| Definition | Thermomicrobium roseum DSM 5159 chromosome, complete genome. |
|---|---|
| Accession | NC_011959 |
| Length | 2,003,006 |
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The map label for this gene is aceB [H]
Identifier: 221632521
GI number: 221632521
Start: 490918
End: 492486
Strand: Reverse
Name: aceB [H]
Synonym: trd_0495
Alternate gene names: 221632521
Gene position: 492486-490918 (Counterclockwise)
Preceding gene: 221632522
Following gene: 221632519
Centisome position: 24.59
GC content: 61.82
Gene sequence:
>1569_bases ATGGGTGATGTGCGGATCGTGGGACGCATGACTCCGGAGTTCGCCCAGATCCTCACCGAACCAGCCCTCGACTTCGTCGC GAGCCTCCATCGAGAGTTCAACCTTCGCCGCAAGCAGCTGCTCGAACGACGAGCCGAACGCCAACAGGCGATCGATGCCG GCCATTTTCCTGATTTTCTTCCCGAAACTGCTCACATTCGTGAAAGCGAGTGGCGTGTCGCGCCGACTCCCCCTGATCTC GAGGATCGGCGCGTCGAGATTACCGGGCCTGTCGATCGCAAAATGATGATCAACGCCCTCAACTCCGGTGCGCGCGTCTT CATGGCGGACTTCGAGGATGCGCTCTCGCCGACTTGGGATAATGTGGTGCAAGGCCAGATCAATCTCCGCGATGCCGTCC GGCGAACCATCAGCTTCGAAAGCCCGGACGGCAGGGTCTATCGTCTCGCCGACAAGACCGCGACACTCGTCGTCCGACCA CGCGGCTGGCATCTCGTCGAACGGCATGTCCTGGTCGATGGAGAACCGATCTCGGCGAGTCTCTTCGACTTCGGTCTCTA CTTTTTCCACAACGCGCACGAGTTGCTAGCCAGGAACACCGGGCCCTACTTCTACTTGCCCAAACTGGAGAGTCACCTGG AAGCGCGCCTCTGGAACGACGTCTTCAACTTCGCCCAGGATCGCCTCGGCATTCCGCGGGGAACGATTCGGGCGACCGTC CTCATCGAGACGATCCTGGCTGCCTTCGAGATGGACGAAATTCTCTGGGAACTGCGTGATCATGCTGCTGGACTCAATGC TGGGCGATGGGATTACATCTTTAGTGTCATCAAGAAGTTCCGCCGGCACCGGGAGTTCCTCCTGCCCGATCGGGCACAGG TCACAATGACCGTGCCGTTCATGCGTGCGTACACCGAACTCTTGGTGCGGACGTGTCACCGCCGTGGAGCACACGCCATC GGCGGAATGGCTGCCTTCATCCCCAGCCGGCGCGATCCGCAAGTCAACGAGATCGCCTTGGCGAAGGTTCGCGAGGACAA GGAACGGGAAGCCAAGGACGGCTTCGACGGGACGTGGGTCGCGCACCCTGACCTCGTCCCCGTCGCGCTCGAAGTTTTCG ATCGCGTCCTGGGCGAGCAACCCCACCAGAAGCATCGCCTCCGCGAGGACGTGCAGGTGACAGCACGCGACTTGCTGGAC GTGCGCGTGCCAGGAGGACGGATCACCGAGGGAGGACTCCGGAACAACGTCAGTGTCGCGCTGCAGTACCTGGACAGCTG GCTGCGTGGCCAAGGCGCCGCGGCCATCTTCAACCTGATGGAGGATACGGCGACTGCCGAGATCTCGCGCGCGCAGCTCT GGCAGTGGCGCTTCCATCGCGCCGAACTCGACGATGGTCGGCCAGTCACGGCCGAGTTGTACGTCCAGATCCGCGACGAG GAACTCACCAAGCTCGGCGGAGAGGTAGCCGGTCGGCTTCGAGAGGCGCGCGAGATCCTCGATCGTCTGGTGCTCGACGA CGAGTTCACCGAGTTTCTCACCTACCTGGCGTACGAGTACATCGACTGA
Upstream 100 bases:
>100_bases CCTGCCGGGATGCAGGGTTTCCGAACTCCGCATCCCGGCTTTTCTTCGTTACACTAGGGGTGACGCTGTGGTGCCATCAC CGGGTGAGGGAGGTATTGTC
Downstream 100 bases:
>100_bases ACGGCAGTTATCCGAAGCCAAGAGAGTCCGAGCGCGAAGGAGCTCGTTGCACGAGCTCCCTCGCGCTCGGACGGTGCCCC AATGTCAGGAGCTGCCCAGG
Product: malate synthase
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 522; Mature: 521
Protein sequence:
