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The map label for this gene is ykoH [H]

Identifier: 221636013

GI number: 221636013

Start: 598179

End: 599618

Strand: Reverse

Name: ykoH [H]

Synonym: trd_A0607

Alternate gene names: 221636013

Gene position: 599618-598179 (Counterclockwise)

Preceding gene: 221636014

Following gene: 221636012

Centisome position: 65.34

GC content: 64.31

Gene sequence:

>1440_bases
ATGTCGATCCGGCTGCGTTTGACGCTGCTCTACAGTGGGATCCTGGTCTGCACGCTGGTGATCTTTAGCGTCGTGCTCTA
CGTGCTGGTTGCCCGCTTCAGTCTGCAATGGCAAGAGCGAGCACTGGCCGAGGAAGCGGCCCAGATCGTCACGCAAGGTG
AGTTTCGCCTGACGGTGATTCGGACGCCGCAGGGCAAGGTGGCGATACCGCAAACCTTCGTGCAGACGCGCGATCTTTCC
GGGCAAGTGATCTCGCGCTCGATCAACTTGAACGGTTACGAATTGCCGCTCAGCAGTCAGGGCCTCACAGCTCTGACGAA
CGGACAGGCGACCGGCTGGTTGGAGATCGTGCGGACCGACAATGGGCGCCTGCTCGTGTACAGTCGGACGGTCACGGCCA
ACGGCCAGCCGGTCGGCATTCTGCAGGTGGCGCGACCGCTCGCCGATCTCGATCAAGCGCTCGCGATGCTGCGCCGCTAC
TTGACGGTCGGCACCGTGGTGTCAACGATCACTGCCTTTTTCGTCGGCTGGGTATTGGCTGGCGCGAGCCTGCGGCCGAT
CAATCGGATCACACAGATCGCTCGGGAAATCGGGCAGGCGCGTGACTTCAGCCGACGAGTGGACTACGACGGACCGAACG
ACGAGATCGGTGCGCTGGTGACGACACTGAACGAGATGCTGACCGAGCTCCAGGCGGCCTATCAGCAAGTCGAGCATGCC
CTGCAAGCACAGCGCCGGTTCGTGGCGGATGCCTCTCACGAGCTGCGTACACCACTGACCACCTTACGGGGGAACGTCGA
ACTCTTGCAACGGGAGCCCCCGCTTCCTCTCGAGGAACAGCGAGCGATCCTGGCGGACGTCGCGGCGGAGATCGAACGGA
TGATTCGGCTGGTCCGCGAACTGTTGACGCTGGCGCGAGCCGACGCTGGTCTCCGCCCACGGCTGGAGCCGGTGCAGCTG
GGGTCGCTCGTGGAGGATGCAGTTCGGCAAGCGCAACTCTTGCGACCGCGACCGGTCGCCAGGGTGCGAGTGGAGCGCGA
CGTCGTCGTGCGGGCTGATCGGGATCTCCTCTATCAGGTGCTGTTGATCCTTCTGGACAACGCGCTGAAGTACACGCCGG
AGGACGGCATGGTGGAGGCGACGGTCGTCGTGGAGCAGGGTCGCGCGGGTATCGCGGTCCGAGATACGGGGATCGGCATC
GACCCCGCGATCATGCCGCACATCTTCGAGCGTTTCTTCCGCGGCGACAGTGCCCGGAGTGGCGAGGGGACCGGCCTGGG
ACTCGCGATCGCGAAATCGCTGTTGGAGGCGATGCGCGGCGAAATTCGCGTGGTGAGTCGACCCGGCGAGGGGAGCATCT
TCACGGTATTGCTCCCGGTCGAACCAGCGAGCGCGGAAGGCGAAGCTCAAGCGGCGCCAAGCCTCGTGTCTCCCGCGTAG

Upstream 100 bases:

>100_bases
CATCGGCTATCTCCGACAGAAGCTGGAGGCCGGTGGGGAGCCCCGACTGATCCATACCGTCCGGGGTGTGGGCTATGTGT
TGCGGGAGTCCTGAGGAGAA

Downstream 100 bases:

>100_bases
TCGCCGACGATTCTCAGGAGATTCTCAGCTGGATCTTGCCTGATTTTGATCCGCAGCCGGTAGGCTCAGAGCGGAAGCAC
CGGTGTGCGCGGTGCAGGAT

Product: sensor protein CutS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 479; Mature: 478

Protein sequence:

>479_residues
MSIRLRLTLLYSGILVCTLVIFSVVLYVLVARFSLQWQERALAEEAAQIVTQGEFRLTVIRTPQGKVAIPQTFVQTRDLS
GQVISRSINLNGYELPLSSQGLTALTNGQATGWLEIVRTDNGRLLVYSRTVTANGQPVGILQVARPLADLDQALAMLRRY
LTVGTVVSTITAFFVGWVLAGASLRPINRITQIAREIGQARDFSRRVDYDGPNDEIGALVTTLNEMLTELQAAYQQVEHA
LQAQRRFVADASHELRTPLTTLRGNVELLQREPPLPLEEQRAILADVAAEIERMIRLVRELLTLARADAGLRPRLEPVQL
GSLVEDAVRQAQLLRPRPVARVRVERDVVVRADRDLLYQVLLILLDNALKYTPEDGMVEATVVVEQGRAGIAVRDTGIGI
DPAIMPHIFERFFRGDSARSGEGTGLGLAIAKSLLEAMRGEIRVVSRPGEGSIFTVLLPVEPASAEGEAQAAPSLVSPA

Sequences:

>Translated_479_residues
MSIRLRLTLLYSGILVCTLVIFSVVLYVLVARFSLQWQERALAEEAAQIVTQGEFRLTVIRTPQGKVAIPQTFVQTRDLS
GQVISRSINLNGYELPLSSQGLTALTNGQATGWLEIVRTDNGRLLVYSRTVTANGQPVGILQVARPLADLDQALAMLRRY
LTVGTVVSTITAFFVGWVLAGASLRPINRITQIAREIGQARDFSRRVDYDGPNDEIGALVTTLNEMLTELQAAYQQVEHA
LQAQRRFVADASHELRTPLTTLRGNVELLQREPPLPLEEQRAILADVAAEIERMIRLVRELLTLARADAGLRPRLEPVQL
GSLVEDAVRQAQLLRPRPVARVRVERDVVVRADRDLLYQVLLILLDNALKYTPEDGMVEATVVVEQGRAGIAVRDTGIGI
DPAIMPHIFERFFRGDSARSGEGTGLGLAIAKSLLEAMRGEIRVVSRPGEGSIFTVLLPVEPASAEGEAQAAPSLVSPA
>Mature_478_residues
SIRLRLTLLYSGILVCTLVIFSVVLYVLVARFSLQWQERALAEEAAQIVTQGEFRLTVIRTPQGKVAIPQTFVQTRDLSG
QVISRSINLNGYELPLSSQGLTALTNGQATGWLEIVRTDNGRLLVYSRTVTANGQPVGILQVARPLADLDQALAMLRRYL
TVGTVVSTITAFFVGWVLAGASLRPINRITQIAREIGQARDFSRRVDYDGPNDEIGALVTTLNEMLTELQAAYQQVEHAL
QAQRRFVADASHELRTPLTTLRGNVELLQREPPLPLEEQRAILADVAAEIERMIRLVRELLTLARADAGLRPRLEPVQLG
SLVEDAVRQAQLLRPRPVARVRVERDVVVRADRDLLYQVLLILLDNALKYTPEDGMVEATVVVEQGRAGIAVRDTGIGID
PAIMPHIFERFFRGDSARSGEGTGLGLAIAKSLLEAMRGEIRVVSRPGEGSIFTVLLPVEPASAEGEAQAAPSLVSPA

Specific function: Probable member of the two-component regulatory system ykoH/ykoG. Potentially phosphorylates ykoG [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=269, Percent_Identity=30.8550185873606, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1786600, Length=269, Percent_Identity=32.3420074349442, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI87082128, Length=284, Percent_Identity=30.2816901408451, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1788393, Length=286, Percent_Identity=32.5174825174825, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI1786783, Length=366, Percent_Identity=27.5956284153005, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI145693157, Length=249, Percent_Identity=33.3333333333333, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI87081816, Length=258, Percent_Identity=31.3953488372093, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI1788713, Length=253, Percent_Identity=28.4584980237154, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI1788279, Length=310, Percent_Identity=26.7741935483871, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI1786912, Length=253, Percent_Identity=32.0158102766798, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1790436, Length=220, Percent_Identity=32.2727272727273, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1789403, Length=262, Percent_Identity=32.0610687022901, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1790861, Length=308, Percent_Identity=28.2467532467532, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1790551, Length=246, Percent_Identity=31.3008130081301, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1790346, Length=291, Percent_Identity=26.4604810996564, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1787894, Length=246, Percent_Identity=31.7073170731707, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1789149, Length=244, Percent_Identity=29.9180327868852, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI48994928, Length=259, Percent_Identity=27.7992277992278, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1789808, Length=328, Percent_Identity=24.6951219512195, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1790300, Length=264, Percent_Identity=31.4393939393939, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1787374, Length=268, Percent_Identity=25.3731343283582, Blast_Score=63, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 52535; Mature: 52403

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIRLRLTLLYSGILVCTLVIFSVVLYVLVARFSLQWQERALAEEAAQIVTQGEFRLTVI
CCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEE
RTPQGKVAIPQTFVQTRDLSGQVISRSINLNGYELPLSSQGLTALTNGQATGWLEIVRTD
ECCCCCEECCHHHHHHCCCCCHHHHEEECCCCEECCCCCCCCEEEECCCCCCEEEEEEEC
NGRLLVYSRTVTANGQPVGILQVARPLADLDQALAMLRRYLTVGTVVSTITAFFVGWVLA
CCEEEEEEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GASLRPINRITQIAREIGQARDFSRRVDYDGPNDEIGALVTTLNEMLTELQAAYQQVEHA
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQAQRRFVADASHELRTPLTTLRGNVELLQREPPLPLEEQRAILADVAAEIERMIRLVRE
HHHHHHHHHCCHHHHHCCHHHHCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LLTLARADAGLRPRLEPVQLGSLVEDAVRQAQLLRPRPVARVRVERDVVVRADRDLLYQV
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHEEECCCEEEECCHHHHHHH
LLILLDNALKYTPEDGMVEATVVVEQGRAGIAVRDTGIGIDPAIMPHIFERFFRGDSARS
HHHHHHHHHCCCCCCCCEEEEEEEECCCCCEEEECCCCCCCHHHHHHHHHHHHCCCCCCC
GEGTGLGLAIAKSLLEAMRGEIRVVSRPGEGSIFTVLLPVEPASAEGEAQAAPSLVSPA
CCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SIRLRLTLLYSGILVCTLVIFSVVLYVLVARFSLQWQERALAEEAAQIVTQGEFRLTVI
CEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEE
RTPQGKVAIPQTFVQTRDLSGQVISRSINLNGYELPLSSQGLTALTNGQATGWLEIVRTD
ECCCCCEECCHHHHHHCCCCCHHHHEEECCCCEECCCCCCCCEEEECCCCCCEEEEEEEC
NGRLLVYSRTVTANGQPVGILQVARPLADLDQALAMLRRYLTVGTVVSTITAFFVGWVLA
CCEEEEEEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GASLRPINRITQIAREIGQARDFSRRVDYDGPNDEIGALVTTLNEMLTELQAAYQQVEHA
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQAQRRFVADASHELRTPLTTLRGNVELLQREPPLPLEEQRAILADVAAEIERMIRLVRE
HHHHHHHHHCCHHHHHCCHHHHCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LLTLARADAGLRPRLEPVQLGSLVEDAVRQAQLLRPRPVARVRVERDVVVRADRDLLYQV
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHEEECCCEEEECCHHHHHHH
LLILLDNALKYTPEDGMVEATVVVEQGRAGIAVRDTGIGIDPAIMPHIFERFFRGDSARS
HHHHHHHHHCCCCCCCCEEEEEEEECCCCCEEEECCCCCCCHHHHHHHHHHHHCCCCCCC
GEGTGLGLAIAKSLLEAMRGEIRVVSRPGEGSIFTVLLPVEPASAEGEAQAAPSLVSPA
CCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]