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The map label for this gene is hyuA [H]

Identifier: 221633828

GI number: 221633828

Start: 1866491

End: 1868035

Strand: Reverse

Name: hyuA [H]

Synonym: trd_1855

Alternate gene names: 221633828

Gene position: 1868035-1866491 (Counterclockwise)

Preceding gene: 221633829

Following gene: 221633827

Centisome position: 93.26

GC content: 66.8

Gene sequence:

>1545_bases
GTGGCGCGATTGGGCATCGACGTCGGTGGCACGAATACCGACGCGGTCCTTTTGGACCGCAGTGAGGTCCTCGCCTGGGC
CAAGGAACCGACGACACCGGACGTGAGCACCGGCATCTTGCGCGTGGTACGCGATGTCCTGGCGCAGGCTCGGATCGCCC
CGGACGAGATCCGCGCCGTGATGCTCGGGACAACCCACTTCACCAATGCCGTCGTGCAGCGGCAGGAACTCGCCCGCATC
GCCGTGCTCCGCCTCGGTCTTCCAGCGACCGCATCCATCCCACCACTCGAGGATTGGCCCGATGATCTCCGCGATGCCGT
CGCGGGATTCATCGCGCTCCTTCCCGGCGGACACCAGTTCGATGGCCGCGAGATCAGTCCGCTGGATCACTCGGCACTGA
ACCAGGTCTGCGAACGGATCGCCGAACTGGGAATCAGTTCCGCGGCGGTCACCGCCGTCTTCTCGCCAGCAACATCTGCC
CACGAGGATGCGGTGGCCGACTTGCTCGCCAGCCGAGTGCCAGGACTCCGCATCACCCGCTCCCGCGAGATCGGGCGCCT
CGGACTTCTCGAACGCGAGAATGCCGCTGCCCTCAATGCCTGCCTGGTGCCACTCGCCGAGCGGACGATCCGGGCGTTCC
AGGACGCACTCGCCGAACTCGGGCTGACGGCACCGCTCTACCTCAGCCAGAACGATGGCACGCTCATGACAGCCGATTTC
GCCACACGCTATCCTGTCCTCACCTTCGCGTCGGGACCGACCAACTCGATGCGCGGCGCGGCTGTCCTCAGCGGTCTGCG
CGATGCCATCGTTCTGGACGTCGGCGGGACGACGACCGATGGTGGTGCCCTGGTCAACGGCTTCCCTCGCGAGGCATCAT
TCGCGGTCACGATCGGTGGCGTCCGCACCAACTTTCGCATGCCGGACGTCGTGTCGATCGGGCTGGGCGGGGGTAGTCTT
GTCGCGCCGGACGGGCGGAGCGTCGGTCCGCGCAGCGTCGGCTTCCGGCTGATGCAGGAAGCCCGCATCTTCGGTGGCAA
CACGCTCACCGCCAGCGATATCGCGGTCGCTGCCGGACGAGCGCGCTTCGGTGATCCGACGCGCGTGGCCGATCTCTCTC
CTGTGGTCGTCCAACGAGCTCTCACGATCATCGACCAGCGCCTCGCCGAACTTGTCGATAGCCTCAAGACCTCGGCCGGG
CCGGTTCCCGTCATCGTCGTCGGTGGTGGAAGCGTCCTCGTACCGGGCCAACTCGAAGGAGCGAGCGAGGTGATCCGGCC
ACCCTACGCGGCAGTCGCCAACGCGATCGGGGCAGCGATCGCCCAGGTGAGCGGCGAAGTCGACCGGATCGTCTCGCTGG
AGGGGCAGACGCGGGAGAGCGCATTGGCCGCAGCACGAGCGGACGCCTGCCGAGCAGCCATCGCCGCTGGTGCCGATCCA
GCTACCGTGAGCGTGGTGGAGGTCGAAGAAGTACCCATTGCGTATCTGCCCTCGAACGCCGTCCGGATCCGCATCAAAGC
AGTTGGGGATCTCCGAGGAGGCTGA

Upstream 100 bases:

>100_bases
ACGCTCATCAATGCCGGTATGCTCGGCGTGATCGCTCTCCTGGCCGAAGTGATGGCCATGACCTGGTTCGCACCGGTTCG
AGAAACGGGGGCACGACACA

Downstream 100 bases:

>100_bases
GGTGATGTGGGAGTTGGACGAGGAGAAGCTGGAGGCCATCACCATCGGGGCAGGCATCTTAGGTACCGGCGGAGGCGGCA
ATCCCTATTACGGCAAGCTC

Product: hydantoinase

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 514; Mature: 513

Protein sequence:

>514_residues
MARLGIDVGGTNTDAVLLDRSEVLAWAKEPTTPDVSTGILRVVRDVLAQARIAPDEIRAVMLGTTHFTNAVVQRQELARI
AVLRLGLPATASIPPLEDWPDDLRDAVAGFIALLPGGHQFDGREISPLDHSALNQVCERIAELGISSAAVTAVFSPATSA
HEDAVADLLASRVPGLRITRSREIGRLGLLERENAAALNACLVPLAERTIRAFQDALAELGLTAPLYLSQNDGTLMTADF
ATRYPVLTFASGPTNSMRGAAVLSGLRDAIVLDVGGTTTDGGALVNGFPREASFAVTIGGVRTNFRMPDVVSIGLGGGSL
VAPDGRSVGPRSVGFRLMQEARIFGGNTLTASDIAVAAGRARFGDPTRVADLSPVVVQRALTIIDQRLAELVDSLKTSAG
PVPVIVVGGGSVLVPGQLEGASEVIRPPYAAVANAIGAAIAQVSGEVDRIVSLEGQTRESALAAARADACRAAIAAGADP
ATVSVVEVEEVPIAYLPSNAVRIRIKAVGDLRGG

Sequences:

>Translated_514_residues
MARLGIDVGGTNTDAVLLDRSEVLAWAKEPTTPDVSTGILRVVRDVLAQARIAPDEIRAVMLGTTHFTNAVVQRQELARI
AVLRLGLPATASIPPLEDWPDDLRDAVAGFIALLPGGHQFDGREISPLDHSALNQVCERIAELGISSAAVTAVFSPATSA
HEDAVADLLASRVPGLRITRSREIGRLGLLERENAAALNACLVPLAERTIRAFQDALAELGLTAPLYLSQNDGTLMTADF
ATRYPVLTFASGPTNSMRGAAVLSGLRDAIVLDVGGTTTDGGALVNGFPREASFAVTIGGVRTNFRMPDVVSIGLGGGSL
VAPDGRSVGPRSVGFRLMQEARIFGGNTLTASDIAVAAGRARFGDPTRVADLSPVVVQRALTIIDQRLAELVDSLKTSAG
PVPVIVVGGGSVLVPGQLEGASEVIRPPYAAVANAIGAAIAQVSGEVDRIVSLEGQTRESALAAARADACRAAIAAGADP
ATVSVVEVEEVPIAYLPSNAVRIRIKAVGDLRGG
>Mature_513_residues
ARLGIDVGGTNTDAVLLDRSEVLAWAKEPTTPDVSTGILRVVRDVLAQARIAPDEIRAVMLGTTHFTNAVVQRQELARIA
VLRLGLPATASIPPLEDWPDDLRDAVAGFIALLPGGHQFDGREISPLDHSALNQVCERIAELGISSAAVTAVFSPATSAH
EDAVADLLASRVPGLRITRSREIGRLGLLERENAAALNACLVPLAERTIRAFQDALAELGLTAPLYLSQNDGTLMTADFA
TRYPVLTFASGPTNSMRGAAVLSGLRDAIVLDVGGTTTDGGALVNGFPREASFAVTIGGVRTNFRMPDVVSIGLGGGSLV
APDGRSVGPRSVGFRLMQEARIFGGNTLTASDIAVAAGRARFGDPTRVADLSPVVVQRALTIIDQRLAELVDSLKTSAGP
VPVIVVGGGSVLVPGQLEGASEVIRPPYAAVANAIGAAIAQVSGEVDRIVSLEGQTRESALAAARADACRAAIAAGADPA
TVSVVEVEEVPIAYLPSNAVRIRIKAVGDLRGG

Specific function: HyuA and hyuB convert D- and L-substituted hydantoins to corresponding N-carbamyl-amino acids [H]

COG id: COG0145

COG function: function code EQ; N-methylhydantoinase A/acetone carboxylase, beta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the oxoprolinase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008040
- InterPro:   IPR002821 [H]

Pfam domain/function: PF05378 Hydant_A_N; PF01968 Hydantoinase_A [H]

EC number: NA

Molecular weight: Translated: 53212; Mature: 53081

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARLGIDVGGTNTDAVLLDRSEVLAWAKEPTTPDVSTGILRVVRDVLAQARIAPDEIRAV
CCEEEEEECCCCCCEEEEEHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHEEE
MLGTTHFTNAVVQRQELARIAVLRLGLPATASIPPLEDWPDDLRDAVAGFIALLPGGHQF
EECCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCC
DGREISPLDHSALNQVCERIAELGISSAAVTAVFSPATSAHEDAVADLLASRVPGLRITR
CCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHEEECCCCCCHHHHHHHHHHHCCCCCEEEC
SREIGRLGLLERENAAALNACLVPLAERTIRAFQDALAELGLTAPLYLSQNDGTLMTADF
CCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEECC
ATRYPVLTFASGPTNSMRGAAVLSGLRDAIVLDVGGTTTDGGALVNGFPREASFAVTIGG
CCCCCEEEECCCCCCCCHHHHHHHCCCCEEEEECCCCCCCCCCEECCCCCCCEEEEEECC
VRTNFRMPDVVSIGLGGGSLVAPDGRSVGPRSVGFRLMQEARIFGGNTLTASDIAVAAGR
EEECCCCCCEEEEECCCCCEECCCCCCCCCHHHHHHHHHHHHHCCCCEEEHHHHHHCCCC
ARFGDPTRVADLSPVVVQRALTIIDQRLAELVDSLKTSAGPVPVIVVGGGSVLVPGQLEG
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEECCCCCC
ASEVIRPPYAAVANAIGAAIAQVSGEVDRIVSLEGQTRESALAAARADACRAAIAAGADP
CHHHHCCCHHHHHHHHHHHHHHHCCCHHHEEECCCCCHHHHHHHHHHHHHHHHHHCCCCC
ATVSVVEVEEVPIAYLPSNAVRIRIKAVGDLRGG
CEEEEEEECCCCEEEECCCEEEEEEEEECCCCCC
>Mature Secondary Structure 
ARLGIDVGGTNTDAVLLDRSEVLAWAKEPTTPDVSTGILRVVRDVLAQARIAPDEIRAV
CEEEEEECCCCCCEEEEEHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHEEE
MLGTTHFTNAVVQRQELARIAVLRLGLPATASIPPLEDWPDDLRDAVAGFIALLPGGHQF
EECCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCC
DGREISPLDHSALNQVCERIAELGISSAAVTAVFSPATSAHEDAVADLLASRVPGLRITR
CCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHEEECCCCCCHHHHHHHHHHHCCCCCEEEC
SREIGRLGLLERENAAALNACLVPLAERTIRAFQDALAELGLTAPLYLSQNDGTLMTADF
CCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEECC
ATRYPVLTFASGPTNSMRGAAVLSGLRDAIVLDVGGTTTDGGALVNGFPREASFAVTIGG
CCCCCEEEECCCCCCCCHHHHHHHCCCCEEEEECCCCCCCCCCEECCCCCCCEEEEEECC
VRTNFRMPDVVSIGLGGGSLVAPDGRSVGPRSVGFRLMQEARIFGGNTLTASDIAVAAGR
EEECCCCCCEEEEECCCCCEECCCCCCCCCHHHHHHHHHHHHHCCCCEEEHHHHHHCCCC
ARFGDPTRVADLSPVVVQRALTIIDQRLAELVDSLKTSAGPVPVIVVGGGSVLVPGQLEG
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEECCCCCC
ASEVIRPPYAAVANAIGAAIAQVSGEVDRIVSLEGQTRESALAAARADACRAAIAAGADP
CHHHHCCCHHHHHHHHHHHHHHHCCCHHHEEECCCCCHHHHHHHHHHHHHHHHHHCCCCC
ATVSVVEVEEVPIAYLPSNAVRIRIKAVGDLRGG
CEEEEEEECCCCEEEECCCEEEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1732229 [H]