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The map label for this gene is malE [C]

Identifier: 220932811

GI number: 220932811

Start: 2128418

End: 2129689

Strand: Reverse

Name: malE [C]

Synonym: Hore_19770

Alternate gene names: 220932811

Gene position: 2129689-2128418 (Counterclockwise)

Preceding gene: 220932812

Following gene: 220932810

Centisome position: 82.61

GC content: 41.67

Gene sequence:

>1272_bases
ATGAAAAAGTTTTTTCTGTTGTTAGTATTAACAACTCTATTTGTTGGTACTCTGGCTGTTTCTGCAGGTGCTACCGAAAT
TACTATGTGGGCAATGAATAATGCTCCATCTGAATTAAACATTGCCTGGTTTAATGAAAAGGCTGCAGAATTTGAAGAAC
TGACCGGTATCAAGGTTAACTTTGAAGAGATAGCCTGGTCCAGCTGCATGGAGGTTATTTCAACTGCACTGGCAACCGGT
GAGGGCGCGAATGTAATGCAGGTTGGAACAACCCAGACACCTTTCTTTGCAGCTACCGGTGGATTGGTCGAAATAGACAT
TCGTGAATTTGGTGGAAAAGATAATTTTATGGAAGGCAATTTAAAGTCCACAGTACTGGATGGTAAGTACTATGGTGTAC
CGTGGATTGCAGAAACCAGAGTCCTGTTTTATAACACAGAAATGTTTGAAAAAGCAGGTGTTGAACCTCCCCAGACATGG
GAAGAACTTATTGAAGTTGGTGAAAAGATAGTTGATGTATATGGAGAGGGAACAGCTATTGCTATTGCTGGTACAAATGC
ATGGGACCTGATCCATAACTGGGCTCCGATGCTATGGACCAGGGGAGGAGATTTCCTGACACCAGACTGGAAACGGGCTG
CCTTTAACCTATCTGAAGCAGGGTATGAAGCAGTAGAATATTATGTAGACCTGGTAAGGAATGGTTTAGCAAGTACAGCA
TGTGCTGAATATGACCAGTCCCAGGCTGATTCAGCTTTTGCCAATGGTGATGTGGCAATGGCCTTCCAGGGACCATGGAA
TATTTCAGGTATAAAGAATGATAACCCCGATCTTCCATTTGCAGCTGCTGAACTTCCAGCTGGACCTTATGGTAGGGCTT
CCTTTGCCGGTGGTAGTAACCTCGTAGTCCGGAAAAATGCTCCACAGGATGAAATTGAAGCATCAATTAAGTGGATTAAA
TTCCTGTTAAGTGATACTAACCTGACAGAGTATGTTAAACTTTCTAACATGTTACCAGCAACCAAGGATGCATTTTCTGA
TCCATTCTTCCAGAGTGAGATAATGCAGGTATTTGAAAAATCATTGAGCTATGCACATGCTTATCCATCTTTACCTGCAT
GGGGTGAAATTGAACTGGCTATGAGGACCAGTTTTCAGAACATTCTTACCGATTATATTGATGGTGTATATGATGATAAT
ACCGCCAAAAAATACCTTGATGCTGCTGCATTAGAGGTAAACAACATATTAAAGGAACATAGTGATAAGTAA

Upstream 100 bases:

>100_bases
TACAGTGAAATTATTAGTTTACAGGGTTTAAGTAAGGAGAAGAGGTTTATCGGATGAAGGTTGGTCCAGGTATTTAAAAG
TAATGAGGAGGTTAATAATA

Downstream 100 bases:

>100_bases
TAAAACTGATAATAAAGGTGGACACACCCCATAATATCGAAGGGAAGGAGAATACCTCCTTCCCTCCCCCTATTTTATAT
TATAAAGTAATTGAGAGTAT

Product: family 1 extracellular solute-binding protein

Products: ADP; phosphate; maltose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 423; Mature: 423

Protein sequence:

>423_residues
MKKFFLLLVLTTLFVGTLAVSAGATEITMWAMNNAPSELNIAWFNEKAAEFEELTGIKVNFEEIAWSSCMEVISTALATG
EGANVMQVGTTQTPFFAATGGLVEIDIREFGGKDNFMEGNLKSTVLDGKYYGVPWIAETRVLFYNTEMFEKAGVEPPQTW
EELIEVGEKIVDVYGEGTAIAIAGTNAWDLIHNWAPMLWTRGGDFLTPDWKRAAFNLSEAGYEAVEYYVDLVRNGLASTA
CAEYDQSQADSAFANGDVAMAFQGPWNISGIKNDNPDLPFAAAELPAGPYGRASFAGGSNLVVRKNAPQDEIEASIKWIK
FLLSDTNLTEYVKLSNMLPATKDAFSDPFFQSEIMQVFEKSLSYAHAYPSLPAWGEIELAMRTSFQNILTDYIDGVYDDN
TAKKYLDAAALEVNNILKEHSDK

Sequences:

>Translated_423_residues
MKKFFLLLVLTTLFVGTLAVSAGATEITMWAMNNAPSELNIAWFNEKAAEFEELTGIKVNFEEIAWSSCMEVISTALATG
EGANVMQVGTTQTPFFAATGGLVEIDIREFGGKDNFMEGNLKSTVLDGKYYGVPWIAETRVLFYNTEMFEKAGVEPPQTW
EELIEVGEKIVDVYGEGTAIAIAGTNAWDLIHNWAPMLWTRGGDFLTPDWKRAAFNLSEAGYEAVEYYVDLVRNGLASTA
CAEYDQSQADSAFANGDVAMAFQGPWNISGIKNDNPDLPFAAAELPAGPYGRASFAGGSNLVVRKNAPQDEIEASIKWIK
FLLSDTNLTEYVKLSNMLPATKDAFSDPFFQSEIMQVFEKSLSYAHAYPSLPAWGEIELAMRTSFQNILTDYIDGVYDDN
TAKKYLDAAALEVNNILKEHSDK
>Mature_423_residues
MKKFFLLLVLTTLFVGTLAVSAGATEITMWAMNNAPSELNIAWFNEKAAEFEELTGIKVNFEEIAWSSCMEVISTALATG
EGANVMQVGTTQTPFFAATGGLVEIDIREFGGKDNFMEGNLKSTVLDGKYYGVPWIAETRVLFYNTEMFEKAGVEPPQTW
EELIEVGEKIVDVYGEGTAIAIAGTNAWDLIHNWAPMLWTRGGDFLTPDWKRAAFNLSEAGYEAVEYYVDLVRNGLASTA
CAEYDQSQADSAFANGDVAMAFQGPWNISGIKNDNPDLPFAAAELPAGPYGRASFAGGSNLVVRKNAPQDEIEASIKWIK
FLLSDTNLTEYVKLSNMLPATKDAFSDPFFQSEIMQVFEKSLSYAHAYPSLPAWGEIELAMRTSFQNILTDYIDGVYDDN
TAKKYLDAAALEVNNILKEHSDK

Specific function: Probably part of an ABC transporter complex [H]

COG id: COG1653

COG function: function code G; ABC-type sugar transport system, periplasmic component

Gene ontology:

Cell location: Periplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 1 family [H]

Homologues:

None

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 720 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 240 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase,

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006059
- InterPro:   IPR006061 [H]

Pfam domain/function: PF01547 SBP_bac_1 [H]

EC number: NA

Molecular weight: Translated: 46614; Mature: 46614

Theoretical pI: Translated: 4.10; Mature: 4.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKFFLLLVLTTLFVGTLAVSAGATEITMWAMNNAPSELNIAWFNEKAAEFEELTGIKVN
CCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCEEEEEECCHHHHHHHHCCCEEE
FEEIAWSSCMEVISTALATGEGANVMQVGTTQTPFFAATGGLVEIDIREFGGKDNFMEGN
HHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCEEECCCEEEEEHHHCCCCCCCCCCC
LKSTVLDGKYYGVPWIAETRVLFYNTEMFEKAGVEPPQTWEELIEVGEKIVDVYGEGTAI
CHHEEECCEECCCCCEECCEEEEEEHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCEEE
AIAGTNAWDLIHNWAPMLWTRGGDFLTPDWKRAAFNLSEAGYEAVEYYVDLVRNGLASTA
EEECCCHHHHHHCCHHHEEECCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHH
CAEYDQSQADSAFANGDVAMAFQGPWNISGIKNDNPDLPFAAAELPAGPYGRASFAGGSN
HHHHCHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCEEHHCCCCCCCCCCCCCCCCE
LVVRKNAPQDEIEASIKWIKFLLSDTNLTEYVKLSNMLPATKDAFSDPFFQSEIMQVFEK
EEEECCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHHH
SLSYAHAYPSLPAWGEIELAMRTSFQNILTDYIDGVYDDNTAKKYLDAAALEVNNILKEH
HHHHHHCCCCCCCCCCEEHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHC
SDK
CCC
>Mature Secondary Structure
MKKFFLLLVLTTLFVGTLAVSAGATEITMWAMNNAPSELNIAWFNEKAAEFEELTGIKVN
CCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCEEEEEECCHHHHHHHHCCCEEE
FEEIAWSSCMEVISTALATGEGANVMQVGTTQTPFFAATGGLVEIDIREFGGKDNFMEGN
HHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCEEECCCEEEEEHHHCCCCCCCCCCC
LKSTVLDGKYYGVPWIAETRVLFYNTEMFEKAGVEPPQTWEELIEVGEKIVDVYGEGTAI
CHHEEECCEECCCCCEECCEEEEEEHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCEEE
AIAGTNAWDLIHNWAPMLWTRGGDFLTPDWKRAAFNLSEAGYEAVEYYVDLVRNGLASTA
EEECCCHHHHHHCCHHHEEECCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHH
CAEYDQSQADSAFANGDVAMAFQGPWNISGIKNDNPDLPFAAAELPAGPYGRASFAGGSN
HHHHCHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCEEHHCCCCCCCCCCCCCCCCE
LVVRKNAPQDEIEASIKWIKFLLSDTNLTEYVKLSNMLPATKDAFSDPFFQSEIMQVFEK
EEEECCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHHH
SLSYAHAYPSLPAWGEIELAMRTSFQNILTDYIDGVYDDNTAKKYLDAAALEVNNILKEH
HHHHHHCCCCCCCCCCEEHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHC
SDK
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; maltose [Periplasm]; H2O [C]

Specific reaction: ATP + maltose [Periplasm] + H2O = ADP + phosphate + maltose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA