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The map label for this gene is yabD [H]

Identifier: 221632751

GI number: 221632751

Start: 731261

End: 732040

Strand: Reverse

Name: yabD [H]

Synonym: trd_0742

Alternate gene names: 221632751

Gene position: 732040-731261 (Counterclockwise)

Preceding gene: 221632752

Following gene: 221632750

Centisome position: 36.55

GC content: 63.59

Gene sequence:

>780_bases
ATGATTCTGGTCGACACGCATTGCCATCTCGACCTCCCCGACTTCGACAACGATCGGCCACTCGTGATCGAGCGGGCCCG
CGATGCTGGCGTCCAGGGATTCGTCCTCATCGCCTTCTCACCGACCCGTTGGGAAGCCGCACTGACACTCGCCGAAGCGA
CACCTGGCATGGTCGTTGCCCTCGGTATCCACCCGAACGAGGCCGACCGCTATGACAGCCAGGTCGAGCAGCGACTCCGC
CAGCTCGCTCGCCACCCGCTGGTACGAGCCATTGGGGAGATCGGGCTCGATTTCCACTGGAAAACGACCGACGCGAAGAC
GCAGGAACGCGCCTTTCGCCGGCAAATTGCCCTCGCCCGTGAGTTGAACTTGCCGATCGTGTTGCACCAGCGCGAAGCTC
TTCATGAGCTCCTGGCCATTCTGGAGGACGCTGACCCGCCTCACCGGGGCGTGATGCACTGCTTCACTGGGGATCCGGCT
GATGCCGCGCGCTTCCTCGAGCTCGGACTGCACCTCGGAATCGGCGGCATCGTGACCTATCGGAGCGCGCCGGATCTCCG
TCGCGCCGTTCAGATGCTGCCGGCAGATCGTATGCTGCTCGAAACGGACGCACCCTACCTCGCGCCAGTGCCATATCGCG
GTCGCCGCAACGAACCGGCTTTTCTCCGTGCGACCGTGGCGACAATCGCTGAACTCCGCAGGCAGACCGAGGACGAGGTC
GCTCGGGCTACCACCCGAAACGCAGTCGCACTGTTCAGGATTCCTCTCTCGATCGAATGA

Upstream 100 bases:

>100_bases
CCAGCACAACTCCTCGCCTACGAGCTGGCAGTGCGCCGCGGCCTGGATCCGGATAAACCACGGAATCTCGCCAAGAGCGT
GACCGTCAAGTGAGGCGAGA

Downstream 100 bases:

>100_bases
GCGAGGTGCAGACGTATGCCGACACATCGGATCGTTCTCGCAACGGCCAACCCAGGAAAGATCCGCGAACTCCGCTCCCT
GCTCCCGCCGAACGTCGAAG

Product: TatD-related deoxyribonuclease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MILVDTHCHLDLPDFDNDRPLVIERARDAGVQGFVLIAFSPTRWEAALTLAEATPGMVVALGIHPNEADRYDSQVEQRLR
QLARHPLVRAIGEIGLDFHWKTTDAKTQERAFRRQIALARELNLPIVLHQREALHELLAILEDADPPHRGVMHCFTGDPA
DAARFLELGLHLGIGGIVTYRSAPDLRRAVQMLPADRMLLETDAPYLAPVPYRGRRNEPAFLRATVATIAELRRQTEDEV
ARATTRNAVALFRIPLSIE

Sequences:

>Translated_259_residues
MILVDTHCHLDLPDFDNDRPLVIERARDAGVQGFVLIAFSPTRWEAALTLAEATPGMVVALGIHPNEADRYDSQVEQRLR
QLARHPLVRAIGEIGLDFHWKTTDAKTQERAFRRQIALARELNLPIVLHQREALHELLAILEDADPPHRGVMHCFTGDPA
DAARFLELGLHLGIGGIVTYRSAPDLRRAVQMLPADRMLLETDAPYLAPVPYRGRRNEPAFLRATVATIAELRRQTEDEV
ARATTRNAVALFRIPLSIE
>Mature_259_residues
MILVDTHCHLDLPDFDNDRPLVIERARDAGVQGFVLIAFSPTRWEAALTLAEATPGMVVALGIHPNEADRYDSQVEQRLR
QLARHPLVRAIGEIGLDFHWKTTDAKTQERAFRRQIALARELNLPIVLHQREALHELLAILEDADPPHRGVMHCFTGDPA
DAARFLELGLHLGIGGIVTYRSAPDLRRAVQMLPADRMLLETDAPYLAPVPYRGRRNEPAFLRATVATIAELRRQTEDEV
ARATTRNAVALFRIPLSIE

