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The map label for this gene is nagA [H]

Identifier: 220933125

GI number: 220933125

Start: 2503736

End: 2504875

Strand: Reverse

Name: nagA [H]

Synonym: Hore_22930

Alternate gene names: 220933125

Gene position: 2504875-2503736 (Counterclockwise)

Preceding gene: 220933126

Following gene: 220933124

Centisome position: 97.16

GC content: 47.63

Gene sequence:

>1140_bases
TTGAAAGCACTTAAAAATATTAAACTGGTTACAATAGAAGGGATTTTTACCGGGAAAGCGGTCCTTTTTGAAGATAGGAT
TGAGAAGATAATTGCTGAGGAAGAAGTTGAAGGGTTAAAAGTTAATGGCCTTGAGGTTATTGATGGGGAGGGGAATTACC
TTGCGCCGGGTTTTATTGATATCCATACTCATGGAGCGGCAGGTTATGATACCATGGACGGCAACTATGAAGCCCTCAAC
AATTATTCAAAGGCCATCGTCCGGACCGGGGTTACTTCCTTTACACCGACGACAATGGCCATGCCGGAGGAGAGGATCAC
AAAGGCCCTGGATGCTGTAAGGCAAGCCCGGGCAAAAGGGGTAGAGGGAGCAAAAATTTTGGGTGTTTATATGGAAAGCC
CCTTTATCAGTCCCGGGTACCGTGGTTGCCAGGCCAGGGAGGCCATTAAGGAACCGGCTATATCATTTTTAAAGGATTAT
ACAGATGTTGTTAAAGTTGTGACCCTGGCTCCAGAAAGGGAAGGGGCCAGGAAGTTAGTGGAGTTTTTAAGGGAAAATGG
TATTGTGGCGTCGGTCGGCCATTCTGCCGCCAGTTATGATGATGTCATTAGAGCCCGGGAGTGGGGAATAAGTCACGCCA
CCCATCTCTTTAACGCCATGACAGGGTTACACCACCGGAGACCGGGTATAGTGGGGGCGGTACTAACTACAGATCTGACC
TGTGAGCTTATCGCCGATTTAATCCATATCCATCCAGCTGCCCTTAACCTGGTGTTCAAAGCAAAGGACTGGGAGGATAT
TATCCTGGTTACCGATCAGATGGAGGCTACTACTTTAGAGGATGGCACCTACGAACTGGGAGGACAGAAGGTTATAGTTA
AAGAGGATTCAGCCCGTCTAGAGGATGGTACCCTGGCGGGAAGCATTTTGACTCTGGACAGGGCCCTCAGCAATATTGTA
AAGATAAGTGACCTTCCCCTCCACCGGGTTATTGCCATGATAACTTCAAACCCGGCCCGGCTTCTGGGGGTCGCTGATGA
GATAGGTAGTATTGCCCCCGGCTACCGGGCTGATATGGTTTTACTTGATAAAGAACTTAAAGTAAACAAGGTTTTTGTAG
ATGGAGAAATCAAATGTTAA

Upstream 100 bases:

>100_bases
CCCCAATTGAATATACCAGGGCTCATTACCGCAGTGATGAGTATAAATTTAAATTAAAATTTAATTTTAAAGAAGGGTGA
CCGACAGGAGGGATACATCT

Downstream 100 bases:

>100_bases
ATTTACATTAAATTTTAATCAGGGAGGTAGGATAATGAGGGTTCTTATAGAAGAAAATTACCGGGAGATGAGTAAAAAAG
CGGCTTTACTGGTAGCAAGC

Product: N-acetylglucosamine-6-phosphate deacetylase

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 379; Mature: 379

Protein sequence:

>379_residues
MKALKNIKLVTIEGIFTGKAVLFEDRIEKIIAEEEVEGLKVNGLEVIDGEGNYLAPGFIDIHTHGAAGYDTMDGNYEALN
NYSKAIVRTGVTSFTPTTMAMPEERITKALDAVRQARAKGVEGAKILGVYMESPFISPGYRGCQAREAIKEPAISFLKDY
TDVVKVVTLAPEREGARKLVEFLRENGIVASVGHSAASYDDVIRAREWGISHATHLFNAMTGLHHRRPGIVGAVLTTDLT
CELIADLIHIHPAALNLVFKAKDWEDIILVTDQMEATTLEDGTYELGGQKVIVKEDSARLEDGTLAGSILTLDRALSNIV
KISDLPLHRVIAMITSNPARLLGVADEIGSIAPGYRADMVLLDKELKVNKVFVDGEIKC

Sequences:

