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The map label for this gene is sufB [H]

Identifier: 221632408

GI number: 221632408

Start: 382121

End: 383536

Strand: Reverse

Name: sufB [H]

Synonym: trd_0380

Alternate gene names: 221632408

Gene position: 383536-382121 (Counterclockwise)

Preceding gene: 221632409

Following gene: 221632407

Centisome position: 19.15

GC content: 61.02

Gene sequence:

>1416_bases
ATGACGACACCAGAAGTCGAACTCAAGCGATTGGGAAGCGAGTACGCCGAAAAGTACGGGTTCCGCGACCCCGAGCAGTA
TGTCTTCAAAGCCCGCAAGGGCCTCGATCGGGAGGTCGTGGAGCAGATCTCCTGGATCAAGAATGAGCCGGAGTGGATGC
GCGAGTTCCGGCTCAAGGCACTCGAATACTTTCTGCGGCGCCCGATGCCGACCTGGGGCGCGGACCTGTCCGAACTGAAC
TTCGACGAGATCGTCTATTACATCAAACCAACCGAGCGACAGGGTACGAGCTGGGAGGAACTGCCCGAGCACATCCGCCG
CACGTTCGATCGGTTGGGTATTCCGGAAGCCGAGCGGCGTTTCCTCGCTGGAGTCGGCGCCCAGTACGAGTCGGAGGTCG
TCTACCACTCGCTCCGCGAGGAACTCAAGCGGCTCGGCGTGATCTTCTGCGATATGGACACGGCCGTCCGCGAATATCCG
GACCTGGTCAAGCAGTACTTCGGGACTATCGTGCCACCAAACGACAACAAGTTCGCTGCCCTCAACTCGGCCGTCTGGTC
GGGTGGCTCCTTCGTCTATGTCCCCGAGGGGGTGCGGGTCGACGTACCGCTCCAGGCCTACTTCCGCATCAATGCCGAGA
ACGTGGGGCAGTTCGAGCGCACGCTCATCATCGTCGAGCCTGGTGCCTACGTCCACTACGTGGAAGGTTGCACCGCTCCG
ATTTACAGCGCTGCCTCGCTGCACAGCGCAGTCGTCGAGATCATCGTCAAAGAAGGTGCACGCTGCCGGTACACGACCAT
CCAGAACTGGTCGAAGAACGTGTACAACCTCGTGACCAAGCGAGCAGCCGCGTACCGTGATGCCACCATGGAGTGGGTGG
ATGGGAATCTCGGCTCCAAGGTCACCATGAAGTACCCGGCTGTGTGGTTGATGGAGCCGGGCGCCCGCGGTGAAGTACTC
TCGGTCGCCTTCGCTGGTGATGGTCAGCACCAGGATGCCGGCGGCAAGATGGTGCACGTCGCACCGTACACCTCATCCCA
GATCATCTCCAAGTCGATCTCCAAAGGGACTGGCCGGGCCAGTTACCGCGGTTTGGTCAAGGTGCATCGCGGCGCCCACC
ATGTGCGCGCCAACGTGGTGTGCGACGCGCTCCTGCTCGACGAGCAGAGCCGCACGGATACCTACCCGTATATGGAGATC
GAAGAGGAGCAGGTGTCGATCGGTCATGAGGCAACGGTGAGCAAGGTGGCCGAGGAACAGCTCTTCTACCTGCAGAGTCG
GGGGCTCACCGAAGCCGAGGCGATGAGCATGATCGTCAACGGCTTCATCGAGCCGATCACGAAGGAACTGCCGCTGGAGT
ACGCGGTCGAGCTGAACCGGCTGATCGCGCTCGAGATGGAAGGTTCAGTCGGATGA

Upstream 100 bases:

>100_bases
AACTGGCTGAAGAACTCGAAGAGAAAGGGTACGACTGGGTCAAGGAGCAGTTCGCGGAAGCGGCCTCCTGACCGAGCCGT
ACCATAAGGAGGAACGTGCC

Downstream 100 bases:

