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The map label for this gene is otsB [H]

Identifier: 221632885

GI number: 221632885

Start: 867288

End: 868079

Strand: Reverse

Name: otsB [H]

Synonym: trd_0884

Alternate gene names: 221632885

Gene position: 868079-867288 (Counterclockwise)

Preceding gene: 221632887

Following gene: 221632882

Centisome position: 43.34

GC content: 63.38

Gene sequence:

>792_bases
TTGGAATCGATCGTTGGCGCGATGCTCGCCGTACTCGACGAGACAGGAGCGGGGATCATCACCGATTTCGATGGGACGCT
GAGTCCGATCGTCGCTGATCCTGAGAAGGCAACCGTCCATCCAGTCGCCCGCCGAGCCTTGCTCCGTCTCGTCAAGACCG
TTTCGCTCGTCGCTATCGTCTCGGGTCGGCGCGCCTCCGACGTCGCTGGTCGGCTGGCAGTTCCAGGACTGGTGATCGTG
GGCAACCACGGACTCGAATGGTTGGTCGGAGGTCACGTGGAGGTCGCTCCCGAGGCCGAACCCTGGCTCGGCGCGGTACG
AGCGGCTGCGGCCGAAGTCCAGCGACTTTGTCCGGACGTGCTGGTCGAGGACAAGGCGCTCACCGTCACGATTCATCTGC
GGCGACTGCGGAATGTCTCGCGCCGGCGGGCAGTGGAGACCGTCGTGCGGCGGGTCGCAGGGGAGTACGGGTTGTCGATC
CGTCAGGGACGCGAGGTGCTGGAGTTGCGACCACCTGTCCCGATCGACAAGGGTACGGCTGTCGATCAGCTCGTTACCCG
TTACCAGCTCCGGGCTGTCGTTTTTGCTGGGGACGATGTCACTGATCTCGATGCCATGCGCTTGCTCGTCGTTCGACGAG
CTAGCGGACAGGTTCATGCTCTCTTGATCGGTGTCTGGAGCTCGGAAGCACCGCCAGAACTGAAGCAGCTCGCCGATCTG
CTGGTACCGGGCGTGGATGCATTCGCCGCTGTGTTGGACGAGCTCGCTCATCGACTCGCTGAGCTTCAGTAG

Upstream 100 bases:

>100_bases
TGGGCACCAGTTGCCCCCTTCCCTCCGGCCGCAGTATACGACTCGTCAGGACTGATCTGGGCGGGGTGCACTGCTGTCGG
GTGGCAGGGGGAGGAAGACG

Downstream 100 bases:

>100_bases
GTATCGAGCGGCCAGGCGGGGCGCTTCACCGATCGATATGAGAAGAAGGCGAGGTCCGGTGTGGCAATGCCTGGAGTGAC
TGCCTGCAGCACTTGCGCCG

Product: trehalose-phosphatase

Products: NA

Alternate protein names: TPP; Trehalose-6-phosphate phosphatase [H]

Number of amino acids: Translated: 263; Mature: 263

Protein sequence:

>263_residues
MESIVGAMLAVLDETGAGIITDFDGTLSPIVADPEKATVHPVARRALLRLVKTVSLVAIVSGRRASDVAGRLAVPGLVIV
GNHGLEWLVGGHVEVAPEAEPWLGAVRAAAAEVQRLCPDVLVEDKALTVTIHLRRLRNVSRRRAVETVVRRVAGEYGLSI
RQGREVLELRPPVPIDKGTAVDQLVTRYQLRAVVFAGDDVTDLDAMRLLVVRRASGQVHALLIGVWSSEAPPELKQLADL
LVPGVDAFAAVLDELAHRLAELQ

Sequences:

