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The map label for this gene is ttdA [C]

Identifier: 220931848

GI number: 220931848

Start: 1095623

End: 1096462

Strand: Direct

Name: ttdA [C]

Synonym: Hore_10050

Alternate gene names: 220931848

Gene position: 1095623-1096462 (Clockwise)

Preceding gene: 220931847

Following gene: 220931849

Centisome position: 42.5

GC content: 38.81

Gene sequence:

>840_bases
ATGAGGACAATTGAGGCTGAAGAGATTACTAAAGTTGTAAAGGAAATGATAAAAGAAGCCAACTATTATCTTCCCGAAGA
TGTTTTAAGGTTTTTAAAAAATAATAAAGAAAAGGAAGAGTCATCCATTGGCAGGGATATTTTAAAACAGATAGTAAAGA
ATGCTCAAATAGCCTGTGAAGAAAAAATGCCTATCTGTCAGGATACTGGTCTTACCGTTGTTTTTCTTGAAATAGGAAAT
GAAGTTCACATTAATGGAGATATTTACAGGGCTGTTAATGAAGGGGTTAGACAGGGGTCACAGGAAGGTTATTTAAGGAA
ATCAGTTGTAAAAAGTCCCCTTAACAGGGTAAATACTGGAGATAATACACCGGCTGTTATCCATACTGAAATTGTACCCG
GGGATCGGTTAAAAATTATTATTGCTCCCAAGGGTGGTGGTAGTGAGAACATGAGCACGGTAAAAATGTTGAAACCTGCT
GATGGAATTGAAGGTATAAAAAAGACTGTATTAAAAACTGTTGAAGACGCTGGAGCCAATCCATGTCCTCCAATTATTGT
TGGGGTAGGACTCGGAGGGACCTTTGAAAAAGCCGCCCTTCTGGCTAAAAAAGCATTACTCCGTCCTTTAGATGATTCCC
ACCCTGATAAAGATGTTGCTGCTCTAGAAAATGACCTTTTAAATGAAATTAATAAACTCGGAATCGGTCCCCAGGGACTG
GGTGGAGTTACAACAGCTCTTTCTGTGAAAGTTGAAGTGTATCCATGTCATATTGCCTCTTTACCCGTTGGTATAAATAT
TAACTGCCATGCAGCCCGGCACAGAGAAATTATCCTTTAA

Upstream 100 bases:

>100_bases
ATAAACTATATTAAAAAATACGTAAAAAACATATGATATAACATATAGTAACCACGTGAACGATTTATATTGTTAAAATA
TATTTAAAAAGGGTGGTTGG

Downstream 100 bases:

>100_bases
TATATACTTAAGTGGGGGATGAACATGATAAAAATTAAGACACCTTTATCTATTGATGATATTAAAAAATTAAAATCTGG
TGACCGGGTCAGTCTTTCAG

Product: fumarate hydratase

Products: NA

Alternate protein names: Fumarase [H]

Number of amino acids: Translated: 279; Mature: 279

Protein sequence:

>279_residues
MRTIEAEEITKVVKEMIKEANYYLPEDVLRFLKNNKEKEESSIGRDILKQIVKNAQIACEEKMPICQDTGLTVVFLEIGN
EVHINGDIYRAVNEGVRQGSQEGYLRKSVVKSPLNRVNTGDNTPAVIHTEIVPGDRLKIIIAPKGGGSENMSTVKMLKPA
DGIEGIKKTVLKTVEDAGANPCPPIIVGVGLGGTFEKAALLAKKALLRPLDDSHPDKDVAALENDLLNEINKLGIGPQGL
GGVTTALSVKVEVYPCHIASLPVGININCHAARHREIIL

Sequences:

