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The map label for this gene is yqiR [H]

Identifier: 220931516

GI number: 220931516

Start: 728887

End: 730632

Strand: Direct

Name: yqiR [H]

Synonym: Hore_06720

Alternate gene names: 220931516

Gene position: 728887-730632 (Clockwise)

Preceding gene: 220931515

Following gene: 220931517

Centisome position: 28.27

GC content: 38.77

Gene sequence:

>1746_bases
ATGTCTGAAAAGGTTAATTTTAAACAATTAAGTGAATTAAACCGGAAGACAGATGTTATATTAAATTCAACTCATGATGG
CCTTATATCTATTGGAAAAGATTATAAAGTTGAGCTCTTTAATAGAGCAGCTGAAAAAATACTGGGTATTAAAAAAGATA
GAGTTCTTGGCAAAGATGTAAGAGAAGTAATTCCTAACACAAGGCTTCATATTGTTCTTAATAAGGGTGAGGCGGAACTA
AATAAAATTCAACATGCCGGTGATATTACTATTATTACTAACCGGGTTCCTGTATATGATGAACAGGGAAATATAATTGG
GGCGGTAGCTGTTTTCAGGGATATTACTGAAGTCAAAAAACTGGCAGAAGAAATTACCAATTTGAAAGAGATGAGGACCC
TACTGGAAGCTATAATAAATGCTACTCAGGATGCTATTTCAGTAGTTGATGAAAAAGGAATAGGAATATTGATTAATCCA
GCCTATACCCGTTTGACCGGTTTGACAGAGGAAGATGTTATTGGTAAACCGGCTACTGTGGATATAGCTGAAGGGGAGAG
TATGCACTACCGTGTTTTAAAGACCAAAAAACCGGTAAAAGGGGTAAAGATGAAAGTTGGTCCATCAAAGAAAGAAGTCA
TTGTCGATGTGGCCCCCATCATAGTTGATGGGAAATTAAAGGGAAGTGTTGGAGTTATCCATGATGTTTCTAAAATTAAA
CGTTTAACTGAAGAACTGGATCATGTCAGGAGAATTATCAGGCATTTAAATGCTAAATACACCTTTGAAGATATCATTGG
AGAAAGTGAAACCATGAAGGCTGCCAAAAACCAGGCCAGGAAAGCCTCAAAAACACCGGTTACTGTCTTATTAAGGGGGG
AAAGTGGTACTGGAAAGGAACTTTTTGCTCATGCTATTCATAATGCCAGTCCCCGCCAGAATAATAAATTTATCCGGGTT
AACTGTTCAGCGATTGCTGATAATATCCTGGAAAGTGAATTATTTGGTTATGAAGAGGGGGCCTTTACCGGTGCCAGAAA
GGGTGGTAAAAAGGGGTATTTTGAGGAAGCAGACGGAGGCACTGTTTTCCTGGATGAGATTGGAAAAATCAGTCTGGACC
TCCAGGCTAAACTATTACGGGTCTTACAGGAACGGGAAATTGTAAGGGTTGGTGGGACCAGGCCCAGAAATGTTGATGTT
CGTGTTATAGTAGCGACAAATACCAATCTGGAGCGGGCCATTCAGGAAGGAAACTTCAGAGAAGATTTATATTATCGTCT
TAATGTTTTCCCTCTTCATATTCCACCCCTAAGGGAAAGAAAAGAGGATATACCGTTGCTGGTTCACCATATGATTAGAA
AATTTAATCAGGAATATGGTCGTTCGGTTAAGGGTTGTAGTGAAGATGCCCTTCAGAAATTAAGGGAATACCACTGGCCC
GGTAATGTGAGAGAGCTGGAAAATTTAATAGGTCGGGCCATGATAAATATGGGAATAGAAGAAGAGGTTATCAGGTTAAA
GCATCTCCCATTTTTTGACGGACCGGGGAATAAAAAAACCCGTGAAAATAAAGATGAATTGAATGTTGAAGATCGTTCAT
TGAAAGAAATAGTGGAATCAACCGAGAAAAAAGCTATTATAGAAGCCTTGAATAAAACTGATGGGAACAGGACAGAGGCT
GCTAAATTACTCGGGATAGCAATTAGAAGCCTTTATTATAAGCTTGATAAATACGGGATTGACTGA

Upstream 100 bases:

>100_bases
GAACTGTTACCCCTGTCAAATGACCTGAAGATTGAAGAGGAAATTTTTCCGGTGAAGTTATATAATAATCCACCCTGGAT
AAATAAAAAGGGGTGAAATA

Downstream 100 bases:

>100_bases
TATTTATTTTGAGGACAAGGTTCTGTATAATAGAAAAGATATACCCATAAAACTATAACACTGTATATCAAAGTAATGTG
TAAAAACATGCCTGCATATT

Product: Fis family sigma-54 specific transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 581; Mature: 580

Protein sequence:

>581_residues
MSEKVNFKQLSELNRKTDVILNSTHDGLISIGKDYKVELFNRAAEKILGIKKDRVLGKDVREVIPNTRLHIVLNKGEAEL
NKIQHAGDITIITNRVPVYDEQGNIIGAVAVFRDITEVKKLAEEITNLKEMRTLLEAIINATQDAISVVDEKGIGILINP
AYTRLTGLTEEDVIGKPATVDIAEGESMHYRVLKTKKPVKGVKMKVGPSKKEVIVDVAPIIVDGKLKGSVGVIHDVSKIK
RLTEELDHVRRIIRHLNAKYTFEDIIGESETMKAAKNQARKASKTPVTVLLRGESGTGKELFAHAIHNASPRQNNKFIRV
NCSAIADNILESELFGYEEGAFTGARKGGKKGYFEEADGGTVFLDEIGKISLDLQAKLLRVLQEREIVRVGGTRPRNVDV
RVIVATNTNLERAIQEGNFREDLYYRLNVFPLHIPPLRERKEDIPLLVHHMIRKFNQEYGRSVKGCSEDALQKLREYHWP
GNVRELENLIGRAMINMGIEEEVIRLKHLPFFDGPGNKKTRENKDELNVEDRSLKEIVESTEKKAIIEALNKTDGNRTEA
AKLLGIAIRSLYYKLDKYGID

Sequences:

>Translated_581_residues
MSEKVNFKQLSELNRKTDVILNSTHDGLISIGKDYKVELFNRAAEKILGIKKDRVLGKDVREVIPNTRLHIVLNKGEAEL
NKIQHAGDITIITNRVPVYDEQGNIIGAVAVFRDITEVKKLAEEITNLKEMRTLLEAIINATQDAISVVDEKGIGILINP
AYTRLTGLTEEDVIGKPATVDIAEGESMHYRVLKTKKPVKGVKMKVGPSKKEVIVDVAPIIVDGKLKGSVGVIHDVSKIK
RLTEELDHVRRIIRHLNAKYTFEDIIGESETMKAAKNQARKASKTPVTVLLRGESGTGKELFAHAIHNASPRQNNKFIRV
NCSAIADNILESELFGYEEGAFTGARKGGKKGYFEEADGGTVFLDEIGKISLDLQAKLLRVLQEREIVRVGGTRPRNVDV
RVIVATNTNLERAIQEGNFREDLYYRLNVFPLHIPPLRERKEDIPLLVHHMIRKFNQEYGRSVKGCSEDALQKLREYHWP
GNVRELENLIGRAMINMGIEEEVIRLKHLPFFDGPGNKKTRENKDELNVEDRSLKEIVESTEKKAIIEALNKTDGNRTEA
AKLLGIAIRSLYYKLDKYGID
>Mature_580_residues
SEKVNFKQLSELNRKTDVILNSTHDGLISIGKDYKVELFNRAAEKILGIKKDRVLGKDVREVIPNTRLHIVLNKGEAELN
KIQHAGDITIITNRVPVYDEQGNIIGAVAVFRDITEVKKLAEEITNLKEMRTLLEAIINATQDAISVVDEKGIGILINPA
YTRLTGLTEEDVIGKPATVDIAEGESMHYRVLKTKKPVKGVKMKVGPSKKEVIVDVAPIIVDGKLKGSVGVIHDVSKIKR
LTEELDHVRRIIRHLNAKYTFEDIIGESETMKAAKNQARKASKTPVTVLLRGESGTGKELFAHAIHNASPRQNNKFIRVN
CSAIADNILESELFGYEEGAFTGARKGGKKGYFEEADGGTVFLDEIGKISLDLQAKLLRVLQEREIVRVGGTRPRNVDVR
VIVATNTNLERAIQEGNFREDLYYRLNVFPLHIPPLRERKEDIPLLVHHMIRKFNQEYGRSVKGCSEDALQKLREYHWPG
NVRELENLIGRAMINMGIEEEVIRLKHLPFFDGPGNKKTRENKDELNVEDRSLKEIVESTEKKAIIEALNKTDGNRTEAA
KLLGIAIRSLYYKLDKYGID

Specific function: Member Of The Two-Component Regulatory System Atos/Atoc Involved In The Transcriptional Regulation Of The Ato Genes For Acetoacetate Metabolism. Also An Inhibitor Of Polyamine Biosynthesis. [C]

COG id: COG3829

COG function: function code KT; Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=345, Percent_Identity=45.5072463768116, Blast_Score=285, Evalue=4e-78,
Organism=Escherichia coli, GI1789233, Length=471, Percent_Identity=35.8811040339703, Blast_Score=275, Evalue=8e-75,
Organism=Escherichia coli, GI1790437, Length=313, Percent_Identity=44.408945686901, Blast_Score=261, Evalue=6e-71,
Organism=Escherichia coli, GI87082117, Length=332, Percent_Identity=42.4698795180723, Blast_Score=259, Evalue=2e-70,
Organism=Escherichia coli, GI1790299, Length=343, Percent_Identity=43.1486880466472, Blast_Score=259, Evalue=2e-70,
Organism=Escherichia coli, GI1788905, Length=322, Percent_Identity=42.5465838509317, Blast_Score=246, Evalue=3e-66,
Organism=Escherichia coli, GI1789087, Length=254, Percent_Identity=48.4251968503937, Blast_Score=243, Evalue=2e-65,
Organism=Escherichia coli, GI1786524, Length=377, Percent_Identity=37.6657824933687, Blast_Score=243, Evalue=3e-65,
Organism=Escherichia coli, GI87082152, Length=320, Percent_Identity=40.9375, Blast_Score=226, Evalue=2e-60,
Organism=Escherichia coli, GI1787583, Length=320, Percent_Identity=39.0625, Blast_Score=212, Evalue=6e-56,
Organism=Escherichia coli, GI87081872, Length=332, Percent_Identity=36.7469879518072, Blast_Score=199, Evalue=4e-52,
Organism=Escherichia coli, GI87081858, Length=507, Percent_Identity=27.6134122287968, Blast_Score=182, Evalue=5e-47,
Organism=Escherichia coli, GI1789828, Length=244, Percent_Identity=33.6065573770492, Blast_Score=132, Evalue=7e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR002197
- InterPro:   IPR016040
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00989 PAS; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 65363; Mature: 65232

Theoretical pI: Translated: 9.49; Mature: 9.49

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEKVNFKQLSELNRKTDVILNSTHDGLISIGKDYKVELFNRAAEKILGIKKDRVLGKDV
CCCCCCHHHHHHCCCHHCEEEECCCCCCEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHH
REVIPNTRLHIVLNKGEAELNKIQHAGDITIITNRVPVYDEQGNIIGAVAVFRDITEVKK
HHHCCCCEEEEEEECCCHHHHHHHCCCCEEEEECCCCCEECCCCEEEHHHHHHHHHHHHH
LAEEITNLKEMRTLLEAIINATQDAISVVDEKGIGILINPAYTRLTGLTEEDVIGKPATV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHCCCCHHHCCCCCCEE
DIAEGESMHYRVLKTKKPVKGVKMKVGPSKKEVIVDVAPIIVDGKLKGSVGVIHDVSKIK
EECCCCCEEEEEECCCCCCCCCEEEECCCCCEEEEEEECEEECCCCCCCCHHHHHHHHHH
RLTEELDHVRRIIRHLNAKYTFEDIIGESETMKAAKNQARKASKTPVTVLLRGESGTGKE
HHHHHHHHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHH
LFAHAIHNASPRQNNKFIRVNCSAIADNILESELFGYEEGAFTGARKGGKKGYFEEADGG
HHHHHHHCCCCCCCCCEEEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
TVFLDEIGKISLDLQAKLLRVLQEREIVRVGGTRPRNVDVRVIVATNTNLERAIQEGNFR
EEEEECCCCEEEHHHHHHHHHHHHCCEEEECCCCCCCCEEEEEEEECCCHHHHHHCCCCC
EDLYYRLNVFPLHIPPLRERKEDIPLLVHHMIRKFNQEYGRSVKGCSEDALQKLREYHWP
CCEEEEEEEEEEECCCHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCC
GNVRELENLIGRAMINMGIEEEVIRLKHLPFFDGPGNKKTRENKDELNVEDRSLKEIVES
CCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCCCHHCCCCHHHHHHHHHH
TEKKAIIEALNKTDGNRTEAAKLLGIAIRSLYYKLDKYGID
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SEKVNFKQLSELNRKTDVILNSTHDGLISIGKDYKVELFNRAAEKILGIKKDRVLGKDV
CCCCCHHHHHHCCCHHCEEEECCCCCCEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHH
REVIPNTRLHIVLNKGEAELNKIQHAGDITIITNRVPVYDEQGNIIGAVAVFRDITEVKK
HHHCCCCEEEEEEECCCHHHHHHHCCCCEEEEECCCCCEECCCCEEEHHHHHHHHHHHHH
LAEEITNLKEMRTLLEAIINATQDAISVVDEKGIGILINPAYTRLTGLTEEDVIGKPATV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHCCCCHHHCCCCCCEE
DIAEGESMHYRVLKTKKPVKGVKMKVGPSKKEVIVDVAPIIVDGKLKGSVGVIHDVSKIK
EECCCCCEEEEEECCCCCCCCCEEEECCCCCEEEEEEECEEECCCCCCCCHHHHHHHHHH
RLTEELDHVRRIIRHLNAKYTFEDIIGESETMKAAKNQARKASKTPVTVLLRGESGTGKE
HHHHHHHHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHH
LFAHAIHNASPRQNNKFIRVNCSAIADNILESELFGYEEGAFTGARKGGKKGYFEEADGG
HHHHHHHCCCCCCCCCEEEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
TVFLDEIGKISLDLQAKLLRVLQEREIVRVGGTRPRNVDVRVIVATNTNLERAIQEGNFR
EEEEECCCCEEEHHHHHHHHHHHHCCEEEECCCCCCCCEEEEEEEECCCHHHHHHCCCCC
EDLYYRLNVFPLHIPPLRERKEDIPLLVHHMIRKFNQEYGRSVKGCSEDALQKLREYHWP
CCEEEEEEEEEEECCCHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCC
GNVRELENLIGRAMINMGIEEEVIRLKHLPFFDGPGNKKTRENKDELNVEDRSLKEIVES
CCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCCCHHCCCCHHHHHHHHHH
TEKKAIIEALNKTDGNRTEAAKLLGIAIRSLYYKLDKYGID
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]