Click here to switch to the map view.

The map label for this gene is ldh [H]

Identifier: 220931517

GI number: 220931517

Start: 730992

End: 732056

Strand: Direct

Name: ldh [H]

Synonym: Hore_06730

Alternate gene names: 220931517

Gene position: 730992-732056 (Clockwise)

Preceding gene: 220931516

Following gene: 220931518

Centisome position: 28.35

GC content: 40.0

Gene sequence:

>1065_bases
ATGGAAATATTTAAAGAGATGGCAAAAGAGGGACATGAACAGATAATATTTTTCCAGGAAAAGAAAACCGGTCTCAAATC
CATAGTTGCAATTCATAACACAGTATTAGGACCGGGACTGGGTGGTTGTCGTATGTGGCCTTATAAAACTGAAGAAGAGG
CCCTGAAGGATGCCATGCGTTTATCAAAAGGTATGACTTATAAATCTGCCATTGCTGGAGAAGACTTTGGTGGTGCCAAA
ACGGTAATCTGGGGGGATCCGGAGACTGATAAAAGTGAGGGGCTTTTCAGGGTTCTGGGTCGGTATATAAATGGTCTCGG
GGGTCGTTATAGTACCGGAACAGATGTCGGAACCACCTATGATGATTTTGTAATATTAAATAAAGAAACACCATATGTTG
GAGCTCTGCCGAAGGAATATGGTGGTAGTGGTGATTCATCCATTCCAACTGCATACGGTGTTTATAATGGGATTAAGGCC
TGTTGTAAATATAAATATGGAAGTGATTCATTAGAGGGGAAAACAGTTGCTATTCAGGGGTTAGGTAAAGTAGGCTATAA
GCTGGCTAAACATCTACTTGAAGAGGGCTGTAAAGTTTATGGTACTGATATCAAAGAAGAATATCTGGAAAGGGCCCGCC
AGCTGGGGGTAGACATAGTAAAAACTGATGAAATTTATGATATTGACTGTGACATCTTCTCTCCAAATGCCCTGGGTGCT
GTTATAAATGATAATACTATTGAAAGACTTAAATGTGATATTGTAGCCGGGGCTGCCAATAATGTTCTGGCTGAACCACG
CCACGGTGAAATGTTACATCAGAAAGGGATATTATATGCCCCTGATTATGTAATAAATGGTGGTGGTCTAATTCAGGTGG
CCGATGAACTTGGAAACGAAACCTATAGTGAAGAGAGGGTAATGAGAAAGTGTGAGGGTATTTATAATCAATTATTGAAA
ATATTTAAGCTGGCAGAAGAAAAAGATATTCCAACTCATGCGGCTGCTGACCATATTGTTGAAGAAAGAATCGAGACTAT
AGCTACAATTCACAGGATTAAATAA

Upstream 100 bases:

>100_bases
AATTTATAGTAAATAAAAAAATGTGACAGGTCTGGCACGCTATATGCAATTATAATTAGTAGAACAATATTAAGTAAATA
AAAAAAAGGGGGGGGAAGTA

Downstream 100 bases:

>100_bases
GGTGGGGGATATAAATGTTTAAAAATGTAGCTGAATTTATTGAAAAGGCCAGTAACCCTCCAGTTTTAAAATTAGCGGTG
GCGGCTGCCGGTGATGAAGA

Product: Leucine dehydrogenase

Products: NA

Alternate protein names: LeuDH [H]

Number of amino acids: Translated: 354; Mature: 354

Protein sequence:

>354_residues
MEIFKEMAKEGHEQIIFFQEKKTGLKSIVAIHNTVLGPGLGGCRMWPYKTEEEALKDAMRLSKGMTYKSAIAGEDFGGAK
TVIWGDPETDKSEGLFRVLGRYINGLGGRYSTGTDVGTTYDDFVILNKETPYVGALPKEYGGSGDSSIPTAYGVYNGIKA
CCKYKYGSDSLEGKTVAIQGLGKVGYKLAKHLLEEGCKVYGTDIKEEYLERARQLGVDIVKTDEIYDIDCDIFSPNALGA
VINDNTIERLKCDIVAGAANNVLAEPRHGEMLHQKGILYAPDYVINGGGLIQVADELGNETYSEERVMRKCEGIYNQLLK
IFKLAEEKDIPTHAAADHIVEERIETIATIHRIK

Sequences:

>Translated_354_residues
MEIFKEMAKEGHEQIIFFQEKKTGLKSIVAIHNTVLGPGLGGCRMWPYKTEEEALKDAMRLSKGMTYKSAIAGEDFGGAK
TVIWGDPETDKSEGLFRVLGRYINGLGGRYSTGTDVGTTYDDFVILNKETPYVGALPKEYGGSGDSSIPTAYGVYNGIKA
CCKYKYGSDSLEGKTVAIQGLGKVGYKLAKHLLEEGCKVYGTDIKEEYLERARQLGVDIVKTDEIYDIDCDIFSPNALGA
VINDNTIERLKCDIVAGAANNVLAEPRHGEMLHQKGILYAPDYVINGGGLIQVADELGNETYSEERVMRKCEGIYNQLLK
IFKLAEEKDIPTHAAADHIVEERIETIATIHRIK
>Mature_354_residues
MEIFKEMAKEGHEQIIFFQEKKTGLKSIVAIHNTVLGPGLGGCRMWPYKTEEEALKDAMRLSKGMTYKSAIAGEDFGGAK
TVIWGDPETDKSEGLFRVLGRYINGLGGRYSTGTDVGTTYDDFVILNKETPYVGALPKEYGGSGDSSIPTAYGVYNGIKA
CCKYKYGSDSLEGKTVAIQGLGKVGYKLAKHLLEEGCKVYGTDIKEEYLERARQLGVDIVKTDEIYDIDCDIFSPNALGA
VINDNTIERLKCDIVAGAANNVLAEPRHGEMLHQKGILYAPDYVINGGGLIQVADELGNETYSEERVMRKCEGIYNQLLK
IFKLAEEKDIPTHAAADHIVEERIETIATIHRIK

Specific function: Functions catabolically in the bacterial metabolism of branched-chain L-amino acids. Catalyzes the reversible deamination of these branched-chain L-amino acids to their oxo analogs [H]

COG id: COG0334

COG function: function code E; Glutamate dehydrogenase/leucine dehydrogenase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Glu/Leu/Phe/Val dehydrogenases family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006095
- InterPro:   IPR006096
- InterPro:   IPR006097
- InterPro:   IPR016211
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00208 ELFV_dehydrog; PF02812 ELFV_dehydrog_N [H]

EC number: =1.4.1.9 [H]

Molecular weight: Translated: 38997; Mature: 38997

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIFKEMAKEGHEQIIFFQEKKTGLKSIVAIHNTVLGPGLGGCRMWPYKTEEEALKDAMR
CHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHH
LSKGMTYKSAIAGEDFGGAKTVIWGDPETDKSEGLFRVLGRYINGLGGRYSTGTDVGTTY
HHHCCCHHHHHCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCC
DDFVILNKETPYVGALPKEYGGSGDSSIPTAYGVYNGIKACCKYKYGSDSLEGKTVAIQG
CCEEEECCCCCCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEC
LGKVGYKLAKHLLEEGCKVYGTDIKEEYLERARQLGVDIVKTDEIYDIDCDIFSPNALGA
CHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHCCCEEEECCCEEEECCCEECCCCCEE
VINDNTIERLKCDIVAGAANNVLAEPRHGEMLHQKGILYAPDYVINGGGLIQVADELGNE
EECCCHHHHHEEEEEECCCCCCCCCCCCCHHHHHCCCEECCCEEECCCCEEEEHHHHCCC
TYSEERVMRKCEGIYNQLLKIFKLAEEKDIPTHAAADHIVEERIETIATIHRIK
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEIFKEMAKEGHEQIIFFQEKKTGLKSIVAIHNTVLGPGLGGCRMWPYKTEEEALKDAMR
CHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHH
LSKGMTYKSAIAGEDFGGAKTVIWGDPETDKSEGLFRVLGRYINGLGGRYSTGTDVGTTY
HHHCCCHHHHHCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCC
DDFVILNKETPYVGALPKEYGGSGDSSIPTAYGVYNGIKACCKYKYGSDSLEGKTVAIQG
CCEEEECCCCCCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEC
LGKVGYKLAKHLLEEGCKVYGTDIKEEYLERARQLGVDIVKTDEIYDIDCDIFSPNALGA
CHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHCCCEEEECCCEEEECCCEECCCCCEE
VINDNTIERLKCDIVAGAANNVLAEPRHGEMLHQKGILYAPDYVINGGGLIQVADELGNE
EECCCHHHHHEEEEEECCCCCCCCCCCCCHHHHHCCCEECCCEEECCCCEEEEHHHHCCC
TYSEERVMRKCEGIYNQLLKIFKLAEEKDIPTHAAADHIVEERIETIATIHRIK
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8020469 [H]