>Translated_379_residues
MKALKNIKLVTIEGIFTGKAVLFEDRIEKIIAEEEVEGLKVNGLEVIDGEGNYLAPGFIDIHTHGAAGYDTMDGNYEALN
NYSKAIVRTGVTSFTPTTMAMPEERITKALDAVRQARAKGVEGAKILGVYMESPFISPGYRGCQAREAIKEPAISFLKDY
TDVVKVVTLAPEREGARKLVEFLRENGIVASVGHSAASYDDVIRAREWGISHATHLFNAMTGLHHRRPGIVGAVLTTDLT
CELIADLIHIHPAALNLVFKAKDWEDIILVTDQMEATTLEDGTYELGGQKVIVKEDSARLEDGTLAGSILTLDRALSNIV
KISDLPLHRVIAMITSNPARLLGVADEIGSIAPGYRADMVLLDKELKVNKVFVDGEIKC
>Mature_379_residues
MKALKNIKLVTIEGIFTGKAVLFEDRIEKIIAEEEVEGLKVNGLEVIDGEGNYLAPGFIDIHTHGAAGYDTMDGNYEALN
NYSKAIVRTGVTSFTPTTMAMPEERITKALDAVRQARAKGVEGAKILGVYMESPFISPGYRGCQAREAIKEPAISFLKDY
TDVVKVVTLAPEREGARKLVEFLRENGIVASVGHSAASYDDVIRAREWGISHATHLFNAMTGLHHRRPGIVGAVLTTDLT
CELIADLIHIHPAALNLVFKAKDWEDIILVTDQMEATTLEDGTYELGGQKVIVKEDSARLEDGTLAGSILTLDRALSNIV
KISDLPLHRVIAMITSNPARLLGVADEIGSIAPGYRADMVLLDKELKVNKVFVDGEIKC

Specific function: N-acetylglucosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI21361513, Length=381, Percent_Identity=31.758530183727, Blast_Score=156, Evalue=4e-38,
Organism=Homo sapiens, GI224922791, Length=381, Percent_Identity=31.496062992126, Blast_Score=154, Evalue=2e-37,
Organism=Escherichia coli, GI1786892, Length=335, Percent_Identity=31.044776119403, Blast_Score=153, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI17553768, Length=350, Percent_Identity=35.7142857142857, Blast_Score=197, Evalue=1e-50,
Organism=Drosophila melanogaster, GI19920392, Length=346, Percent_Identity=34.6820809248555, Blast_Score=177, Evalue=7e-45,
Organism=Drosophila melanogaster, GI281361140, Length=360, Percent_Identity=33.3333333333333, Blast_Score=171, Evalue=7e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 41295; Mature: 41295

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKALKNIKLVTIEGIFTGKAVLFEDRIEKIIAEEEVEGLKVNGLEVIDGEGNYLAPGFID
CCCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHCCCEEECCEEEEECCCCEECCCEEE
IHTHGAAGYDTMDGNYEALNNYSKAIVRTGVTSFTPTTMAMPEERITKALDAVRQARAKG
EEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHCCCHHHHHHHHHHHHHHHHCC
VEGAKILGVYMESPFISPGYRGCQAREAIKEPAISFLKDYTDVVKVVTLAPEREGARKLV
CCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
EFLRENGIVASVGHSAASYDDVIRAREWGISHATHLFNAMTGLHHRRPGIVGAVLTTDLT
HHHHHCCCEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEHHHHCHH
CELIADLIHIHPAALNLVFKAKDWEDIILVTDQMEATTLEDGTYELGGQKVIVKEDSARL
HHHHHHHHHHCHHHEEEEEECCCCCEEEEEECCCCCEEECCCCEECCCEEEEEECCCCCC
EDGTLAGSILTLDRALSNIVKISDLPLHRVIAMITSNPARLLGVADEIGSIAPGYRADMV
CCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHEEEEHHHHCCCCCCCCCCEE
LLDKELKVNKVFVDGEIKC
EEECCCEEEEEEECCEECC
>Mature Secondary Structure
MKALKNIKLVTIEGIFTGKAVLFEDRIEKIIAEEEVEGLKVNGLEVIDGEGNYLAPGFID
CCCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHCCCEEECCEEEEECCCCEECCCEEE
IHTHGAAGYDTMDGNYEALNNYSKAIVRTGVTSFTPTTMAMPEERITKALDAVRQARAKG
EEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHCCCHHHHHHHHHHHHHHHHCC
VEGAKILGVYMESPFISPGYRGCQAREAIKEPAISFLKDYTDVVKVVTLAPEREGARKLV
CCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
EFLRENGIVASVGHSAASYDDVIRAREWGISHATHLFNAMTGLHHRRPGIVGAVLTTDLT
HHHHHCCCEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEHHHHCHH
CELIADLIHIHPAALNLVFKAKDWEDIILVTDQMEATTLEDGTYELGGQKVIVKEDSARL
HHHHHHHHHHCHHHEEEEEECCCCCEEEEEECCCCCEEECCCCEECCCEEEEEECCCCCC
EDGTLAGSILTLDRALSNIVKISDLPLHRVIAMITSNPARLLGVADEIGSIAPGYRADMV
CCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHEEEEHHHHCCCCCCCCCCEE
LLDKELKVNKVFVDGEIKC
EEECCCEEEEEEECCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA