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The map label for this gene is lolC [H]

Identifier: 220933155

GI number: 220933155

Start: 2541639

End: 2542898

Strand: Reverse

Name: lolC [H]

Synonym: Hore_23230

Alternate gene names: 220933155

Gene position: 2542898-2541639 (Counterclockwise)

Preceding gene: 220933156

Following gene: 220933154

Centisome position: 98.63

GC content: 44.05

Gene sequence:

>1260_bases
GTGAAATATCTGGCAAAACTGGCCTATAAAAACCTTTACCGGCAAAAACTGAGGACGGCTGTTTCCATTGCTGCTATTGT
CTTCTCGGTTGCGGTGGTTGTTTTTGCCCGGGGTTTGATTTCTGGTTTTATAGGATCGATTTATTCTGATTATATATATT
ATGACAGTGGCCATATTAGAATTGTTAAACAGGAATACTTAAAAAAAGAGAGGTTATTATCACTGGCCTATCCGGTTGAT
GGTTTTGAGGGGGAAGGCATATCCTCGATGGTGGCCAGACTGGAAGAACTGGAAGGTATAAATATGGCTTTGCCCCGGCT
TAAATTTGGGGCAGTTGTCAGTACTGATGATGAACTTATTAAGATGATGGGCTGGGGTGTTGATCCGGAGAAGGAAAAGG
AGTTTACTGATATTGATGAACTACTGGTTGAAGGCAGGTTTCCCCGACGGGGCATGAAAGAGATTGTGCTTGGTTCTGAG
CTTCTGGCCAAACTGGATAAAGGAGTGGGGGAAAAGGTTACGGTTTTATATACCACATCATTTAATTCATTTCAGGCCAC
TACCTTTAAAATTGTAGGGCGGATTGAAAGTGGATTAAAACTTTTGAATGAGACTGTTTTTATGGTTCCCCTTGATGTGG
CTCAAAAGGCCCTTTATATGCCGGACCAGGCTACTGAACTACTGCTGGTGACTCCGGATTTAAACAGGGCAGGTGAATAT
CTCCCCGGTATCAGGAAAGTCTTTGAGAGGCAGGGTGGACTGAACAATTATGCCATCCGGGCCTGGGATGATTCCAGTGG
TATGATCAGGTTGATGAAAATGGCTGAAAACATTTATAATGTGATTTATGTTTTCCTGGTAGTTTTAGCGAGTTTTGTGG
TTATTAATTCAATGATTATGATTGTTAAGGAGAGAACCCGGGAGATTGGAATGATGTCTGCCCTGGGACTGGGGAAAAGG
CAGATACTGCAGCTTTTCGTTCTTGAAGGTGGAGTTATGGGTGTGGTCGGTAGTTTTATCGGGGCTTTACTGGGTGGTTT
AATTACCAGAGTGGTGGCGGTGACAGGAATTGATTACACCAAAGCCCTGGAAGGAATGGGAGAAGATATTTTGATGCGTC
CGGTAATCTATCCCGTCTTCTCTTTTGACAATATGATATTTGCCTTTGTCCTGGGTGTTGTAGTTACTTCCCTGGCGTGC
CTTATTCCGGCCAGGAGGGCAGCCCGTCTTAAGCCAACTGAAGCCCTGCGTGAAATATAG

Upstream 100 bases:

>100_bases
AGTGTTATTGTATCCCTGCTGGTCAGTATTTTTCCAGCACGATGGGCCGCCCGAAAGGATCCGGTTAAGGCTATCTATCA
CCGTTAGGGGGTGAGTTGAA

Downstream 100 bases:

>100_bases
TACACCGGTGAGAGAAGAAAAATTTAATTTTAAGGGGGTAAAGGAAATGTTTAATAAAACTACTAGAATACTATTACTGA
TAATGACAATGACTGTTGTG

Product: lipoprotein release ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 419; Mature: 419

Protein sequence:

>419_residues
MKYLAKLAYKNLYRQKLRTAVSIAAIVFSVAVVVFARGLISGFIGSIYSDYIYYDSGHIRIVKQEYLKKERLLSLAYPVD
GFEGEGISSMVARLEELEGINMALPRLKFGAVVSTDDELIKMMGWGVDPEKEKEFTDIDELLVEGRFPRRGMKEIVLGSE
LLAKLDKGVGEKVTVLYTTSFNSFQATTFKIVGRIESGLKLLNETVFMVPLDVAQKALYMPDQATELLLVTPDLNRAGEY
LPGIRKVFERQGGLNNYAIRAWDDSSGMIRLMKMAENIYNVIYVFLVVLASFVVINSMIMIVKERTREIGMMSALGLGKR
QILQLFVLEGGVMGVVGSFIGALLGGLITRVVAVTGIDYTKALEGMGEDILMRPVIYPVFSFDNMIFAFVLGVVVTSLAC
LIPARRAARLKPTEALREI

