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The map label for this gene is fumB [H]

Identifier: 220931849

GI number: 220931849

Start: 1096487

End: 1097035

Strand: Direct

Name: fumB [H]

Synonym: Hore_10060

Alternate gene names: 220931849

Gene position: 1096487-1097035 (Clockwise)

Preceding gene: 220931848

Following gene: 220931850

Centisome position: 42.53

GC content: 40.07

Gene sequence:

>549_bases
ATGATAAAAATTAAGACACCTTTATCTATTGATGATATTAAAAAATTAAAATCTGGTGACCGGGTCAGTCTTTCAGGTGT
TATTTATACAGCCCGTGATGCAGCCCATGCCAGGTTGGTAAAATTAATTAAGGAAAAAAAGCCACTTCCAGTACCTCTTG
AAGGTGAGGTAATATATTATGTTGGTCCTACCCCGGCTAAGCCGGGTAATCCCATTGGCTCTGCTGGACCAACTACCGGT
TATAGAATGGATCCATATGCCCCACTGTTAATGGAACAGGGGCTAAAGGGGATGATCGGCAAAGGGGCAAGATCACCTGA
AGTAAAGAGGTCAATGGTTAAGAATAAGGCTGTTTATTTTGCAGCGGTAGGTGGGGCAGCAGCTTTAATTTCAAAGTCAA
TCAAACATGCAGAAGTTATTGCCTATGATGACCTGGGTCCTGAAGCCATTCGCAGGCTTGAGGTTGAAAATTTACCCCTG
ATTGTTGTTAATGATATTTATGGTAATGACCTTTATGAAATAGGACGGAAAAAATATAAAAAAATATAA

Upstream 100 bases:

>100_bases
ATGTCATATTGCCTCTTTACCCGTTGGTATAAATATTAACTGCCATGCAGCCCGGCACAGAGAAATTATCCTTTAATATA
TACTTAAGTGGGGGATGAAC

Downstream 100 bases:

>100_bases
CAGGAGATGGTCTAAATGGATTTATATCGGGAAGCATTAAATATGCATAAACAGAAAACCGGTAAAATTAAAGTAGAGTG
TAAGGTGGATTTAAAAGATC

Product: fumarate hydratase subunit beta

Products: NA

Alternate protein names: Fumarase [H]

Number of amino acids: Translated: 182; Mature: 182

Protein sequence:

>182_residues
MIKIKTPLSIDDIKKLKSGDRVSLSGVIYTARDAAHARLVKLIKEKKPLPVPLEGEVIYYVGPTPAKPGNPIGSAGPTTG
YRMDPYAPLLMEQGLKGMIGKGARSPEVKRSMVKNKAVYFAAVGGAAALISKSIKHAEVIAYDDLGPEAIRRLEVENLPL
IVVNDIYGNDLYEIGRKKYKKI

Sequences:

>Translated_182_residues
MIKIKTPLSIDDIKKLKSGDRVSLSGVIYTARDAAHARLVKLIKEKKPLPVPLEGEVIYYVGPTPAKPGNPIGSAGPTTG
YRMDPYAPLLMEQGLKGMIGKGARSPEVKRSMVKNKAVYFAAVGGAAALISKSIKHAEVIAYDDLGPEAIRRLEVENLPL
IVVNDIYGNDLYEIGRKKYKKI
>Mature_182_residues
MIKIKTPLSIDDIKKLKSGDRVSLSGVIYTARDAAHARLVKLIKEKKPLPVPLEGEVIYYVGPTPAKPGNPIGSAGPTTG
YRMDPYAPLLMEQGLKGMIGKGARSPEVKRSMVKNKAVYFAAVGGAAALISKSIKHAEVIAYDDLGPEAIRRLEVENLPL
IVVNDIYGNDLYEIGRKKYKKI

Specific function: It functions in the generation of fumarate for use as an anaerobic electron acceptor [H]

COG id: COG1838

COG function: function code C; Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I fumarase family [H]

Homologues:

Organism=Escherichia coli, GI1790564, Length=155, Percent_Identity=44.5161290322581, Blast_Score=125, Evalue=1e-30,
Organism=Escherichia coli, GI1787897, Length=155, Percent_Identity=40, Blast_Score=110, Evalue=5e-26,
Organism=Escherichia coli, GI1789443, Length=181, Percent_Identity=33.1491712707182, Blast_Score=105, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004646
- InterPro:   IPR004647
- InterPro:   IPR011167
- InterPro:   IPR020557 [H]

Pfam domain/function: PF05681 Fumerase; PF05683 Fumerase_C [H]

EC number: =4.2.1.2 [H]

Molecular weight: Translated: 19800; Mature: 19800

Theoretical pI: Translated: 10.21; Mature: 10.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKIKTPLSIDDIKKLKSGDRVSLSGVIYTARDAAHARLVKLIKEKKPLPVPLEGEVIYY
CEEECCCCCHHHHHHHCCCCEEEEEEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCEEEE
VGPTPAKPGNPIGSAGPTTGYRMDPYAPLLMEQGLKGMIGKGARSPEVKRSMVKNKAVYF
ECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCHHHHCCCCCCHHHHHHHHHCCEEEE
AAVGGAAALISKSIKHAEVIAYDDLGPEAIRRLEVENLPLIVVNDIYGNDLYEIGRKKYK
EECCHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHH
KI
CC
>Mature Secondary Structure
MIKIKTPLSIDDIKKLKSGDRVSLSGVIYTARDAAHARLVKLIKEKKPLPVPLEGEVIYY
CEEECCCCCHHHHHHHCCCCEEEEEEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCEEEE
VGPTPAKPGNPIGSAGPTTGYRMDPYAPLLMEQGLKGMIGKGARSPEVKRSMVKNKAVYF
ECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCHHHHCCCCCCHHHHHHHHHCCEEEE
AAVGGAAALISKSIKHAEVIAYDDLGPEAIRRLEVENLPLIVVNDIYGNDLYEIGRKKYK
EECCHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHH
KI
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2656658; 7610040; 9278503 [H]