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The map label for this gene is appC [H]

Identifier: 221633235

GI number: 221633235

Start: 1237235

End: 1238197

Strand: Reverse

Name: appC [H]

Synonym: trd_1253

Alternate gene names: 221633235

Gene position: 1238197-1237235 (Counterclockwise)

Preceding gene: 221633236

Following gene: 221633234

Centisome position: 61.82

GC content: 61.06

Gene sequence:

>963_bases
ATGTCCGAAGCGACCGAGCAGCGCAGGCTGGAGACCGCGGCACGCACGGTCGGGCCACCCGTGGTACTGCCGACACGCAA
GCCGCGGTCGCTCTGGAGCGATGCGTGGAGGCAGTTTCGGCACCACCGGCTCGCGGTGGCGGGAACCATCGTCTTGGTGT
TCATGATCCTGGCCACGATCATCGGTCCGTTTCTCTGGCCGATTCCCTGGAACACGTTCGATATGGCGGAAGCCCTGCAA
GGACCGTCACTCCGGCACCCCTTCGGCACGACGGATCTCGGCCATGACATCTTCGCGCGTATTCTTTGGGGTGGACGGAT
CTCGATCGCGGTGGGTGTCGTCGCCATGTTGGTTGCGGTGACGCTGGGAACGCTCATCGGTGCGGTCGCAGGATATTTCG
GAGGAATCCTGGATTCGTTCTTGATGCGGATGACCGATATGTTCATCTCGATCCCGAGCCTCCCGTTGCTTCTCCTGATC
ACCTACCTTTTCCAGGATCGGATGAAAGCGCTCTTTGGGGTCGAGCTCGGTATGTTTTTGCTGATCGTCCTCGTGATCGG
CGGGTTGAACTGGATGCCGGTGGCGCGCCTGGTGCGTGCTTCGTTCCTGTCGCTCAAGCAGAAGGAGTTCGTGGAGGCGG
CACACTGCATCGGCGTGAGTACCAGCGGGATCATCTTCCGCCATATCTTGCCGAACACGCTGAGCCCGGTGATCGTGGCG
GCGACACTCGGCGTCGCACAAGCGATCATCACCGAGTCAGCCCTGTCCTTCCTCGGACTCGGTTTCCCGCCCGACATCCC
GACGTGGGGCCGCATGCTGTACGATGGAATCAATTGGATCGAGTTCGCACCATGGATGGTTCTCTTCCCCGGTGCGGCGA
TCTTCCTAACCGTGCTGAGCATCAACTACGTCGGTGATGGACTCCGGGACGCACTCGATCCACGGCGCATGTTCGCGATC
TGA

Upstream 100 bases:

>100_bases
GCGCTGGTCGTCTTGTTCAACCTGATCGCCGATATTTTGTACGGGGTACTCGATCCGCGGATCAAGTACGAGTGAGTGGC
CGCGACGGGGGGGTAACGCG

Downstream 100 bases:

>100_bases
GGGGTAGCATGACGACGCGTGGCCGGGCGAGCGCACGGGAGAAAACGGTGGGAGCGCTCGCTCAGATGACTCTCGTTTGT
GACCGTTGTAGTGCGAGGTT

Product: oligopeptide transport system permease OppC

Products: ADP; phosphate; oligopeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 320; Mature: 319

Protein sequence:

>320_residues
MSEATEQRRLETAARTVGPPVVLPTRKPRSLWSDAWRQFRHHRLAVAGTIVLVFMILATIIGPFLWPIPWNTFDMAEALQ
GPSLRHPFGTTDLGHDIFARILWGGRISIAVGVVAMLVAVTLGTLIGAVAGYFGGILDSFLMRMTDMFISIPSLPLLLLI
TYLFQDRMKALFGVELGMFLLIVLVIGGLNWMPVARLVRASFLSLKQKEFVEAAHCIGVSTSGIIFRHILPNTLSPVIVA
ATLGVAQAIITESALSFLGLGFPPDIPTWGRMLYDGINWIEFAPWMVLFPGAAIFLTVLSINYVGDGLRDALDPRRMFAI

Sequences:

>Translated_320_residues
MSEATEQRRLETAARTVGPPVVLPTRKPRSLWSDAWRQFRHHRLAVAGTIVLVFMILATIIGPFLWPIPWNTFDMAEALQ
GPSLRHPFGTTDLGHDIFARILWGGRISIAVGVVAMLVAVTLGTLIGAVAGYFGGILDSFLMRMTDMFISIPSLPLLLLI
TYLFQDRMKALFGVELGMFLLIVLVIGGLNWMPVARLVRASFLSLKQKEFVEAAHCIGVSTSGIIFRHILPNTLSPVIVA
ATLGVAQAIITESALSFLGLGFPPDIPTWGRMLYDGINWIEFAPWMVLFPGAAIFLTVLSINYVGDGLRDALDPRRMFAI
>Mature_319_residues
SEATEQRRLETAARTVGPPVVLPTRKPRSLWSDAWRQFRHHRLAVAGTIVLVFMILATIIGPFLWPIPWNTFDMAEALQG
PSLRHPFGTTDLGHDIFARILWGGRISIAVGVVAMLVAVTLGTLIGAVAGYFGGILDSFLMRMTDMFISIPSLPLLLLIT
YLFQDRMKALFGVELGMFLLIVLVIGGLNWMPVARLVRASFLSLKQKEFVEAAHCIGVSTSGIIFRHILPNTLSPVIVAA
TLGVAQAIITESALSFLGLGFPPDIPTWGRMLYDGINWIEFAPWMVLFPGAAIFLTVLSINYVGDGLRDALDPRRMFAI

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787498, Length=292, Percent_Identity=45.8904109589041, Blast_Score=211, Evalue=4e-56,
Organism=Escherichia coli, GI1787054, Length=298, Percent_Identity=38.9261744966443, Blast_Score=202, Evalue=2e-53,
Organism=Escherichia coli, GI1787760, Length=295, Percent_Identity=34.9152542372881, Blast_Score=162, Evalue=4e-41,
Organism=Escherichia coli, GI1789964, Length=323, Percent_Identity=34.0557275541796, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI1788505, Length=237, Percent_Identity=34.1772151898734, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1789889, Length=252, Percent_Identity=32.9365079365079, Blast_Score=127, Evalue=7e-31,
Organism=Escherichia coli, GI1787549, Length=301, Percent_Identity=29.5681063122924, Blast_Score=117, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 35200; Mature: 35069

Theoretical pI: Translated: 9.58; Mature: 9.58

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEATEQRRLETAARTVGPPVVLPTRKPRSLWSDAWRQFRHHRLAVAGTIVLVFMILATI
CCCHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGPFLWPIPWNTFDMAEALQGPSLRHPFGTTDLGHDIFARILWGGRISIAVGVVAMLVAV
HHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHH
TLGTLIGAVAGYFGGILDSFLMRMTDMFISIPSLPLLLLITYLFQDRMKALFGVELGMFL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIVLVIGGLNWMPVARLVRASFLSLKQKEFVEAAHCIGVSTSGIIFRHILPNTLSPVIVA
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHH
ATLGVAQAIITESALSFLGLGFPPDIPTWGRMLYDGINWIEFAPWMVLFPGAAIFLTVLS
HHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCHHHHCCHHHHHCCHHHHHHHHH
INYVGDGLRDALDPRRMFAI
HHHHCCHHHHHCCCHHHHCC
>Mature Secondary Structure 
SEATEQRRLETAARTVGPPVVLPTRKPRSLWSDAWRQFRHHRLAVAGTIVLVFMILATI
CCHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH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HHHHCCHHHHHCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; oligopeptides [Periplasm]; H2O [C]

Specific reaction: ATP + oligopeptides [Periplasm] + H2O = ADP + phosphate + oligopeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]