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI110349730, Length=263, Percent_Identity=33.8403041825095, Blast_Score=112, Evalue=4e-25,
Organism=Homo sapiens, GI110349734, Length=263, Percent_Identity=33.8403041825095, Blast_Score=111, Evalue=5e-25,
Organism=Homo sapiens, GI226061853, Length=270, Percent_Identity=32.962962962963, Blast_Score=111, Evalue=6e-25,
Organism=Homo sapiens, GI225903424, Length=249, Percent_Identity=33.3333333333333, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI226061614, Length=255, Percent_Identity=32.5490196078431, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI226061595, Length=227, Percent_Identity=33.0396475770925, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI14042943, Length=261, Percent_Identity=26.0536398467433, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI225903439, Length=236, Percent_Identity=25.8474576271186, Blast_Score=79, Evalue=3e-15,
Organism=Escherichia coli, GI1787342, Length=262, Percent_Identity=38.9312977099237, Blast_Score=174, Evalue=4e-45,
Organism=Escherichia coli, GI87082439, Length=255, Percent_Identity=36.4705882352941, Blast_Score=163, Evalue=1e-41,
Organism=Escherichia coli, GI48994985, Length=258, Percent_Identity=34.4961240310078, Blast_Score=138, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI17559024, Length=280, Percent_Identity=29.2857142857143, Blast_Score=134, Evalue=6e-32,
Organism=Caenorhabditis elegans, GI71980746, Length=265, Percent_Identity=29.4339622641509, Blast_Score=117, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI17543026, Length=184, Percent_Identity=33.695652173913, Blast_Score=91, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI17565396, Length=224, Percent_Identity=32.1428571428571, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24648690, Length=285, Percent_Identity=30.5263157894737, Blast_Score=115, Evalue=2e-26,
Organism=Drosophila melanogaster, GI221330018, Length=285, Percent_Identity=27.3684210526316, Blast_Score=98, Evalue=6e-21,
Organism=Drosophila melanogaster, GI24586117, Length=285, Percent_Identity=27.3684210526316, Blast_Score=98, Evalue=6e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 29086; Mature: 29086

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS01137 TATD_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILVDTHCHLDLPDFDNDRPLVIERARDAGVQGFVLIAFSPTRWEAALTLAEATPGMVVA
CEEEECCCEEECCCCCCCCCEEEEECCCCCCCEEEEEEECCCCCCCEEEEECCCCCEEEE
LGIHPNEADRYDSQVEQRLRQLARHPLVRAIGEIGLDFHWKTTDAKTQERAFRRQIALAR
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHH
ELNLPIVLHQREALHELLAILEDADPPHRGVMHCFTGDPADAARFLELGLHLGIGGIVTY
HCCCCEEEECHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCEEEEE
RSAPDLRRAVQMLPADRMLLETDAPYLAPVPYRGRRNEPAFLRATVATIAELRRQTEDEV
CCCHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
ARATTRNAVALFRIPLSIE
HHHHHCCCEEEEEECEECC
>Mature Secondary Structure
MILVDTHCHLDLPDFDNDRPLVIERARDAGVQGFVLIAFSPTRWEAALTLAEATPGMVVA
CEEEECCCEEECCCCCCCCCEEEEECCCCCCCEEEEEEECCCCCCCEEEEECCCCCEEEE
LGIHPNEADRYDSQVEQRLRQLARHPLVRAIGEIGLDFHWKTTDAKTQERAFRRQIALAR
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHH
ELNLPIVLHQREALHELLAILEDADPPHRGVMHCFTGDPADAARFLELGLHLGIGGIVTY
HCCCCEEEECHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCEEEEE
RSAPDLRRAVQMLPADRMLLETDAPYLAPVPYRGRRNEPAFLRATVATIAELRRQTEDEV
CCCHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
ARATTRNAVALFRIPLSIE
HHHHHCCCEEEEEECEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]