>Translated_279_residues
MRTIEAEEITKVVKEMIKEANYYLPEDVLRFLKNNKEKEESSIGRDILKQIVKNAQIACEEKMPICQDTGLTVVFLEIGN
EVHINGDIYRAVNEGVRQGSQEGYLRKSVVKSPLNRVNTGDNTPAVIHTEIVPGDRLKIIIAPKGGGSENMSTVKMLKPA
DGIEGIKKTVLKTVEDAGANPCPPIIVGVGLGGTFEKAALLAKKALLRPLDDSHPDKDVAALENDLLNEINKLGIGPQGL
GGVTTALSVKVEVYPCHIASLPVGININCHAARHREIIL
>Mature_279_residues
MRTIEAEEITKVVKEMIKEANYYLPEDVLRFLKNNKEKEESSIGRDILKQIVKNAQIACEEKMPICQDTGLTVVFLEIGN
EVHINGDIYRAVNEGVRQGSQEGYLRKSVVKSPLNRVNTGDNTPAVIHTEIVPGDRLKIIIAPKGGGSENMSTVKMLKPA
DGIEGIKKTVLKTVEDAGANPCPPIIVGVGLGGTFEKAALLAKKALLRPLDDSHPDKDVAALENDLLNEINKLGIGPQGL
GGVTTALSVKVEVYPCHIASLPVGININCHAARHREIIL

Specific function: Unknown

COG id: COG1951

COG function: function code C; Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I fumarase family [H]

Homologues:

Organism=Escherichia coli, GI1789442, Length=276, Percent_Identity=32.9710144927536, Blast_Score=155, Evalue=2e-39,
Organism=Escherichia coli, GI1790564, Length=287, Percent_Identity=29.9651567944251, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1787897, Length=297, Percent_Identity=30.6397306397306, Blast_Score=103, Evalue=9e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004646 [H]

Pfam domain/function: PF05681 Fumerase [H]

EC number: =4.2.1.2 [H]

Molecular weight: Translated: 30220; Mature: 30220

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS00659 GLYCOSYL_HYDROL_F5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTIEAEEITKVVKEMIKEANYYLPEDVLRFLKNNKEKEESSIGRDILKQIVKNAQIACE
CCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCEEHH
EKMPICQDTGLTVVFLEIGNEVHINGDIYRAVNEGVRQGSQEGYLRKSVVKSPLNRVNTG
CCCCCCCCCCCEEEEEEECCEEEECCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCC
DNTPAVIHTEIVPGDRLKIIIAPKGGGSENMSTVKMLKPADGIEGIKKTVLKTVEDAGAN
CCCCEEEEEEECCCCCEEEEEEECCCCCCCCCHHEEECCCCHHHHHHHHHHHHHHHCCCC
PCPPIIVGVGLGGTFEKAALLAKKALLRPLDDSHPDKDVAALENDLLNEINKLGIGPQGL
CCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCC
GGVTTALSVKVEVYPCHIASLPVGININCHAARHREIIL
CCCEEEEEEEEEEEEEEEECCCEEEEEEECCCCCCCCCC
>Mature Secondary Structure
MRTIEAEEITKVVKEMIKEANYYLPEDVLRFLKNNKEKEESSIGRDILKQIVKNAQIACE
CCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCEEHH
EKMPICQDTGLTVVFLEIGNEVHINGDIYRAVNEGVRQGSQEGYLRKSVVKSPLNRVNTG
CCCCCCCCCCCEEEEEEECCEEEECCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCC
DNTPAVIHTEIVPGDRLKIIIAPKGGGSENMSTVKMLKPADGIEGIKKTVLKTVEDAGAN
CCCCEEEEEEECCCCCEEEEEEECCCCCCCCCHHEEECCCCHHHHHHHHHHHHHHHCCCC
PCPPIIVGVGLGGTFEKAALLAKKALLRPLDDSHPDKDVAALENDLLNEINKLGIGPQGL
CCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCC
GGVTTALSVKVEVYPCHIASLPVGININCHAARHREIIL
CCCEEEEEEEEEEEEEEEECCCEEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]