>522_residues MGDVRIVGRMTPEFAQILTEPALDFVASLHREFNLRRKQLLERRAERQQAIDAGHFPDFLPETAHIRESEWRVAPTPPDL EDRRVEITGPVDRKMMINALNSGARVFMADFEDALSPTWDNVVQGQINLRDAVRRTISFESPDGRVYRLADKTATLVVRP RGWHLVERHVLVDGEPISASLFDFGLYFFHNAHELLARNTGPYFYLPKLESHLEARLWNDVFNFAQDRLGIPRGTIRATV LIETILAAFEMDEILWELRDHAAGLNAGRWDYIFSVIKKFRRHREFLLPDRAQVTMTVPFMRAYTELLVRTCHRRGAHAI GGMAAFIPSRRDPQVNEIALAKVREDKEREAKDGFDGTWVAHPDLVPVALEVFDRVLGEQPHQKHRLREDVQVTARDLLD VRVPGGRITEGGLRNNVSVALQYLDSWLRGQGAAAIFNLMEDTATAEISRAQLWQWRFHRAELDDGRPVTAELYVQIRDE ELTKLGGEVAGRLREAREILDRLVLDDEFTEFLTYLAYEYID
Sequences:
>Translated_522_residues MGDVRIVGRMTPEFAQILTEPALDFVASLHREFNLRRKQLLERRAERQQAIDAGHFPDFLPETAHIRESEWRVAPTPPDL EDRRVEITGPVDRKMMINALNSGARVFMADFEDALSPTWDNVVQGQINLRDAVRRTISFESPDGRVYRLADKTATLVVRP RGWHLVERHVLVDGEPISASLFDFGLYFFHNAHELLARNTGPYFYLPKLESHLEARLWNDVFNFAQDRLGIPRGTIRATV LIETILAAFEMDEILWELRDHAAGLNAGRWDYIFSVIKKFRRHREFLLPDRAQVTMTVPFMRAYTELLVRTCHRRGAHAI GGMAAFIPSRRDPQVNEIALAKVREDKEREAKDGFDGTWVAHPDLVPVALEVFDRVLGEQPHQKHRLREDVQVTARDLLD VRVPGGRITEGGLRNNVSVALQYLDSWLRGQGAAAIFNLMEDTATAEISRAQLWQWRFHRAELDDGRPVTAELYVQIRDE ELTKLGGEVAGRLREAREILDRLVLDDEFTEFLTYLAYEYID >Mature_521_residues GDVRIVGRMTPEFAQILTEPALDFVASLHREFNLRRKQLLERRAERQQAIDAGHFPDFLPETAHIRESEWRVAPTPPDLE DRRVEITGPVDRKMMINALNSGARVFMADFEDALSPTWDNVVQGQINLRDAVRRTISFESPDGRVYRLADKTATLVVRPR GWHLVERHVLVDGEPISASLFDFGLYFFHNAHELLARNTGPYFYLPKLESHLEARLWNDVFNFAQDRLGIPRGTIRATVL IETILAAFEMDEILWELRDHAAGLNAGRWDYIFSVIKKFRRHREFLLPDRAQVTMTVPFMRAYTELLVRTCHRRGAHAIG GMAAFIPSRRDPQVNEIALAKVREDKEREAKDGFDGTWVAHPDLVPVALEVFDRVLGEQPHQKHRLREDVQVTARDLLDV RVPGGRITEGGLRNNVSVALQYLDSWLRGQGAAAIFNLMEDTATAEISRAQLWQWRFHRAELDDGRPVTAELYVQIRDEE LTKLGGEVAGRLREAREILDRLVLDDEFTEFLTYLAYEYID
Specific function: Glyoxylate bypass; second step. [C]
COG id: COG2225
COG function: function code C; Malate synthase
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the malate synthase family [H]
Homologues:
Organism=Escherichia coli, GI1790444, Length=511, Percent_Identity=51.2720156555773, Blast_Score=537, Evalue=1e-154, Organism=Caenorhabditis elegans, GI17561814, Length=510, Percent_Identity=54.5098039215686, Blast_Score=549, Evalue=1e-156, Organism=Caenorhabditis elegans, GI71982926, Length=409, Percent_Identity=55.9902200488998, Blast_Score=456, Evalue=1e-129, Organism=Saccharomyces cerevisiae, GI6324212, Length=516, Percent_Identity=53.4883720930233, Blast_Score=546, Evalue=1e-156, Organism=Saccharomyces cerevisiae, GI6322222, Length=529, Percent_Identity=51.7958412098299, Blast_Score=536, Evalue=1e-153,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011076 - InterPro: IPR006252 - InterPro: IPR001465 - InterPro: IPR019830 [H]
Pfam domain/function: PF01274 Malate_synthase [H]
EC number: =2.3.3.9 [H]
Molecular weight: Translated: 60077; Mature: 59946
Theoretical pI: Translated: 6.00; Mature: 6.00
Prosite motif: PS00510 MALATE_SYNTHASE
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.2 %Cys (Translated Protein) 1.9 %Met (Translated Protein) 2.1 %Cys+Met (Translated Protein) 0.2 %Cys (Mature Protein) 1.7 %Met (Mature Protein) 1.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MGDVRIVGRMTPEFAQILTEPALDFVASLHREFNLRRKQLLERRAERQQAIDAGHFPDFL CCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC PETAHIRESEWRVAPTPPDLEDRRVEITGPVDRKMMINALNSGARVFMADFEDALSPTWD CCCCCCCCCCCEECCCCCCCCCCEEEEECCCCHHHHHHHHCCCCEEEEECHHHHCCCCHH NVVQGQINLRDAVRRTISFESPDGRVYRLADKTATLVVRPRGWHLVERHVLVDGEPISAS HHHCCCCCHHHHHHHHHCCCCCCCCEEEEECCCEEEEECCCCCEEEEEEEEECCCCCCHH LFDFGLYFFHNAHELLARNTGPYFYLPKLESHLEARLWNDVFNFAQDRLGIPRGTIRATV HHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH LIETILAAFEMDEILWELRDHAAGLNAGRWDYIFSVIKKFRRHREFLLPDRAQVTMTVPF HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHH MRAYTELLVRTCHRRGAHAIGGMAAFIPSRRDPQVNEIALAKVREDKEREAKDGFDGTWV HHHHHHHHHHHHHHCCCHHHCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEE AHPDLVPVALEVFDRVLGEQPHQKHRLREDVQVTARDLLDVRVPGGRITEGGLRNNVSVA ECCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCHHHHH LQYLDSWLRGQGAAAIFNLMEDTATAEISRAQLWQWRFHRAELDDGRPVTAELYVQIRDE HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEECHH ELTKLGGEVAGRLREAREILDRLVLDDEFTEFLTYLAYEYID HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCC >Mature Secondary Structure GDVRIVGRMTPEFAQILTEPALDFVASLHREFNLRRKQLLERRAERQQAIDAGHFPDFL CCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC PETAHIRESEWRVAPTPPDLEDRRVEITGPVDRKMMINALNSGARVFMADFEDALSPTWD CCCCCCCCCCCEECCCCCCCCCCEEEEECCCCHHHHHHHHCCCCEEEEECHHHHCCCCHH NVVQGQINLRDAVRRTISFESPDGRVYRLADKTATLVVRPRGWHLVERHVLVDGEPISAS HHHCCCCCHHHHHHHHHCCCCCCCCEEEEECCCEEEEECCCCCEEEEEEEEECCCCCCHH LFDFGLYFFHNAHELLARNTGPYFYLPKLESHLEARLWNDVFNFAQDRLGIPRGTIRATV HHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH LIETILAAFEMDEILWELRDHAAGLNAGRWDYIFSVIKKFRRHREFLLPDRAQVTMTVPF HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHH MRAYTELLVRTCHRRGAHAIGGMAAFIPSRRDPQVNEIALAKVREDKEREAKDGFDGTWV HHHHHHHHHHHHHHCCCHHHCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEE AHPDLVPVALEVFDRVLGEQPHQKHRLREDVQVTARDLLDVRVPGGRITEGGLRNNVSVA ECCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCHHHHH LQYLDSWLRGQGAAAIFNLMEDTATAEISRAQLWQWRFHRAELDDGRPVTAELYVQIRDE HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEECHH ELTKLGGEVAGRLREAREILDRLVLDDEFTEFLTYLAYEYID HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA