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The map label for this gene is ideR [H]

Identifier: 221633178

GI number: 221633178

Start: 1183641

End: 1184357

Strand: Reverse

Name: ideR [H]

Synonym: trd_1195

Alternate gene names: 221633178

Gene position: 1184357-1183641 (Counterclockwise)

Preceding gene: 221633181

Following gene: 221633177

Centisome position: 59.13

GC content: 62.48

Gene sequence:

>717_bases
GTGAGACAGTCGAGGCGCGCGACTGGGCGAGTACCGATCACGCAGGCGATGGAGGATTATCTGAAAGTCATCTTCGCGCT
CGAGCGCGACGAGGGACGGGTTACGACCCAAGCGATCGCCGAGCGTTTGCGGGTGCAGAGCCCCTCGGTGACGAACATGT
TGAAGCGGATGGCTGCACTTGATCTCGTCGATCACCAACCCTATCGGGGTGTGCGACTGACGGACCGCGGGAGAAGCGTT
GCGCTCGAAGTGATCCGGCATCATCGCTTATTGGAGCGGTTTCTCGCCGAGGTTTTGGAGTATCCGTGGGATGCTCTGCA
CGAAGAGGCGGATCGCCTCGAGCACGGACTTTCCGAGGAACTGGAGTCCTGGATCGACGCACGACTCGGCTTCCCGACCG
AAGATCCGCACGGACATCCCATCCCGCGCAGCGATGGCTCGCTCCCCGAACGACCCTGTCAGCGGTTGCACGATGTCCTG
CCGGGGCAGCAGGTGGAAGTTCTCCATGTTGCCGATCACGATCGCGCACAGCTCCGCTATCTGGCAGAACTGGGTATTCG
CCCGGGCACTCGCCTAGAGGTACTCGAGCGCTTACCGTTCGAGGGGCCACTGCGGGTCCGGATCGGTGATCGCGAGCAGT
ACGTCGGGGAACGATTGGCACGCGGAATCTACGTGACGGCAGCATCGACGGGGGGCAAGGAGCAAGCGACGCGGTAA

Upstream 100 bases:

>100_bases
CTCCTCGCACTGTCTCACCCTTCGAACAGGTGTTCCACGTATACTTGGCGCAACAGCGAGCCCCTCGTCTCGGGGCCAGC
AGGTCGCAGGGAGTGTACCA

Downstream 100 bases:

>100_bases
ATCGTGCGTTTGCCCGCACGGAAGCGAGCCCTCGATTGCCGGCCGATGAATCGTTCGCAGTCAACCGGGTTCGGGTAGTC
CGTCCGATGGGAGAGGCGAA

Product: transcriptional repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 238; Mature: 238

Protein sequence:

>238_residues
MRQSRRATGRVPITQAMEDYLKVIFALERDEGRVTTQAIAERLRVQSPSVTNMLKRMAALDLVDHQPYRGVRLTDRGRSV
ALEVIRHHRLLERFLAEVLEYPWDALHEEADRLEHGLSEELESWIDARLGFPTEDPHGHPIPRSDGSLPERPCQRLHDVL
PGQQVEVLHVADHDRAQLRYLAELGIRPGTRLEVLERLPFEGPLRVRIGDREQYVGERLARGIYVTAASTGGKEQATR

Sequences:

>Translated_238_residues
MRQSRRATGRVPITQAMEDYLKVIFALERDEGRVTTQAIAERLRVQSPSVTNMLKRMAALDLVDHQPYRGVRLTDRGRSV
ALEVIRHHRLLERFLAEVLEYPWDALHEEADRLEHGLSEELESWIDARLGFPTEDPHGHPIPRSDGSLPERPCQRLHDVL
PGQQVEVLHVADHDRAQLRYLAELGIRPGTRLEVLERLPFEGPLRVRIGDREQYVGERLARGIYVTAASTGGKEQATR
>Mature_238_residues
MRQSRRATGRVPITQAMEDYLKVIFALERDEGRVTTQAIAERLRVQSPSVTNMLKRMAALDLVDHQPYRGVRLTDRGRSV
ALEVIRHHRLLERFLAEVLEYPWDALHEEADRLEHGLSEELESWIDARLGFPTEDPHGHPIPRSDGSLPERPCQRLHDVL
PGQQVEVLHVADHDRAQLRYLAELGIRPGTRLEVLERLPFEGPLRVRIGDREQYVGERLARGIYVTAASTGGKEQATR

Specific function: Metal-dependent DNA-binding protein that controls transcription of many genes involved in iron metabolism [H]

COG id: COG1321

COG function: function code K; Mn-dependent transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH dtxR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787038, Length=120, Percent_Identity=36.6666666666667, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007167
- InterPro:   IPR001367
- InterPro:   IPR022689
- InterPro:   IPR022687
- InterPro:   IPR008988
- InterPro:   IPR011991 [H]

Pfam domain/function: PF02742 Fe_dep_repr_C; PF01325 Fe_dep_repress; PF04023 FeoA [H]

EC number: NA

Molecular weight: Translated: 27234; Mature: 27234

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: PS50944 HTH_DTXR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQSRRATGRVPITQAMEDYLKVIFALERDEGRVTTQAIAERLRVQSPSVTNMLKRMAAL
CCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHH
DLVDHQPYRGVRLTDRGRSVALEVIRHHRLLERFLAEVLEYPWDALHEEADRLEHGLSEE
HHHCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
LESWIDARLGFPTEDPHGHPIPRSDGSLPERPCQRLHDVLPGQQVEVLHVADHDRAQLRY
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCHHHHHH
LAELGIRPGTRLEVLERLPFEGPLRVRIGDREQYVGERLARGIYVTAASTGGKEQATR
HHHHCCCCCHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHCCEEEEEECCCCCCCCCC
>Mature Secondary Structure
MRQSRRATGRVPITQAMEDYLKVIFALERDEGRVTTQAIAERLRVQSPSVTNMLKRMAAL
CCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHH
DLVDHQPYRGVRLTDRGRSVALEVIRHHRLLERFLAEVLEYPWDALHEEADRLEHGLSEE
HHHCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
LESWIDARLGFPTEDPHGHPIPRSDGSLPERPCQRLHDVLPGQQVEVLHVADHDRAQLRY
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCHHHHHH
LAELGIRPGTRLEVLERLPFEGPLRVRIGDREQYVGERLARGIYVTAASTGGKEQATR
HHHHCCCCCHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHCCEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]