Sequences:

>Translated_419_residues
MKYLAKLAYKNLYRQKLRTAVSIAAIVFSVAVVVFARGLISGFIGSIYSDYIYYDSGHIRIVKQEYLKKERLLSLAYPVD
GFEGEGISSMVARLEELEGINMALPRLKFGAVVSTDDELIKMMGWGVDPEKEKEFTDIDELLVEGRFPRRGMKEIVLGSE
LLAKLDKGVGEKVTVLYTTSFNSFQATTFKIVGRIESGLKLLNETVFMVPLDVAQKALYMPDQATELLLVTPDLNRAGEY
LPGIRKVFERQGGLNNYAIRAWDDSSGMIRLMKMAENIYNVIYVFLVVLASFVVINSMIMIVKERTREIGMMSALGLGKR
QILQLFVLEGGVMGVVGSFIGALLGGLITRVVAVTGIDYTKALEGMGEDILMRPVIYPVFSFDNMIFAFVLGVVVTSLAC
LIPARRAARLKPTEALREI
>Mature_419_residues
MKYLAKLAYKNLYRQKLRTAVSIAAIVFSVAVVVFARGLISGFIGSIYSDYIYYDSGHIRIVKQEYLKKERLLSLAYPVD
GFEGEGISSMVARLEELEGINMALPRLKFGAVVSTDDELIKMMGWGVDPEKEKEFTDIDELLVEGRFPRRGMKEIVLGSE
LLAKLDKGVGEKVTVLYTTSFNSFQATTFKIVGRIESGLKLLNETVFMVPLDVAQKALYMPDQATELLLVTPDLNRAGEY
LPGIRKVFERQGGLNNYAIRAWDDSSGMIRLMKMAENIYNVIYVFLVVLASFVVINSMIMIVKERTREIGMMSALGLGKR
QILQLFVLEGGVMGVVGSFIGALLGGLITRVVAVTGIDYTKALEGMGEDILMRPVIYPVFSFDNMIFAFVLGVVVTSLAC
LIPARRAARLKPTEALREI

Specific function: Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787362, Length=338, Percent_Identity=23.9644970414201, Blast_Score=73, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 46573; Mature: 46573

Theoretical pI: Translated: 8.98; Mature: 8.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYLAKLAYKNLYRQKLRTAVSIAAIVFSVAVVVFARGLISGFIGSIYSDYIYYDSGHIR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCEE
IVKQEYLKKERLLSLAYPVDGFEGEGISSMVARLEELEGINMALPRLKFGAVVSTDDELI
EHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCHHCCCHHHCCEECCHHHHH
KMMGWGVDPEKEKEFTDIDELLVEGRFPRRGMKEIVLGSELLAKLDKGVGEKVTVLYTTS
HHHCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEEEC
FNSFQATTFKIVGRIESGLKLLNETVFMVPLDVAQKALYMPDQATELLLVTPDLNRAGEY
CCCCHHHHHHHHHHHHHHHHHHHHHHEEEEHHHHHHHHCCCCCCCEEEEECCCCCCCHHH
LPGIRKVFERQGGLNNYAIRAWDDSSGMIRLMKMAENIYNVIYVFLVVLASFVVINSMIM
HHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVKERTREIGMMSALGLGKRQILQLFVLEGGVMGVVGSFIGALLGGLITRVVAVTGIDYT
HHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
KALEGMGEDILMRPVIYPVFSFDNMIFAFVLGVVVTSLACLIPARRAARLKPTEALREI
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCC
>Mature Secondary Structure
MKYLAKLAYKNLYRQKLRTAVSIAAIVFSVAVVVFARGLISGFIGSIYSDYIYYDSGHIR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCEE
IVKQEYLKKERLLSLAYPVDGFEGEGISSMVARLEELEGINMALPRLKFGAVVSTDDELI
EHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCHHCCCHHHCCEECCHHHHH
KMMGWGVDPEKEKEFTDIDELLVEGRFPRRGMKEIVLGSELLAKLDKGVGEKVTVLYTTS
HHHCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEEEC
FNSFQATTFKIVGRIESGLKLLNETVFMVPLDVAQKALYMPDQATELLLVTPDLNRAGEY
CCCCHHHHHHHHHHHHHHHHHHHHHHEEEEHHHHHHHHCCCCCCCEEEEECCCCCCCHHH
LPGIRKVFERQGGLNNYAIRAWDDSSGMIRLMKMAENIYNVIYVFLVVLASFVVINSMIM
HHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVKERTREIGMMSALGLGKRQILQLFVLEGGVMGVVGSFIGALLGGLITRVVAVTGIDYT
HHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
KALEGMGEDILMRPVIYPVFSFDNMIFAFVLGVVVTSLACLIPARRAARLKPTEALREI
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]