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The map label for this gene is accD [H]

Identifier: 221632882

GI number: 221632882

Start: 863915

End: 865540

Strand: Reverse

Name: accD [H]

Synonym: trd_0882

Alternate gene names: 221632882

Gene position: 865540-863915 (Counterclockwise)

Preceding gene: 221632885

Following gene: 221632881

Centisome position: 43.21

GC content: 61.13

Gene sequence:

>1626_bases
GTGGATCCTGAGAGTTTCGAGGAATTCAACCGGCATCTCGTATCGGTCGATCCGCTGGTCTTTTCCGATCGTTTGCCGTA
TCGAAAGCGGATTCTCCAAGCCAGGGAAGAAACCGGACTGCGTGAAGCGGTCGTGACCGGTATCGGGCGCATTCGTGGTC
ACGAAGTCGTGCTGGCTGTCCTGGACTTCCGTTTCTTGGGCGGAAGCATGGGATCGGTCGTGGGCGAAAAGGTCACGCTG
GCGTTCGAGCGGGCAGCTGAGCGACATCTGCCGATCGTCACGGTTTCTGCCTCCGGTGGAGCACGGATGCAAGAAGGCAT
CCTCAGTCTCGTTCAGATGGCAAAGACCACCGCGGCAGCCAAGCGTGCACACGACTCCAACGTTCCCTATATATCTGTAC
TGACTCATCCGACGACAGGCGGAATCTATGCCTCCTTCGCCAACCAGGGCGACATCATTCTCGCGGAACCGGGAGCATTG
ATCGGCTTCGCTGGGCCGCGCGTCGTGAAGGAGACCGCCGGACATGAGCCACTGCGTTCGCACTCGGCTGAATTCCTTTG
GGAGCACGGCTTCGTCGACCAAGTTGTCGATCGGCGTCGTTTGCGTGACACGCTCGCCTTGATTCTCAGGCTCGTTTCCG
CTCATGGGACGAGCGGAGGCCGATCGGTTTTGCGTCGTAGCCATCCGATCGACGGGTCGAGGCGACGGGCGTGGGACATC
GTCGAGTTGGCGCGTCATCCGGAGCGTCCGACGACGCTCGACTTGATCCGCCGGATCAGCCCACAATTCATCGAACTGCA
CGGTGACCGCCTCTTCGGTGACGATCCTGCTGTCGTTGGTGGGATCGGCGAGATCGCCGGACGCGGTGTTATCATCATCG
GACACGAACGTGGACACGGCGATCCGAGGAGGCGTAACGGTCAGGCATTGCCGGAGGGGTACCGCAAAGCGTTGCGGCTG
ATGGATTTGGCAGCTCGTTTGCGCCTGCCGGTGATTACCTTGATCGATACGCCGGGTGTCTATCTCGGCGAAGGGGCGGA
GGAACGAGGAATCGCGTCGGCGCTGAGCCAATGTATCGCGGCGATGAGCGTTTTACCGGTGCCCACGGTTGCGGTGATCA
TCGGTGAAGGGGGGAGTGGTGGTGCGCTCGCCCTCGCGGTTGCGGACCGCGTTCTCATGCTGGAGAACGCGATCTACAGC
GTCATTTCACCGGAGGGAGCAGCTGCGATTCTCTATCGCGATGCGTCGCGGGCACCGGAGGTGGCTGAATCGTTGAAGAT
CACCGCACCGGATCTCCTGCGACTCGACGTGATCGATGGGATCGTGCCTGAACCGGAAGGTGGGGCGCACCGCGATCCGG
ATTACGCCGCTGTTCTGGTCCTGGACGCCATCGTCGAGGCGCTGAACGAGGTCGTCGACATTCCGCCCGACAAGCTGGTT
CGCGAGCGGTACCGGAAGTTCCGGCGCATGGGCCAGACCAATACCTACATTCGCGAGCTGGTGGCACAAGAGGTGGCTGA
GCTGAGCGCGACGATCGGGCGAACACTGGGAAGCTTGCGCGACCGCTTTCCTTTCAGCAAAGACGAGGAAGTGGTGGAAG
CATCGCCGACGGTTCGCCAAGAATGA

Upstream 100 bases:

>100_bases
AACGGATTTGAATGCAGATGATGCCTACCGGCGCTACCGCGTTTGCGGACAGTGTGGGTACCATTTCACGCTCTCGGCCG
ACGAGCGGATCCGACTGCTC

Downstream 100 bases:

>100_bases
GTCCGAGATGTGGGGCGCTTGCTCGAGATGAGGGCGTACGAGACGCTGTGCGTGATCGTTGACGGCAGATCTTCATTCGT
CTAGACTTCCGATGTCGGTC

Product: putative carboxyltransferase subunit of acetyl-CoA carboxylase

Products: NA

Alternate protein names: ACCase subunits beta/alpha; Acetyl-CoA carboxylase carboxyltransferase subunits beta/alpha [H]

Number of amino acids: Translated: 541; Mature: 541

Protein sequence:

>541_residues
MDPESFEEFNRHLVSVDPLVFSDRLPYRKRILQAREETGLREAVVTGIGRIRGHEVVLAVLDFRFLGGSMGSVVGEKVTL
AFERAAERHLPIVTVSASGGARMQEGILSLVQMAKTTAAAKRAHDSNVPYISVLTHPTTGGIYASFANQGDIILAEPGAL
IGFAGPRVVKETAGHEPLRSHSAEFLWEHGFVDQVVDRRRLRDTLALILRLVSAHGTSGGRSVLRRSHPIDGSRRRAWDI
VELARHPERPTTLDLIRRISPQFIELHGDRLFGDDPAVVGGIGEIAGRGVIIIGHERGHGDPRRRNGQALPEGYRKALRL
MDLAARLRLPVITLIDTPGVYLGEGAEERGIASALSQCIAAMSVLPVPTVAVIIGEGGSGGALALAVADRVLMLENAIYS
VISPEGAAAILYRDASRAPEVAESLKITAPDLLRLDVIDGIVPEPEGGAHRDPDYAAVLVLDAIVEALNEVVDIPPDKLV
RERYRKFRRMGQTNTYIRELVAQEVAELSATIGRTLGSLRDRFPFSKDEEVVEASPTVRQE

Sequences:

>Translated_541_residues
MDPESFEEFNRHLVSVDPLVFSDRLPYRKRILQAREETGLREAVVTGIGRIRGHEVVLAVLDFRFLGGSMGSVVGEKVTL
AFERAAERHLPIVTVSASGGARMQEGILSLVQMAKTTAAAKRAHDSNVPYISVLTHPTTGGIYASFANQGDIILAEPGAL
IGFAGPRVVKETAGHEPLRSHSAEFLWEHGFVDQVVDRRRLRDTLALILRLVSAHGTSGGRSVLRRSHPIDGSRRRAWDI
VELARHPERPTTLDLIRRISPQFIELHGDRLFGDDPAVVGGIGEIAGRGVIIIGHERGHGDPRRRNGQALPEGYRKALRL
MDLAARLRLPVITLIDTPGVYLGEGAEERGIASALSQCIAAMSVLPVPTVAVIIGEGGSGGALALAVADRVLMLENAIYS
VISPEGAAAILYRDASRAPEVAESLKITAPDLLRLDVIDGIVPEPEGGAHRDPDYAAVLVLDAIVEALNEVVDIPPDKLV
RERYRKFRRMGQTNTYIRELVAQEVAELSATIGRTLGSLRDRFPFSKDEEVVEASPTVRQE
>Mature_541_residues
MDPESFEEFNRHLVSVDPLVFSDRLPYRKRILQAREETGLREAVVTGIGRIRGHEVVLAVLDFRFLGGSMGSVVGEKVTL
AFERAAERHLPIVTVSASGGARMQEGILSLVQMAKTTAAAKRAHDSNVPYISVLTHPTTGGIYASFANQGDIILAEPGAL
IGFAGPRVVKETAGHEPLRSHSAEFLWEHGFVDQVVDRRRLRDTLALILRLVSAHGTSGGRSVLRRSHPIDGSRRRAWDI
VELARHPERPTTLDLIRRISPQFIELHGDRLFGDDPAVVGGIGEIAGRGVIIIGHERGHGDPRRRNGQALPEGYRKALRL
MDLAARLRLPVITLIDTPGVYLGEGAEERGIASALSQCIAAMSVLPVPTVAVIIGEGGSGGALALAVADRVLMLENAIYS
VISPEGAAAILYRDASRAPEVAESLKITAPDLLRLDVIDGIVPEPEGGAHRDPDYAAVLVLDAIVEALNEVVDIPPDKLV
RERYRKFRRMGQTNTYIRELVAQEVAELSATIGRTLGSLRDRFPFSKDEEVVEASPTVRQE

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA [H

COG id: COG0825

COG function: function code I; Acetyl-CoA carboxylase alpha subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the AccA family [H]

Homologues:

Organism=Escherichia coli, GI1786382, Length=258, Percent_Identity=50, Blast_Score=251, Evalue=7e-68,
Organism=Escherichia coli, GI1788655, Length=210, Percent_Identity=48.0952380952381, Blast_Score=186, Evalue=3e-48,
Organism=Caenorhabditis elegans, GI25147362, Length=422, Percent_Identity=24.8815165876777, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI25147359, Length=422, Percent_Identity=24.8815165876777, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24586065, Length=399, Percent_Identity=27.3182957393484, Blast_Score=82, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001095
- InterPro:   IPR000438
- InterPro:   IPR011763
- InterPro:   IPR011762 [H]

Pfam domain/function: PF03255 ACCA [H]

EC number: =6.4.1.2 [H]

Molecular weight: Translated: 58819; Mature: 58819

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: PS50980 COA_CT_NTER ; PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDPESFEEFNRHLVSVDPLVFSDRLPYRKRILQAREETGLREAVVTGIGRIRGHEVVLAV
CCCHHHHHHHHHEEECCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHH
LDFRFLGGSMGSVVGEKVTLAFERAAERHLPIVTVSASGGARMQEGILSLVQMAKTTAAA
HHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHH
KRAHDSNVPYISVLTHPTTGGIYASFANQGDIILAEPGALIGFAGPRVVKETAGHEPLRS
HHCCCCCCCEEEEEECCCCCCEEEEECCCCCEEEECCCCEEECCCCHHHHHHCCCCCHHH
HSAEFLWEHGFVDQVVDRRRLRDTLALILRLVSAHGTSGGRSVLRRSHPIDGSRRRAWDI
CCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCHHHHHHH
VELARHPERPTTLDLIRRISPQFIELHGDRLFGDDPAVVGGIGEIAGRGVIIIGHERGHG
HHHHHCCCCCCHHHHHHHCCCHHEEECCCEECCCCCHHCCCHHHHCCCCEEEEECCCCCC
DPRRRNGQALPEGYRKALRLMDLAARLRLPVITLIDTPGVYLGEGAEERGIASALSQCIA
CCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCEECCCCCHHHHHHHHHHHHH
AMSVLPVPTVAVIIGEGGSGGALALAVADRVLMLENAIYSVISPEGAAAILYRDASRAPE
HHHHCCCCEEEEEEECCCCCCEEHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHH
VAESLKITAPDLLRLDVIDGIVPEPEGGAHRDPDYAAVLVLDAIVEALNEVVDIPPDKLV
HHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHH
RERYRKFRRMGQTNTYIRELVAQEVAELSATIGRTLGSLRDRFPFSKDEEVVEASPTVRQ
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCC
E
C
>Mature Secondary Structure
MDPESFEEFNRHLVSVDPLVFSDRLPYRKRILQAREETGLREAVVTGIGRIRGHEVVLAV
CCCHHHHHHHHHEEECCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHH
LDFRFLGGSMGSVVGEKVTLAFERAAERHLPIVTVSASGGARMQEGILSLVQMAKTTAAA
HHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHH
KRAHDSNVPYISVLTHPTTGGIYASFANQGDIILAEPGALIGFAGPRVVKETAGHEPLRS
HHCCCCCCCEEEEEECCCCCCEEEEECCCCCEEEECCCCEEECCCCHHHHHHCCCCCHHH
HSAEFLWEHGFVDQVVDRRRLRDTLALILRLVSAHGTSGGRSVLRRSHPIDGSRRRAWDI
CCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCHHHHHHH
VELARHPERPTTLDLIRRISPQFIELHGDRLFGDDPAVVGGIGEIAGRGVIIIGHERGHG
HHHHHCCCCCCHHHHHHHCCCHHEEECCCEECCCCCHHCCCHHHHCCCCEEEEECCCCCC
DPRRRNGQALPEGYRKALRLMDLAARLRLPVITLIDTPGVYLGEGAEERGIASALSQCIA
CCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCEECCCCCHHHHHHHHHHHHH
AMSVLPVPTVAVIIGEGGSGGALALAVADRVLMLENAIYSVISPEGAAAILYRDASRAPE
HHHHCCCCEEEEEEECCCCCCEEHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHH
VAESLKITAPDLLRLDVIDGIVPEPEGGAHRDPDYAAVLVLDAIVEALNEVVDIPPDKLV
HHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHH
RERYRKFRRMGQTNTYIRELVAQEVAELSATIGRTLGSLRDRFPFSKDEEVVEASPTVRQ
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCC
E
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12552129 [H]