQTVRVTLGRWPQQQG
>Mature_385_residues
MEQRSSVRQRILPLLVVIGFLIAGVIGGLAGASLAGERGAGRSTVSIAVTAPAESHPQPVAEVQATTVAGQVYQRYGKAV
VDVIAQTSNGFFDEQGAGSGVVIDQRGLIVTAAHVVAGTSTVEIRFGTGERVSAQVLGTDEANDIALLRVDRLPEGVPVA
VLGDSDRVQVGDVVVAIGNPFGLSGTVTQGIVSAVNRSWNPPGDRLRTGLIQTDAPINPGNSGGPLFDAQGEVIGITTMI
ESPIRGNVGIGFAVPSNTVKRVLPQLEQGAQLEPAWLGISGTDLDAQRARRFGLSVDRGVIVLSVVPGSPAARAGLRPAQ
MSGLDITQLGDVIVAIDGQPVAGMQDLAARIGAHQPGDTVELTVLRDGRQQTVRVTLGRWPQQQG

Specific function: Protease with a shared specificity with degP [H]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=264, Percent_Identity=36.7424242424242, Blast_Score=145, Evalue=5e-35,
Organism=Homo sapiens, GI22129776, Length=303, Percent_Identity=32.6732673267327, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI24308541, Length=282, Percent_Identity=33.3333333333333, Blast_Score=126, Evalue=3e-29,
Organism=Homo sapiens, GI7019477, Length=294, Percent_Identity=36.734693877551, Blast_Score=122, Evalue=6e-28,
Organism=Escherichia coli, GI1786356, Length=289, Percent_Identity=41.1764705882353, Blast_Score=207, Evalue=1e-54,
Organism=Escherichia coli, GI1789629, Length=285, Percent_Identity=41.4035087719298, Blast_Score=204, Evalue=6e-54,
Organism=Escherichia coli, GI1789630, Length=320, Percent_Identity=32.5, Blast_Score=159, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24646839, Length=298, Percent_Identity=31.5436241610738, Blast_Score=128, Evalue=7e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 39783; Mature: 39783

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQRSSVRQRILPLLVVIGFLIAGVIGGLAGASLAGERGAGRSTVSIAVTAPAESHPQPV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCCCCCCCH
AEVQATTVAGQVYQRYGKAVVDVIAQTSNGFFDEQGAGSGVVIDQRGLIVTAAHVVAGTS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCEEEEEEHHHCCCE
TVEIRFGTGERVSAQVLGTDEANDIALLRVDRLPEGVPVAVLGDSDRVQVGDVVVAIGNP
EEEEEECCCCEEEEEEECCCCCCCEEEEEECCCCCCCCEEEECCCCCEEECCEEEEECCC
FGLSGTVTQGIVSAVNRSWNPPGDRLRTGLIQTDAPINPGNSGGPLFDAQGEVIGITTMI
CCCCCHHHHHHHHHHHCCCCCCHHHHHHCEEECCCCCCCCCCCCCEEECCCCEEEEEEEE
ESPIRGNVGIGFAVPSNTVKRVLPQLEQGAQLEPAWLGISGTDLDAQRARRFGLSVDRGV
CCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHHCCCCCCCE
IVLSVVPGSPAARAGLRPAQMSGLDITQLGDVIVAIDGQPVAGMQDLAARIGAHQPGDTV
EEEEECCCCCHHHCCCCCHHCCCCCHHHCCCEEEEECCCCCCCHHHHHHHHCCCCCCCEE
ELTVLRDGRQQTVRVTLGRWPQQQG
EEEEEECCCCEEEEEEECCCCCCCC
>Mature Secondary Structure
MEQRSSVRQRILPLLVVIGFLIAGVIGGLAGASLAGERGAGRSTVSIAVTAPAESHPQPV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCCCCCCCH
AEVQATTVAGQVYQRYGKAVVDVIAQTSNGFFDEQGAGSGVVIDQRGLIVTAAHVVAGTS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCEEEEEEHHHCCCE
TVEIRFGTGERVSAQVLGTDEANDIALLRVDRLPEGVPVAVLGDSDRVQVGDVVVAIGNP
EEEEEECCCCEEEEEEECCCCCCCEEEEEECCCCCCCCEEEECCCCCEEECCEEEEECCC
FGLSGTVTQGIVSAVNRSWNPPGDRLRTGLIQTDAPINPGNSGGPLFDAQGEVIGITTMI
CCCCCHHHHHHHHHHHCCCCCCHHHHHHCEEECCCCCCCCCCCCCEEECCCCEEEEEEEE
ESPIRGNVGIGFAVPSNTVKRVLPQLEQGAQLEPAWLGISGTDLDAQRARRFGLSVDRGV
CCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHHCCCCCCCE
IVLSVVPGSPAARAGLRPAQMSGLDITQLGDVIVAIDGQPVAGMQDLAARIGAHQPGDTV
EEEEECCCCCHHHCCCCCHHCCCCCHHHCCCEEEEECCCCCCCHHHHHHHHCCCCCCCEE
ELTVLRDGRQQTVRVTLGRWPQQQG
EEEEEECCCCEEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Serine endopeptidases [C]

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8576051; 9278503 [H]