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The map label for this gene is macB [H]

Identifier: 220933156

GI number: 220933156

Start: 2542912

End: 2544159

Strand: Reverse

Name: macB [H]

Synonym: Hore_23240

Alternate gene names: 220933156

Gene position: 2544159-2542912 (Counterclockwise)

Preceding gene: 220933157

Following gene: 220933155

Centisome position: 98.68

GC content: 44.07

Gene sequence:

>1248_bases
ATGTTTCTGGTTAAACTGGCTTTTAAGAACCTGACCCGCCACCGGAAAAGAACCCTGATTACAGCAGCTGTAATTGCCCT
GGCAGTGGTTATTTACCTGATGACCGATTCCCTCCTTATAGGGATGGTAGATAAATCTTTTGAAAATGTTATCGATTTTG
AGTCAGGCCACATTCAGATTGTTAATCAAAATTACTGGGAGGAGAGGGAGGACCTGCCCCTTAAAAATTTAATCAGGCCT
GACAGGGAATTATTAACTTTTCTCCAAAAGGTAGATGGTTTAAAGGGTTTGACCCCGGTGTTGACCTTCAGTGCTACCCT
GAATAACGGTATTGAAGAGATACCGGTAGTGGCCCAGGGAATCGATCCTCAAAGTTATTCACAGGTTTTAAGGGCAGGGG
AGTATCTTGTTGAGGGTGAATTTTTGACAGGAAATAAGTCCACCGCGGTCATGGGTAAAACCCTGGCCAAGTTGATGGAT
TTAAAAACAGGGGACTATATAACTCTGGTAATTAAAAGTAAAGAAGGAACCTTTAATACAATAGATGTTCAGATATCTGG
TCTGGTTGATTCACCCAACCCCAGTATCAATGAAAATATTGTTTTTGTTCCCCTTGAAATAGCCCGGCAGGCTTTAAATG
TCAGGGGCATGGTCAGTCAGATAATTATCAGGGTAGAAGACAGGATAAGAGCCGTCGAGACAGCGAGGTTGTTATCAGAT
GATTTGCAAGAAGCCGGATCTTCTTTAAGGGCCTTCTCCTGGCGTAAGTCGGCCGAGTACATTGTAGCCCTGAACAAAGC
CGAGAGGGTTGAAACCCAGATGATATTAGGTATTATTCTGTTAATAGCAGCTATAGGAATAATCAATTTCGTTGTCCTGG
CTGCCCTGGAAAGAATGGAAGAAATCGGGATGATGAAGGCCCTTGGACTGAAACAGTGGGAGATAGTTATCGTTTTTGTT
ATGGAAGCTGTTGGAGTCAGCCTTATTGGAGGTATCATTGGATGCCTTGTGGGTGGAGCGGTCGTTGCCTATTTAGTTTT
TTATGGAGTGGATATATTTTCCCTGGGAGGGGAAGATGCCATCAGTTCCATGGGTATCCCTGTCCTGGGACGGATATACG
GGGGCTTTAATCCCGGTTCCTTCATCTTTGTTTTTAGTTATAGTGTTATTGTATCCCTGCTGGTCAGTATTTTTCCAGCA
CGATGGGCCGCCCGAAAGGATCCGGTTAAGGCTATCTATCACCGTTAG

Upstream 100 bases:

>100_bases
ATTTTTTCCACCCATGACCCCCGGGTTATGAATTATGCCCGGAGGCTAATTGAAATCAGGGATGGTCGGGTTACCAGGGA
TGAAAGGAGGAAAGGCCAGG

Downstream 100 bases:

>100_bases
GGGGTGAGTTGAAGTGAAATATCTGGCAAAACTGGCCTATAAAAACCTTTACCGGCAAAAACTGAGGACGGCTGTTTCCA
TTGCTGCTATTGTCTTCTCG

Product: lipoprotein release ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 415; Mature: 415

Protein sequence:

>415_residues
MFLVKLAFKNLTRHRKRTLITAAVIALAVVIYLMTDSLLIGMVDKSFENVIDFESGHIQIVNQNYWEEREDLPLKNLIRP
DRELLTFLQKVDGLKGLTPVLTFSATLNNGIEEIPVVAQGIDPQSYSQVLRAGEYLVEGEFLTGNKSTAVMGKTLAKLMD
LKTGDYITLVIKSKEGTFNTIDVQISGLVDSPNPSINENIVFVPLEIARQALNVRGMVSQIIIRVEDRIRAVETARLLSD
DLQEAGSSLRAFSWRKSAEYIVALNKAERVETQMILGIILLIAAIGIINFVVLAALERMEEIGMMKALGLKQWEIVIVFV
MEAVGVSLIGGIIGCLVGGAVVAYLVFYGVDIFSLGGEDAISSMGIPVLGRIYGGFNPGSFIFVFSYSVIVSLLVSIFPA
RWAARKDPVKAIYHR

Sequences:

>Translated_415_residues
MFLVKLAFKNLTRHRKRTLITAAVIALAVVIYLMTDSLLIGMVDKSFENVIDFESGHIQIVNQNYWEEREDLPLKNLIRP
DRELLTFLQKVDGLKGLTPVLTFSATLNNGIEEIPVVAQGIDPQSYSQVLRAGEYLVEGEFLTGNKSTAVMGKTLAKLMD
LKTGDYITLVIKSKEGTFNTIDVQISGLVDSPNPSINENIVFVPLEIARQALNVRGMVSQIIIRVEDRIRAVETARLLSD
DLQEAGSSLRAFSWRKSAEYIVALNKAERVETQMILGIILLIAAIGIINFVVLAALERMEEIGMMKALGLKQWEIVIVFV
MEAVGVSLIGGIIGCLVGGAVVAYLVFYGVDIFSLGGEDAISSMGIPVLGRIYGGFNPGSFIFVFSYSVIVSLLVSIFPA
RWAARKDPVKAIYHR
>Mature_415_residues
MFLVKLAFKNLTRHRKRTLITAAVIALAVVIYLMTDSLLIGMVDKSFENVIDFESGHIQIVNQNYWEEREDLPLKNLIRP
DRELLTFLQKVDGLKGLTPVLTFSATLNNGIEEIPVVAQGIDPQSYSQVLRAGEYLVEGEFLTGNKSTAVMGKTLAKLMD
LKTGDYITLVIKSKEGTFNTIDVQISGLVDSPNPSINENIVFVPLEIARQALNVRGMVSQIIIRVEDRIRAVETARLLSD
DLQEAGSSLRAFSWRKSAEYIVALNKAERVETQMILGIILLIAAIGIINFVVLAALERMEEIGMMKALGLKQWEIVIVFV
MEAVGVSLIGGIIGCLVGGAVVAYLVFYGVDIFSLGGEDAISSMGIPVLGRIYGGFNPGSFIFVFSYSVIVSLLVSIFPA
RWAARKDPVKAIYHR

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787362, Length=282, Percent_Identity=23.4042553191489, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787105, Length=216, Percent_Identity=25, Blast_Score=66, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 45701; Mature: 45701

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLVKLAFKNLTRHRKRTLITAAVIALAVVIYLMTDSLLIGMVDKSFENVIDFESGHIQI
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
VNQNYWEEREDLPLKNLIRPDRELLTFLQKVDGLKGLTPVLTFSATLNNGIEEIPVVAQG
ECCCCCCHHCCCCHHHHCCCCHHHHHHHHHHCCCCCCCHHHEEHHHHHCCHHHCCHHHCC
IDPQSYSQVLRAGEYLVEGEFLTGNKSTAVMGKTLAKLMDLKTGDYITLVIKSKEGTFNT
CCHHHHHHHHHCCCCEEECEEEECCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEE
IDVQISGLVDSPNPSINENIVFVPLEIARQALNVRGMVSQIIIRVEDRIRAVETARLLSD
EEEEEEEEECCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLQEAGSSLRAFSWRKSAEYIVALNKAERVETQMILGIILLIAAIGIINFVVLAALERME
HHHHHCCHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EIGMMKALGLKQWEIVIVFVMEAVGVSLIGGIIGCLVGGAVVAYLVFYGVDIFSLGGEDA
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEECCCHHH
ISSMGIPVLGRIYGGFNPGSFIFVFSYSVIVSLLVSIFPARWAARKDPVKAIYHR
HHHCCCCHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCC
>Mature Secondary Structure
MFLVKLAFKNLTRHRKRTLITAAVIALAVVIYLMTDSLLIGMVDKSFENVIDFESGHIQI
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
VNQNYWEEREDLPLKNLIRPDRELLTFLQKVDGLKGLTPVLTFSATLNNGIEEIPVVAQG
ECCCCCCHHCCCCHHHHCCCCHHHHHHHHHHCCCCCCCHHHEEHHHHHCCHHHCCHHHCC
IDPQSYSQVLRAGEYLVEGEFLTGNKSTAVMGKTLAKLMDLKTGDYITLVIKSKEGTFNT
CCHHHHHHHHHCCCCEEECEEEECCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEE
IDVQISGLVDSPNPSINENIVFVPLEIARQALNVRGMVSQIIIRVEDRIRAVETARLLSD
EEEEEEEEECCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLQEAGSSLRAFSWRKSAEYIVALNKAERVETQMILGIILLIAAIGIINFVVLAALERME
HHHHHCCHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EIGMMKALGLKQWEIVIVFVMEAVGVSLIGGIIGCLVGGAVVAYLVFYGVDIFSLGGEDA
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEECCCHHH
ISSMGIPVLGRIYGGFNPGSFIFVFSYSVIVSLLVSIFPARWAARKDPVKAIYHR
HHHCCCCHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]