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The map label for this gene is rsmB [H]

Identifier: 220931836

GI number: 220931836

Start: 1083157

End: 1084479

Strand: Direct

Name: rsmB [H]

Synonym: Hore_09930

Alternate gene names: 220931836

Gene position: 1083157-1084479 (Clockwise)

Preceding gene: 220931835

Following gene: 220931837

Centisome position: 42.01

GC content: 37.57

Gene sequence:

>1323_bases
ATGTCAATATCAAGAAAAGTAGCAATTAAGGTATTAATTGAGATTGATAAAGGGGCATATTCAAATTTAGTTTTGAATAA
AGAATTAAATAAGGTTTCAGATAAAAGAGATAGGGCCTTTATTACAGAATTAGTATATGGAGTTTTAAGACAAAAAAAAC
GACTGGATTATATGCTATCCTGTTTTTCAAAACGCCCCCTGAGAAAAATGGATAATGAAGTATTATCAGCTTTAAGGGTC
GCGCTGTACCAGATCGAATACACCGATAGTGTACCAGCCCGGGCTGCAGTTTATGAAACAGTTGAAGCCCTCAAGTCTTT
TACCGGACATGGTGCTGTTAAATTTACAAATGGGGTTTTGAGGTCTTATCTCAGGAATAAAGATAAAATAATCTTTCCTG
ACCGGAATCAAAACCCGGTAAACTTTTTAGCAAACTATTATTCTTATCCAGAATGGATAATTAAAGAATGGATTAATAAA
TACGGGTTTAAAGATACAGAAAGGTTATGCCAGTATCTGAATGATTCACCACCGGTTACGGTACGGTACAATCGGTTACA
GGTAGATCAAAAACGTTTTCTTGAAGTTTTTAAAAAATATAATATAGAGGTTGAAAGTACTACTGTTCCTGATTGTTATG
TTGTTAACAATTTTAATACTATTAAAGACCTGCCTTTATTTAAGGATGGAGGTTTTATAGTCCAGGGGCCTGCTGCAACC
CTGGCAGGTTTTGTTTTGGGCCCGGACCCCGGGAACAGGGTACTGGATATGTCTGCAGGCCCGGGTGGAAAGACAACCCA
TCTGGCAGAGTTAATGAATAATCGGGGAGAGATTATAGCCCTTGATATATATGAACATAAGTTAAAGTTAATCGAGGAAA
ACTGTAACAGACTCGGTGTTAATATTGTAAAGACAATAAAGGTTGATGGTCGTGATTACACCAGTCAAGAAAAATTTGAT
ATGGTTTTAGTGGATGCCCCCTGTACCGGCCTTGGGCTTGTTGCCCATAAACCAGAAATAAAGTGGAATAGAACAGAGAA
TGATGTAAAAAAACTTCAGGAAATACAGAAGAGTCTTTTGCATAATGCTTTATCTCTGGTCAGGGATGGGGGATTTGTAC
TGTACAGTACATGTACTCTTACCCGTGCTGAAAATGAAGAAGTTGTTAATCAGGTATTACAGCAGACTGATTTTGTAGTA
TCCCCTGTTAATATGGAAAAAAGGCTGTCTGAAATAGGGTTTTCAGGTAAATTTAAAATAACCCCGGAGGGTTACCTGGA
GTTCTTCCCCCCTGAAAGTAAGACCGAAGGTTTTTATGGCTAA

Upstream 100 bases:

>100_bases
ACCAGCCCGTTAAAATATTTGTCCATACCCGACAGATACCGTATATTAATTAAATTTTTAGTTTATAAATATAATAAGGG
TTATGTTAGGAGATATTTTT

Downstream 100 bases:

>100_bases
ATTACAAAAATATGGAGGAAATTATTGATGGAGACAAAAGAGGATTTGAAGTCATTAAGTAGAAAAGAGTTATTAATGTG
GTTTGAAAAGAGGGGATATC

Product: sun protein

Products: NA

Alternate protein names: rRNA (cytosine-C(5)-)-methyltransferase rsmB [H]

Number of amino acids: Translated: 440; Mature: 439

Protein sequence:

>440_residues
MSISRKVAIKVLIEIDKGAYSNLVLNKELNKVSDKRDRAFITELVYGVLRQKKRLDYMLSCFSKRPLRKMDNEVLSALRV
ALYQIEYTDSVPARAAVYETVEALKSFTGHGAVKFTNGVLRSYLRNKDKIIFPDRNQNPVNFLANYYSYPEWIIKEWINK
YGFKDTERLCQYLNDSPPVTVRYNRLQVDQKRFLEVFKKYNIEVESTTVPDCYVVNNFNTIKDLPLFKDGGFIVQGPAAT
LAGFVLGPDPGNRVLDMSAGPGGKTTHLAELMNNRGEIIALDIYEHKLKLIEENCNRLGVNIVKTIKVDGRDYTSQEKFD
MVLVDAPCTGLGLVAHKPEIKWNRTENDVKKLQEIQKSLLHNALSLVRDGGFVLYSTCTLTRAENEEVVNQVLQQTDFVV
SPVNMEKRLSEIGFSGKFKITPEGYLEFFPPESKTEGFYG

Sequences:

>Translated_440_residues
MSISRKVAIKVLIEIDKGAYSNLVLNKELNKVSDKRDRAFITELVYGVLRQKKRLDYMLSCFSKRPLRKMDNEVLSALRV
ALYQIEYTDSVPARAAVYETVEALKSFTGHGAVKFTNGVLRSYLRNKDKIIFPDRNQNPVNFLANYYSYPEWIIKEWINK
YGFKDTERLCQYLNDSPPVTVRYNRLQVDQKRFLEVFKKYNIEVESTTVPDCYVVNNFNTIKDLPLFKDGGFIVQGPAAT
LAGFVLGPDPGNRVLDMSAGPGGKTTHLAELMNNRGEIIALDIYEHKLKLIEENCNRLGVNIVKTIKVDGRDYTSQEKFD
MVLVDAPCTGLGLVAHKPEIKWNRTENDVKKLQEIQKSLLHNALSLVRDGGFVLYSTCTLTRAENEEVVNQVLQQTDFVV
SPVNMEKRLSEIGFSGKFKITPEGYLEFFPPESKTEGFYG
>Mature_439_residues
SISRKVAIKVLIEIDKGAYSNLVLNKELNKVSDKRDRAFITELVYGVLRQKKRLDYMLSCFSKRPLRKMDNEVLSALRVA
LYQIEYTDSVPARAAVYETVEALKSFTGHGAVKFTNGVLRSYLRNKDKIIFPDRNQNPVNFLANYYSYPEWIIKEWINKY
GFKDTERLCQYLNDSPPVTVRYNRLQVDQKRFLEVFKKYNIEVESTTVPDCYVVNNFNTIKDLPLFKDGGFIVQGPAATL
AGFVLGPDPGNRVLDMSAGPGGKTTHLAELMNNRGEIIALDIYEHKLKLIEENCNRLGVNIVKTIKVDGRDYTSQEKFDM
VLVDAPCTGLGLVAHKPEIKWNRTENDVKKLQEIQKSLLHNALSLVRDGGFVLYSTCTLTRAENEEVVNQVLQQTDFVVS
PVNMEKRLSEIGFSGKFKITPEGYLEFFPPESKTEGFYG

Specific function: Unknown

COG id: COG0144

COG function: function code J; tRNA and rRNA cytosine-C5-methylases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmB/NOP family [H]

Homologues:

Organism=Homo sapiens, GI76150625, Length=312, Percent_Identity=29.8076923076923, Blast_Score=143, Evalue=3e-34,
Organism=Homo sapiens, GI76150623, Length=312, Percent_Identity=29.8076923076923, Blast_Score=143, Evalue=3e-34,
Organism=Homo sapiens, GI32698918, Length=195, Percent_Identity=35.3846153846154, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI8922322, Length=196, Percent_Identity=32.1428571428571, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI23199998, Length=196, Percent_Identity=32.1428571428571, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI270288816, Length=196, Percent_Identity=32.1428571428571, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI270288818, Length=196, Percent_Identity=32.1428571428571, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI11545785, Length=156, Percent_Identity=32.6923076923077, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI40316918, Length=168, Percent_Identity=32.7380952380952, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI39995082, Length=189, Percent_Identity=25.3968253968254, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI301336155, Length=189, Percent_Identity=25.3968253968254, Blast_Score=66, Evalue=5e-11,
Organism=Escherichia coli, GI2367212, Length=387, Percent_Identity=30.2325581395349, Blast_Score=192, Evalue=4e-50,
Organism=Escherichia coli, GI87081985, Length=275, Percent_Identity=31.6363636363636, Blast_Score=120, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17536757, Length=316, Percent_Identity=29.1139240506329, Blast_Score=139, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI71998419, Length=216, Percent_Identity=32.4074074074074, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI115534021, Length=216, Percent_Identity=32.4074074074074, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI25143471, Length=196, Percent_Identity=27.5510204081633, Blast_Score=73, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6324268, Length=261, Percent_Identity=27.2030651340996, Blast_Score=124, Evalue=4e-29,
Organism=Saccharomyces cerevisiae, GI6319447, Length=200, Percent_Identity=29.5, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6324306, Length=275, Percent_Identity=24.3636363636364, Blast_Score=68, Evalue=3e-12,
Organism=Drosophila melanogaster, GI22024126, Length=273, Percent_Identity=30.4029304029304, Blast_Score=128, Evalue=6e-30,
Organism=Drosophila melanogaster, GI24668781, Length=197, Percent_Identity=32.994923857868, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI21356513, Length=197, Percent_Identity=32.994923857868, Blast_Score=102, Evalue=6e-22,
Organism=Drosophila melanogaster, GI21356579, Length=172, Percent_Identity=33.1395348837209, Blast_Score=95, Evalue=8e-20,
Organism=Drosophila melanogaster, GI19920494, Length=175, Percent_Identity=32.5714285714286, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21355201, Length=199, Percent_Identity=29.1457286432161, Blast_Score=79, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001678
- InterPro:   IPR018314
- InterPro:   IPR006027
- InterPro:   IPR004573 [H]

Pfam domain/function: PF01189 Nol1_Nop2_Fmu; PF01029 NusB [H]

EC number: NA

Molecular weight: Translated: 50164; Mature: 50033

Theoretical pI: Translated: 8.81; Mature: 8.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSISRKVAIKVLIEIDKGAYSNLVLNKELNKVSDKRDRAFITELVYGVLRQKKRLDYMLS
CCCCCEEEEEEEEEECCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CFSKRPLRKMDNEVLSALRVALYQIEYTDSVPARAAVYETVEALKSFTGHGAVKFTNGVL
HHCCCCHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHCCCCCEEEHHHHH
RSYLRNKDKIIFPDRNQNPVNFLANYYSYPEWIIKEWINKYGFKDTERLCQYLNDSPPVT
HHHHCCCCCEEECCCCCCHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHCCCCCEE
VRYNRLQVDQKRFLEVFKKYNIEVESTTVPDCYVVNNFNTIKDLPLFKDGGFIVQGPAAT
EEEEEECCCHHHHHHHHHHHCCEEECCCCCCEEEECCCCCHHCCCEEECCCEEEECCHHH
LAGFVLGPDPGNRVLDMSAGPGGKTTHLAELMNNRGEIIALDIYEHKLKLIEENCNRLGV
HEEEEECCCCCCEEEEECCCCCCCHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHCCC
NIVKTIKVDGRDYTSQEKFDMVLVDAPCTGLGLVAHKPEIKWNRTENDVKKLQEIQKSLL
EEEEEEEECCCCCCCCCCCCEEEEECCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHH
HNALSLVRDGGFVLYSTCTLTRAENEEVVNQVLQQTDFVVSPVNMEKRLSEIGFSGKFKI
HHHHHHHHCCCEEEEEEEEEECCCCHHHHHHHHHHCCCEECCCCHHHHHHHCCCCCEEEE
TPEGYLEFFPPESKTEGFYG
CCCCCEEECCCCCCCCCCCC
>Mature Secondary Structure 
SISRKVAIKVLIEIDKGAYSNLVLNKELNKVSDKRDRAFITELVYGVLRQKKRLDYMLS
CCCCEEEEEEEEEECCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CFSKRPLRKMDNEVLSALRVALYQIEYTDSVPARAAVYETVEALKSFTGHGAVKFTNGVL
HHCCCCHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHCCCCCEEEHHHHH
RSYLRNKDKIIFPDRNQNPVNFLANYYSYPEWIIKEWINKYGFKDTERLCQYLNDSPPVT
HHHHCCCCCEEECCCCCCHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHCCCCCEE
VRYNRLQVDQKRFLEVFKKYNIEVESTTVPDCYVVNNFNTIKDLPLFKDGGFIVQGPAAT
EEEEEECCCHHHHHHHHHHHCCEEECCCCCCEEEECCCCCHHCCCEEECCCEEEECCHHH
LAGFVLGPDPGNRVLDMSAGPGGKTTHLAELMNNRGEIIALDIYEHKLKLIEENCNRLGV
HEEEEECCCCCCEEEEECCCCCCCHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHCCC
NIVKTIKVDGRDYTSQEKFDMVLVDAPCTGLGLVAHKPEIKWNRTENDVKKLQEIQKSLL
EEEEEEEECCCCCCCCCCCCEEEEECCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHH
HNALSLVRDGGFVLYSTCTLTRAENEEVVNQVLQQTDFVVSPVNMEKRLSEIGFSGKFKI
HHHHHHHHCCCEEEEEEEEEECCCCHHHHHHHHHHCCCEECCCCHHHHHHHCCCCCEEEE
TPEGYLEFFPPESKTEGFYG
CCCCCEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377; 9086272 [H]