>100_bases
GACGCAGGCGGTCTGGCTCGGTCCAGACCGCCGCACCGTCACCTGAGGGGAGATCATGAGCACGAGGGTCGCAGAACGAA
CACGAGGCTTCACGCGTGAG

Product: FeS assembly protein SufB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 471; Mature: 470

Protein sequence:

>471_residues
MTTPEVELKRLGSEYAEKYGFRDPEQYVFKARKGLDREVVEQISWIKNEPEWMREFRLKALEYFLRRPMPTWGADLSELN
FDEIVYYIKPTERQGTSWEELPEHIRRTFDRLGIPEAERRFLAGVGAQYESEVVYHSLREELKRLGVIFCDMDTAVREYP
DLVKQYFGTIVPPNDNKFAALNSAVWSGGSFVYVPEGVRVDVPLQAYFRINAENVGQFERTLIIVEPGAYVHYVEGCTAP
IYSAASLHSAVVEIIVKEGARCRYTTIQNWSKNVYNLVTKRAAAYRDATMEWVDGNLGSKVTMKYPAVWLMEPGARGEVL
SVAFAGDGQHQDAGGKMVHVAPYTSSQIISKSISKGTGRASYRGLVKVHRGAHHVRANVVCDALLLDEQSRTDTYPYMEI
EEEQVSIGHEATVSKVAEEQLFYLQSRGLTEAEAMSMIVNGFIEPITKELPLEYAVELNRLIALEMEGSVG

Sequences:

>Translated_471_residues
MTTPEVELKRLGSEYAEKYGFRDPEQYVFKARKGLDREVVEQISWIKNEPEWMREFRLKALEYFLRRPMPTWGADLSELN
FDEIVYYIKPTERQGTSWEELPEHIRRTFDRLGIPEAERRFLAGVGAQYESEVVYHSLREELKRLGVIFCDMDTAVREYP
DLVKQYFGTIVPPNDNKFAALNSAVWSGGSFVYVPEGVRVDVPLQAYFRINAENVGQFERTLIIVEPGAYVHYVEGCTAP
IYSAASLHSAVVEIIVKEGARCRYTTIQNWSKNVYNLVTKRAAAYRDATMEWVDGNLGSKVTMKYPAVWLMEPGARGEVL
SVAFAGDGQHQDAGGKMVHVAPYTSSQIISKSISKGTGRASYRGLVKVHRGAHHVRANVVCDALLLDEQSRTDTYPYMEI
EEEQVSIGHEATVSKVAEEQLFYLQSRGLTEAEAMSMIVNGFIEPITKELPLEYAVELNRLIALEMEGSVG
>Mature_470_residues
TTPEVELKRLGSEYAEKYGFRDPEQYVFKARKGLDREVVEQISWIKNEPEWMREFRLKALEYFLRRPMPTWGADLSELNF
DEIVYYIKPTERQGTSWEELPEHIRRTFDRLGIPEAERRFLAGVGAQYESEVVYHSLREELKRLGVIFCDMDTAVREYPD
LVKQYFGTIVPPNDNKFAALNSAVWSGGSFVYVPEGVRVDVPLQAYFRINAENVGQFERTLIIVEPGAYVHYVEGCTAPI
YSAASLHSAVVEIIVKEGARCRYTTIQNWSKNVYNLVTKRAAAYRDATMEWVDGNLGSKVTMKYPAVWLMEPGARGEVLS
VAFAGDGQHQDAGGKMVHVAPYTSSQIISKSISKGTGRASYRGLVKVHRGAHHVRANVVCDALLLDEQSRTDTYPYMEIE
EEQVSIGHEATVSKVAEEQLFYLQSRGLTEAEAMSMIVNGFIEPITKELPLEYAVELNRLIALEMEGSVG

Specific function: The sufBCD complex acts synergistically with sufE to stimulate the cysteine desulfurase activity of sufS. The sufBCD complex contributes to the assembly or repair of oxygen-labile iron-sulfur clusters under oxidative stress. May facilitate iron uptake fro

