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The map label for this gene is mraY [H]

Identifier: 220931749

GI number: 220931749

Start: 978873

End: 979838

Strand: Direct

Name: mraY [H]

Synonym: Hore_09060

Alternate gene names: 220931749

Gene position: 978873-979838 (Clockwise)

Preceding gene: 220931748

Following gene: 220931750

Centisome position: 37.97

GC content: 39.44

Gene sequence:

>966_bases
ATGGAATATTTTGTAGCCCTGTGTGTGCCGTTTTTAATATTGATGATATTTGGACGGGGGTTAATCAAATTACTAAAAAT
ATTAAATTTTGGTCAACAGGTCAGAAATGAAGGTCCAAAATCCCATTTAAACAAAGAAGGAATACCTACCATGGGCGGGG
TTTTAATAATACTGGCTATTCTGGTTACTTCCTTAATCTTTGTTGATTTAAAGACCCCGGTTATCTGGGCCCTCATTACT
ACAACCGGTATGGGACTGGTCGGTTTTTTTGATGATATTATTAAAGTAAGGACCAGGAGGTCACTGGGGTTAAGGGCAAG
AGAAAAGCTGGCCGGACAGGTTTTGTTTGGCCTGCTGCTGGCCTTATATGTTTATTATTATTCAGATATAGGTTCAACAC
TTATTATACCCGTTTCAGGACAAGTTATCGACCTTGGCTATGTTATTATTCCCTTTATTATTGTGGTCGTTATCGGGACT
GCTAATGCTGTAAATTTAACTGATGGACTGGATGGACTGGCTGCTGGAGTTACCCTGATTGTAGCCAGTGCTTTTGCAGT
TATTACATCTGGTCTGGGTTTGCAGGGTTTAACCTGTTATTCCCTTATTATAAGTGGGGCCTGTCTCGGTTTTATCTGGT
ATAATAGTCATCCAGCCCAGGTTTTTATGGGGGATGTGGGTTCACTGGCCCTTGGTGGAGCTATTGCTTCCATAGCAGTT
CTTTCCAGAACCGAGTTGTTTTTACTGATCATAGGAGCTGTTTATGTTGTTGAAACCCTGTCAGTTATAATACAGGTTAT
CTACTTTCGGTTAACAGGTGGTAAAAGAGTTTTTAAAATGACTCCAATTCATCATCATTTTGAGTTAAGTGGTCTGGCTG
AGTCAAAGGTTGTAGCCAGATTCTGGATAATAAGTCTTATATTTGCTGTACTCGGAATTATATCTTTTTATCTTATCGGT
AGTTAA

Upstream 100 bases:

>100_bases
GATTTAATAAAAAAAGGTGATACAATTTTGGTTAAGGGTTCAAGAGGAAACAAAATGGAAGAAATAGTTAAGATGGTCAG
TTCACAGGAGGATTAAAACT

Downstream 100 bases:

>100_bases
CTTAAGGTTTTTTATAATTGATTTTATCCTTGCAAAAATGTTTGAGTAAAAAGGAGTAGACTTTCCATGATAGATGTAAG
TAGCAAAAAAGTTGCCGTTA

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase [H]

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MEYFVALCVPFLILMIFGRGLIKLLKILNFGQQVRNEGPKSHLNKEGIPTMGGVLIILAILVTSLIFVDLKTPVIWALIT
TTGMGLVGFFDDIIKVRTRRSLGLRAREKLAGQVLFGLLLALYVYYYSDIGSTLIIPVSGQVIDLGYVIIPFIIVVVIGT
ANAVNLTDGLDGLAAGVTLIVASAFAVITSGLGLQGLTCYSLIISGACLGFIWYNSHPAQVFMGDVGSLALGGAIASIAV
LSRTELFLLIIGAVYVVETLSVIIQVIYFRLTGGKRVFKMTPIHHHFELSGLAESKVVARFWIISLIFAVLGIISFYLIG
S

Sequences:

