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The map label for this gene is pgsA [H]

Identifier: 220932033

GI number: 220932033

Start: 1290872

End: 1291429

Strand: Reverse

Name: pgsA [H]

Synonym: Hore_11960

Alternate gene names: 220932033

Gene position: 1291429-1290872 (Counterclockwise)

Preceding gene: 220932034

Following gene: 220932032

Centisome position: 50.09

GC content: 38.53

Gene sequence:

>558_bases
ATGAATTTGCCTAATAAATTAACATTGACCCGTATAATACTCGTACCTGTTTTTATGGGTTTTTTATTTCTCCGTAAGGA
CTACCCCGGTTATGCTGAAGTACTGGCCTTGATAACATTTGTTGTTGCAGCGGTTACCGATGGACTTGATGGATACCTGG
CCCGTAAACACAAAATTGTAACCAAATTTGGAAAGATTGTTGATCCTCTGGCCGATAAACTGTTAATATCAGCAGCCTTA
ATTTCATTTGTGGCTATGAAAGAAATTTCAGCCTGGGCTGCAATTATTATTATAGGCCGGGAACTGGCCATTACGGGCTT
AAGGGTAGTTGCTGCCAGTGAAGGTTCTGTTATTTCGGCCAGCTACTGGGGAAAATGGAAAACTACCCTACAGATTATTG
CAATAATAGCTTTGATCCTTGATCCTGAGATTATTCCACTTCCTTTTAATCTGTCCAGTATTCTCTTATGGGTTGCTGTA
ACCATTACGGTTATATCAGGAATTATGTACTTTAAAAATGCCGACATTGACTTTTTTAAAGAAGAAAAGGATGAATAA

Upstream 100 bases:

>100_bases
CAGGTTTATGTCTCCTGTAATGGAAAAATTAGTGAAGGTGACATGATTTTATGCAGGGTTACTGAGGCTTATGAATATGA
TTTACTGGGAGAGTGTATTT

Downstream 100 bases:

>100_bases
AGATATGTTCAGGATACTAAATAAAGTAATAGCAACAGGTTTTTTCTCAGGATATCTCCCTGTGGCCCCTGGAACCTGGG
GTTCATTACTGGCATTAATT

Product: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MNLPNKLTLTRIILVPVFMGFLFLRKDYPGYAEVLALITFVVAAVTDGLDGYLARKHKIVTKFGKIVDPLADKLLISAAL
ISFVAMKEISAWAAIIIIGRELAITGLRVVAASEGSVISASYWGKWKTTLQIIAIIALILDPEIIPLPFNLSSILLWVAV
TITVISGIMYFKNADIDFFKEEKDE

Sequences:

>Translated_185_residues
MNLPNKLTLTRIILVPVFMGFLFLRKDYPGYAEVLALITFVVAAVTDGLDGYLARKHKIVTKFGKIVDPLADKLLISAAL
ISFVAMKEISAWAAIIIIGRELAITGLRVVAASEGSVISASYWGKWKTTLQIIAIIALILDPEIIPLPFNLSSILLWVAV
TITVISGIMYFKNADIDFFKEEKDE
>Mature_185_residues
MNLPNKLTLTRIILVPVFMGFLFLRKDYPGYAEVLALITFVVAAVTDGLDGYLARKHKIVTKFGKIVDPLADKLLISAAL
ISFVAMKEISAWAAIIIIGRELAITGLRVVAASEGSVISASYWGKWKTTLQIIAIIALILDPEIIPLPFNLSSILLWVAV
TITVISGIMYFKNADIDFFKEEKDE

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=185, Percent_Identity=36.2162162162162, Blast_Score=93, Evalue=8e-21,
Organism=Saccharomyces cerevisiae, GI6320059, Length=211, Percent_Identity=31.2796208530806, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 20399; Mature: 20399

Theoretical pI: Translated: 8.82; Mature: 8.82

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLPNKLTLTRIILVPVFMGFLFLRKDYPGYAEVLALITFVVAAVTDGLDGYLARKHKIV
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
TKFGKIVDPLADKLLISAALISFVAMKEISAWAAIIIIGRELAITGLRVVAASEGSVISA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCHHHHHHEEEEEECCCCEEEE
SYWGKWKTTLQIIAIIALILDPEIIPLPFNLSSILLWVAVTITVISGIMYFKNADIDFFK
CCCCCHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
EEKDE
CCCCC
>Mature Secondary Structure
MNLPNKLTLTRIILVPVFMGFLFLRKDYPGYAEVLALITFVVAAVTDGLDGYLARKHKIV
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
TKFGKIVDPLADKLLISAALISFVAMKEISAWAAIIIIGRELAITGLRVVAASEGSVISA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCHHHHHHEEEEEECCCCEEEE
SYWGKWKTTLQIIAIIALILDPEIIPLPFNLSSILLWVAVTITVISGIMYFKNADIDFFK
CCCCCHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
EEKDE
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7750561; 9384377 [H]