COG id: COG0719

COG function: function code O; ABC-type transport system involved in Fe-S cluster assembly, permease component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0051 (ycf24) family [H]

Homologues:

Organism=Escherichia coli, GI87081955, Length=461, Percent_Identity=42.2993492407809, Blast_Score=377, Evalue=1e-105,
Organism=Escherichia coli, GI1787971, Length=112, Percent_Identity=33.0357142857143, Blast_Score=74, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010231
- InterPro:   IPR000825 [H]

Pfam domain/function: PF01458 UPF0051 [H]

EC number: NA

Molecular weight: Translated: 53386; Mature: 53255

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTPEVELKRLGSEYAEKYGFRDPEQYVFKARKGLDREVVEQISWIKNEPEWMREFRLKA
CCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHH
LEYFLRRPMPTWGADLSELNFDEIVYYIKPTERQGTSWEELPEHIRRTFDRLGIPEAERR
HHHHHHCCCCCCCCCHHHCCHHHEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHH
FLAGVGAQYESEVVYHSLREELKRLGVIFCDMDTAVREYPDLVKQYFGTIVPPNDNKFAA
HHHHCCCCHHHHHHHHHHHHHHHHCCEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCEEE
LNSAVWSGGSFVYVPEGVRVDVPLQAYFRINAENVGQFERTLIIVEPGAYVHYVEGCTAP
EHHHHCCCCCEEEECCCCEECCCEEEEEEECCHHCCCEEEEEEEECCCCEEEEECCCCCH
IYSAASLHSAVVEIIVKEGARCRYTTIQNWSKNVYNLVTKRAAAYRDATMEWVDGNLGSK
HHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCCE
VTMKYPAVWLMEPGARGEVLSVAFAGDGQHQDAGGKMVHVAPYTSSQIISKSISKGTGRA
EEEECCEEEEECCCCCCCEEEEEEECCCCCCCCCCCEEEEECCCHHHHHHHHHHCCCCCH
SYRGLVKVHRGAHHVRANVVCDALLLDEQSRTDTYPYMEIEEEQVSIGHEATVSKVAEEQ
HHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEECHHHHHCCCHHHHHHHHHHH
LFYLQSRGLTEAEAMSMIVNGFIEPITKELPLEYAVELNRLIALEMEGSVG
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCEEEEEECCCCC
>Mature Secondary Structure 
TTPEVELKRLGSEYAEKYGFRDPEQYVFKARKGLDREVVEQISWIKNEPEWMREFRLKA
CCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHH
LEYFLRRPMPTWGADLSELNFDEIVYYIKPTERQGTSWEELPEHIRRTFDRLGIPEAERR
HHHHHHCCCCCCCCCHHHCCHHHEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHH
FLAGVGAQYESEVVYHSLREELKRLGVIFCDMDTAVREYPDLVKQYFGTIVPPNDNKFAA
HHHHCCCCHHHHHHHHHHHHHHHHCCEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCEEE
LNSAVWSGGSFVYVPEGVRVDVPLQAYFRINAENVGQFERTLIIVEPGAYVHYVEGCTAP
EHHHHCCCCCEEEECCCCEECCCEEEEEEECCHHCCCEEEEEEEECCCCEEEEECCCCCH
IYSAASLHSAVVEIIVKEGARCRYTTIQNWSKNVYNLVTKRAAAYRDATMEWVDGNLGSK
HHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCCE
VTMKYPAVWLMEPGARGEVLSVAFAGDGQHQDAGGKMVHVAPYTSSQIISKSISKGTGRA
EEEECCEEEEECCCCCCCEEEEEEECCCCCCCCCCCEEEEECCCHHHHHHHHHHCCCCCH
SYRGLVKVHRGAHHVRANVVCDALLLDEQSRTDTYPYMEIEEEQVSIGHEATVSKVAEEQ
HHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEECHHHHHCCCHHHHHHHHHHH
LFYLQSRGLTEAEAMSMIVNGFIEPITKELPLEYAVELNRLIALEMEGSVG
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]