>Translated_321_residues
MEYFVALCVPFLILMIFGRGLIKLLKILNFGQQVRNEGPKSHLNKEGIPTMGGVLIILAILVTSLIFVDLKTPVIWALIT
TTGMGLVGFFDDIIKVRTRRSLGLRAREKLAGQVLFGLLLALYVYYYSDIGSTLIIPVSGQVIDLGYVIIPFIIVVVIGT
ANAVNLTDGLDGLAAGVTLIVASAFAVITSGLGLQGLTCYSLIISGACLGFIWYNSHPAQVFMGDVGSLALGGAIASIAV
LSRTELFLLIIGAVYVVETLSVIIQVIYFRLTGGKRVFKMTPIHHHFELSGLAESKVVARFWIISLIFAVLGIISFYLIG
S
>Mature_321_residues
MEYFVALCVPFLILMIFGRGLIKLLKILNFGQQVRNEGPKSHLNKEGIPTMGGVLIILAILVTSLIFVDLKTPVIWALIT
TTGMGLVGFFDDIIKVRTRRSLGLRAREKLAGQVLFGLLLALYVYYYSDIGSTLIIPVSGQVIDLGYVIIPFIIVVVIGT
ANAVNLTDGLDGLAAGVTLIVASAFAVITSGLGLQGLTCYSLIISGACLGFIWYNSHPAQVFMGDVGSLALGGAIASIAV
LSRTELFLLIIGAVYVVETLSVIIQVIYFRLTGGKRVFKMTPIHHHFELSGLAESKVVARFWIISLIFAVLGIISFYLIG
S

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan [H]

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786275, Length=330, Percent_Identity=43.6363636363636, Blast_Score=245, Evalue=3e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4 [H]

EC number: =2.7.8.13 [H]

Molecular weight: Translated: 34584; Mature: 34584

Theoretical pI: Translated: 9.25; Mature: 9.25

Prosite motif: PS01347 MRAY_1 ; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYFVALCVPFLILMIFGRGLIKLLKILNFGQQVRNEGPKSHLNKEGIPTMGGVLIILAI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCHHHHHHHHHH
LVTSLIFVDLKTPVIWALITTTGMGLVGFFDDIIKVRTRRSLGLRAREKLAGQVLFGLLL
HHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHH
ALYVYYYSDIGSTLIIPVSGQVIDLGYVIIPFIIVVVIGTANAVNLTDGLDGLAAGVTLI
HHHHHHHHHCCCEEEEECCCCEEHHHHHHHHHHHHHHHCCCCCEECCCCHHHHHHHHHHH
VASAFAVITSGLGLQGLTCYSLIISGACLGFIWYNSHPAQVFMGDVGSLALGGAIASIAV
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHEEEEECCCCCEEEECCHHHHHHHHHHHHHHH
LSRTELFLLIIGAVYVVETLSVIIQVIYFRLTGGKRVFKMTPIHHHFELSGLAESKVVAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHCCCHHHHHHHH
FWIISLIFAVLGIISFYLIGS
HHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MEYFVALCVPFLILMIFGRGLIKLLKILNFGQQVRNEGPKSHLNKEGIPTMGGVLIILAI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCHHHHHHHHHH
LVTSLIFVDLKTPVIWALITTTGMGLVGFFDDIIKVRTRRSLGLRAREKLAGQVLFGLLL
HHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHH
ALYVYYYSDIGSTLIIPVSGQVIDLGYVIIPFIIVVVIGTANAVNLTDGLDGLAAGVTLI
HHHHHHHHHCCCEEEEECCCCEEHHHHHHHHHHHHHHHCCCCCEECCCCHHHHHHHHHHH
VASAFAVITSGLGLQGLTCYSLIISGACLGFIWYNSHPAQVFMGDVGSLALGGAIASIAV
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHEEEEECCCCCEEEECCHHHHHHHHHHHHHHH
LSRTELFLLIIGAVYVVETLSVIIQVIYFRLTGGKRVFKMTPIHHHFELSGLAESKVVAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHCCCHHHHHHHH
FWIISLIFAVLGIISFYLIGS
HHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA