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The map label for this gene is fucA [H]

Identifier: 220931804

GI number: 220931804

Start: 1039405

End: 1040049

Strand: Direct

Name: fucA [H]

Synonym: Hore_09610

Alternate gene names: 220931804

Gene position: 1039405-1040049 (Clockwise)

Preceding gene: 220931803

Following gene: 220931805

Centisome position: 40.32

GC content: 32.87

Gene sequence:

>645_bases
TTGCTTTTAGAAAAAGAACGAAAACAGATAGTTGAATATGGCAAGAAATTAATAGATTCAGGTTTGACCAGGGGAACAGG
AGGAAATATAAGTATATTTAATTTTGAAAAAAAGTTAATGGCAATTAGTCCAACAGGTATAGAATATTTTGATACTTCTC
CGGAAGATGTCGTAGTTATGAACTTAAATGGGAAAATTGTAGAAGGAAGCAAAAAGCCTTCCAGTGAATACAGGATGCAT
CTTATTTTTTATAAAAATCGAAATGATGTTGGTGCTGTAGTACATACTCATTCTATTTATGCAGCAACAATAGCATCTTT
AAGATGGGAATTGCCTCCTGTTCATTATATGATTGCAGTTGCTGGTAATAAAGTACCCTGTGCAGAATATGCTAGTTTTG
GAACAGAAGAATTAGCTACCAATGCGTTTAAAAGTGTGGGAGAAACATATAACGCTACATTATTGGCTAATCATGGTTTA
ATAGCTTTGGGTAAAAATATCTCTGAAGCATTTAAAGTAGCAGAAGAGATTGAGTTTACAGCTGAAGTTTATTATAGAGC
TAAAGCTATTGGGGAGCCTGTAATTTTACCAGAGGAAGAAATGAAAGTTATGTTAAATAAATTTAAAACGTATGGTCAAC
AATGA

Upstream 100 bases:

>100_bases
GAGAAATTAAAAATTTAAAAGAAGGTCGAGAAATAATTAAAAATTCAGTTGAATTAAAACATTATAACCCTTAATTAAAA
TCAGATAGGTGGTGTGTAAA

Downstream 100 bases:

>100_bases
ATATCATATGTTGACAAATAATTTATTAATGATACTAAAGTTCGACAAATAAAAACACAATATCCCAATCTCTGTCACCA
ACAAGTTAAACCGGTCATAT

Product: class II aldolase/adducin family protein

Products: NA

Alternate protein names: L-fuculose-1-phosphate aldolase [H]

Number of amino acids: Translated: 214; Mature: 214

Protein sequence:

>214_residues
MLLEKERKQIVEYGKKLIDSGLTRGTGGNISIFNFEKKLMAISPTGIEYFDTSPEDVVVMNLNGKIVEGSKKPSSEYRMH
LIFYKNRNDVGAVVHTHSIYAATIASLRWELPPVHYMIAVAGNKVPCAEYASFGTEELATNAFKSVGETYNATLLANHGL
IALGKNISEAFKVAEEIEFTAEVYYRAKAIGEPVILPEEEMKVMLNKFKTYGQQ

Sequences:

>Translated_214_residues
MLLEKERKQIVEYGKKLIDSGLTRGTGGNISIFNFEKKLMAISPTGIEYFDTSPEDVVVMNLNGKIVEGSKKPSSEYRMH
LIFYKNRNDVGAVVHTHSIYAATIASLRWELPPVHYMIAVAGNKVPCAEYASFGTEELATNAFKSVGETYNATLLANHGL
IALGKNISEAFKVAEEIEFTAEVYYRAKAIGEPVILPEEEMKVMLNKFKTYGQQ
>Mature_214_residues
MLLEKERKQIVEYGKKLIDSGLTRGTGGNISIFNFEKKLMAISPTGIEYFDTSPEDVVVMNLNGKIVEGSKKPSSEYRMH
LIFYKNRNDVGAVVHTHSIYAATIASLRWELPPVHYMIAVAGNKVPCAEYASFGTEELATNAFKSVGETYNATLLANHGL
IALGKNISEAFKVAEEIEFTAEVYYRAKAIGEPVILPEEEMKVMLNKFKTYGQQ

Specific function: Fucose metabolism; third step. [C]

COG id: COG0235

COG function: function code G; Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldolase class II family. AraD/FucA subfamily [H]

Homologues:

Organism=Homo sapiens, GI297307160, Length=160, Percent_Identity=26.875, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI89276787, Length=156, Percent_Identity=26.2820512820513, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI9257190, Length=172, Percent_Identity=25.5813953488372, Blast_Score=65, Evalue=3e-11,
Organism=Homo sapiens, GI297307158, Length=172, Percent_Identity=25.5813953488372, Blast_Score=64, Evalue=7e-11,
Organism=Homo sapiens, GI9257192, Length=172, Percent_Identity=25.5813953488372, Blast_Score=64, Evalue=7e-11,
Organism=Escherichia coli, GI1789164, Length=210, Percent_Identity=42.3809523809524, Blast_Score=162, Evalue=2e-41,
Organism=Escherichia coli, GI1790008, Length=195, Percent_Identity=31.2820512820513, Blast_Score=84, Evalue=5e-18,
Organism=Escherichia coli, GI1790642, Length=201, Percent_Identity=30.3482587064677, Blast_Score=84, Evalue=5e-18,
Organism=Escherichia coli, GI1786247, Length=196, Percent_Identity=29.0816326530612, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI1789094, Length=185, Percent_Identity=28.6486486486486, Blast_Score=77, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001303
- InterPro:   IPR004782 [H]

Pfam domain/function: PF00596 Aldolase_II [H]

EC number: =4.1.2.17 [H]

Molecular weight: Translated: 23836; Mature: 23836

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLEKERKQIVEYGKKLIDSGLTRGTGGNISIFNFEKKLMAISPTGIEYFDTSPEDVVVM
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCEEEEECCCCCEECCCCCCCEEEE
NLNGKIVEGSKKPSSEYRMHLIFYKNRNDVGAVVHTHSIYAATIASLRWELPPVHYMIAV
ECCCEEEECCCCCCCCEEEEEEEEECCCCCEEEEEEHHHHHHHHHHHHCCCCCEEEEEEE
AGNKVPCAEYASFGTEELATNAFKSVGETYNATLLANHGLIALGKNISEAFKVAEEIEFT
CCCCCCHHHHHHCCHHHHHHHHHHHHCCCCCEEEEECCCEEEECCCHHHHHHHHHHHHHH
AEVYYRAKAIGEPVILPEEEMKVMLNKFKTYGQQ
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLLEKERKQIVEYGKKLIDSGLTRGTGGNISIFNFEKKLMAISPTGIEYFDTSPEDVVVM
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCEEEEECCCCCEECCCCCCCEEEE
NLNGKIVEGSKKPSSEYRMHLIFYKNRNDVGAVVHTHSIYAATIASLRWELPPVHYMIAV
ECCCEEEECCCCCCCCEEEEEEEEECCCCCEEEEEEHHHHHHHHHHHHCCCCCEEEEEEE
AGNKVPCAEYASFGTEELATNAFKSVGETYNATLLANHGLIALGKNISEAFKVAEEIEFT
CCCCCCHHHHHHCCHHHHHHHHHHHHCCCCCEEEEECCCEEEECCCHHHHHHHHHHHHHH
AEVYYRAKAIGEPVILPEEEMKVMLNKFKTYGQQ
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]