>Translated_263_residues
MESIVGAMLAVLDETGAGIITDFDGTLSPIVADPEKATVHPVARRALLRLVKTVSLVAIVSGRRASDVAGRLAVPGLVIV
GNHGLEWLVGGHVEVAPEAEPWLGAVRAAAAEVQRLCPDVLVEDKALTVTIHLRRLRNVSRRRAVETVVRRVAGEYGLSI
RQGREVLELRPPVPIDKGTAVDQLVTRYQLRAVVFAGDDVTDLDAMRLLVVRRASGQVHALLIGVWSSEAPPELKQLADL
LVPGVDAFAAVLDELAHRLAELQ
>Mature_263_residues
MESIVGAMLAVLDETGAGIITDFDGTLSPIVADPEKATVHPVARRALLRLVKTVSLVAIVSGRRASDVAGRLAVPGLVIV
GNHGLEWLVGGHVEVAPEAEPWLGAVRAAAAEVQRLCPDVLVEDKALTVTIHLRRLRNVSRRRAVETVVRRVAGEYGLSI
RQGREVLELRPPVPIDKGTAVDQLVTRYQLRAVVFAGDDVTDLDAMRLLVVRRASGQVHALLIGVWSSEAPPELKQLADL
LVPGVDAFAAVLDELAHRLAELQ

Specific function: Removes the phosphate from trehalose 6-phosphate to produce free trehalose [H]

COG id: COG1877

COG function: function code G; Trehalose-6-phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trehalose phosphatase family [H]

Homologues:

Organism=Drosophila melanogaster, GI221473368, Length=216, Percent_Identity=31.9444444444444, Blast_Score=93, Evalue=1e-19,
Organism=Drosophila melanogaster, GI20129307, Length=216, Percent_Identity=31.9444444444444, Blast_Score=93, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24582490, Length=216, Percent_Identity=31.9444444444444, Blast_Score=93, Evalue=1e-19,
Organism=Drosophila melanogaster, GI19920676, Length=203, Percent_Identity=32.512315270936, Blast_Score=87, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR006379
- InterPro:   IPR003337 [H]

Pfam domain/function: PF02358 Trehalose_PPase [H]

EC number: =3.1.3.12 [H]

Molecular weight: Translated: 28232; Mature: 28232

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESIVGAMLAVLDETGAGIITDFDGTLSPIVADPEKATVHPVARRALLRLVKTVSLVAIV
CHHHHHHHHHHHHCCCCCEEEECCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHH
SGRRASDVAGRLAVPGLVIVGNHGLEWLVGGHVEVAPEAEPWLGAVRAAAAEVQRLCPDV
CCCCHHHHHCHHCCCCEEEECCCCCEEEECCCEEECCCCCHHHHHHHHHHHHHHHHCHHH
LVEDKALTVTIHLRRLRNVSRRRAVETVVRRVAGEYGLSIRQGREVLELRPPVPIDKGTA
HCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCHHEECCCCCCCCCCCH
VDQLVTRYQLRAVVFAGDDVTDLDAMRLLVVRRASGQVHALLIGVWSSEAPPELKQLADL
HHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHH
LVPGVDAFAAVLDELAHRLAELQ
HCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MESIVGAMLAVLDETGAGIITDFDGTLSPIVADPEKATVHPVARRALLRLVKTVSLVAIV
CHHHHHHHHHHHHCCCCCEEEECCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHH
SGRRASDVAGRLAVPGLVIVGNHGLEWLVGGHVEVAPEAEPWLGAVRAAAAEVQRLCPDV
CCCCHHHHHCHHCCCCEEEECCCCCEEEECCCEEECCCCCHHHHHHHHHHHHHHHHCHHH
LVEDKALTVTIHLRRLRNVSRRRAVETVVRRVAGEYGLSIRQGREVLELRPPVPIDKGTA
HCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCHHEECCCCCCCCCCCH
VDQLVTRYQLRAVVFAGDDVTDLDAMRLLVVRRASGQVHALLIGVWSSEAPPELKQLADL
HHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHH
LVPGVDAFAAVLDELAHRLAELQ
HCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8446027; 11234002 [H]