Click here to switch to the map view.

The map label for this gene is dacC [H]

Identifier: 221635723

GI number: 221635723

Start: 303190

End: 304161

Strand: Reverse

Name: dacC [H]

Synonym: trd_A0317

Alternate gene names: 221635723

Gene position: 304161-303190 (Counterclockwise)

Preceding gene: 221635724

Following gene: 221635721

Centisome position: 33.14

GC content: 66.67

Gene sequence:

>972_bases
GTGAGGGGCTTCTTCGCTTTTGTCCGCCGCTTCGGCGTTCCCTTCGGTCTGCTCGCTCTGAGTGTCGCGATCGCTGGCGC
GACACTGGCGCGCTACGCAGCCCCAGTCAGTCTACCGTCCACCACAACGGTCGCACCCTCACCCGAACCGACACCGACCC
CCACGCCGACACCGTCTCCGACTCCCGAACCACCCTCGCTCAGCGCCCGCTCCGTCCTCGTCGTCGATCTCACCACCGAC
CGGATCCTCCTGGAGCGTGCCAGCCGGACACCCCTTCCTCCAGCCAGTACTCTCAAGCTCCTCACCGCGCTGACTGCAGT
GGAGATCCTCTCATTCGAAGAAATCGTCACGGTCCAGCCGGAGGACACGGTCGATCCAGCCCGTGAATCGGCCATGGGAC
TGGACGTTGGAGACACGATCACGGTCCATGACCTCCTGCTTGGCCTACTCCTCCCCTCCGGCAATGACGCCGCCCGGGCA
CTGGCCCGCAGCGCTGGCGAGCGACTCGCTGGTCCCCCCGATCGACCACCGCGCGAGCGCTTCCTCGTCGCGATGCAGGA
GAAAGCTCGGGAACTTGGCCTCAGCGAAACGGTCGTGCTGACACCGGACGGCGACGACGTACCCGGGCAGACGACGAGTG
CGCGTGACCTTCTCCAGCTCGCCCGCGCGACACTCGACCATCCGGAACTCGCCGCTCTCGTCGCCCTGCGCACGGCGCAG
GTCCGCGTCGGTGGTCCGAAGGCGCGCGTGCTCGAACTCCGGAACACGAACGAACTCCTCGGTCAACACGGAGTCATCGG
GATCAAAACCGGAACGACTCCCGAGGCCGGGCAGTGTCTGGTCGCTGCGTGGCGCACCAGTGACGGACGGACCTTCGTTG
CCATCGTCCTCGGGAGCCAGGATCGCTACGGTGACATGCGGGCGATCATCGATTGGGTCGCGCGGACAACCGGTAGCGCG
CCGGTCCCATGA

Upstream 100 bases:

>100_bases
GGTCGCGACTTCCCGCGCTCGTCCGCACCTGGCCAGAAGCACGGTCTGCCCAGTCACTCGCCCTTCCCCCAGATGGCATG
ACGAGCGTGGGAGCACCGCA

Downstream 100 bases:

>100_bases
TTCGCCGCGAAGAGTGCCGGGGTGGCCGGGGACTCCGGCGCCGCTCTCATCCGGTCGATCACGGTTCACCCATGCCGGTC
GGGACCAGGTAGTCCGGCGA

Product: D,D carboxypeptidase

Products: NA

Alternate protein names: DD-carboxypeptidase; DD-peptidase; Penicillin-binding protein 6; PBP-6 [H]

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MRGFFAFVRRFGVPFGLLALSVAIAGATLARYAAPVSLPSTTTVAPSPEPTPTPTPTPSPTPEPPSLSARSVLVVDLTTD
RILLERASRTPLPPASTLKLLTALTAVEILSFEEIVTVQPEDTVDPARESAMGLDVGDTITVHDLLLGLLLPSGNDAARA
LARSAGERLAGPPDRPPRERFLVAMQEKARELGLSETVVLTPDGDDVPGQTTSARDLLQLARATLDHPELAALVALRTAQ
VRVGGPKARVLELRNTNELLGQHGVIGIKTGTTPEAGQCLVAAWRTSDGRTFVAIVLGSQDRYGDMRAIIDWVARTTGSA
PVP

Sequences:

>Translated_323_residues
MRGFFAFVRRFGVPFGLLALSVAIAGATLARYAAPVSLPSTTTVAPSPEPTPTPTPTPSPTPEPPSLSARSVLVVDLTTD
RILLERASRTPLPPASTLKLLTALTAVEILSFEEIVTVQPEDTVDPARESAMGLDVGDTITVHDLLLGLLLPSGNDAARA
LARSAGERLAGPPDRPPRERFLVAMQEKARELGLSETVVLTPDGDDVPGQTTSARDLLQLARATLDHPELAALVALRTAQ
VRVGGPKARVLELRNTNELLGQHGVIGIKTGTTPEAGQCLVAAWRTSDGRTFVAIVLGSQDRYGDMRAIIDWVARTTGSA
PVP
>Mature_323_residues
MRGFFAFVRRFGVPFGLLALSVAIAGATLARYAAPVSLPSTTTVAPSPEPTPTPTPTPSPTPEPPSLSARSVLVVDLTTD
RILLERASRTPLPPASTLKLLTALTAVEILSFEEIVTVQPEDTVDPARESAMGLDVGDTITVHDLLLGLLLPSGNDAARA
LARSAGERLAGPPDRPPRERFLVAMQEKARELGLSETVVLTPDGDDVPGQTTSARDLLQLARATLDHPELAALVALRTAQ
VRVGGPKARVLELRNTNELLGQHGVIGIKTGTTPEAGQCLVAAWRTSDGRTFVAIVLGSQDRYGDMRAIIDWVARTTGSA
PVP

Specific function: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors [H]

COG id: COG1686

COG function: function code M; D-alanyl-D-alanine carboxypeptidase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein. Note=N-terminal lies in the periplasmic space [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S11 family [H]

Homologues:

Organism=Escherichia coli, GI1787062, Length=270, Percent_Identity=33.3333333333333, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI87082022, Length=271, Percent_Identity=31.7343173431734, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI87082054, Length=269, Percent_Identity=29.368029739777, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1786851, Length=268, Percent_Identity=29.4776119402985, Blast_Score=73, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR015956
- InterPro:   IPR018044
- InterPro:   IPR012907
- InterPro:   IPR001967 [H]

Pfam domain/function: PF07943 PBP5_C; PF00768 Peptidase_S11 [H]

EC number: =3.4.16.4 [H]

Molecular weight: Translated: 34100; Mature: 34100

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGFFAFVRRFGVPFGLLALSVAIAGATLARYAAPVSLPSTTTVAPSPEPTPTPTPTPSP
CCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCCCCCCCCCCCC
TPEPPSLSARSVLVVDLTTDRILLERASRTPLPPASTLKLLTALTAVEILSFEEIVTVQP
CCCCCCCCCCEEEEEEECCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEECC
EDTVDPARESAMGLDVGDTITVHDLLLGLLLPSGNDAARALARSAGERLAGPPDRPPRER
CCCCCHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCHHH
FLVAMQEKARELGLSETVVLTPDGDDVPGQTTSARDLLQLARATLDHPELAALVALRTAQ
HHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHE
VRVGGPKARVLELRNTNELLGQHGVIGIKTGTTPEAGQCLVAAWRTSDGRTFVAIVLGSQ
EEECCCCEEEEEECCCHHHHHCCCEEEEECCCCCCCCCEEEEEEECCCCCEEEEEEECCC
DRYGDMRAIIDWVARTTGSAPVP
CCCCHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MRGFFAFVRRFGVPFGLLALSVAIAGATLARYAAPVSLPSTTTVAPSPEPTPTPTPTPSP
CCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCCCCCCCCCCCC
TPEPPSLSARSVLVVDLTTDRILLERASRTPLPPASTLKLLTALTAVEILSFEEIVTVQP
CCCCCCCCCCEEEEEEECCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEECC
EDTVDPARESAMGLDVGDTITVHDLLLGLLLPSGNDAARALARSAGERLAGPPDRPPRER
CCCCCHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCHHH
FLVAMQEKARELGLSETVVLTPDGDDVPGQTTSARDLLQLARATLDHPELAALVALRTAQ
HHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHE
VRVGGPKARVLELRNTNELLGQHGVIGIKTGTTPEAGQCLVAAWRTSDGRTFVAIVLGSQ
EEECCCCEEEEEECCCHHHHHCCCEEEEECCCCCCCCCEEEEEEECCCCCEEEEEEECCC
DRYGDMRAIIDWVARTTGSAPVP
CCCCHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 3279397; 8905232; 9278503; 7042389 [H]